JPS6452740A - Production of omega-hydroxyfatty acid ester - Google Patents
Production of omega-hydroxyfatty acid esterInfo
- Publication number
- JPS6452740A JPS6452740A JP20836387A JP20836387A JPS6452740A JP S6452740 A JPS6452740 A JP S6452740A JP 20836387 A JP20836387 A JP 20836387A JP 20836387 A JP20836387 A JP 20836387A JP S6452740 A JPS6452740 A JP S6452740A
- Authority
- JP
- Japan
- Prior art keywords
- diborane
- alkaline
- earth metal
- formula
- reducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To obtain the titled compound useful as an intermediate for a macrocyclic lactone having musk-like odor and useful as a raw material for perfumery, in high efficiency, by reducing an easily available alkaline-earth metal salt of a dibasic acid monoester with diborane. CONSTITUTION:The objective compound of formula II (e.g. 12-hydroxy- dodecanoic acid methyl ester) can be produced by reducing (A) 1mol. of an alkaline-earth metal salt of a dibasic acid monoester of formula I (R is ester residue; n is 10-16; M is alkaline-earth metal) (e.g. barium salt of dodecanoic diacid monomethyl ester) with (B) 2.0-3.0mol. equivalent of diborane preferably in a solvent such as tetrahydrofuran (THF) at 0-80 deg.C, especially preferably 20-60 deg.C. The diborane may be commercially available diborane-THF complex solution or may be the one generated in the reaction system e.g. by reacting NaBH4 with dimethyl sulfate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20836387A JPS6452740A (en) | 1987-08-24 | 1987-08-24 | Production of omega-hydroxyfatty acid ester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20836387A JPS6452740A (en) | 1987-08-24 | 1987-08-24 | Production of omega-hydroxyfatty acid ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6452740A true JPS6452740A (en) | 1989-02-28 |
Family
ID=16555051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP20836387A Pending JPS6452740A (en) | 1987-08-24 | 1987-08-24 | Production of omega-hydroxyfatty acid ester |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6452740A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63177132A (en) * | 1987-01-19 | 1988-07-21 | Fuji Photo Film Co Ltd | Processing of silver halide photographic sensitive material |
-
1987
- 1987-08-24 JP JP20836387A patent/JPS6452740A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63177132A (en) * | 1987-01-19 | 1988-07-21 | Fuji Photo Film Co Ltd | Processing of silver halide photographic sensitive material |
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