EP0616612A4 - Nuclease stable and binding competent oligomers and methods for their use. - Google Patents
Nuclease stable and binding competent oligomers and methods for their use.Info
- Publication number
- EP0616612A4 EP0616612A4 EP93900169A EP93900169A EP0616612A4 EP 0616612 A4 EP0616612 A4 EP 0616612A4 EP 93900169 A EP93900169 A EP 93900169A EP 93900169 A EP93900169 A EP 93900169A EP 0616612 A4 EP0616612 A4 EP 0616612A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- binding competent
- nuclease stable
- oligomers
- competent oligomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80671091A | 1991-12-12 | 1991-12-12 | |
US806710 | 1991-12-12 | ||
PCT/US1992/010793 WO1993012135A1 (en) | 1991-12-12 | 1992-12-11 | Nuclease stable and binding competent oligomers and methods for their use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0616612A1 EP0616612A1 (en) | 1994-09-28 |
EP0616612A4 true EP0616612A4 (en) | 1995-01-11 |
Family
ID=25194664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93900169A Withdrawn EP0616612A4 (en) | 1991-12-12 | 1992-12-11 | Nuclease stable and binding competent oligomers and methods for their use. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0616612A4 (en) |
AU (1) | AU3250093A (en) |
WO (1) | WO1993012135A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378825A (en) * | 1990-07-27 | 1995-01-03 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogs |
US6251939B1 (en) | 1995-06-07 | 2001-06-26 | Promega Biosciences, Inc. | Carbamate-based cationic lipids |
US6274313B1 (en) | 1996-03-21 | 2001-08-14 | Pioneer-Hybrid International, Inc. | Oligonucleotides with cationic phosphoramidate internucleoside linkages and methods of use |
US6331617B1 (en) | 1996-03-21 | 2001-12-18 | University Of Iowa Research Foundation | Positively charged oligonucleotides as regulators of gene expression |
US8785409B2 (en) | 2007-01-30 | 2014-07-22 | Geron Corporation | Compounds having anti-adhesive effects on cancer cells |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US327501A (en) | 1885-09-29 | Wet-grinding mill | ||
US3282920A (en) * | 1963-03-19 | 1966-11-01 | Asahi Chemical Ind | Method for producing 5'-nucleotides |
US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
DE3329892A1 (en) | 1983-08-18 | 1985-03-07 | Köster, Hubert, Prof. Dr., 2000 Hamburg | METHOD FOR PRODUCING OLIGONUCLEOTIDES |
JP2528107B2 (en) | 1985-03-15 | 1996-08-28 | サマ−トン,ジエ−ムス | Reagents and methods for measuring polynucleotides |
US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
US4959463A (en) | 1985-10-15 | 1990-09-25 | Genentech, Inc. | Intermediates |
JPH05500799A (en) | 1989-06-05 | 1993-02-18 | ギリアド サイエンシス,インコーポレイテッド | Exonuclease-resistant oligonucleotide and method for its preparation |
US5264562A (en) | 1989-10-24 | 1993-11-23 | Gilead Sciences, Inc. | Oligonucleotide analogs with novel linkages |
US5495009A (en) | 1989-10-24 | 1996-02-27 | Gilead Sciences, Inc. | Oligonucleotide analogs containing thioformacetal linkages |
US5177198A (en) | 1989-11-30 | 1993-01-05 | University Of N.C. At Chapel Hill | Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates |
US5470967A (en) | 1990-04-10 | 1995-11-28 | The Dupont Merck Pharmaceutical Company | Oligonucleotide analogs with sulfamate linkages |
EP0531436A4 (en) | 1990-05-25 | 1993-06-16 | Gilead Sciences, Inc. | Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna |
ATE154246T1 (en) | 1990-07-27 | 1997-06-15 | Isis Pharmaceuticals Inc | NUCLEASE RESISTANT PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECTE AND MODULATE GENE EXPRESSION |
CA2092002A1 (en) | 1990-09-20 | 1992-03-21 | Mark Matteucci | Modified internucleoside linkages |
DK0592434T3 (en) | 1990-10-26 | 1999-06-21 | Genta Inc | Improved method for the synthesis of oligomers |
WO1992009705A1 (en) | 1990-11-23 | 1992-06-11 | Gilead Sciences, Inc. | Triplex-forming oligomers containing modified bases |
AU1435492A (en) | 1991-02-21 | 1992-09-15 | Gilead Sciences, Inc. | Aptamer specific for biomolecules and method of making |
AU1456092A (en) | 1991-02-21 | 1992-09-15 | Gilead Sciences, Inc. | Aptamers specific for thrombin and methods of use |
DK51092D0 (en) | 1991-05-24 | 1992-04-15 | Ole Buchardt | OLIGONUCLEOTIDE ANALOGUE DESCRIBED BY PEN, MONOMERIC SYNTHONES AND PROCEDURES FOR PREPARING THEREOF, AND APPLICATIONS THEREOF |
WO1993009127A1 (en) | 1991-11-07 | 1993-05-13 | Gilead Sciences, Inc. | Enhanced triple-helix formation directed by oligonucleotides composed of 2'-deoxy-7-deazaxanthosine and 2'-deoxy-7-deazaguanosine and related analogs |
WO1993024507A1 (en) | 1992-05-28 | 1993-12-09 | Gilead Sciences, Inc. | Conformationally restrained oligomers containing amide or carbamate linkages for sequence-specific binding |
US5817781A (en) | 1992-06-01 | 1998-10-06 | Gilead Sciences, Inc. | Modified internucleoside linkages (II) |
TWI515034B (en) | 2013-09-16 | 2016-01-01 | cheng wei Liu | Magic blocks of dynamic fault-tolerant structures |
US10368098B2 (en) | 2014-06-20 | 2019-07-30 | Samsung Electronics Co., Ltd. | Method and device for transmitting prediction mode of depth image for interlayer video encoding and decoding |
US10881198B1 (en) | 2020-03-09 | 2021-01-05 | You Yun Ren Jia (Shenzhen) Service Co., Ltd. | Sink shelf organizer |
-
1992
- 1992-12-11 AU AU32500/93A patent/AU3250093A/en not_active Abandoned
- 1992-12-11 WO PCT/US1992/010793 patent/WO1993012135A1/en not_active Application Discontinuation
- 1992-12-11 EP EP93900169A patent/EP0616612A4/en not_active Withdrawn
Non-Patent Citations (3)
Title |
---|
PRITCHARD A.E.: "Nucleic Acids Symposium Series No. 10", 1981, INFORMATION RETRIEVAL LIMITED, LONDON GB * |
See also references of WO9312135A1 * |
TANIMURA H. ET AL, CHEMISTRY LETTERS, 1987, TOKYO JP, pages 1057 - 1060 * |
Also Published As
Publication number | Publication date |
---|---|
EP0616612A1 (en) | 1994-09-28 |
AU3250093A (en) | 1993-07-19 |
WO1993012135A1 (en) | 1993-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19940622 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 19941124 |
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AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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RHK1 | Main classification (correction) |
Ipc: C07H 21/00 |
|
17Q | First examination report despatched |
Effective date: 19961018 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
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GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
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GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
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GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 19990810 |