DE2832782C2 - Process for the production of bread and baked goods preparations containing pharmaceutical drugs - Google Patents

Process for the production of bread and baked goods preparations containing pharmaceutical drugs

Info

Publication number
DE2832782C2
DE2832782C2 DE19782832782 DE2832782A DE2832782C2 DE 2832782 C2 DE2832782 C2 DE 2832782C2 DE 19782832782 DE19782832782 DE 19782832782 DE 2832782 A DE2832782 A DE 2832782A DE 2832782 C2 DE2832782 C2 DE 2832782C2
Authority
DE
Germany
Prior art keywords
bread
baked goods
containing pharmaceutical
production
pharmaceutical drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19782832782
Other languages
German (de)
Other versions
DE2832782B1 (en
Inventor
Armin 5310 Geilenkirchen Kleinert
Geerd 5372 Schleiden Kleinert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkonat Produkt and Vertrieb 5130 Geilenkirchen GmbH
Original Assignee
Alkonat Produkt and Vertrieb 5130 Geilenkirchen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkonat Produkt and Vertrieb 5130 Geilenkirchen GmbH filed Critical Alkonat Produkt and Vertrieb 5130 Geilenkirchen GmbH
Priority to DE19782832782 priority Critical patent/DE2832782C2/en
Priority to EP79102619A priority patent/EP0008036A1/en
Priority to GB7926111A priority patent/GB2029217A/en
Publication of DE2832782B1 publication Critical patent/DE2832782B1/en
Application granted granted Critical
Publication of DE2832782C2 publication Critical patent/DE2832782C2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/36—Vegetable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Plant Substances (AREA)

Description

Es ist bekannt, Backwaren mit Gewürzen, auch in zerkleinerter Form, zu versetzen, ζ. Β. Kümmelbrot oder Anisplätzchen. Bei Arzneidrogenpräparaten ist diese Zubereitungsform jedoch unbekannt und wird von den Pharmakopöen auch nicht vorgesehen. Im Gegenteil sollen nach herrschender Meinung Galenika die Wirkstoffe in sogenannter therapeutisch wertvoller Form, möglichst befreit von Ballaststoffen, enthalten. Als feste Zubereitungen sind allenfalls Frischpflanzenverreibungen mit Zucker und anderen Trägersubstanzen vorgesehen. Es fehlt jedoch an einem festen Träger, der nicht nur eine zuverlässige Dosierung ermöglicht, sondern auch die perorale Verabreichung erleichtert und vereinfachtIt is known to make baked goods with spices, even in shredded form, to displace, ζ. Β. Caraway bread or aniseed cookies. For medicinal drug preparations is However, this form of preparation is unknown and is not provided for by the pharmacopoeias. On the contrary According to the prevailing opinion, Galenika should make the active ingredients in so-called therapeutically valuable Form, as far as possible free of fiber. Fresh plant triturations are at best as solid preparations provided with sugar and other carriers. However, there is no solid support which not only enables reliable dosing, but also facilitates oral administration and simplified

Überraschenderweise wurde gefunden, daß der normale Backvorgang die Wirkstoffe von Arzneimitleklrogen nicht oder kaum mehr beeinträchtigt als Abkochungen und andere Zubereitungsformen. Auch die anderen Forderungen von J. Pöechi (Arch. Pharm. 285, 40, 1952) werden weitgehend erfüllt. Bei Dauerbackwaren ist insbesondere eine gute Haltbarkeit gegeben.Surprisingly, it has been found that the normal baking process removes the active ingredients of drug leclrogen not or hardly more affected than decoctions and other forms of preparation. Even the other requirements of J. Pöechi (Arch. Pharm. 285, 40, 1952) are largely met. For long-life baked goods in particular, it has a good shelf life.

Darüber hinaus scheint in einigen Fällen eine Aktivierung der Wirkstoffe einzutreten, die möglicherweise auf biologische oder chemische Reaktionen während der Teiglockerung zurückzuführen ist.
ίο Die Erfindung betrifft daher das im Anspruch definierte Verfahren.In addition, in some cases the active ingredients seem to be activated, possibly due to biological or chemical reactions during the dough loosening.
ίο The invention therefore relates to the method defined in the claim.

Die Erfindung ist durch das nachfolgende Beispiel erläutert: Abführkräuter gegen Hartleibigkeit und Stuhlverstopfung (Angaben in Gew.-%): Schlehdorn 10, Holunder 6, Bitterklee 6, Sennesblätter 30, Sennesschoten 25, Fencl.el 4, Kümmel 3, Ginster 10, Stiefmütterchen 6.The invention is illustrated by the following example: Laxative herbs against obesity and Constipation (data in% by weight): blackthorn 10, elderberry 6, bitter clover 6, senna leaves 30, senna pods 25, Fencl.el 4, Caraway 3, Gorse 10, Pansy 6.

Diese Drogen werden getrocknet und feint, gepulvert. Das Pulver wird einer Mehlmischunjj für ein Roggen-Vollkornbrot mit Sauerteiggärung zugesetzt, und das Brot wird in üblicher Weise fertiggestellt. Die Drogenmenge beträgt etwa 20 bis 30 g auf ein Brot von 750 g Gewicht.These drugs are dried and refined, powdered. The powder becomes a flour mix for one Whole grain rye bread with sourdough fermentation is added and the bread is finished in the usual way. the Amount of drug is about 20 to 30 g on a bread of 750 g weight.

Das Brot ist im Geschmack angenehm und hat eine verdauungsregelnde Wirkung, die harmonischer ist als die eines Aufgusses aus den genannten Bestandteilen.The bread has a pleasant taste and has a digestive effect that is more harmonious than that of an infusion from the mentioned ingredients.

Die Brotkrume fördert die Peristaltik; tiefgekühlt ist die Zubereitung lange Zeit haltbar.The bread crumb promotes peristalsis; is frozen the preparation can be kept for a long time.

Die Verwertung der Erfindung kann durch gesetzliehe Bestimmungen beschränkt sein (vgl. § la PatG. Ziffer 1).The exploitation of the invention can be restricted by statutory provisions (cf. § la PatG. Section 1).

Claims (1)

Patentanspruch:Claim: Verfahren zur Herstellung Arzneimitteldrogen enthaltender Brot- und Backwaren, dadurch gekennzeichnet, daß man die Arzneimitteldroge(n) in fein gepulverter Form oder/und als Preßsaft, Destillat bzw Extrakt dosiert in einen Brot- oder Gebäckteig homogen einmischt und diesen in an sich bekannter Weise lockert, teilt, wirkt, formt und ausbäckt.Process for the manufacture of bread and baked goods containing pharmaceutical drugs, thereby characterized in that the drug (s) in finely powdered form and / or as Press juice, distillate or extract dosed homogeneously in a bread or pastry dough and mixed loosens, divides, works, shapes and bakes it in a known manner.
DE19782832782 1978-07-26 1978-07-26 Process for the production of bread and baked goods preparations containing pharmaceutical drugs Expired DE2832782C2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE19782832782 DE2832782C2 (en) 1978-07-26 1978-07-26 Process for the production of bread and baked goods preparations containing pharmaceutical drugs
EP79102619A EP0008036A1 (en) 1978-07-26 1979-07-24 Process of making bread with herbs
GB7926111A GB2029217A (en) 1978-07-26 1979-07-26 Herbal Bakery Products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782832782 DE2832782C2 (en) 1978-07-26 1978-07-26 Process for the production of bread and baked goods preparations containing pharmaceutical drugs

Publications (2)

Publication Number Publication Date
DE2832782B1 DE2832782B1 (en) 1979-08-23
DE2832782C2 true DE2832782C2 (en) 1980-04-30

Family

ID=6045422

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782832782 Expired DE2832782C2 (en) 1978-07-26 1978-07-26 Process for the production of bread and baked goods preparations containing pharmaceutical drugs

Country Status (1)

Country Link
DE (1) DE2832782C2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202006016711U1 (en) * 2006-11-02 2008-03-13 Bäckerei Ralf Edelmann GmbH Baked goods containing L-carnitine, taurine or Egyptian black cumin oil

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK83292D0 (en) * 1992-06-24 1992-06-24 Faellesforeningen For Danmarks BREAD PRODUCT

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202006016711U1 (en) * 2006-11-02 2008-03-13 Bäckerei Ralf Edelmann GmbH Baked goods containing L-carnitine, taurine or Egyptian black cumin oil

Also Published As

Publication number Publication date
DE2832782B1 (en) 1979-08-23

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee