CN1943650B - Rose liquid eye drops - Google Patents
Rose liquid eye drops Download PDFInfo
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- CN1943650B CN1943650B CN200610150185XA CN200610150185A CN1943650B CN 1943650 B CN1943650 B CN 1943650B CN 200610150185X A CN200610150185X A CN 200610150185XA CN 200610150185 A CN200610150185 A CN 200610150185A CN 1943650 B CN1943650 B CN 1943650B
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- water
- rose
- eye drop
- rose water
- distillation
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Abstract
This invention relates to the new applications of the rose water in the preparation of the eye drops. The rose water is prepared by distillation from the mixture of rose and water with ratio of 1:1-10 by weight. Distilling velocity is such that the liquid distilled out per hour amounts to 2-20% of the total volume of water, the distilling time is 30 minutes to10 hours, then stop distilling, keep the distilled liquid stay quite for one hour, then extract the water i.e. rose water out of the distilled liquid. The eye drops with the rose water as the main raw material can effectively remit the eye tiredness, dryness, itching with fine curative effect to the anaphylaxis or inflammation or infection of the eye cornea and conjunctiva but with very light irritation. The eye drops also has the character of high effectiveness, light toxin, less untoward effect. It has broad application prospect.
Description
Technical field
The present invention relates to a kind of eye drop, specifically, is a kind of rose water eye drop.
Technical background
Flos Rosae Rugosae is a kind of common flowers, and all there is plantation all parts of the country.Now, Flos Rosae Rugosae not only is used to view and admire and presenting friends, and its each several part also begins commercial Application.The commercial Application of present Flos Rosae Rugosae mainly contains: A. increases its fragrance as the adjuvant of wine or beverage; B. as the composition of cosmetics or cosmetics, main effect is to preserve moisture and whiten.To the application, do not see its medicinal report as yet.
Summary of the invention
The present inventor is inquiring into and is studying in the process of rose water to the human efficiency, the rose water that discovery is extracted from Flos Rosae Rugosae with steam distillation, be used for eye outward, can alleviate symptoms such as eyes discomfort such as eyestrain, dry and astringent and pruritus effectively, the infection of corneal, conjunctiva allergy or inflammation, cornea and conjunctiva is all effective in cure, and zest is very little.After the present invention is finished in repeated multiple times experiment and research.
Except the new purposes of above-mentioned rose water, another object of the present invention provides a kind of rose water eye drop.
In the present invention, " rose water " is only to refer to utilize the vapor distillation method to process the extract that Flos Rosae Rugosae obtains.Flos Rosae Rugosae is carried out vapor distillation, and its distillate is made up of two parts: the one, and Oleum Rosae Rugosae, the 2nd, rose water, this rose water are exactly " rose water " of indication among the present invention, just are used as the rose water of eye drop.And Oleum Rosae Rugosae does not find can be used as the purposes of eye drop at present as yet.
The present invention solves the technical scheme that its technical problem takes:
A kind of rose water eye drop, it contains rose water as effective ingredient.
Described rose water is to make with Flos Rosae Rugosae and water distillation, the weight ratio of Flos Rosae Rugosae and water is 1: 1～10, distillation speed per hour is that distillate accounts for 2～20% of Total Water, distillation time is 30 minutes to 10 hours, stop distillation, after distillate leaves standstill 1 hour, the water in the distillate is taken out, this water is rose water.
As the eye drop composition beyond the rose water, eye drop in the past is the same, can be according to different purposes, suitably, can also suitably add effective ingredients such as vitamins, antibacterial, anti-inflammatory agent, anti-allergic agent, hydryllin and vasoconstrictor with various isotonic agents, buffer agent, PH regulator, antiseptic and surfactant etc.Pure water can add in right amount, also can replace pure water with rose water.
The usage of eye drop: this eye drop is splashed in the conjunctival sac of suffering from eye, close order for a moment after dripping.Consumption: every day 3-5 time, each 1-2 drips.Recommend the course of treatment: trachoma, conjunctivitis 7 days, keratitis 10-14 days.Or follow the doctor's advice.
The eye drop of gained of the present invention all has very high effective percentage and cure rate to trachoma, conjunctivitis and keratitis sicca.Respectively 100 cases of this three classes disease are used, it the results are shown in following table 1.
The effect of table 1 eye drop of the present invention
For trachoma, the patient can be conscious eye itch, burn feeling, sx such as shed tears, it is effective to can be considered this eye drop; And above symptom is eliminated or basic the elimination, is considered as curing.For keratitis sicca, patient's burn feeling alleviates, eye secretions begins to reduce, and it is effective to can be considered this eye drop; And following symptom is eliminated or basic the elimination, is considered as curing: eyes are dry and astringent, burn feeling, secretions increase, photophobia and absent lacrimation, and tear does not increase yet during the emotion irriate.For epidemic conjunctivitis (being commonly called as " pink eye disease "), patient's eye redness, congested symptom begin to disappear, and secretions begins to reduce, and it is effective to can be considered this eye drop; And above symptom is eliminated or basic the elimination, is considered as curing.
Eye drop in the past, being used for eye health protection (for example: eliminate fatigue that excess eye-using causes etc.) often has following untoward reaction: have behind the eye drip local excitation sense and (or) the conjunctival sac secretions increase.And the eye drop of gained of the present invention is applied to 150 people, then only finds the such untoward reaction of an example.
The invention has the advantages that: be the eye drop of primary raw material preparation by this rose water, can alleviate symptoms such as eyes discomfort such as eyestrain, dry and astringent and pruritus effectively, the infection of corneal, conjunctiva allergy or inflammation, cornea and conjunctiva is all effective in cure, and zest is very little, have efficient, low toxicity, characteristics that adverse reaction rate is low, have a extensive future.
The specific embodiment
Embodiment 1: extract rose water with fresh rose flower
With fresh rose flower 100 grams, add 400 gram water, put into distillating still and feed water vapour, carry out steam distillation, and steam is cooled off, distillation speed is 10%, distillation was carried out 2 hours 30 minutes, when distillate reaches 100 grams, stopped still-process.Distillate was left standstill 1 hour, the water in the distillate is taken out, this water is exactly the rose water of indication of the present invention.
Embodiment 2: extract rose water with the Flos Rosae Rugosae dry flower
With Flos Rosae Rugosae dry flower 100 grams, add 500 gram water, put into distillating still and feed water vapour, carry out steam distillation, and steam is cooled off, distillation speed is 20%, distillation was carried out 5 hours, when distillate reaches 500 grams, stopped still-process.Distillate was left standstill 1 hour, the water in the distillate is taken out, this water is exactly the rose water of indication of the present invention.
Embodiment 3: extract rose water with fresh rose flower
With fresh rose flower 100 grams, add 400 gram water, put into distillating still, the direct heating distillating still carries out water distillation, and steam is cooled off, and distillation speed is 5%, and distillation was carried out 30 minutes, when distillate reaches 10 grams, stopped still-process.Distillate was left standstill 1 hour, the water in the distillate is taken out, this water is exactly the rose water of indication of the present invention.
Embodiment 4: extract rose water with the Flos Rosae Rugosae dry flower
With Flos Rosae Rugosae dry flower 100 grams, add 500 gram water, put into distillating still, the direct heating distillating still carries out water distillation, and steam is cooled off, and distillation speed is 2%, and distillation was carried out 10 hours, when distillate reaches 100 grams, stopped still-process.Distillate was left standstill 1 hour, the water in the distillate is taken out, this water is exactly the rose water of indication of the present invention.
Embodiment 5: eye drop prepares embodiment
The raw material of preparation eye drop such as following:
Chlorphenamine 0.03g
Glycyrrhizic acid dipotassium 0.25g
Sodium chloride 0.5g
L-glutamic acid is received 0.2g
Benzalkonium chloride 0.005g
Methaform 0.2g
Menthol 0.01g
Sodium hydroxide is an amount of
Rose water is an amount of
In turn chlorphenamine, glycyrrhizic acid dipotassium, sodium chloride, the L-glutamic acid of above-mentioned weight are received, benzalkonium chloride, methaform be dissolved in about 70ml rose water, disperse and add in the above-mentioned solution with menthol, adjust pH value to 5.5 with sodium hydroxide, it is 100ml to full dose that the adding rose water makes it.After the sterilization, fill it in the container (being commonly called as " polyester bottles ") of poly terephthalic acid second hexichol alcohol ester of 15ml.
More than rose water eye drop provided by the present invention is described in detail, used specific case herein principle of the present invention and embodiment are set forth, the explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof; Simultaneously, for one of ordinary skill in the art, according to thought of the present invention, the part that all can change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.
Claims (2)
1. one kind is the purposes of eye drop in preparation treatment trachoma, conjunctivitis and keratitis sicca medicine of primary raw material with the rose water, described rose water is to make with Flos Rosae Rugosae and water distillation, the weight ratio of Flos Rosae Rugosae and water is 1: 1～10, distillation speed per hour is that distillate accounts for 2～20% of Total Water, distillation time is 30 minutes to 10 hours, stops distillation, after distillate leaves standstill 1 hour, water in the distillate is taken out, and this water is rose water.
2. purposes according to claim 1 is characterized in that, the composition of described eye drop is:
Chlorphenamine 0.03g
Glycyrrhizic acid dipotassium 0.25g
Sodium chloride 0.5g
L-sodium glutamate 0.2g
Benzalkonium chloride 0.005g
Methaform 0.2g
Menthol 0.01g
It is 5.5 that sodium hydroxide makes the pH value of eye drop
It is 100ml that rose water makes the volume of eye drop;
Chlorphenamine, glycyrrhizic acid dipotassium, sodium chloride, L-sodium glutamate, benzalkonium chloride, methaform with above-mentioned weight is dissolved in the 70ml rose water in turn, disperse and add in the above-mentioned solution with menthol, adjust pH value to 5.5 with sodium hydroxide, it is that 100ml promptly obtains described eye drop to full dose that the adding rose water makes it.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610150185XA CN1943650B (en) | 2006-10-30 | 2006-10-30 | Rose liquid eye drops |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610150185XA CN1943650B (en) | 2006-10-30 | 2006-10-30 | Rose liquid eye drops |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1943650A CN1943650A (en) | 2007-04-11 |
| CN1943650B true CN1943650B (en) | 2011-04-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200610150185XA Expired - Fee Related CN1943650B (en) | 2006-10-30 | 2006-10-30 | Rose liquid eye drops |
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| Country | Link |
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| CN (1) | CN1943650B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327197B (en) * | 2010-07-12 | 2013-03-27 | 山东省科学院生物研究所 | Natural pale-yellow green rose water and preparation method |
| CN102940700A (en) * | 2012-12-08 | 2013-02-27 | 昆明戈尔登纯净水有限公司 | Method for preparing rose extracting solution, rose water taking rose extracting solution as active ingredient, and preparation method of rose water |
| CN105726698B (en) * | 2016-03-25 | 2020-02-28 | 甘肃东方天润玫瑰科技发展有限公司 | Rose composition and eye mask for relieving visual fatigue and preparation method thereof |
| CN105726697B (en) * | 2016-03-25 | 2020-02-28 | 甘肃东方天润玫瑰科技发展有限公司 | Anti-asthenopia rose composition, eye drop and preparation method of eye drop |
| FR3088196B1 (en) * | 2018-11-08 | 2022-03-25 | Abdeslem Alain Kitkit | DEVICE FOR IMPROVING SIGHT CONSISTS OF A SOLUTION IN A BOTTLE WITH A TREATMENT AND WASH |
| CN110420260A (en) * | 2019-09-19 | 2019-11-08 | 东莞市卫花生物科技有限公司 | A kind of antibacterial eye refreshing drop moistening asthenopia desalination eye circumference microgroove of releiving |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1280836A (en) * | 2000-07-13 | 2001-01-24 | 贵阳高新顺业生物科技有限公司 | Buccal rose lozenge and its preparing process |
| CN1410111A (en) * | 2002-10-31 | 2003-04-16 | 南开大学 | Rose extract and its application |
| CN1412287A (en) * | 2001-10-16 | 2003-04-23 | 舟山明日纳米材料有限公司 | Essence, its preparation and application |
| CN1431286A (en) * | 2002-01-10 | 2003-07-23 | 田永元 | Natural rose perfume and its production method |
| CN1537928A (en) * | 2003-10-22 | 2004-10-20 | 徐州市小康食品有限公司 | Method of extracting rose juice and rose oil from fresh rose flower |
| CN1849111A (en) * | 2003-09-10 | 2006-10-18 | 千寿制药株式会社 | Ophthalmic composition for contact lens |
-
2006
- 2006-10-30 CN CN200610150185XA patent/CN1943650B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1280836A (en) * | 2000-07-13 | 2001-01-24 | 贵阳高新顺业生物科技有限公司 | Buccal rose lozenge and its preparing process |
| CN1412287A (en) * | 2001-10-16 | 2003-04-23 | 舟山明日纳米材料有限公司 | Essence, its preparation and application |
| CN1431286A (en) * | 2002-01-10 | 2003-07-23 | 田永元 | Natural rose perfume and its production method |
| CN1410111A (en) * | 2002-10-31 | 2003-04-16 | 南开大学 | Rose extract and its application |
| CN1849111A (en) * | 2003-09-10 | 2006-10-18 | 千寿制药株式会社 | Ophthalmic composition for contact lens |
| CN1537928A (en) * | 2003-10-22 | 2004-10-20 | 徐州市小康食品有限公司 | Method of extracting rose juice and rose oil from fresh rose flower |
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| Publication number | Publication date |
|---|---|
| CN1943650A (en) | 2007-04-11 |
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