FI20002525A0 - Tulehduksenvastaisia aineita - Google Patents

Tulehduksenvastaisia aineita

Info

Publication number
FI20002525A0
FI20002525A0 FI20002525A FI20002525A FI20002525A0 FI 20002525 A0 FI20002525 A0 FI 20002525A0 FI 20002525 A FI20002525 A FI 20002525A FI 20002525 A FI20002525 A FI 20002525A FI 20002525 A0 FI20002525 A0 FI 20002525A0
Authority
FI
Finland
Prior art keywords
inflammatory substances
inflammation
prevention
treatment
general formula
Prior art date
Application number
FI20002525A
Other languages
English (en)
Swedish (sv)
Other versions
FI20002525A (fi
Inventor
Aino Pippuri
Heimo Haikala
Erkki Nissinen
Kari Loennberg
Minja Hyttilae-Hopponen
Minna Ruotsalainen
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI20002525A priority Critical patent/FI20002525A/fi
Publication of FI20002525A0 publication Critical patent/FI20002525A0/fi
Priority to US10/416,713 priority patent/US6878702B2/en
Priority to ES01996384T priority patent/ES2240564T3/es
Priority to JP2002542398A priority patent/JP4309652B2/ja
Priority to SI200130371T priority patent/SI1341539T1/xx
Priority to PT01996384T priority patent/PT1341539E/pt
Priority to DK01996384T priority patent/DK1341539T3/da
Priority to CA2429109A priority patent/CA2429109C/en
Priority to AU2002223708A priority patent/AU2002223708A1/en
Priority to EP01996384A priority patent/EP1341539B1/en
Priority to PCT/FI2001/001000 priority patent/WO2002040025A1/en
Priority to AT01996384T priority patent/ATE294581T1/de
Priority to DE60110628T priority patent/DE60110628T2/de
Publication of FI20002525A publication Critical patent/FI20002525A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
FI20002525A 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita FI20002525A (fi)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita
DE60110628T DE60110628T2 (de) 2000-11-17 2001-11-16 Antiphlogistische mittel
DK01996384T DK1341539T3 (da) 2000-11-17 2001-11-16 Antiinflammatoriske midler
ES01996384T ES2240564T3 (es) 2000-11-17 2001-11-16 Agentes antinflamatorios.
JP2002542398A JP4309652B2 (ja) 2000-11-17 2001-11-16 抗炎症剤
SI200130371T SI1341539T1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
PT01996384T PT1341539E (pt) 2000-11-17 2001-11-16 Agentes anti-inflamatorios
US10/416,713 US6878702B2 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
CA2429109A CA2429109C (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
AU2002223708A AU2002223708A1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
EP01996384A EP1341539B1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
PCT/FI2001/001000 WO2002040025A1 (en) 2000-11-17 2001-11-16 Anti-inflammatory agents
AT01996384T ATE294581T1 (de) 2000-11-17 2001-11-16 Antiphlogistische mittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita

Publications (2)

Publication Number Publication Date
FI20002525A0 true FI20002525A0 (fi) 2000-11-17
FI20002525A FI20002525A (fi) 2002-05-18

Family

ID=8559519

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20002525A FI20002525A (fi) 2000-11-17 2000-11-17 Tulehduksenvastaisia aineita

Country Status (11)

Country Link
US (1) US6878702B2 (fi)
EP (1) EP1341539B1 (fi)
JP (1) JP4309652B2 (fi)
AT (1) ATE294581T1 (fi)
AU (1) AU2002223708A1 (fi)
CA (1) CA2429109C (fi)
DE (1) DE60110628T2 (fi)
ES (1) ES2240564T3 (fi)
FI (1) FI20002525A (fi)
PT (1) PT1341539E (fi)
WO (1) WO2002040025A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1612204A4 (en) * 2003-03-31 2007-04-11 Daiichi Seiyaku Co HYDRAZONE DERIVATIVE
DE10337904A1 (de) * 2003-08-18 2005-03-24 Universität Duisburg-Essen Substanzen für die Apoptoseregulation, insbesondere Apoptosestimulation
PT2203439E (pt) 2007-09-14 2011-02-11 Ortho Mcneil Janssen Pharm 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas
AU2020408323A1 (en) 2019-12-16 2022-08-11 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HF-pEF)
CN112500353B (zh) * 2020-12-08 2022-11-25 北京晨光同创医药研究院有限公司 一种左西孟旦的前药化合物、制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
US6183948B1 (en) * 1998-04-15 2001-02-06 Johns Hopkins University Methods to identify compounds affecting mitochondria

Also Published As

Publication number Publication date
JP4309652B2 (ja) 2009-08-05
WO2002040025A1 (en) 2002-05-23
ATE294581T1 (de) 2005-05-15
CA2429109A1 (en) 2002-05-23
EP1341539A1 (en) 2003-09-10
DE60110628T2 (de) 2006-01-19
AU2002223708A1 (en) 2002-05-27
FI20002525A (fi) 2002-05-18
US20040029870A1 (en) 2004-02-12
US6878702B2 (en) 2005-04-12
JP2004520278A (ja) 2004-07-08
DE60110628D1 (de) 2005-06-09
CA2429109C (en) 2010-02-16
EP1341539B1 (en) 2005-05-04
ES2240564T3 (es) 2005-10-16
PT1341539E (pt) 2005-07-29

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