HU9800781D0 - Propanolamine derivatives, process for producing them, pharmaceutical compositions containing them and their use - Google Patents
Propanolamine derivatives, process for producing them, pharmaceutical compositions containing them and their useInfo
- Publication number
- HU9800781D0 HU9800781D0 HU9800781A HUP9800781A HU9800781D0 HU 9800781 D0 HU9800781 D0 HU 9800781D0 HU 9800781 A HU9800781 A HU 9800781A HU P9800781 A HUP9800781 A HU P9800781A HU 9800781 D0 HU9800781 D0 HU 9800781D0
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- pharmaceutical compositions
- compositions containing
- propanolamine derivatives
- propanolamine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003152 propanolamines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Obesity (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19713865 | 1997-04-04 | ||
DE1998102530 DE19802530A1 (de) | 1998-01-26 | 1998-01-26 | Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9800781D0 true HU9800781D0 (en) | 1998-05-28 |
HUP9800781A2 HUP9800781A2 (hu) | 1999-06-28 |
HUP9800781A3 HUP9800781A3 (en) | 1999-07-28 |
Family
ID=26035472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9800781A HUP9800781A3 (en) | 1997-04-04 | 1998-04-03 | Propanolamine derivatives, process for producing them, pharmaceutical compositions containing them and their use |
Country Status (24)
Country | Link |
---|---|
US (1) | US5874451A (hu) |
EP (1) | EP0869121B1 (hu) |
JP (1) | JP4234805B2 (hu) |
KR (1) | KR19980081055A (hu) |
CN (1) | CN1185217C (hu) |
AR (1) | AR011210A1 (hu) |
AT (1) | ATE268758T1 (hu) |
AU (1) | AU730228B2 (hu) |
BR (1) | BR9801150A (hu) |
CA (1) | CA2233925A1 (hu) |
CZ (1) | CZ293758B6 (hu) |
DE (1) | DE59811528D1 (hu) |
DK (1) | DK0869121T3 (hu) |
ES (1) | ES2223091T3 (hu) |
HK (1) | HK1015789A1 (hu) |
HU (1) | HUP9800781A3 (hu) |
ID (1) | ID20137A (hu) |
IL (1) | IL123927A (hu) |
MY (1) | MY114944A (hu) |
NZ (1) | NZ330110A (hu) |
PL (1) | PL325699A1 (hu) |
PT (1) | PT869121E (hu) |
RU (1) | RU2198876C2 (hu) |
TR (1) | TR199800608A2 (hu) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
US6489344B1 (en) | 1998-06-19 | 2002-12-03 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
DE19845403B4 (de) | 1998-10-02 | 2005-02-10 | Aventis Pharma Deutschland Gmbh | Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
DE19845405C2 (de) | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
DE19845406C2 (de) * | 1998-10-02 | 2001-10-18 | Aventis Pharma Gmbh | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
CZ20031733A3 (cs) * | 2000-12-21 | 2003-09-17 | Aventis Pharma Deutschland Gmbh | Difenylazetidinonové deriváty a farmaceutické prostředky s jejich obsahem |
HUP0401908A2 (hu) * | 2001-08-22 | 2005-01-28 | Aventis Pharma Deutschland Gmbh | Arilszubsztituált propanolaminszármazékokat tartalmazó kombinációs készítmények, alkalmazásuk és előállítási eljárásuk |
AU2003241836A1 (en) | 2002-10-03 | 2004-04-23 | Ono Pharmaceutical Co., Ltd. | Lpa receptor antagonists |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
US7875745B2 (en) | 2003-12-19 | 2011-01-25 | Ono Pharmaceutical Co., Ltd. | Compounds having lysophosphatidic acid receptor antagonism and uses thereof |
CN1869002A (zh) * | 2005-05-27 | 2006-11-29 | 中国科学院上海药物研究所 | 一类非甾体雄激素受体调节剂、其制备方法和用途 |
EP2099774A4 (en) * | 2006-11-15 | 2010-11-24 | Ym Biosciences Australia Pty L | INHIBITORS OF KINASEACTIVITY |
WO2011150286A2 (en) | 2010-05-26 | 2011-12-01 | Satiogen Pharmaceuticals,Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
KR102051030B1 (ko) | 2011-10-28 | 2019-12-02 | 루메나 파마수티컬즈, 인코포레이티드 | 소아 담즙울체성 간 질환 치료용 담즙산 재순환 억제제 |
CN104023718B (zh) | 2011-10-28 | 2017-04-05 | 鲁美纳医药公司 | 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 |
US20140275090A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
CA2907214A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
CN105553262B (zh) * | 2015-08-24 | 2018-02-16 | 苏州瑞铬优电子科技有限公司 | 一种提高dc/dc升压变换器转换效率的方法 |
CA3129827A1 (en) | 2019-02-12 | 2020-08-20 | Mirum Pharmaceuticals, Inc. | Genotype and dose-dependent response to an asbti in patients with bile salt export pump deficiency |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
US5250524A (en) * | 1990-12-06 | 1993-10-05 | Hoechst Aktiengesellschaft | Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals |
GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
DK0557879T3 (da) * | 1992-02-22 | 1997-06-16 | Hoechst Ag | 4-amino-2-ureido-pyrimidin-5-carboxylsyreamider, fremgangsmåde til deres fremstilling, lægemidler med indhold af disse forbindelser og deres anvendelse |
-
1998
- 1998-03-24 DE DE59811528T patent/DE59811528D1/de not_active Expired - Lifetime
- 1998-03-24 PT PT98105256T patent/PT869121E/pt unknown
- 1998-03-24 DK DK98105256T patent/DK0869121T3/da active
- 1998-03-24 ES ES98105256T patent/ES2223091T3/es not_active Expired - Lifetime
- 1998-03-24 AT AT98105256T patent/ATE268758T1/de not_active IP Right Cessation
- 1998-03-24 EP EP98105256A patent/EP0869121B1/de not_active Expired - Lifetime
- 1998-04-02 US US09/053,513 patent/US5874451A/en not_active Expired - Lifetime
- 1998-04-02 ID IDP980494A patent/ID20137A/id unknown
- 1998-04-02 TR TR1998/00608A patent/TR199800608A2/xx unknown
- 1998-04-02 NZ NZ330110A patent/NZ330110A/xx unknown
- 1998-04-02 AR ARP980101512A patent/AR011210A1/es unknown
- 1998-04-02 IL IL12392798A patent/IL123927A/xx active IP Right Grant
- 1998-04-03 AU AU60624/98A patent/AU730228B2/en not_active Ceased
- 1998-04-03 JP JP10716198A patent/JP4234805B2/ja not_active Expired - Fee Related
- 1998-04-03 PL PL98325699A patent/PL325699A1/xx not_active Application Discontinuation
- 1998-04-03 CN CNB981082521A patent/CN1185217C/zh not_active Expired - Fee Related
- 1998-04-03 CA CA002233925A patent/CA2233925A1/en not_active Abandoned
- 1998-04-03 MY MYPI98001488A patent/MY114944A/en unknown
- 1998-04-03 HU HU9800781A patent/HUP9800781A3/hu unknown
- 1998-04-03 KR KR1019980011750A patent/KR19980081055A/ko active IP Right Grant
- 1998-04-03 RU RU98106112/04A patent/RU2198876C2/ru not_active IP Right Cessation
- 1998-04-03 CZ CZ19981025A patent/CZ293758B6/cs not_active IP Right Cessation
- 1998-04-06 BR BR9801150A patent/BR9801150A/pt not_active IP Right Cessation
-
1999
- 1999-03-12 HK HK99101018A patent/HK1015789A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL325699A1 (en) | 1998-10-12 |
CN1185217C (zh) | 2005-01-19 |
TR199800608A3 (tr) | 1998-10-21 |
DE59811528D1 (de) | 2004-07-15 |
JP4234805B2 (ja) | 2009-03-04 |
AR011210A1 (es) | 2000-08-02 |
KR19980081055A (ko) | 1998-11-25 |
MY114944A (en) | 2003-02-28 |
HK1015789A1 (en) | 1999-10-22 |
CN1199731A (zh) | 1998-11-25 |
AU730228B2 (en) | 2001-03-01 |
CZ102598A3 (cs) | 1998-10-14 |
NZ330110A (en) | 1999-03-29 |
JPH10287651A (ja) | 1998-10-27 |
DK0869121T3 (da) | 2004-09-20 |
ID20137A (id) | 1998-10-08 |
CZ293758B6 (cs) | 2004-07-14 |
EP0869121B1 (de) | 2004-06-09 |
ES2223091T3 (es) | 2005-02-16 |
EP0869121A1 (de) | 1998-10-07 |
ATE268758T1 (de) | 2004-06-15 |
CA2233925A1 (en) | 1998-10-04 |
TR199800608A2 (en) | 1998-10-21 |
BR9801150A (pt) | 2000-03-21 |
PT869121E (pt) | 2004-10-29 |
RU2198876C2 (ru) | 2003-02-20 |
HUP9800781A3 (en) | 1999-07-28 |
HUP9800781A2 (hu) | 1999-06-28 |
AU6062498A (en) | 1998-10-08 |
US5874451A (en) | 1999-02-23 |
IL123927A (en) | 2001-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |