FR2358391A1 - PROSTAGLANDIN-ANALOGUE CYCLOHEXANE DERIVATIVES - Google Patents

PROSTAGLANDIN-ANALOGUE CYCLOHEXANE DERIVATIVES

Info

Publication number
FR2358391A1
FR2358391A1 FR7721634A FR7721634A FR2358391A1 FR 2358391 A1 FR2358391 A1 FR 2358391A1 FR 7721634 A FR7721634 A FR 7721634A FR 7721634 A FR7721634 A FR 7721634A FR 2358391 A1 FR2358391 A1 FR 2358391A1
Authority
FR
France
Prior art keywords
prostaglandin
analogue
cyclohexane derivatives
compounds
cyclohexane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7721634A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Glaxo Laboratories Ltd
Original Assignee
Laboratoires Glaxo SA
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA, Glaxo Laboratories Ltd filed Critical Laboratoires Glaxo SA
Publication of FR2358391A1 publication Critical patent/FR2358391A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/02—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains containing only carbon and hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C07C403/16—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms not being part of —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0058—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring
    • C07C405/0066—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring to a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des composés analogues aux prostaglandines. Les composés conformes à l'invention répondent à la formule générale qui suit :The invention relates to compounds analogous to prostaglandins. The compounds in accordance with the invention correspond to the following general formula:

FR7721634A 1976-07-13 1977-07-13 PROSTAGLANDIN-ANALOGUE CYCLOHEXANE DERIVATIVES Withdrawn FR2358391A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29166/76A GB1583146A (en) 1976-07-13 1976-07-13 Homoprostaglandins

Publications (1)

Publication Number Publication Date
FR2358391A1 true FR2358391A1 (en) 1978-02-10

Family

ID=10287181

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721634A Withdrawn FR2358391A1 (en) 1976-07-13 1977-07-13 PROSTAGLANDIN-ANALOGUE CYCLOHEXANE DERIVATIVES

Country Status (6)

Country Link
JP (1) JPS5328148A (en)
BE (1) BE856739A (en)
DE (1) DE2731459A1 (en)
FR (1) FR2358391A1 (en)
GB (1) GB1583146A (en)
NL (1) NL7707731A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
DE3280020D1 (en) * 1981-12-23 1989-12-21 Nat Res Dev Prostaglandins
US4837234A (en) * 1981-12-23 1989-06-06 National Research Development Corporation Prostaglandins
US6638486B2 (en) 2000-03-08 2003-10-28 Nippon Shokubai Co., Ltd. Catalyst for purification of exhaust gases, production process therefor, and process for purification of exhaust gases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2145601A1 (en) * 1971-07-14 1973-02-23 American Cyanamid Co Prostaglandin analogues - with gastric secretion inhibiting bronchodilatory, hypotensive etc activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2145601A1 (en) * 1971-07-14 1973-02-23 American Cyanamid Co Prostaglandin analogues - with gastric secretion inhibiting bronchodilatory, hypotensive etc activity

Also Published As

Publication number Publication date
DE2731459A1 (en) 1978-01-19
NL7707731A (en) 1978-01-17
GB1583146A (en) 1981-01-21
BE856739A (en) 1978-01-12
JPS5328148A (en) 1978-03-16

Similar Documents

Publication Publication Date Title
FR2354316A1 (en) NEW NON-IONIC IODINE CONTRAST AGENTS
FR2442849A1 (en)
IT1076361B (en) COCKPIT, ESPECIALLY FOR THE CONSTRUCTION OF SEWERS, AS WELL AS THE PROCEDURE FOR THE CONSTRUCTION OF THE SAME
FR2453145A1 (en)
FR2359820A1 (en) NON-MIGRATORY ANTIOXIDANTS CONTAINING SULFONYL AZIDE
FR2362134A1 (en) CYCLOPROPYLAMINO-2 DIAMINO-4,6-TRIAZINES-1,3,5 AND INSECTICIDAL PRODUCTS CONTAINING IT
FR2375239A1 (en) 7-AMINO-8-OXO-3-OXA-1-AZABICYCLO- (4.2.0) OCTANE-2-CARBOXYLIC ACID DERIVATIVES
FR2369259A1 (en) 3,3-DICHLORO-2-AZETIDINONE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY
FR2366276A1 (en) AZA-13 PROSTAGLANDINS
FR2358391A1 (en) PROSTAGLANDIN-ANALOGUE CYCLOHEXANE DERIVATIVES
MX4161E (en) PROCEDURE FOR THE PREPARATION OF AMINO-ALCOXI-4 (2H) -PYRANONE-2,3-CONDENSATED SUBSTITUTES-5,62
FR2357517A1 (en) PROCESS FOR THE PRODUCTION OF HALOGENOPHENOLS
FR2359131A1 (en) THIAZOLA-BASED CARDIOVASCULAR AGENTS
FR2367742A1 (en) A-THIO-ALKANOIC DERIVATIVES, THEIR PREPARATION AND USE
FR2364892A1 (en) DI (P-AMINOCYCLOHEXYL) METHANE BIS-BENZALDIMINE ISOMERS
FR2389597A1 (en)
FR2372190A1 (en) ORGANIC SILICON COMPOUNDS CONTAINING AT LEAST ONE RADICAL ALCENYLOXY AND THERMOSETTING COMPOSITIONS CONTAINING THEM
FR2387215A1 (en) 4-ALCOYLTHIO-2-TRIFLUOROMETHYLALCANESULFONANILIDES AND THEIR DERIVATIVES
FR2430937A1 (en) TRIIODO-BENZONITRILES AND DIAGNOSTIC AGENTS CONTAINING SAME
FR2359828A1 (en) 1-LOWER ALKYL-4,5-DIHYDRO-5-PHENYL-2-ALCOXY LOWER CARBONYLAMINO-IMIDAZOLES AND THEIR SUBSTITUTED PHENYL DERIVATIVES
FR2359838A1 (en) GUANIDINS, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
FR2375188A1 (en) FOR: NITRO-AMINES FOR USE AS DIZOTATION COMPONENTS
FR2367767A1 (en) NEW RIFAMYCIN COMPOUNDS
FR2421934A1 (en) SILICY NITERS COLORANTS
FR2377406A1 (en) TETRATHIAPENTALENE AND TETRASELENAPENTALENE COMPOUNDS

Legal Events

Date Code Title Description
ST Notification of lapse