ES390598A1 - Production of 22substitutedd 44aminoo6*7*88 trialkoxyquinazoline - Google Patents

Production of 22substitutedd 44aminoo6*7*88 trialkoxyquinazoline

Info

Publication number
ES390598A1
ES390598A1 ES390598A ES390598A ES390598A1 ES 390598 A1 ES390598 A1 ES 390598A1 ES 390598 A ES390598 A ES 390598A ES 390598 A ES390598 A ES 390598A ES 390598 A1 ES390598 A1 ES 390598A1
Authority
ES
Spain
Prior art keywords
formula
carbon atoms
amino
trialkoxyquinazoline
hydroxyethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES390598A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES390598A1 publication Critical patent/ES390598A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A process for preparing substituted 4-amino-6,7,8-trialkoxyquinazolines in the 2-position, of the formula: ** (see formula) ** And their salts by addition of acid, wherein r'is methyl or ethyl; and z is monoalkohilamino or dialcohilamino each having up to 3 carbon atoms in the alkyl moiety; mono- (beta-hydroxyethyl) -amino and di- (beta-hydroxyethyl) -amino, pyrrolidino, piperidino, homopiperidino or N-substituted-piperazino of the formula ** (see formula) ** Wherein r is alkoxy having from 1 to 6 carbon atoms, alkenyloxy having up to 5 carbon atoms, and hydroxyalkoxy having from 2 to 6 carbon atoms, alkyl having from 1 to 6 carbon atoms, phenyl, naphthyl, furyl or thienyl, characterized by reacting a 2-halo-4-amino-6,7,8-trialkoxyquinazoline of the formula ** (see formula) ** Wherein r'is as defined above and x is chlorine or bromine, with an amine of the formula Zh Where z is as defined above. (Machine-translation by Google Translate, not legally binding)
ES390598A 1970-05-21 1971-04-26 Production of 22substitutedd 44aminoo6*7*88 trialkoxyquinazoline Expired ES390598A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3954170A 1970-05-21 1970-05-21

Publications (1)

Publication Number Publication Date
ES390598A1 true ES390598A1 (en) 1973-06-16

Family

ID=21906027

Family Applications (1)

Application Number Title Priority Date Filing Date
ES390598A Expired ES390598A1 (en) 1970-05-21 1971-04-26 Production of 22substitutedd 44aminoo6*7*88 trialkoxyquinazoline

Country Status (5)

Country Link
JP (2) JPS5440553B1 (en)
ES (1) ES390598A1 (en)
FI (1) FI57403C (en)
PH (2) PH9305A (en)
ZA (1) ZA712828B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995032714A1 (en) * 1994-05-31 1995-12-07 Tokyo Tanabe Company Limited Arteriosclerosis depressant

Also Published As

Publication number Publication date
FI57403C (en) 1980-08-11
ZA712828B (en) 1972-01-26
FI57403B (en) 1980-04-30
JPS5439387B2 (en) 1979-11-27
JPS5440553B1 (en) 1979-12-04
JPS5436284A (en) 1979-03-16
PH11322A (en) 1977-11-02
PH9305A (en) 1975-08-18

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