EP1208101A4 - Vitronectin receptor antagonists useful for the treatment of strokes - Google Patents

Vitronectin receptor antagonists useful for the treatment of strokes

Info

Publication number: EP1208101A4
Authority: EP; European Patent Office
Prior art keywords: strokes; treatment; receptor antagonists; vitronectin receptor; antagonists useful
Prior art date: 1999-08-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00952558A

Other languages

German (de)

French (fr)

Other versions

EP1208101A1 (en

Inventor

Frank C Barone

Tian-Li Yue

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-06

Filing date

2000-08-04

Publication date

2003-03-19

2000-08-04 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

2002-05-29 Publication of EP1208101A1 publication Critical patent/EP1208101A1/en

2003-03-19 Publication of EP1208101A4 publication Critical patent/EP1208101A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

EP00952558A 1999-08-06 2000-08-04 Vitronectin receptor antagonists useful for the treatment of strokes Withdrawn EP1208101A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US14756799P	1999-08-06	1999-08-06
US147567P		1999-08-06
PCT/US2000/021433 WO2001010867A1 (en)	1999-08-06	2000-08-04	Vitronectin receptor antagonists useful for the treatment of strokes

Publications (2)

Publication Number	Publication Date
EP1208101A1 EP1208101A1 (en)	2002-05-29
EP1208101A4 true EP1208101A4 (en)	2003-03-19

Family

ID=22522092

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00952558A Withdrawn EP1208101A4 (en)	1999-08-06	2000-08-04	Vitronectin receptor antagonists useful for the treatment of strokes

Country Status (4)

Country	Link
EP (1)	EP1208101A4 (en)
JP (1)	JP2003506452A (en)
AU (1)	AU6523200A (en)
WO (1)	WO2001010867A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ20011872A3 (en)	1999-09-29	2002-03-13	Ortho-Mcneil Pharmaceutical, Inc.	Isonipecotamides for the treatment of integrin-mediated disorders
EP1389205B1 (en)	2001-04-09	2005-12-21	Ortho-McNeil Pharmaceutical Research Inc.	Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders
CN100560131C (en)	2001-10-22	2009-11-18	斯克里普斯研究学院	Antibody targeting compounds
EP2395992A2 (en)	2009-02-10	2011-12-21	The Scripps Research Institute	Chemically programmed vaccination

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996006087A1 (en) *	1994-08-22	1996-02-29	Smithkline Beecham Corporation	Bicyclic compounds
WO1997001540A1 (en) *	1995-06-29	1997-01-16	Smithkline Beecham Corporation	Integrin receptor antagonists
WO1997024119A1 (en) *	1995-12-29	1997-07-10	Smithkline Beecham Corporation	Vitronectin receptor antagonists
WO1998014192A1 (en) *	1996-10-02	1998-04-09	Smithkline Beecham Corporation	Vitronectin receptor antagonists
WO1999006049A1 (en) *	1997-08-04	1999-02-11	Smithkline Beecham Corporation	Integrin receptor antagonists
WO1999011626A1 (en) *	1997-09-04	1999-03-11	Smithkline Beecham Corporation	Integrin receptor antagonists

2000
- 2000-08-04 EP EP00952558A patent/EP1208101A4/en not_active Withdrawn
- 2000-08-04 JP JP2001515676A patent/JP2003506452A/en not_active Withdrawn
- 2000-08-04 WO PCT/US2000/021433 patent/WO2001010867A1/en not_active Application Discontinuation
- 2000-08-04 AU AU65232/00A patent/AU6523200A/en not_active Abandoned

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996006087A1 (en) *	1994-08-22	1996-02-29	Smithkline Beecham Corporation	Bicyclic compounds
WO1997001540A1 (en) *	1995-06-29	1997-01-16	Smithkline Beecham Corporation	Integrin receptor antagonists
WO1997024119A1 (en) *	1995-12-29	1997-07-10	Smithkline Beecham Corporation	Vitronectin receptor antagonists
WO1998014192A1 (en) *	1996-10-02	1998-04-09	Smithkline Beecham Corporation	Vitronectin receptor antagonists
WO1999006049A1 (en) *	1997-08-04	1999-02-11	Smithkline Beecham Corporation	Integrin receptor antagonists
WO1999011626A1 (en) *	1997-09-04	1999-03-11	Smithkline Beecham Corporation	Integrin receptor antagonists

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ELLISON J A ET AL: "OSTEOPONTIN AND ITS INTEGRIN RECEPTOR ALPHAVBETA3 ARE UPREGULATED DURING FORMATION OF THE GLIAL SCAR AFTER FOCAL STROKE", STROKE, AMERICAN HEART ASSOCIATION, DALLAS TX, US, vol. 29, no. 8, August 1998 (1998-08-01), pages 1698 - 1706, XP001029459, ISSN: 0039-2499 *
See also references of WO0110867A1 *

Also Published As

Publication number	Publication date
WO2001010867A1 (en)	2001-02-15
JP2003506452A (en)	2003-02-18
EP1208101A1 (en)	2002-05-29
AU6523200A (en)	2001-03-05

Legal Events

Date	Code	Title	Description
2002-04-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2002-05-29	17P	Request for examination filed	Effective date: 20020215
2002-05-29	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-05-29	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2003-03-19	A4	Supplementary search report drawn up and despatched	Effective date: 20030130
2003-03-19	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 07D 487/00 A Ipc: 7C 07D 417/12 B Ipc: 7C 07D 413/12 B Ipc: 7A 61K 31/47 B Ipc: 7C 07D 401/12 B Ipc: 7A 61P 9/00 B Ipc: 7A 61K 31/44 B
2003-09-05	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2003-10-22	18D	Application deemed to be withdrawn	Effective date: 20030416

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IL130760A0 (en)	2001-01-28	Vitronectin receptor antagonists
EP1229910A4 (en)	2003-10-01	Integrin receptor antagonists
EP1194151A4 (en)	2003-01-15	Integrin receptor antagonists
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SI1379647T1 (en)	2013-08-30	Antagonist antibodies of a mammalian cytokine or its receptor for the treatment of allergy
PL342881A1 (en)	2001-07-16	Vitronectin receptor antagonists
PL352056A1 (en)	2003-07-28	Antagonists of bradykinin receptor
EP1025090A4 (en)	2000-11-08	Vitronectin receptor antagonists
AU2003267088A8 (en)	2004-04-30	Chemokine receptor antagonists as therapeutic agents
IL148043A0 (en)	2002-09-12	Novel integrin receptor antagonists
GC0000203A (en)	2006-03-29	Vitronectin receptor antagonists
EP1208101A4 (en)	2003-03-19	Vitronectin receptor antagonists useful for the treatment of strokes
IL146146A0 (en)	2002-07-25	Integrin receptor antagonists
PL346157A1 (en)	2002-01-28	Vitronectin receptor antagonists
PL352222A1 (en)	2003-08-11	Antagonists of the il-8 receptor
AU2003245995A8 (en)	2004-01-19	Use of gaba-c receptor antagonists for the treatment of myopia
GB9815803D0 (en)	1998-09-16	Vitronectin receptor antagonists
GB9812686D0 (en)	1998-08-12	Vitronectin receptor antagonists
GB9807382D0 (en)	1998-06-03	Vitronectin receptor antagonists
GB9810182D0 (en)	1998-07-08	Vitronectin receptor antagonists
DK1218005T3 (en)	2005-04-11	Vitronectin receptor antagonists
SI1187592T1 (en)	2007-12-31	Alpha v integrin receptor antagonists