DK0760819T3 - Tricykliske dicarbonylderivater - Google Patents

Tricykliske dicarbonylderivater

Info

Publication number: DK0760819T3
Authority: DK; Denmark
Prior art keywords: lower alkyl; pct; disease; amino; signify
Prior art date: 1994-05-24

Application number

DK95920816T

Other languages

English (en)

Inventor

Bernd Buettelmann

Thierry Godel

Laurence Gross

Neidhart Marie-Paule Heitz

Claus Riemer

Rene Wyler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-24

Filing date

1995-05-16

Publication date

2000-10-09

1995-05-16 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2000-10-09 Application granted granted Critical

2000-10-09 Publication of DK0760819T3 publication Critical patent/DK0760819T3/da

Links

125000004989 dicarbonyl group Chemical group 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 8
125000004429 atom Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
230000002265 prevention Effects 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
206010003805 Autism Diseases 0.000 abstract 1
208000020706 Autistic disease Diseases 0.000 abstract 1
208000023275 Autoimmune disease Diseases 0.000 abstract 1
206010010904 Convulsion Diseases 0.000 abstract 1
208000020401 Depressive disease Diseases 0.000 abstract 1
208000023105 Huntington disease Diseases 0.000 abstract 1
208000013016 Hypoglycemia Diseases 0.000 abstract 1
206010021143 Hypoxia Diseases 0.000 abstract 1
208000036626 Mental retardation Diseases 0.000 abstract 1
208000001089 Multiple system atrophy Diseases 0.000 abstract 1
208000008238 Muscle Spasticity Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
208000018737 Parkinson disease Diseases 0.000 abstract 1
208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
206010047163 Vasospasm Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 1
230000001580 bacterial effect Effects 0.000 abstract 1
125000002618 bicyclic heterocycle group Chemical group 0.000 abstract 1
230000002490 cerebral effect Effects 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
-1 hydroxy, amino Chemical group 0.000 abstract 1
230000007954 hypoxia Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
230000035987 intoxication Effects 0.000 abstract 1
231100000566 intoxication Toxicity 0.000 abstract 1
208000028867 ischemia Diseases 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
208000031237 olivopontocerebellar atrophy Diseases 0.000 abstract 1
230000036407 pain Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
201000000980 schizophrenia Diseases 0.000 abstract 1
208000018198 spasticity Diseases 0.000 abstract 1
208000020431 spinal cord injury Diseases 0.000 abstract 1
125000005505 thiomorpholino group Chemical group 0.000 abstract 1
230000008733 trauma Effects 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
230000003612 virological effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Toxicology (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK95920816T 1994-05-24 1995-05-16 Tricykliske dicarbonylderivater DK0760819T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH160294		1994-05-24
CH47795		1995-02-17
PCT/EP1995/001856 WO1995032205A1 (en)	1994-05-24	1995-05-16	Tricyclic dicarbonyl derivatives

Publications (1)

Publication Number	Publication Date
DK0760819T3 true DK0760819T3 (da)	2000-10-09

Family

ID=25684688

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95920816T DK0760819T3 (da)	1994-05-24	1995-05-16	Tricykliske dicarbonylderivater

Country Status (16)

Country	Link
US (1)	US5688803A (da)
EP (1)	EP0760819B1 (da)
JP (1)	JP2828506B2 (da)
CN (1)	CN1044245C (da)
AT (1)	ATE194841T1 (da)
AU (1)	AU688515B2 (da)
BR (1)	BR9507672A (da)
CA (1)	CA2189776A1 (da)
DE (1)	DE69518075T2 (da)
DK (1)	DK0760819T3 (da)
ES (1)	ES2149989T3 (da)
GR (1)	GR3034625T3 (da)
NZ (1)	NZ287413A (da)
PT (1)	PT760819E (da)
RU (1)	RU2145606C1 (da)
WO (1)	WO1995032205A1 (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5243049A (en) *	1992-01-22	1993-09-07	Neurogen Corporation	Certain pyrroloquinolinones: a new class of GABA brain receptor ligands
US5955465A (en) *	1996-03-22	1999-09-21	Neurogen Corporation	1,2,4-triazolo 4,3-c!quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones
GB2346883B (en) *	1996-09-02	2001-02-14	Lilly Industries Ltd	GluR5 receptor binding assay
FR2773153A1 (fr) *	1997-12-29	1999-07-02	Rhone Poulenc Agrochimie	Nouveaux composes fongicides
US6972296B2 (en)	1999-05-07	2005-12-06	Encysive Pharmaceuticals Inc.	Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
WO2001046190A1 (fr) *	1999-12-22	2001-06-28	Kyorin Pharmaceutical Co., Ltd.	Composes tricycliques et sels d'addition de ceux-ci
DE10004572A1 (de) *	2000-02-02	2001-08-09	Boehringer Ingelheim Pharma	Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
GB0223730D0 (en) *	2002-10-11	2002-11-20	Novartis Ag	Organic compounds
US7842701B2 (en)	2004-02-19	2010-11-30	Takeda Pharmaceutical Company Limited	Pyrazoloquinolone derivative and use thereof
JO3077B1 (ar) *	2005-07-28	2017-03-15	Janssen Pharmaceutica Nv	مشتقات كوينولين مضادة للبكتيريا
TW200806670A (en) *	2006-04-25	2008-02-01	Merck & Co Inc	Inhibitors of checkpoint kinases
US8139680B2 (en)	2007-01-12	2012-03-20	General Dynamics C4 Systems, Inc.	Signal acquisition methods and apparatus in wireless communication systems
US7907679B2 (en) *	2007-01-12	2011-03-15	General Dynamics C4 Systems, Inc.	Methods and systems for acquiring signals using coherent match filtering
US20080293712A1 (en) *	2007-03-05	2008-11-27	Wyeth	Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof
KR20100036306A (ko) *	2007-06-08	2010-04-07	헬리콘 테라퓨틱스 인코퍼레이티드	치료용 피라졸로나프티리딘 유도체
US8809355B2 (en) *	2008-04-04	2014-08-19	Innovationspatent Sverige Ab	GABAA receptor modulators
DE102008022221A1 (de)	2008-05-06	2009-11-12	Universität des Saarlandes	Inhibitoren der humanen Aldosteronsynthase CYP11B2
US9156836B2 (en)	2008-05-16	2015-10-13	Synta Pharmaceuticals Corp.	Tricyclic triazole compounds that modulate HSP90 activity
EP2303890A4 (en) *	2008-06-19	2012-04-11	Progenics Pharm Inc	INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE
BRPI0922010A2 (pt)	2008-11-14	2015-12-15	Hoffmann La Roche	dervivados de quinazolina como antagonistas receptores de nk3
US8541404B2 (en)	2009-11-09	2013-09-24	Elexopharm Gmbh	Inhibitors of the human aldosterone synthase CYP11B2
US8513421B2 (en)	2010-05-19	2013-08-20	Millennium Pharmaceuticals, Inc.	Substituted hydroxamic acids and uses thereof
WO2013151876A1 (en) *	2012-04-04	2013-10-10	Merck Sharp & Dohme Corp.	Aldosterone synthase inhibitors
BR112015012830B1 (pt)	2012-12-04	2021-01-26	Volvo Truck Corporation	método e sistema para controle de injeção de combustível
CN103073547A (zh) *	2013-02-06	2013-05-01	上海药明康德新药开发有限公司	一种(3aS,9bR)-叔丁基-3,3a,4,5-四氢吡咯[3,4-c]喹啉-2(9bH)酯的合成方法
CA2907971C (en) *	2013-04-05	2020-12-29	Eisai R&D Management Co., Ltd.	Salt of pyrazoloquinoline derivative, and crystal thereof
SG11201507733YA (en)	2013-04-05	2015-10-29	Eisai R&D Man Co Ltd	Pyridinylpyrazoloquinoline compound
CN104447736B (zh) *	2014-10-14	2016-06-08	雅安职业技术学院	一种veranamine的合成方法
AU2018276565A1 (en)	2017-06-01	2019-11-07	Eisai R&D Management Co., Ltd.	Dementia therapeutic agent combining pyrazoloquinoline derivative and donepezil
SG10202113199RA (en)	2017-06-01	2021-12-30	Eisai R&D Man Co Ltd	Dementia therapeutic agent combining pyrazoloquinoline derivative and memantine
RU2019135261A (ru)	2017-06-01	2021-07-09	Эйсай Ар Энд Ди Менеджмент Ко., Лтд.	Фармацевтическая композиция, содержащая ингибитор pde9
BR112019023552A2 (pt)	2017-06-01	2020-06-02	Eisai R&D Management Co., Ltd.	Agente terapêutico para a demência com corpos de lewy contendo derivado de pirazoloquinolina
WO2024012554A1 (zh) *	2022-07-14	2024-01-18	上海日馨医药科技股份有限公司	Tpk激动剂及使用其治疗神经退行性疾病的方法

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IL66835A (en) *	1981-09-24	1988-05-31	Roussel Uclaf	1,4-disubstituted(1,2,4)triazolo(4,3-alpha)quinazolin-5(4h)-one derivatives and their salts,their preparation and pharmaceutical compositions containing them
US4713383A (en) *	1984-10-01	1987-12-15	Ciba-Geigy Corporation	Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
DE69113115T2 (de) *	1990-05-31	1996-06-13	Merck Sharp & Dohme	Dioxo-tetrahydrochinolinderivate.

1995
- 1995-05-16 JP JP7530032A patent/JP2828506B2/ja not_active Expired - Fee Related
- 1995-05-16 CA CA002189776A patent/CA2189776A1/en not_active Abandoned
- 1995-05-16 RU RU96124496/04A patent/RU2145606C1/ru not_active IP Right Cessation
- 1995-05-16 CN CN95193244A patent/CN1044245C/zh not_active Expired - Fee Related
- 1995-05-16 DE DE69518075T patent/DE69518075T2/de not_active Expired - Fee Related
- 1995-05-16 DK DK95920816T patent/DK0760819T3/da active
- 1995-05-16 WO PCT/EP1995/001856 patent/WO1995032205A1/en active IP Right Grant
- 1995-05-16 PT PT95920816T patent/PT760819E/pt unknown
- 1995-05-16 AT AT95920816T patent/ATE194841T1/de not_active IP Right Cessation
- 1995-05-16 ES ES95920816T patent/ES2149989T3/es not_active Expired - Lifetime
- 1995-05-16 EP EP95920816A patent/EP0760819B1/en not_active Expired - Lifetime
- 1995-05-16 BR BR9507672A patent/BR9507672A/pt not_active IP Right Cessation
- 1995-05-16 US US08/737,240 patent/US5688803A/en not_active Expired - Fee Related
- 1995-05-16 AU AU26130/95A patent/AU688515B2/en not_active Ceased
- 1995-05-16 NZ NZ287413A patent/NZ287413A/en unknown
2000
- 2000-10-13 GR GR20000402311T patent/GR3034625T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1995032205A1 (en)	1995-11-30
RU2145606C1 (ru)	2000-02-20
JPH09506634A (ja)	1997-06-30
DE69518075T2 (de)	2001-03-22
ATE194841T1 (de)	2000-08-15
PT760819E (pt)	2000-11-30
AU688515B2 (en)	1998-03-12
BR9507672A (pt)	1997-08-19
CN1149295A (zh)	1997-05-07
DE69518075D1 (de)	2000-08-24
JP2828506B2 (ja)	1998-11-25
ES2149989T3 (es)	2000-11-16
US5688803A (en)	1997-11-18
EP0760819A1 (en)	1997-03-12
CN1044245C (zh)	1999-07-21
NZ287413A (en)	1998-02-26
CA2189776A1 (en)	1995-11-30
AU2613095A (en)	1995-12-18
EP0760819B1 (en)	2000-07-19
GR3034625T3 (en)	2001-01-31

Publication	Publication Date	Title
ATE194841T1 (de)	2000-08-15	Tricyclische dicarbonylderivate
CA2783727A1 (en)	2011-06-23	2-arylimidazole derivatives as pde10a enzyme inhibitors
KR20180095625A (ko)	2018-08-27	신규한 화합물
CN108602818B (zh)	2021-12-21	吡唑稠环类衍生物、其制备方法及其在治疗癌症，炎症和免疫性疾病上的应用
AU695045B2 (en)	1998-08-06	Heteroaromatic oxazole compounds and use thereof
YU27902A (sh)	2004-11-25	Derivati benzodiazepina
PT672042E (pt)	2006-08-31	Derivados de pirimidinoamina farmacologicamente activos e processos para a sua preparacao
CA2386974A1 (en)	2001-04-26	Benzodiazepine derivatives for use in acute or chronic neurological disorders
AU2003284632A1 (en)	2004-06-18	Isoquinoline compounds and medicinal use thereof
DE69222096D1 (de)	1997-10-16	Tetrahydropyrrolo[1,2-a]Pyrazin-4-Spiro-3'-Pyrrolidin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
NZ600365A (en)	2013-10-25	Heteroaromatic aryl triazole derivatives as pde10a enzyme inhibitors
CA2601098A1 (en)	2006-09-28	Dipyrazoles as central nervous system agents
CA2036163C (en)	2001-06-19	Novel beta-lactam compounds and their production
DE69415341D1 (de)	1999-01-28	Kondensierte tricyclische heteroaromatische derivate als liganden des dopamin-rezeptor-subtyps
AU1090888A (en)	1988-08-04	Cinnoline-carboxamides and process for their preparation
BR9509353A (pt)	1997-12-30	Utilzação de diazepino-indolas as respectivas diazepino- indolas e medicamen to
TR199900946T2 (xx)	1999-07-21	2-Metoksifenilpiperazin t�revleri.
JO2307B1 (en)	2005-09-12	Papermidine derivatives
EP1557414A4 (en)	2007-10-31	ISOQUINOLINE COMPOUNDS AND THEIR MEDICINAL USE
BR0213177A (pt)	2004-09-14	Derivados de 5-metóxi-8-aril-[1,2,4]triazolo[1,5-a]piridina
JPWO2002042312A1 (ja)	2004-03-25	新規カルバペネム誘導体
WO2001007023A3 (en)	2001-05-25	Azetidine compounds in cns and eye diseases
IE67525B1 (en)	1996-04-03	Derivatives of Penem
ES2112470T3 (es)	1998-04-01	Derivados de piridazinona, procedimientos de produccion y utilizacion.
WO2001007022A3 (en)	2001-06-14	Azetidine compounds in cns and eye diseases