CN1486710A

CN1486710A - Chinese medicine for health care and treating fatty liver

Info

Publication number: CN1486710A
Application number: CNA021594481A
Authority: CN
Inventors: 张立中
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-12-31
Filing date: 2002-12-31
Publication date: 2004-04-07
Anticipated expiration: 2022-12-31
Also published as: CN1241624C

Abstract

The Chinese medicine for health care and treating fatty liver consists of assam tea leaf, licorice, wolfberry fruit, cassia seed, prslane, haw and other eight kinds of Chinese medicinal materials. It may be prepared into tea preparation, granule, oral liquid or other forms. It has functions of obviously lowering fat in liver and is ideal preparation for liver health care and treating fatty liver.

Description

The Chinese medicine preparation of a kind of health care, treatment fatty liver

The present invention is a kind of preparation that the Patients with Fatty Liver health care combines with treatment of specializing in.It is a raw material with Chinese medicine, can be made into medicinal tea, oral liquid, electuary etc.

China has 1,500 ten thousand chronic hepatitis patients approximately, and the ratio that its chronic hepatitis merges fatty liver is 86.2％。And the obese fatty liver number of the infected is more, and 50% obesity merging fatty liver is arranged approximately.Fatty liver is the key factor that causes liver cirrhosis.It is significant to the prevention liver cirrhosis to eliminate fatty liver.But still lack at fatty liver health care and the significant Chinese medicine preparation of therapeutic effect at present.

The present invention is on clinical practice basis for many years, constantly sums up to improve and improves the desirable preparation that is developed into.Through clinical observation, in conjunction with patient's actual needs, for executing the means of controlling, effective percentage reaches 100% with the tea medicine.

Medicine of the present invention is made up of Folium camelliae assamicae, Radix Glycyrrhizae, Fructus Lycii, Semen Cassiae, Herba Portulacae, Fructus Crataegi, Fructus Citri Sarcodactylis, Folium Perillae, Folium Nelumbinis, Rhizoma Polygoni Cuspidati, Ganoderma, Rhizoma Polygonati, Radix Polygoni Multiflori, Herba Taraxaci.

Medicine compositing range of the present invention is: Folium camelliae assamicae 5-10 gram Radix Glycyrrhizae 5-10 gram Fructus Lycii 5-10 gram Semen Cassiae 5-10 KEMA bitterroot 5-10 gram Fructus Crataegi 5-10 gram Fructus Citri Sarcodactylis 5-10 gram Folium Perillae 10-12 Rhizoma Polygoni Cuspidati 5-10 gram Folium Nelumbinis 5-12 kairine sesame 5-10 gram Rhizoma Polygonati 5-10 gram Radix Polygoni Multiflori 5-10 gram Herba Taraxaci 10-15 gram.

The present invention's each component weight proportion of filling a prescription is: Folium camelliae assamicae 10% Radix Glycyrrhizae 5% Fructus Lycii 10% Semen Cassiae 5% Herba Portulacae 5% Ganoderma 5% Fructus Crataegi 8% Fructus Citri Sarcodactylis 5% Folium Perillae 10% Folium Nelumbinis 12% Rhizoma Polygoni Cuspidati 5% Rhizoma Polygonati 5% Radix Polygoni Multiflori 5% Herba Taraxaci 10%

The processing technique of medicine medicinal tea of the present invention is:

The medicine of formula ratio is chosen decontamination, oven dry, pulverizing, mixing sieve, pack in the sterilising filtration tea bag, seal promptly.Have on the tea bag to lead and carry short-term.

Medicine of the present invention can also be made conventional pharmaceutical dosage form except can making above-mentioned medicinal tea, as electuary, and oral liquid, tablet, capsule etc.

The preparation technology of electuary of the present invention is:

By above-mentioned formula ratio, the herbal raw material medicine is chosen decontamination, mixed powder is broken into coarse powder (5-10 order), put into extraction pot, the water that adds 3 times of amounts of crude drug weight boils back slow fire and boiled one hour again, leaches medicinal liquid, and then the water of adding Chinese herbal medicine weight qdx, boil back slow fire and boil half an hour again, leach medicinal liquid, front and back secondary medicinal liquid is merged, the cooling back adds 1-2 and doubly measures fully mixing placement of ethanol (concentration 90%), precipitation.Get its supernatant after 20 hours, precipitate is cleaned with a small amount of 50-60% ethanol, washing liquid and filtrate merge, decompression recycling ethanol, wait be concentrated to finite concentration after, again the cooling left standstill 12 hours, make thorough precipitation, filter, the filtrate low-temperature evaporation is standby to the thick paste shape, and the ratio of the thick paste side (80-90 ℃) of reheating is 1.30-1.35.Wear into fine powder with crystallization of sucrose, it is standby to cross the 80-100 mesh sieve, and it is standby to get commercially available dextrin, and Chinese herb medicine thick paste, Icing Sugar, dextrin are got finished product by 1: 3: 1 weight ratio stirring and evenly mixing.

The preparation technology of oral liquid of the present invention is:

According to preparation identical prepared Chinese herbal medicine thick paste during electuary, with an amount of distilled water diluting of thick paste, filter, it is 20% that diluent contains the crude drug amount, adds simple syrup, Pyrusussuriensis potassium alcoholate (content is pressed 90 years version pharmacopeia, should be up to specification) makes the oral liquid finished product.

The present invention uses the theory of the combination of Chinese and Western medicine and method to implement the name of disease of fat-free liver in the Chinese medicine.But its performance belongs to " long-pending disease " " feeling of fullness " " costalgia " disease scopes such as " accumulation of phlegm in the hypochondrium " mostly, and is relevant with stagnation of liver-QI, phlegm-damp.We are at the prescription in principle without prejudice to traditional Chinese medical science eighteen incompatible medicaments nineteen medicaments of mutual restraint, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.If with traditional Chinese medical science typing surely belong to liver-kidney yin deficiency, caused by hepatic stagnation qi stagnation is controlled object for executing.Merge fatty liver after the hepatitis in the doctor trained in Western medicine, obese fatty liver is particularly suited the medicine to the illness.Clinical showing through taking we obviously reduced cholesterol in serum and triglyceride, improves the liver fat metabolism.Pharmacological research confirms that Fructus Crataegi, Fructus Lycii, Semen Cassiae can suppress fat and deposit in hepatocyte, have obvious lipotropy.Take we and have health care, treatment fatty liver, recover liver function, eliminate abdominal distention, aid digestion, improve effects such as uncomfortable liver area.Be a course of treatment with one month generally, state of an illness weight person can obey half a year.Through clinical observation 86 routine Patients with Fatty Liver total effective rates is 100%.

Model case:

Example 1: so-and-so man of Lee suffered from chronic viral hepatitis B in 40 years old and merges fatty liver 2 years.The state of an illness is outstanding with abdominal distention repeatedly.B ultrasonic, CT all are reported as severe fatty liver.The SGPT fluctuation is about 100U.Blood fat all doubles above

(cholesterol triglyceride) is through taking this medicated tea after five months.B ultrasonic, CT check are slight fatty liver.Blood fat is normal substantially, and SGPT is near normal.Symptoms such as patient's abdominal distention are eliminated.Follow up a case by regular visits to 1 year stable disease.

Example 2: so-and-so man of grandson suffered from obese fatty liver (moderate) 3 years in 56 years old, and the not good SGPT fluctuation of multi-treatment once is 93 kilograms of all high body weight of 60U left and right sides blood fat.Through take this medicated tea half a year, body weight is reduced to 74 kilograms, blood fat and SGPT recover normal.The B ultrasonic check is followed up a case by regular visits to state of an illness no change half a year for slight fatty liver.

Example 3: military so-and-so man suffered from obese fatty liver (moderate) 3 years in 15 years old, and is not good through multi-treatment.Liver function is undesired repeatedly.Infant abdominal distention is weak, appetite not more than once the B ultrasonic CT examination be the moderate fatty liver, after took this medicated tea three months, the infant liver function is normal.The weak elimination of abdominal distention feels more preceding strong, and appetite increases, weight loss, and B ultrasonic CT check, fatty liver is cured.

Embodiment:

10 kilograms of 5 kilograms of Herba Taraxacis of 5 kilograms of Radix Polygoni Multiflori of 5 kilograms of Rhizoma Polygonatis of 5 kilograms of Ganodermas of 12 kilograms of Rhizoma Polygoni Cuspidati of 10 kilograms of Folium Nelumbinis of 5 kilograms of Folium Perillaes of 8 kilograms of Fructus Citri Sarcodactylis of 5 kilograms of Fructus Crataegi of 5 kilograms of Herba Portulacaes of 10 kilograms of Semen Cassiaes of 5 kilograms of Fructus Lycii of 10 kilograms of Radix Glycyrrhizae of Folium camelliae assamicae

The above-mentioned raw materials medicine is chosen decontamination, dry, pulverize, sieve, in the filtration pack of the sterilization of packing into.Make 100 kilograms of teabag.

Claims

The Chinese medicine preparation of 1, a kind of health care, treatment fatty liver.The content range that it is characterized in that this medicine composition is:

Folium camelliae assamicae 5-10 gram Radix Glycyrrhizae 5-10 gram Fructus Lycii 5-10 gram Semen Cassiae 5-10 gram

Herba Portulacae 5-10 gram Fructus Crataegi 5-10 gram Fructus Citri Sarcodactylis 5-10 gram Folium Perillae 10-12

Folium Nelumbinis 5-12 gram Rhizoma Polygoni Cuspidati 5-10 kairine sesame 5-10 gram Rhizoma Polygonati 5-10 gram

Radix Polygoni Multiflori 5-10 gram Herba Taraxaci 10-15 gram.
2, medicine according to claim 1 is characterized in that the each component percentage by weight is:

Folium camelliae assamicae 10% Radix Glycyrrhizae 5% Fructus Lycii 10% Semen Cassiae 5% Herba Portulacae 5%

Fructus Crataegi 8% Fructus Citri Sarcodactylis 5% Folium Perillae 10% Folium Nelumbinis 12% Rhizoma Polygoni Cuspidati 5%

Ganoderma 5% Rhizoma Polygonati 5% Radix Polygoni Multiflori 5% Herba Taraxaci 10%.
3,, it is characterized in that it is dosage forms such as medicinal tea, electuary, oral liquid according to claim 1 and 2 described medicines.
4, according to the preparation method of claim 3 medicinal tea, it is characterized in that the medicine of formula ratio is chosen decontamination, oven dry, pulverizing, mixing are sieved, and pack in the sterilising filtration tea bag, seal promptly.Have on the tea bag to lead and carry short-term.
5, according to the preparation method of the described medicament electuary of claim 3, it is characterized in that the crude drug of formula ratio is pulverized, decocts with water, the gained medicinal liquid is condensed into thick paste, add Icing Sugar (succedaneum), dextrin, mixing makes finished product.
6, according to the preparation method of the described oral liquid of claim 3, it is characterized in that the Chinese herbal medicine dry product of formula ratio is ground into coarse powder, add the water boil one hour of crude drug weight triplication, go out medicinal liquid, add qdx water boil half an hour again, go out medicinal liquid, the secondary medicinal liquid merges, and the cooling back adds 1-2 and doubly measures the ethanol mixing, places post precipitation and gets supernatant, reclaim ethanol, concentrated supernatant leaves standstill, and filters, flash to paste, add distilled water diluting, make diluent contain in the crude drug 20%, add simple syrup again, Pyrusussuriensis potassium alcoholate (or similar product), dosage by 90 years version pharmacopeia regulations, filter sterilization, encapsulation.