FR2794473B1 - Procede de multiplication de cellules souches - Google Patents

Procede de multiplication de cellules souches

Info

Publication number
FR2794473B1
FR2794473B1 FR9907011A FR9907011A FR2794473B1 FR 2794473 B1 FR2794473 B1 FR 2794473B1 FR 9907011 A FR9907011 A FR 9907011A FR 9907011 A FR9907011 A FR 9907011A FR 2794473 B1 FR2794473 B1 FR 2794473B1
Authority
FR
France
Prior art keywords
stem cells
multiplying
multiplying stem
cells
stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9907011A
Other languages
English (en)
Other versions
FR2794473A1 (fr
Inventor
Jacques Alexandre Hatzfeld
Antoinette Klein Hatzfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9907011A priority Critical patent/FR2794473B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to CA002375485A priority patent/CA2375485A1/fr
Priority to US09/980,484 priority patent/US7601534B1/en
Priority to PCT/FR2000/001486 priority patent/WO2000075290A1/fr
Priority to JP2001502556A priority patent/JP2003501081A/ja
Priority to EP00936985A priority patent/EP1181354A1/fr
Publication of FR2794473A1 publication Critical patent/FR2794473A1/fr
Application granted granted Critical
Publication of FR2794473B1 publication Critical patent/FR2794473B1/fr
Priority to US12/555,062 priority patent/US20090325289A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR9907011A 1999-06-03 1999-06-03 Procede de multiplication de cellules souches Expired - Fee Related FR2794473B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9907011A FR2794473B1 (fr) 1999-06-03 1999-06-03 Procede de multiplication de cellules souches
US09/980,484 US7601534B1 (en) 1999-06-03 2000-05-30 Method for multiplying stem cells
PCT/FR2000/001486 WO2000075290A1 (fr) 1999-06-03 2000-05-30 Procede de multiplication de cellules souches
JP2001502556A JP2003501081A (ja) 1999-06-03 2000-05-30 幹細胞の増殖工程
CA002375485A CA2375485A1 (fr) 1999-06-03 2000-05-30 Procede de multiplication de cellules souches
EP00936985A EP1181354A1 (fr) 1999-06-03 2000-05-30 Procede de multiplication de cellules souches
US12/555,062 US20090325289A1 (en) 1999-06-03 2009-09-08 Process for the multiplication of stem cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907011A FR2794473B1 (fr) 1999-06-03 1999-06-03 Procede de multiplication de cellules souches

Publications (2)

Publication Number Publication Date
FR2794473A1 FR2794473A1 (fr) 2000-12-08
FR2794473B1 true FR2794473B1 (fr) 2003-09-26

Family

ID=9546326

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9907011A Expired - Fee Related FR2794473B1 (fr) 1999-06-03 1999-06-03 Procede de multiplication de cellules souches

Country Status (6)

Country Link
US (2) US7601534B1 (fr)
EP (1) EP1181354A1 (fr)
JP (1) JP2003501081A (fr)
CA (1) CA2375485A1 (fr)
FR (1) FR2794473B1 (fr)
WO (1) WO2000075290A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846898B2 (en) 2004-02-13 2010-12-07 Stem Cell Therapeutics Corp. Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
EP2319531A3 (fr) * 2004-10-07 2011-09-07 Stem Cell Therapeutics Corp. Stimulation de la proliferation de cellules souches pluripotentes par administration de composés associés à la gestation
AU2007229301B2 (en) * 2006-03-17 2013-08-01 Stem Cell Therapeutics Corp. Continuous dosing regimens for neural stem cell proliferating agents and neural stem cell differentiating agents
EP2412800A1 (fr) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Organoïde du foie, ses utilisations et son procédé de culture pour l'obtenir
GB201111244D0 (en) * 2011-06-30 2011-08-17 Konink Nl Akademie Van Wetenschappen Knaw Culture media for stem cells
CA2751332C (fr) 2009-02-03 2024-04-02 Koninklijke Nederlandse Akademie Van Wetenschappen Milieu de culture pour cellules souches epitheliales et organoides comprenant lesdites cellules souches
WO2011069091A1 (fr) 2009-12-04 2011-06-09 Boston Biomedical Research Institute, Inc. Procédé de clonage de cellules souches pluripotentes
US9164079B2 (en) * 2011-03-17 2015-10-20 Greyledge Technologies Llc Systems for autologous biological therapeutics
JP6095272B2 (ja) 2011-03-25 2017-03-15 国立大学法人京都大学 上皮系体性幹細胞の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08205860A (ja) * 1994-01-21 1996-08-13 Usa Government 造血細胞の膨大化および移植方法
DE4422667A1 (de) * 1994-06-30 1996-01-04 Boehringer Ingelheim Int Verfahren zur Herstellung und Züchtung hämatopoetischer Vorläuferzellen
CA2248142A1 (fr) * 1996-03-12 1997-09-18 Life Technologies, Inc. Additif pour milieu de culture nutritif pour cellules hematopoietiques
EP0834556A1 (fr) * 1996-09-25 1998-04-08 Academisch Ziekenhuis Leiden Procédés de culture de cellules
JPH10136978A (ja) * 1996-11-08 1998-05-26 Otsuka Pharmaceut Co Ltd 造血幹細胞の培養方法
US6084060A (en) * 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
JPH10295369A (ja) * 1997-02-26 1998-11-10 Japan Tobacco Inc 造血幹細胞の製造方法

Also Published As

Publication number Publication date
EP1181354A1 (fr) 2002-02-27
US7601534B1 (en) 2009-10-13
FR2794473A1 (fr) 2000-12-08
JP2003501081A (ja) 2003-01-14
WO2000075290A1 (fr) 2000-12-14
CA2375485A1 (fr) 2000-12-14
US20090325289A1 (en) 2009-12-31

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Legal Events

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ST Notification of lapse

Effective date: 20120229