CN1850126A - Propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule and preparing process therefor - Google Patents

Propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule and preparing process therefor Download PDF

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CN1850126A
CN1850126A CNA2006100097464A CN200610009746A CN1850126A CN 1850126 A CN1850126 A CN 1850126A CN A2006100097464 A CNA2006100097464 A CN A2006100097464A CN 200610009746 A CN200610009746 A CN 200610009746A CN 1850126 A CN1850126 A CN 1850126A
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polysaccharide
propolis
auricularia
ethanol
powder
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CN100488381C (en
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陈福存
王振清
王德生
郭书刚
张军
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Abstract

The present invention relates to a propolis genoderma spore powder Jew's ear polysaccharide composite soft capsule and its preparation process. Its main composition includes the following components: Jew's ear extract polysaccharide powder, propolis, ganoderma and pine seed oil which is used as main components, and vitamin E as auxiliary component.

Description

Propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule and preparation technology thereof
Affiliated field: the present invention relates to a kind of clever soft capsule and preparation technology thereof.
Background technology: present nutraceutical is more, the overall absorption weak effect, and edible not only inconvenience but also influence absorption, and existing processing technique is coarse, can not effectively discharge the ability of the complementation of multiple nutrients material, enriched nutritive effect.
Summary of the invention: the purpose of this invention is to provide a kind of absorption that helps the person, have the propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule and the preparation technology thereof of health care and better nutritive validity.The objective of the invention is to be achieved through the following technical solutions a kind of clever soft capsule and preparation technology thereof, the compound clever soft capsule of Auricularia propolis, its constituent is calculated as with 0.5 gram/grain:
Auricularia polycose powder 100----150 milligram
Propolis 100----150 milligram
Ganoderma spore powder 50----100 milligram
Vitamin E 1----10 milligram
YANSONGZI oil 100----250 milligram
Preparation technology of the present invention is: the Auricularia that (1) will clean after drying advances mechanical activation comminution, granularity is controlled at about 20 orders, promptly earlier 20 purpose Auricularia raw materials are put into container, the ethanol 90----95 degree V/V that adds 5 times of raw materials, stir, capping was soaked 1 hour, with the ethanol recover ethanol was reclaimed then; (2) the Auricularia powder after will handling is put into basin, carries out enzymolysis processing, adds the water of 40 times of raw material weights earlier, adjusts pH value scope 4.5----5.0, heat to 50----55 degree centigrade, add pectase 1%, proteinase-10 .8%, start agitator and be mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (3) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.5----3.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (4) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, and (5) concentrate: use vacuum concentration pot, above-mentioned filtrate is concentrated, contain polysaccharide about 2.0 in the liquid after concentrated; (6) alcohol precipitation: with the metering of polysaccharide concentrated solution, add the 95%V/V ethanol of 2 times of volumes of concentrated solution, in precipitate with ethanol under 4----10 degree centigrade the temperature about 10 hours; (7) filter: the solution behind the precipitate with ethanol is carried out isolated by filtration, obtain polysaccharide precipitation, liquid reclaims by ethanol, and deposit mixes and carries out drying, promptly obtains polysaccharide; (8) drying: the polysaccharide precipitation material is carried out vacuum drying, and temperature is controlled at about 60 degree, prevents the polysaccharide degeneration; (9) pulverize: the polysaccharide dry matter is put into high speed disintegrator pulverize, reach the 120----200 order and be advisable, package spare; (10) mixing of powder: Auricularia polysaccharide powder, chitin, zinc gluconate are established material by formula proportion mix, require to stir, be through sterilization treatment; (11) mixing of oil preparation: YANSONGZI oil, vitamin E are mixed; (12) slurrying is handled: powder intermixture and oil preparation intermixture are mixed, handle through the mechanical agitation making beating, handle through colloidal grinding, obtain the oil preparation mixed serum, be incubated under 50 degrees centigrade of situations, prepare next procedure and make flexible glue; (13) glue: have blender and heating, cooling, insulation, system vacuum function in the glue jar, after the tank body sterilization, put into the steaming slide earlier and be heated to 80 degrees centigrade, add gelatin again, solid-to-liquid ratio is 1: 2, add an amount of glycerol again and stir, evacuation 4 hours is cooled to 50 degrees centigrade, be incubated 2 hours, be put in the jar that links to each other with pellet processing machine, follow procedure starts pellet processing machine, makes soft capsule.
Formula combination of the present invention is novel unique, and the scientific basis original creation effectively improves the effect of functional component to health.The innovation of formula combination: mainly be from Auricularia, to extract Auricularia polycose with scientific method, be equipped with the exclusive YANSONGZI oil in Daxing'an Mountainrange, propolis, Ganoderma spore powder, vitamin E again, improved the invigoration effect of product efficacy composition, improved the absorption rate of human body to efficiency factor, improved health-care effect greatly, so this formula combination is an initiative in the health food, newly show the domestic beyond example of this combination formula through looking into.Extracting method adopts physical pulverization, and the ethanol extraction new technology is decomposed in the plurality of enzymes combination.The physical pulverization granularity is generally about 120 orders, in order to reduce granularity, and make polysaccharide yield higher, adopt multi-enzyme method technology, main with pectase, protease, Ye Huamei etc., make grain refine, the crushed after being dried degree reaches 200 orders, to raw material yield 9.6-10.4%, adopt multiple powder to mix with oil preparation, homogenizing is handled and is made soft capsule, and this technology is the innovation that single oil preparation is made soft capsule, has the value of originality and extensive use.Make the product efficacy enhancing with five kinds of combination of active principles, strengthen absorbing of the person, strengthen health food, health care and nutrition balance, this technology is the compatibility innovation.The combination material is Auricularia polycose, propolis, Ganoderma spore powder, YANSONGZI oil, vitamin E.Do not appear in the newspapers at home through looking into newly, fill the domestic gaps real the genus.
The specific embodiment: the present invention is a kind of soft capsule and preparation technology thereof, propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule, and its constituent is calculated as with 0.5 gram/grain:
Auricularia polycose powder 100----150 milligram
Propolis 100----150 milligram
Ganoderma spore powder 50----100 milligram
Vitamin E 1----10 milligram
YANSONGZI oil 100----250 milligram
Concrete constituent in the present embodiment is every 0.5 gram: Auricularia polycose powder 0.1, propolis 0.1g Ganoderma spore powder 0.05g, vitamin E 0.001g, YANSONGZI oil 0.25g.
Preparation technology of the present invention is: the Auricularia that (1) will clean after drying advances mechanical activation comminution, granularity is controlled at about 20 orders, promptly earlier 20 purpose Auricularia raw materials are put into container, the ethanol 90----95 degree V/V that adds 5 times of raw materials, stir, capping was soaked 1 hour, with the ethanol recover ethanol was reclaimed then; (2) the Auricularia powder after will handling is put into basin, carries out enzymolysis processing, adds the water of 40 times of raw material weights earlier, adjusts pH value scope 4.5----5.0, heat to 50----55 degree centigrade, add pectase 1%, proteinase-10 .8%, start agitator and be mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (3) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.5----3.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (4) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, and (5) concentrate: use vacuum concentration pot, above-mentioned filtrate is concentrated, contain polysaccharide about 2.0 in the liquid after concentrated; (6) alcohol precipitation: with the metering of polysaccharide concentrated solution, add the 95%V/V ethanol of 2 times of volumes of concentrated solution, in precipitate with ethanol under 4----10 degree centigrade the temperature about 10 hours; (7) filter: the solution behind the precipitate with ethanol is carried out isolated by filtration, obtain polysaccharide precipitation, liquid reclaims by ethanol, and deposit mixes and carries out drying, promptly obtains polysaccharide; (8) drying: the polysaccharide precipitation material is carried out vacuum drying, and temperature is controlled at about 60 degree, prevents the polysaccharide degeneration; (9) pulverize: the polysaccharide dry matter is put into high speed disintegrator pulverize, reach the 120----200 order and be advisable, package spare; (10) mixing of powder: Auricularia polysaccharide powder, chitin, zinc gluconate are established material by formula proportion mix, require to stir, be through sterilization treatment; (11) mixing of oil preparation: with Radix Oenotherae erythrosepalae oil, vitamin E, V ASalad oil; (12) slurrying is handled: powder intermixture and oil preparation intermixture are mixed, handle through the mechanical agitation making beating, handle through colloidal grinding, obtain the oil preparation mixed serum, be incubated under 50 degrees centigrade of situations, prepare next procedure and make flexible glue; (13) glue: have blender and heating, cooling, insulation, system vacuum function in the glue jar, after the tank body sterilization, put into the steaming slide earlier and be heated to 80 degrees centigrade, add gelatin again, solid-to-liquid ratio is 1: 2, add an amount of glycerol again and stir, evacuation 4 hours is cooled to 50 degrees centigrade, be incubated 2 hours, be put in the jar that links to each other with pellet processing machine, follow procedure starts pellet processing machine, makes soft capsule.
The processing technique of propolis of the present invention is: (1) cleans propolis, and earlier with propolis roguing dewax, (2) are cut into small pieces then.(3) dipping: ethanol and propolis are poured in the impregnating autoclave, stirred, make ethanol submergence propolis, stir later every day 1~2 time, mixture was placed for 2 weeks in warm place lucifuge.(4) filter: after flooding for two weeks, liquid is filtered 2 times with 100 order filter clothes.(5) drying: adopt spray drying process to carry out drying.(6) check: through the product warehousing that is up to the standards.
The processing technique of Ganoderma spore powder of the present invention is: (1) cleans: remove non-Ganoderma impurity.(2) cutting: will clean qualified Ganoderma and be cut into small pieces.(3) drying: Ganoderma gone in the hot air circulation drying oven carry out drying with 60 ℃~65 ℃, moisture is being qualified below 6%.(4) pulverize: adopt a times power pulverizer to pulverize.(5) check: microscopic examination, grinding particle size: medium particle diameter is qualified below 5~10 μ m.(6) warehouse-in: product warehousing is up to the standards.
Prescription of the present invention is main according to being " centre halfback No. 2002.51 " file of issuing of the Pharmacopoeia of the People's Republic of China, health ministry in the pertinent regulations, " Chinese health food progress " etc. that are the nutraceutical of polyphagia with emaciation medicine and health food, ad hoc meter formula for a product.
One, Auricularia polycose
Auricularia polycose is to be raw material with the Auricularia that northeast abounds with, the Auricularia polycose material that extracts by scientific method.
The biological character of black ear: Auricularia, be called for short Auricularia, Basidiomycetes, Auriculariaceae, the sporophore of Auricularia has another name called black dish, Mulberry, and another names such as timber fungus, tree chicken, wooden moth, wooden young pilose antler are arranged again, belongs to wild edible fungus.Be born on the rotten wood such as fried, Mulberry, ashamed, willow, elm, ancient times is called five Auricularias.Auricularia is a kind of saprophytic fungus of warm nature, relies on the dried growth and breeding of straw of broad leaf tree.Heilungkiang is the township that abounds with natural Auricularia, the mountain area around the Daxing'an Mountainrange, the Xiaoxinanlin Mountains particularly, abound with the natural and pollution-free green Auricularia, big nutritious, the delicious flavour of thick of fine quality, ear, contain protein, Auricularia polysaccharide, multivitamin and trace element, be subjected to the welcome and the favor in broad masses and restaurant especially deeply.
The active ingredient of Auricularia: Auricularia meat exquisiteness, tender deliciousness, main is that Auricularia contains rich in protein, protein content 10.6g/100g in dry product, carbohydrate 65g/100g, wherein more than the Auricularia polysaccharide 2000mg/100g, fatty 0.2g/100g, calcium 357mg/100g, phosphorus 201mg/100g, ferrum 185mg/100g (higher 13 times than egg) also have quite high Hu square-bottomed bamboo basket Bu Su, thiamine, riboflavin, nicotinic acid, phospholipid, sterol, VB 1, VB 2, PP etc., and contain more colloid, the effect of extraordinary vigorate qi and replenish the blood, lung moistening calmness, bowel relieving are arranged, washing intestinal.
The health care of Auricularia: modern scientific research shows that Auricularia has the effect of antiplatelet aggregation, and can reduce the cholesterol level in the blood.Auricularia can be improved the phagocytic index and the percentage rate of mouse macrophage, to the animal of 60 ℃ of irradiations, can improve its survival rate, prove radiation resistance, can resist the caused leukopenia of chemicals because of the treatment tumor, Auricularia can also promote proteic biosynthesis in the mice serum.Owing to contain more Auricularia polysaccharide and materials such as colloid, vitamin in the Auricularia, the mankind there are blood sugar lowering, blood fat, the effect of fat-reducing is arranged.
Two, propolis: propolis is universally acknowledged nutrient and healthcare products.Propolis is later owing to what it is found that, and development and use are especially because of biological purification technique of modern times just is achieved, so a lot of people may be also stranger to propolis.The Chinese and foreign department scholar saying through the back praise of concentrating on studies, and propolis is perfect natural broad-spectrum antibiotics; It is natural immunity reinforcing agent; Be the street cleaner of blood vessel; Be healthy patron saint; It is natural antioxidant ...Become magical propolis through the modern science and technology analysis, the elite of propolis collection animals and plants, composition is very complicated, multiple very strong biological active substances is wherein arranged, as flavonoid, phenols, terpenes, organic acid and several amino acids, enzyme, vitamin, mineral etc.Oxonian research worker finds, in contained more than the 200 kind of composition of propolis, have 100 surplus the natural crude drug composition of kind, so there is the people to say, propolis similarly is one " a little Drug Storage ".As aspect antibiotic, the antioxidation, propolis is used for the storing and fresh-keeping of muscle, liver, kidney and other tissue, no abnormal variation in six months.The aqueous solution that propolis is mixed with concentration lower (0.03%) is used for fruit freshness preserving, and percentage of water loss, decayed fruit rate all reduce greatly after 147 days.Propolis has very strong antibacterial, sterilizing ability, but it and synthetics have the difference of essence, and its Nantural non-toxic is not only effectively gentle, and has no side effect, and is described as the most perfect antibiotics by scientist.Flavone compound in the propolis and various active composition can make ATP increase, and discharge the energy that the more mankind depend on for existence.Enough ATP are arranged in the cell, just tired material such as lactic acid and other toxic metabolites can be excreted smoothly, make people's relaxation and happiness, be difficult for old and feeble and sick.These material compositions also can effectively reduce capillary permeability, prevent sclerosis of blood vessels, microcirculation improvement, but and blood fat reducing, blood sugar lowering, blood pressure lowering, the prevention various diseases.Evidence, propolis can strengthen body immunity effectively, promotes cytophagous effect, stimulates health to produce antibody, is a kind of natural immunity reinforcing agent of preciousness.Nowadays, propolis has been widely used in many fields such as medicine, health care, cosmetics.
Three, seed of Dwarf Siberian Pine oil: seed of Dwarf Siberian Pine is the peculiar resource of Daxinganling District, is grown in 800 meters mountain tops of height above sea level.Therefore the siberian dwarf pine fruit claims fruit on the thousand again because of 1,000 genius results.Seed of Dwarf Siberian Pine oil contains more than the 100 kind of composition to the human body beneficial, is rich in multiple unsaturated fatty acids such as phospholipid, vitamin E, vegetable protein, linoleic acid, linolenic acid and arachidonic acid, easily is the absorption of human body utilization.Have cholesterol level in the U.S. face of nourishing the brain and improving intelligence, anti-ageing life-prolonging, skin moistening, loosening bowel to relieve constipation, the reduction blood, prevent the effect of arteriosclerosis, blood fat reducing, blood pressure lowering.Abundant linoleic acid, linolenic acid, acid and gamma-linolenic have the effect of extraordinary cholesterol reducing and triglyceride.Aspect the inhibition vasoconstriction, Oleum pini koraiensis is premier in addition.In a single day blood vessel shrinks, and blood vessel will narrow down, and blood pressure will raise.Hypertension can cause various dysfunctions, and this point is well-known.Because contain a large amount of Pinolenic acids in the seed of Dwarf Siberian Pine oil, it can reduce the concentration of blood cholesterol and triglyceride, and can suppress the harmful effect of diabetes to human body; Regulate water-electrolyte metabolism and bring high blood pressure down; Suppress the damage of radical pair human body, it can also promote the release of interferon and lymphocyte factor in addition, and activation NK cell kills, anticancer, so it also has anticancer effect, can prevent chromosomal damage; Defying age reduces the accumulation at liver of the fat that caused by ethanol.Moreover, the unique advantage of its maximum also is its unsaturated fatty acid position difference, can not become other harmful substances in human body, because it has overcome the secondary face sound of other unsaturated fatty acid to human body, therefore, can eliminate the adverse effect of linoleic acid plus linolenic acid to human body.If we eat a certain amount of pine nut or Oleum pini koraiensis every days, your body constitution can be improved at all so, and healthy meeting accompanies you lifelong.
Four, Ganoderma: Ganoderma ancient books record Ganoderma " food of a specified duration is made light of one's life by commiting suicide not old, prolongs life ".Ganoderma is the diastole coronary artery effectively, coronary blood flow increasing, improve myocardium microcirculation, increase myocardial oxygen delivery, can be used for coronary heart disease, anginal treatment and prevention, Ganoderma can be regulated nervus centralis, improve end arteriosclerosis, the reinforcement cardiac function of blood vessel slightly, vessel softening has two-way Accommodation to blood pressure: reduce hypertension, the rising hypotension.To hyperlipemia, can prevention of arterial atherosclerotic plaque form, and can purify the blood, prevent and dissolve thrombosis.These functions have good preventive and therapeutic effect for polytype apoplexy.Ganoderma has the characteristics of " dietotherapeutic " from ancient times, and the attribute of its " strengthening the body resistance " has determined it can help the human righteousness, and Ganoderma is improved the immunocompetence of human body from cellular immunization and humoral immunization two aspects, strengthened the resistivity to disease.Moisture of skin can be regulated and keep to Ganoderma, recovers melanic telogenesis and precipitation in the skin.Ganoderma also can make complexion fine and glossy glossy, i.e. ancient book contained " good color ".
Five, vitamin E: the active form of vitamin E tool has 8 kinds, and promptly residual acid is in enol, but to remain alcohol, it represents vitamin E.Vitamin E is a kind of Polyphenols, and very strong antioxidation is arranged, and resists body peroxidating product free radical damage, becomes topmost active substance in the gerocomia food.
Can stop fat oxidation in food and the digestive tract as antioxidant, the protection human body cell is avoided the toxicant injury that the unsaturated fatty acids acid oxidase produces.Vitamin E self is prior to other material generation oxidations in vivo, thereby makes unsaturated fatty acid and vitamin A oxidation Decomposition in intestinal and tissue reduce to minimum degree.The biological action of vitamin E is to suppress polyunsaturated fatty acid oxidation in the tissue film, the lipid part of stabilized cell, and the protection cell is not subjected to poisonous free radical injury, prevents to wear out, and prevents organic trace to move back the aspect and works.Vitamin E can be treated hemolytic anemia as the necessary factor of protection erythrocyte integrity in addition; As the necessary factor of Cellular respiration, be that cardiac muscle and skeletal muscle tissue are breathed desired material, as the synthetic regulator of chemical compound in the body, participate in the synthetic of DNA, also may be the synthetic cofactor of vitamin C and coenzyme; Exempt from air-polluting and ruin agent as the protection lung tissue, vitamin E can also with the iodine synergism, vitamin E and iodine all are antioxidants, but both action pathway differences.
Vitamin E has protective effect on cancer risk, can prevent that chromosome from very becoming, and strengthens the activity of micropartical mixed-function oxidase, influences the carcinogen metabolism, and blocking nitrosamine formation is synthetic etc., thereby can give protection against cancer.Can strengthen the effect of DHA and EPA.Behind the scientific combination prescription, has excellent cleaning blood vessel, the effect of blood lipid regulation.

Claims (2)

1, a kind of propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule is characterized in that: its constituent is calculated as with 0.5 gram/grain:
Auricularia polycose powder 100----150 milligram
Propolis 100----150 milligram
Ganoderma spore powder 50----100 milligram
Seed of Dwarf Siberian Pine oil 100----250 milligram
Vitamin E 1----10 milligram
2, a kind of preparation technology of propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule, it is characterized in that: the Auricularia that (1) will clean after drying advances mechanical activation comminution, granularity is controlled at about 20 orders, promptly earlier 20 purpose Auricularia raw materials are put into container, the ethanol 90----95 degree V/V that adds 5 times of raw materials, stir, capping was soaked 1 hour, with the ethanol recover ethanol was reclaimed then; (2) the Auricularia powder after will handling is put into basin, carries out enzymolysis processing, adds the water of 40 times of raw material weights earlier, adjusts pH value scope 4.5----5.0, heat to 50----55 degree centigrade, add pectase 1%, proteinase-10 .8%, start agitator and be mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (3) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.5----3.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (4) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, and (5) concentrate: use vacuum concentration pot, above-mentioned filtrate is concentrated, contain polysaccharide about 2.0 in the liquid after concentrated; (6) alcohol precipitation: with the metering of polysaccharide concentrated solution, add the 95%V/V ethanol of 2 times of volumes of concentrated solution, in precipitate with ethanol under 4----10 degree centigrade the temperature about 10 hours; (7) filter: the solution behind the precipitate with ethanol is carried out isolated by filtration, obtain polysaccharide precipitation, liquid reclaims by ethanol, and deposit mixes and carries out drying, promptly obtains polysaccharide; (8) drying: the polysaccharide precipitation material is carried out vacuum drying, and temperature is controlled at about 60 degree, prevents the polysaccharide degeneration; (9) pulverize: the polysaccharide dry matter is put into high speed disintegrator pulverize, reach the 120----200 order and be advisable, package spare; (10) mixing of powder: Auricularia polysaccharide powder, Ganoderma spore powder, propolis are established material by formula proportion mix, require to stir, be through sterilization treatment; (11) mixing of oil preparation: YANSONGZI oil, vitamin E are mixed; (12) slurrying is handled: powder intermixture and oil preparation intermixture are mixed, handle through the mechanical agitation making beating, handle through colloidal grinding, obtain the oil preparation mixed serum, be incubated under 50 degrees centigrade of situations, prepare next procedure and make flexible glue; (13) glue: have blender and heating, cooling, insulation, system vacuum function in the glue jar, after the tank body sterilization, put into the steaming slide earlier and be heated to 80 degrees centigrade, add gelatin again, solid-to-liquid ratio is 1: 2, add an amount of glycerol again and stir, evacuation 4 hours is cooled to 50 degrees centigrade, be incubated 2 hours, be put in the jar that links to each other with pellet processing machine, follow procedure starts pellet processing machine, makes soft capsule.
CNB2006100097464A 2006-02-27 2006-02-27 Propolis ganoderma lucidum spore, dried black fungus polysaccharide compounded soft capsule and preparing process therefor Expired - Fee Related CN100488381C (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103262973A (en) * 2013-04-24 2013-08-28 张�荣 Auricularia auricula polysaccharide-pine nut oil composite soft-capsule
CN105919073A (en) * 2016-04-25 2016-09-07 孙继勇 Vacant plant capsules made from wall-breaking glossy ganoderma spore powder and making method of vacant plant capsules
CN106616185A (en) * 2017-01-04 2017-05-10 云南农业大学 Processing process of health type coix seed solid beverage
CN113115948A (en) * 2019-12-30 2021-07-16 黑龙江北货郎森林食品有限公司 A health food containing Auricularia auricula polysaccharide and its preparation method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103262973A (en) * 2013-04-24 2013-08-28 张�荣 Auricularia auricula polysaccharide-pine nut oil composite soft-capsule
CN105919073A (en) * 2016-04-25 2016-09-07 孙继勇 Vacant plant capsules made from wall-breaking glossy ganoderma spore powder and making method of vacant plant capsules
CN106616185A (en) * 2017-01-04 2017-05-10 云南农业大学 Processing process of health type coix seed solid beverage
CN113115948A (en) * 2019-12-30 2021-07-16 黑龙江北货郎森林食品有限公司 A health food containing Auricularia auricula polysaccharide and its preparation method

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