JPS5452087A - Cytidine derivative and its prepareation - Google Patents
Cytidine derivative and its prepareationInfo
- Publication number
- JPS5452087A JPS5452087A JP11832277A JP11832277A JPS5452087A JP S5452087 A JPS5452087 A JP S5452087A JP 11832277 A JP11832277 A JP 11832277A JP 11832277 A JP11832277 A JP 11832277A JP S5452087 A JPS5452087 A JP S5452087A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- iminopyrimidine
- arabinofuranosyl
- dihydro
- prepareation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:1-β-D-arabinofuranosy1-2-substituted-1,4-dihydro-iminopyrimidine salt of formula I (R is aralkyl, pyridylalkyl; X is anion residue of a pharmacologically permissible acid).
EXAMPLE: 1-β-D-arabinofuranosyl-2-benzylamino-1,4-dihydro-4-iminopyrimidine hydrochloric acid salt 1/2 hydrate.
USE: Anti-viral agent. Stable in aqueous solution. Easily be converted to another pharmacologically permissible inorganic or organic salt by ion exchange resin treatment, etc.
PROCESS: The compound I is prepared by reacting an amine II with 2,2'-anhydro- 1-(β-D-arabinofuranosyl) cytosine salt III in a solvent such as methanol, at room temperature
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11832277A JPS5452087A (en) | 1977-09-30 | 1977-09-30 | Cytidine derivative and its prepareation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11832277A JPS5452087A (en) | 1977-09-30 | 1977-09-30 | Cytidine derivative and its prepareation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5452087A true JPS5452087A (en) | 1979-04-24 |
Family
ID=14733790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11832277A Pending JPS5452087A (en) | 1977-09-30 | 1977-09-30 | Cytidine derivative and its prepareation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5452087A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107216362A (en) * | 2017-06-12 | 2017-09-29 | 山东大学 | A kind of cytarabine amphipathic small molecules prodrug and its preparation method and application |
-
1977
- 1977-09-30 JP JP11832277A patent/JPS5452087A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107216362A (en) * | 2017-06-12 | 2017-09-29 | 山东大学 | A kind of cytarabine amphipathic small molecules prodrug and its preparation method and application |
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