EP0946178A4 - Kombinationstherapie zur verminderung der mit herz-kreislauferkrankungen einhergergenden risiken - Google Patents
Kombinationstherapie zur verminderung der mit herz-kreislauferkrankungen einhergergenden risikenInfo
- Publication number
- EP0946178A4 EP0946178A4 EP97941644A EP97941644A EP0946178A4 EP 0946178 A4 EP0946178 A4 EP 0946178A4 EP 97941644 A EP97941644 A EP 97941644A EP 97941644 A EP97941644 A EP 97941644A EP 0946178 A4 EP0946178 A4 EP 0946178A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- reducing
- combination therapy
- cardiovascular disease
- risks associated
- risks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2658196P | 1996-09-18 | 1996-09-18 | |
US26581P | 1996-09-18 | ||
GBGB9621970.4A GB9621970D0 (en) | 1996-10-22 | 1996-10-22 | Combination therapy for reducing the risks associated with cardiovascular disease |
GB9621970 | 1996-10-22 | ||
PCT/US1997/016388 WO1998011896A1 (en) | 1996-09-18 | 1997-09-15 | Combination therapy for reducing the risks associated with cardiovascular disease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0946178A1 EP0946178A1 (de) | 1999-10-06 |
EP0946178A4 true EP0946178A4 (de) | 2003-05-07 |
Family
ID=26310268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97941644A Withdrawn EP0946178A4 (de) | 1996-09-18 | 1997-09-15 | Kombinationstherapie zur verminderung der mit herz-kreislauferkrankungen einhergergenden risiken |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0946178A4 (de) |
JP (1) | JP2001500875A (de) |
AU (1) | AU723315B2 (de) |
CA (1) | CA2265827A1 (de) |
WO (1) | WO1998011896A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6235311B1 (en) | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
WO1999065500A1 (en) | 1998-06-17 | 1999-12-23 | Bristol-Myers Squibb Company | Preventing cerebral infarction through administration of adp-receptor antiplatelet and antihypertensive drugs in combination |
CA2338878A1 (en) * | 1998-08-13 | 2000-02-24 | Merck & Co., Inc. | Integrin receptor antagonists |
SE9802973D0 (sv) * | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
US6972296B2 (en) | 1999-05-07 | 2005-12-06 | Encysive Pharmaceuticals Inc. | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors |
RO122246B1 (ro) * | 1999-05-07 | 2009-03-30 | Texas Biotechnology Corporation | Derivaţi de acid propionic ce inhibă legarea integrinelor de receptorii acestora, compoziţie farmaceutică ce îi conţine şi utilizare |
WO2001021259A2 (en) * | 1999-09-21 | 2001-03-29 | Emory University | Use and compositions for treating platelet-related disorders using anagrelide |
AU4671101A (en) * | 2000-04-10 | 2001-10-23 | Malcolm R. Law | Formulation for the prevention of cardiovascular disease |
GB2361185A (en) * | 2000-04-10 | 2001-10-17 | Nicholas J Wald | Pharmaceutical formulation for the prevention of cardiovascular disease |
WO2002034248A2 (en) * | 2000-10-20 | 2002-05-02 | Boehringer Ingelheim Pharmaceuticals, Inc. | METHOD FOR INCREASING TISSUE PERFUSION BY CO-ADMINISTRATION OF AN AGENT THAT INCREASES cGMP SYNTHESIS AND AN AGENT THAT INHIBITS cGMP DEGRADATION |
DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
WO2004080488A2 (de) * | 2003-03-10 | 2004-09-23 | Bayer Healthcare Ag | Kombinationspräparate von acetylsalicylsäure mit einem hmg-coa-reduktase |
GB0306615D0 (en) * | 2003-03-22 | 2003-04-30 | Astrazeneca Ab | New use |
GB0307715D0 (en) | 2003-04-03 | 2003-05-07 | Ethicon Endo Surgery Inc | Guide wire structure for insertion into an internal space |
US8070693B2 (en) | 2004-09-30 | 2011-12-06 | Cook Medical Technologies Llc | Articulating steerable wire guide |
US7598233B2 (en) * | 2005-03-28 | 2009-10-06 | Kowa Co., Ltd. | Method for treating thrombosis |
KR101299320B1 (ko) | 2005-09-15 | 2013-09-03 | 오츠카 세이야쿠 가부시키가이샤 | 초과산화물 억제제 효과를 갖는 프로부콜 및테트라졸릴알콕시-디히드로카르보스티릴 유도체를 함유하는조합 약물 |
US8715205B2 (en) | 2006-08-25 | 2014-05-06 | Cook Medical Tecnologies Llc | Loop tip wire guide |
GB2460915B (en) | 2008-06-16 | 2011-05-25 | Biovascular Inc | Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor |
LV14963B (lv) | 2013-06-28 | 2015-10-20 | Tetra, Sia | Endoteliālās disfunkcijas korektors |
CN107530168B (zh) | 2015-05-01 | 2020-06-09 | 耶拿阀门科技股份有限公司 | 在心脏瓣膜替换中具有降低的起搏器比例的装置和方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5281585A (en) * | 1991-05-07 | 1994-01-25 | Merck & Co., Inc. | Fibrinogen receptor antagonists for inhibiting aggregation of blood platelets |
US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
WO1997038694A1 (en) * | 1996-04-17 | 1997-10-23 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardiovascular disease |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5140012A (en) * | 1990-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Method for preventing onset of restenosis after angioplasty employing pravastatin |
-
1997
- 1997-09-15 JP JP10514815A patent/JP2001500875A/ja not_active Ceased
- 1997-09-15 CA CA002265827A patent/CA2265827A1/en not_active Abandoned
- 1997-09-15 AU AU43508/97A patent/AU723315B2/en not_active Ceased
- 1997-09-15 WO PCT/US1997/016388 patent/WO1998011896A1/en not_active Application Discontinuation
- 1997-09-15 EP EP97941644A patent/EP0946178A4/de not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
US5281585A (en) * | 1991-05-07 | 1994-01-25 | Merck & Co., Inc. | Fibrinogen receptor antagonists for inhibiting aggregation of blood platelets |
WO1997038694A1 (en) * | 1996-04-17 | 1997-10-23 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardiovascular disease |
Non-Patent Citations (7)
Title |
---|
ARRIGONI-MARTELLI E: "FIRST EUROPEAN CONGRESS OF PHARMACOLOGY", DRUGS OF TODAY / MEDICAMENTOS DE ACTUALIDAD, J.R. PROUS SS.A. INTERNATIONAL PUBLISHERS, ES, vol. 31, no. 8, December 1995 (1995-12-01), pages 635 - 637, XP001061459, ISSN: 0025-7656 * |
CASTAIGNE A ET AL: "TRAITEMENT MEDICAL DES PATIENTS AYANT UN ANGOR STABLE", REVUE DU PRATICIEN, J.B. BAILLERE, PARIS, FR, vol. 45, no. 17, 1975, pages 2161 - 2167, XP001061466, ISSN: 0035-2640 * |
MALYSZKO JOLANTA ET AL: "Effects of short-term treatment with mevalotin on platelet aggregation, fibrinolysis, peripheral serotonergic system and serum lipids in Japanese monkeys.", THROMBOSIS RESEARCH, vol. 81, no. 3, 1996, pages 397 - 402, XP002233543, ISSN: 0049-3848 * |
NOTARBARTOLO A ET AL: "INHIBITION OF THROMBOXANE BIOSYNTHESIS AND PLATELET FUNCTION BY SIMVASTATIN IN TYPE IIA HYPERCHOLESTEROLEMIA", ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, XX, XX, vol. 15, no. 2, February 1995 (1995-02-01), pages 247 - 251, XP001037365, ISSN: 1079-5642 * |
See also references of WO9811896A1 * |
TANVEER RAB S ET AL: "CORONARY ANEURYSMS AFTER STENT PLACEMENT: A SUGGESTION OF ALTERED VESSEL WALL HEALING IN THE PRESENCE OF ANTI-INFLAMMATORY AGENTS", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, XX, XX, vol. 18, no. 6, 15 November 1991 (1991-11-15), pages 1524 - 1528, XP001083633, ISSN: 0735-1097 * |
ZHANG L-H ET AL: "THE CHIRAL SPECIFIC SYNTHESIS OF DMP 754, A PLATELET GP IIB/IIIA ANTAGONIST", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 37, no. 26, 1996, pages 4455 - 4458, XP002071215, ISSN: 0040-4039 * |
Also Published As
Publication number | Publication date |
---|---|
AU4350897A (en) | 1998-04-14 |
WO1998011896A1 (en) | 1998-03-26 |
EP0946178A1 (de) | 1999-10-06 |
JP2001500875A (ja) | 2001-01-23 |
CA2265827A1 (en) | 1998-03-26 |
AU723315B2 (en) | 2000-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990419 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030326 |
|
17Q | First examination report despatched |
Effective date: 20040310 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20050825 |