DE60004850D1 - Verfahren zur herstellung von (r) und (s)-aminocarnitin und deren derivative aus d- und l-aspargin säure - Google Patents
Verfahren zur herstellung von (r) und (s)-aminocarnitin und deren derivative aus d- und l-aspargin säureInfo
- Publication number
- DE60004850D1 DE60004850D1 DE60004850T DE60004850T DE60004850D1 DE 60004850 D1 DE60004850 D1 DE 60004850D1 DE 60004850 T DE60004850 T DE 60004850T DE 60004850 T DE60004850 T DE 60004850T DE 60004850 D1 DE60004850 D1 DE 60004850D1
- Authority
- DE
- Germany
- Prior art keywords
- aminocarnitine
- derivatives
- producing
- asparginic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM990418 | 1999-06-30 | ||
IT1999RM000418A IT1306162B1 (it) | 1999-06-30 | 1999-06-30 | Sintesi di (r) e (s)-amminocarnitina e di suoi derivati a partire daacido d e l-aspartico. |
PCT/IT2000/000258 WO2001002341A1 (en) | 1999-06-30 | 2000-06-23 | Synthesis of (r) and (s)-aminocarnitine and their derivatives starting from d- and l-aspartic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60004850D1 true DE60004850D1 (de) | 2003-10-02 |
DE60004850T2 DE60004850T2 (de) | 2004-05-27 |
Family
ID=11406859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60004850T Expired - Lifetime DE60004850T2 (de) | 1999-06-30 | 2000-06-23 | Verfahren zur herstellung von (r) und (s)-aminocarnitin und deren derivative aus d- und l-aspargin säure |
Country Status (10)
Country | Link |
---|---|
US (1) | US6528684B1 (de) |
EP (1) | EP1194398B1 (de) |
AT (1) | ATE248141T1 (de) |
AU (1) | AU5844800A (de) |
DE (1) | DE60004850T2 (de) |
DK (1) | DK1194398T3 (de) |
ES (1) | ES2204644T3 (de) |
IT (1) | IT1306162B1 (de) |
PT (1) | PT1194398E (de) |
WO (1) | WO2001002341A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
US20030153783A1 (en) * | 1999-06-30 | 2003-08-14 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid |
US6822115B2 (en) * | 1999-06-30 | 2004-11-23 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid |
US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
US8410150B2 (en) * | 2007-03-09 | 2013-04-02 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
CA2694724C (en) * | 2007-08-01 | 2017-09-12 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
IT1261489B (it) * | 1993-07-29 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. |
-
1999
- 1999-06-30 IT IT1999RM000418A patent/IT1306162B1/it active
-
2000
- 2000-06-23 PT PT00944218T patent/PT1194398E/pt unknown
- 2000-06-23 ES ES00944218T patent/ES2204644T3/es not_active Expired - Lifetime
- 2000-06-23 US US10/018,794 patent/US6528684B1/en not_active Expired - Fee Related
- 2000-06-23 DK DK00944218T patent/DK1194398T3/da active
- 2000-06-23 WO PCT/IT2000/000258 patent/WO2001002341A1/en active IP Right Grant
- 2000-06-23 EP EP00944218A patent/EP1194398B1/de not_active Expired - Lifetime
- 2000-06-23 DE DE60004850T patent/DE60004850T2/de not_active Expired - Lifetime
- 2000-06-23 AT AT00944218T patent/ATE248141T1/de not_active IP Right Cessation
- 2000-06-23 AU AU58448/00A patent/AU5844800A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6528684B1 (en) | 2003-03-04 |
ITRM990418A1 (it) | 2000-12-30 |
IT1306162B1 (it) | 2001-05-30 |
PT1194398E (pt) | 2004-01-30 |
WO2001002341A1 (en) | 2001-01-11 |
ITRM990418A0 (it) | 1999-06-30 |
EP1194398A1 (de) | 2002-04-10 |
DE60004850T2 (de) | 2004-05-27 |
AU5844800A (en) | 2001-01-22 |
DK1194398T3 (da) | 2003-12-22 |
ES2204644T3 (es) | 2004-05-01 |
ATE248141T1 (de) | 2003-09-15 |
EP1194398B1 (de) | 2003-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |