CN114748613A - Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule - Google Patents
Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule Download PDFInfo
- Publication number
- CN114748613A CN114748613A CN202210550220.6A CN202210550220A CN114748613A CN 114748613 A CN114748613 A CN 114748613A CN 202210550220 A CN202210550220 A CN 202210550220A CN 114748613 A CN114748613 A CN 114748613A
- Authority
- CN
- China
- Prior art keywords
- parts
- composition
- powder
- preparation
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- 238000002360 preparation method Methods 0.000 title claims abstract description 30
- 239000003053 toxin Substances 0.000 title claims abstract description 25
- 231100000765 toxin Toxicity 0.000 title claims abstract description 25
- 239000002775 capsule Substances 0.000 title claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 51
- 210000002826 placenta Anatomy 0.000 claims abstract description 41
- 241001494479 Pecora Species 0.000 claims abstract description 34
- 102000004882 Lipase Human genes 0.000 claims abstract description 29
- 108090001060 Lipase Proteins 0.000 claims abstract description 29
- 239000004367 Lipase Substances 0.000 claims abstract description 29
- 235000019421 lipase Nutrition 0.000 claims abstract description 29
- 241000234314 Zingiber Species 0.000 claims abstract description 25
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 25
- 235000008397 ginger Nutrition 0.000 claims abstract description 25
- 244000197580 Poria cocos Species 0.000 claims abstract description 21
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 11
- 239000000843 powder Substances 0.000 claims description 90
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 51
- 239000007788 liquid Substances 0.000 claims description 32
- 239000000706 filtrate Substances 0.000 claims description 27
- 238000001914 filtration Methods 0.000 claims description 25
- 238000002156 mixing Methods 0.000 claims description 25
- 238000001035 drying Methods 0.000 claims description 19
- 241000701408 Euphorbia kansui Species 0.000 claims description 14
- 238000010298 pulverizing process Methods 0.000 claims description 9
- 235000001188 Peltandra virginica Nutrition 0.000 claims description 8
- 238000004108 freeze drying Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 239000007902 hard capsule Substances 0.000 claims description 4
- 108700012359 toxins Proteins 0.000 claims 6
- 241000282461 Canis lupus Species 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 26
- 238000010792 warming Methods 0.000 abstract description 11
- 239000003814 drug Substances 0.000 abstract description 10
- 229940079593 drug Drugs 0.000 abstract description 10
- 230000008961 swelling Effects 0.000 abstract description 9
- 210000004072 lung Anatomy 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 8
- 206010011224 Cough Diseases 0.000 abstract description 7
- 206010033557 Palpitations Diseases 0.000 abstract description 6
- 206010047700 Vomiting Diseases 0.000 abstract description 6
- 208000024891 symptom Diseases 0.000 abstract description 6
- 208000011580 syndromic disease Diseases 0.000 abstract description 6
- 230000008673 vomiting Effects 0.000 abstract description 6
- 208000004880 Polyuria Diseases 0.000 abstract description 5
- 230000035619 diuresis Effects 0.000 abstract description 5
- 208000002173 dizziness Diseases 0.000 abstract description 5
- 238000010926 purge Methods 0.000 abstract description 5
- 230000001105 regulatory effect Effects 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 4
- 208000009205 Tinnitus Diseases 0.000 abstract description 4
- 208000007502 anemia Diseases 0.000 abstract description 4
- 230000002124 endocrine Effects 0.000 abstract description 4
- 230000002708 enhancing effect Effects 0.000 abstract description 4
- 230000011132 hemopoiesis Effects 0.000 abstract description 4
- 230000036039 immunity Effects 0.000 abstract description 4
- 230000001976 improved effect Effects 0.000 abstract description 4
- 208000015181 infectious disease Diseases 0.000 abstract description 4
- 230000002401 inhibitory effect Effects 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 4
- 231100000886 tinnitus Toxicity 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 206010010774 Constipation Diseases 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000010410 layer Substances 0.000 description 16
- 210000003491 skin Anatomy 0.000 description 13
- 241000283898 Ovis Species 0.000 description 8
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 210000004207 dermis Anatomy 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 230000001376 precipitating effect Effects 0.000 description 6
- 238000010992 reflux Methods 0.000 description 6
- 210000002615 epidermis Anatomy 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 235000019633 pungent taste Nutrition 0.000 description 5
- 230000000717 retained effect Effects 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- 208000002874 Acne Vulgaris Diseases 0.000 description 4
- 206010000496 acne Diseases 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 230000004089 microcirculation Effects 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 241000721047 Danaus plexippus Species 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 210000004088 microvessel Anatomy 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 230000002040 relaxant effect Effects 0.000 description 3
- 230000037380 skin damage Effects 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 210000003754 fetus Anatomy 0.000 description 2
- 210000002216 heart Anatomy 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000008176 lyophilized powder Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 206010004053 Bacterial toxaemia Diseases 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102000004308 Carboxylic Ester Hydrolases Human genes 0.000 description 1
- 108090000863 Carboxylic Ester Hydrolases Proteins 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
- 239000004473 Threonine Substances 0.000 description 1
- 208000013222 Toxemia Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000006136 alcoholysis reaction Methods 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 208000026500 emaciation Diseases 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 210000001097 facial muscle Anatomy 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 229940102465 ginger root Drugs 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 230000000512 lipotoxic effect Effects 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000008557 oxygen metabolism Effects 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 210000005059 placental tissue Anatomy 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 235000004400 serine Nutrition 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000008521 threonine Nutrition 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000001841 zingiber officinale Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Pregnancy & Childbirth (AREA)
- Virology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a composition for expelling toxin, beautifying and eliminating dampness, a preparation method and a capsule, and relates to the technical field of traditional Chinese medicines. The composition comprises the following raw materials in parts by weight: 40-50 parts of sheep placenta, 550 parts of poria cocos, 800 parts of ginger 700-. The composition takes Poria and radix kansui as principal drugs, and has effects of clearing away heat and toxic materials, promoting diuresis, eliminating dampness, relieving swelling and pain, removing food retention, relieving constipation, purging pathogenic water, resolving hard mass, and removing water; and ginger is taken as the ministerial drug, so that the effects of relieving exterior syndrome and dispelling cold, warming middle-jiao and arresting vomiting, warming lung and relieving cough, inhibiting bacteria and preventing infection are achieved; the sheep placenta is used for regulating endocrine dyscrasia of human body, enhancing immunity of human body and promoting hematopoiesis, and lipase is added to treat symptoms such as general weakness, sallow complexion, dizziness, tinnitus, palpitation and the like caused by anemia, so that the use value of the composition can be improved.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a composition for expelling toxin, beautifying and removing dampness, a preparation method and a capsule.
Background
The epidermis layer of the skin comprises a horny layer, a granular layer, a spinous layer and a basal layer, the dermis layer is arranged below the epidermis layer, a microvascular network is distributed in the dermis layer, and the microvascular network in the epidermis layer, the dermis layer and the dermis layer forms a microcirculation system of the skin.
The skin cells obtain moisture, oxygen and various nutrients given by skin care products through microcirculation, the moisture, the oxygen and the various nutrients are permeated into a dermis layer through an epidermis layer, the skin cells are absorbed by microvessels in the dermis layer and then are conveyed out to be provided for a basal layer as growth nutrients of new cells, the new cells are matured more and more along with the lapse of time, move to the outer layer of the epidermis, become spiny cells, become granular cells and finally become keratinocytes, and the skin microcirculation is formed.
When the microcirculation of facial skin is blocked, the blood circulation and blood oxygen metabolism of the face can be affected, endotoxins such as lipotoxicity, toxemia, wind-cold-damp-heat toxin, melanin and the like are easily accumulated on the surface layer of the skin, the function of the skin is damaged, the protection capability and the regulation capability of the skin on the body are reduced, and therefore, the skin cannot adapt to the change of internal and external environments, and the appearance overall conditions such as color, luster, form, texture and the like are changed, and the symptoms such as dark and bluish complexion, full face acne, red swelling and ulceration, exudation and scabbing, facial muscle wrinkle deepening, contour sagging, rough skin, yellowish or grayish yellow skin, pigmented spots and the like are presented.
Therefore, aiming at the above, the composition for expelling toxin, beautifying and dehumidifying is significant.
Disclosure of Invention
The invention aims to provide a composition for expelling toxin, beautifying and dehumidifying, which not only has the effects of expelling toxin, beautifying, dehumidifying and dredging collaterals, but also has better treatment effect on various skin diseases, such as psoriasis, eczema, chloasma, yellow face gray and dark spots and the like.
The invention also aims to provide a preparation method of the composition for expelling toxin, beautifying and dehumidifying, which can extract effective components in raw materials, simultaneously avoid the damage and volatilization loss of the effective components and achieve better preparation effect.
The invention also aims to provide the toxin-expelling face-nourishing and dampness-removing capsule which can cover the pungent taste of the composition, is low in taking difficulty, is convenient to carry, store and transport and is more convenient.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
In a first aspect, the application provides a composition for detoxifying, beautifying and dehumidifying, which comprises the following raw materials in parts by weight: 40-50 parts of sheep placenta, 550 parts of poria cocos, 800 parts of ginger 700, 45-55 parts of euphorbia kansui and 70-80 parts of lipase.
In a second aspect, the application provides a preparation method of the composition for expelling toxin, beautifying and removing dampness, which mainly comprises the following steps: decocting Poria with water for 3 times, filtering respectively, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; drying the extract and then crushing to prepare first medicinal powder; pulverizing rhizoma Zingiberis recens, decocting in water for 1.5-2.5 h, filtering to obtain rhizoma Zingiberis recens liquid, and concentrating to obtain extract II; drying the second extract and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition.
In a third aspect, the application provides a toxin-expelling, skin-beautifying and dehumidifying capsule, wherein the composition prepared by the preparation method of the toxin-expelling, skin-beautifying and dehumidifying composition is filled into a hard capsule shell to prepare the toxin-expelling, skin-beautifying and dehumidifying capsule.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
firstly, the application provides a composition for expelling toxin, beautifying and dehumidifying, which takes tuckahoe and euphorbia kansui as monarch drugs and achieves the effects of clearing away heat and toxic materials, promoting diuresis and excreting dampness, relieving swelling and pain, breaking stagnation and relaxing bowels, purging water and removing retained fluid, relieving swelling and resolving masses and drastically removing retained fluid; and ginger is taken as the ministerial drug, so that the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, preventing vomiting, warming lung, relieving cough, inhibiting bacteria and preventing infection are achieved; the sheep placenta is used for regulating endocrine dyscrasia of human body, enhancing immunity of human body and promoting hematopoiesis, and lipase is added to treat symptoms such as general weakness, sallow complexion, dizziness, tinnitus, palpitation and the like caused by anemia, so that the use value of the composition can be improved.
Secondly, the application provides a preparation method of the composition for expelling toxin, beautifying and dehumidifying, so that the effective ingredients in the raw materials can be extracted, meanwhile, the damage and volatilization loss of the effective ingredients can be avoided, and the preparation effect is good.
Thirdly, the toxin expelling, face nourishing and dampness removing capsule prepared by the preparation method can cover the pungent taste of the composition, is low in taking difficulty, and meanwhile is convenient to carry, store and transport and higher in convenience.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are conventional products which are not indicated by manufacturers and are commercially available.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
In a first aspect, the application provides a composition for detoxifying, beautifying and dehumidifying, which comprises the following raw materials in parts by weight: 40-50 parts of sheep placenta, 550 parts of poria cocos, 800 parts of ginger 700, 45-55 parts of euphorbia kansui and 70-80 parts of lipase. The specific effects of the raw materials are as follows:
Sheep placenta: the sheep placenta is a tissue responsible for exchanging blood and nutrients of a mother body and a fetus when the mother sheep breeds the fetus, can generate more active substances, and is easy to absorb because the sheep placenta is close to human placenta tissue. In addition, the sheep placenta has sweet and warm nature, has the effects of tonifying qi and deficiency, warming the middle warmer and the lower warmer, regulating and tonifying kidney deficiency and emaciation, and also has the effects of nourishing blood and soothing the nerves, enlarging skin, prolonging life and the like. Meanwhile, the sheep placenta is rich in various amino acids, such as aspartic acid, threonine, serine, glutamic acid, glycine, tyrosine, phenylalanine, arginine and the like, and also rich in various elements such as potassium, sodium, calcium, magnesium, iron, manganese, zinc and the like. Therefore, when the composition is used as one of the raw materials of the composition, the composition can supplement deficiency and thin, strengthen the muscles and bones, moisten the skin and beautify the face, and increase essence and marrow, thereby improving the use value of the composition.
Tuckahoe, poria cocos: poria is also called Yuling, Fu Ling, Wanling Gui, etc., has sweet and mild nature and flavor, has the effects of clearing heart, lung, spleen and kidney channels, promoting diuresis, eliminating dampness, invigorating spleen and calming heart, and is mainly used for treating symptoms such as edema, oliguria, phlegm and fluid retention, dizziness and palpitation, spleen deficiency, poor appetite, loose stool, diarrhea, uneasiness, palpitation, insomnia, etc.
Ginger: the ginger is also called as ginger root, Bai pungent cloud, hooked finger, Yidilong, Yan Liang Xiaozi, pungent and warm in nature and flavor, enters lung, spleen and stomach channels, has the efficacies of relieving exterior syndrome and dispelling cold, warming middle-jiao and preventing vomiting, warming lung and relieving cough, detoxifying and the like, and is mainly used for treating wind-cold type cold, spleen and stomach cold syndrome, stomach cold vomiting, lung cold cough, fish and crab poison relieving and other diseases.
And (3) kansui root: it is named as Sutian, Ganze, Gansu, Ling Gao, Ganze, Baize, Gui Chong and Ling Zi, has bitter taste and cold property, and has the functions of purging water, eliminating swelling, etc. and is used for treating edema, ascites, retained fluid, chest forming, epilepsy, cough and asthma, etc.
And (2) lipase: lipases are belonging to the class of carboxyl ester hydrolases and are capable of stepwise hydrolysing triglycerides into glycerol and fatty acids. Lipases include phosphatases, alcoholases and carboxylesterases, which catalyze the hydrolysis, alcoholysis, esterification, transesterification of triacylglycerides and other water-insoluble esters and the reverse synthesis of esters.
In conclusion, the composition takes the poria cocos and the euphorbia kansui as monarch drugs, and achieves the effects of clearing away heat and toxic materials, inducing diuresis and excreting dampness, relieving swelling and pain, breaking accumulation and relaxing bowels, purging water and expelling retained fluid, relieving swelling and resolving masses and removing water drastically; and ginger is taken as the ministerial drug, so that the effects of relieving exterior syndrome and dispelling cold, warming middle-jiao and arresting vomiting, warming lung and relieving cough, inhibiting bacteria and preventing infection are achieved; the sheep placenta is used for regulating endocrine dyscrasia of human body, enhancing immunity of human body and promoting hematopoiesis, and lipase is added to treat symptoms such as general weakness, sallow complexion, dizziness, tinnitus, palpitation and the like caused by anemia, so that the use value of the composition can be improved.
In the application, the composition comprises the following raw materials in parts by weight: 45 parts of sheep placenta, 500 parts of tuckahoe, 750 parts of ginger, 50 parts of euphorbia kansui and 75 parts of lipase. In the proportion, the raw material content is scientific and reasonable, the compatibility effect is better, and the using effect is better.
In a second aspect, the application provides a preparation method of a composition for expelling toxin, beautifying and removing dampness, which comprises the following steps: the method mainly comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; drying the extract, and then crushing to obtain medicinal powder I; pulverizing rhizoma Zingiberis recens, decocting in water for 1.5-2.5 h, filtering to obtain rhizoma Zingiberis recens liquid, and concentrating to obtain extract II; drying the second extract and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition.
In the application, when the poria cocos is decocted for 3 times, the volume ratio of the water consumption for the first decoction, the water consumption for the second decoction and the water consumption for the third decoction is (4.5-5.5):4: 3.
In the application, when the poria cocos is decocted for 3 times, the single decoction time is 1.8-2.2 h.
In the application, the ginger liquid is concentrated in a slow fire decoction manner in the concentration process.
In the application, the ginger liquid is decocted and concentrated, then mixed with 90 voL% -95 voL% of ethanol, precipitated and filtered to obtain filtrate, and the filtrate is refluxed and ethanol is recovered to obtain the second extract.
In the application, the second extract is dried at the temperature of below 80 ℃, and is crushed to prepare second medicinal powder.
In the application, the sheep placenta powder is prepared by a freeze drying mode.
Specifically, fresh ginger is extracted by a water decoction method, and water-soluble components in the fresh ginger can be extracted, so that the effects of treating skin diseases and removing moisture in a patient are achieved.
In addition, lipase and sheep placenta lyophilized powder (lyophilized sheep placenta powder) can be mixed with powder I, powder II and radix kansui powder, and after mixing powder I, powder II and radix kansui powder and drying, lipase and sheep placenta lyophilized powder can be added thereto, so that the prepared composition does not need to be dried again, thereby preventing the effective components from being damaged.
Therefore, the preparation method can effectively improve the dissolution amount of the effective components, can avoid the effective components from being damaged by high temperature or other factors, and has good preparation effect.
In a third aspect, the application provides a toxin-expelling, skin-beautifying and dehumidifying capsule, wherein the composition prepared by the preparation method of the toxin-expelling, skin-beautifying and dehumidifying composition is filled into a hard capsule shell to prepare the toxin-expelling, skin-beautifying and dehumidifying capsule. The capsule can cover the pungent taste of the composition, is low in administration difficulty, and is convenient to carry, store and transport and high in convenience.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment aims to provide a composition for expelling toxin, beautifying and dehumidifying, which comprises the following raw materials: 45g of sheep placenta, 500g of tuckahoe, 750g of ginger, 50g of euphorbia kansui and 75g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein the volume ratio of the water consumption for the first decoction to the water consumption for the second decoction to the water consumption for the third decoction is 5:4:3, and the time for single decoction is 2 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 2 hr, filtering to obtain rhizoma Zingiberis recens liquid, concentrating the rhizoma Zingiberis recens liquid with slow fire, mixing with 95 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 180 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
Example 2
The embodiment aims to provide a composition for expelling toxin, beautifying and dehumidifying, which comprises the following raw materials: 40g of sheep placenta, 450g of tuckahoe, 700g of ginger, 45g of euphorbia kansui and 70g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein, the volume ratio of the water consumption for the first decoction, the water consumption for the second decoction and the water consumption for the third decoction is 4.5:4:3, and the time for single decoction is 1.8 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 1.5h, filtering to obtain rhizoma Zingiberis recens liquid, concentrating the rhizoma Zingiberis recens liquid with slow fire, mixing with 90 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 130 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
Example 3
The embodiment aims to provide a composition for expelling toxin, beautifying and dehumidifying, which comprises the following raw materials: 50g of sheep placenta, 550g of tuckahoe, 800g of ginger, 55g of euphorbia kansui and 80g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein, the volume ratio of the water consumption for the first decoction, the water consumption for the second decoction and the water consumption for the third decoction is 5.5:4:3, and the time for single decoction is 2.2 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 2.5h, filtering to obtain rhizoma Zingiberis recens liquid, concentrating with slow fire, mixing with 93 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 200 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
Example 4
The embodiment aims to provide a composition for expelling toxin, beautifying and dehumidifying, which comprises the following raw materials: 43g of sheep placenta, 48g of poria cocos, 7350g of ginger, 48g of euphorbia kansui and 73g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein the volume ratio of the water consumption for the first decoction to the water consumption for the second decoction to the water consumption for the third decoction is 4.7:4:3, and the time for single decoction is 1.9 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 1.7h, filtering to obtain rhizoma Zingiberis recens liquid, concentrating the rhizoma Zingiberis recens liquid with slow fire, mixing with 95 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 150 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
Example 5
The present embodiment aims to provide a toxin-expelling, skin-nourishing and dampness-removing composition, which includes the following raw materials: 48g of sheep placenta, 530g of poria cocos, 780g of ginger, 53g of euphorbia kansui and 78g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein the volume ratio of the water consumption for the first decoction to the water consumption for the second decoction to the water consumption for the third decoction is 5.3:4:3, and the time for single decoction is 21 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 2.3h, filtering to obtain rhizoma Zingiberis recens liquid, concentrating with slow fire, mixing with 95 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 160 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
Example 6
The present embodiment aims to provide a toxin-expelling, skin-nourishing and dampness-removing composition, which includes the following raw materials: 45g of sheep placenta, 500g of poria cocos, 750g of ginger, 50g of euphorbia kansui and 75g of lipase.
The preparation method of the composition comprises the following steps:
decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating the medicinal liquid to obtain extract I; wherein the volume ratio of the water consumption for the first decoction to the water consumption for the second decoction to the water consumption for the third decoction is 5:4:3, and the time for single decoction is 2 h. Drying the extract and then crushing to obtain first medicinal powder;
pulverizing rhizoma Zingiberis recens, decocting in water for 2 hr, filtering to obtain rhizoma Zingiberis recens liquid, concentrating the rhizoma Zingiberis recens liquid with slow fire, mixing with 95 voL% ethanol, precipitating, filtering to obtain filtrate, refluxing the filtrate, recovering ethanol, and making into extract II; drying the second extract at the temperature of below 80 ℃, and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, radix kansui powder, lipase and placenta caprae seu ovis powder to obtain the composition. Wherein the particle diameters of the first medicinal powder, the second medicinal powder and the kansui root powder are respectively 180 meshes, and the sheep placenta powder is prepared by a freeze drying mode.
The composition is filled into a hard capsule shell to prepare the toxin-expelling, face-nourishing and dampness-removing capsule.
Effects of the invention
1. Quality detection
(1) The shape is as follows: the composition is brown yellow and pink powder, has sweet and pungent taste, spicy tongue feeling, and ginger flavor;
(2) the composition prepared in example 1 is ground, 20mL of ethanol is added for dissolution, 2mL of filtrate is taken, and a few drops of 2% ferric trichloride ethanol solution are added into the filtrate, so that the solution is brown yellow.
Taking 2mL of brown yellow solution, adding 1mL of hydrochloric acid, adding 1g of iron powder, oscillating, and filtering to obtain yellowish solution.
According to the quality detection, the detection result accords with the relevant regulations of the pharmacopoeia of the people's republic of China on the capsule item, and the quality is qualified.
2. Trial effect
In the application, the capsule prepared in the embodiment 6 is taken as a trial product, after trial statistics, 100 patients in the data system are selected at random, and the effective rate, the significant efficiency and the inefficiency are counted, wherein the effective rate is 100%, the significant efficiency is 95%, and the inefficiency is zero.
The curative effect is judged as follows: the curative effect is graded by Samuelson 9 degrees, and the effective grade is that the skin damage is graded and reduced by more than 3 grades, the obvious effect is that the skin damage is graded and reduced by more than 1-2 grades, and the ineffective grade is that the skin damage is not changed.
Typical cases are specifically as follows:
one volunteer, a certain segment, 49 years old, Shanxi people suffer from skin eczema in 2012, go to medical treatment and do not heal, and hormone medicines are used in 2016 until the condition is aggravated in the treatment process, specifically expressed as hormone signs and hormone faces; the patient took the capsule prepared in example 6 in 2021, 4 months, after two months, the disease was gradually cured, and no recurrence occurred after revisit.
Second volunteer, Zhao Yi, 21 years old, Beijing, student, after 2015 had acne, the disease aggravated by drug abuse, especially by hormone drugs, recommended by sufferers, after 2015 took the capsule prepared in example 6, after a half month, the disease gradually healed, and after revisit, the disease did not recur.
The disease condition of a third volunteer, a certain volunteer, 22 years old and Shanxi, gradually worsened after suffering from acne in 2014, and changed into hormonal acne in the treatment process, and after introduction by colleagues, the capsule prepared in example 6 is taken in 7 months in 2021, and the disease is cured after two months.
In conclusion, the application provides a composition for expelling toxin, beautifying and dehumidifying, which takes tuckahoe and euphorbia kansui as monarch drugs and achieves the effects of clearing away heat and toxic materials, promoting diuresis and excreting dampness, relieving swelling and pain, breaking stagnation and relaxing bowels, purging water and expelling retained fluid, relieving swelling and resolving masses and drastically expelling water; and ginger is taken as the ministerial drug, so that the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, preventing vomiting, warming lung, relieving cough, inhibiting bacteria and preventing infection are achieved; the sheep placenta is used for regulating endocrine dyscrasia of human body, enhancing immunity of human body and promoting hematopoiesis, and lipase is added to treat symptoms such as general weakness, sallow complexion, dizziness, tinnitus, palpitation and the like caused by anemia, so that the use value of the composition can be improved. The preparation method of the composition can extract the effective components in the raw materials, can avoid the damage and volatilization loss of the effective components, and has good preparation effect. The toxin-expelling, face-beautifying and dampness-removing capsule prepared by the preparation method can cover the pungent taste of the composition, is low in taking difficulty, and meanwhile is convenient to carry, store and transport and high in convenience.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. The composition for expelling toxin, beautifying and dehumidifying is characterized by comprising the following raw materials in parts by weight: 40-50 parts of sheep placenta, 550 parts of poria cocos, 800 parts of ginger 700, 45-55 parts of euphorbia kansui and 70-80 parts of lipase.
2. The composition for expelling toxins, beautifying and dehumidifying as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 45 parts of sheep placenta, 500 parts of tuckahoe, 750 parts of ginger, 50 parts of euphorbia kansui and 75 parts of lipase.
3. A method for preparing a composition for expelling toxins, nourishing the face and removing dampness as claimed in claim 1 or 2, characterized by comprising the following steps: decocting Poria with water for 3 times, filtering, mixing filtrates to obtain medicinal liquid, and concentrating to obtain extract I; drying the extract and then crushing to obtain first medicinal powder; pulverizing rhizoma Zingiberis recens, decocting in water for 1.5-2.5 h, filtering to obtain rhizoma Zingiberis recens liquid, and concentrating to obtain extract II; drying the second extract and then crushing to obtain second medicinal powder; mixing the first powder, the second powder, the kansui root powder, the lipase and the sheep placenta powder to obtain the composition.
4. The preparation method of claim 3, wherein when Poria cocos wolf is decocted 3 times, the volume ratio of the water consumption for the first decoction, the water consumption for the second decoction and the water consumption for the third decoction is (4.5-5.5):4: 3.
5. The preparation method according to claim 3, wherein the time for decocting Poria cocos wolf for 3 times is 1.8h-2.2 h.
6. The preparation method according to claim 3, wherein the ginger solution is concentrated by decocting with slow fire during the concentration process.
7. The preparation method of claim 6, wherein the ginger solution is decocted and concentrated, then mixed with 90 voL% -95 voL% ethanol, precipitated, filtered to obtain a filtrate, and the filtrate is refluxed and ethanol is recovered to obtain the second extract.
8. The preparation method of claim 3, wherein the second extract is dried at a temperature below 80 ℃, and is pulverized to obtain the second powder.
9. The method of claim 3, wherein said sheep placenta powder is prepared by freeze-drying.
10. A toxin expelling, face nourishing and dampness removing capsule, which is characterized in that the composition prepared by the preparation method of the toxin expelling, face nourishing and dampness removing composition of any one of claims 3 to 9 is filled into a hard capsule shell to prepare the toxin expelling, face nourishing and dampness removing capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210550220.6A CN114748613A (en) | 2022-05-20 | 2022-05-20 | Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210550220.6A CN114748613A (en) | 2022-05-20 | 2022-05-20 | Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule |
Publications (1)
Publication Number | Publication Date |
---|---|
CN114748613A true CN114748613A (en) | 2022-07-15 |
Family
ID=82335595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202210550220.6A Pending CN114748613A (en) | 2022-05-20 | 2022-05-20 | Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114748613A (en) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102309659A (en) * | 2011-05-19 | 2012-01-11 | 大连九羊食品有限公司 | Traditional Chinese medicine (TCM) capsule containing sheep placenta and processing method thereof |
CN102641397A (en) * | 2012-03-30 | 2012-08-22 | 常熟市海虞茶叶有限公司 | Sheep placenta-containing composite capsule and preparation method thereof |
CN105056191A (en) * | 2015-08-25 | 2015-11-18 | 黄名珠 | Traditional Chinese medicine for treating pompholyx |
CN107432341A (en) * | 2017-07-29 | 2017-12-05 | 宇琪 | The preparation method of the compound jasmine tea of the root of gansui |
CN109793881A (en) * | 2019-03-20 | 2019-05-24 | 杭州彼心生物科技有限公司 | A kind of toxin-expelling and face nourishing Chinese herbs paste and preparation method thereof and application method |
CN111249393A (en) * | 2020-03-23 | 2020-06-09 | 中科花鹿农业发展有限公司 | Deer placenta nutrient soft capsule for enriching blood and resisting aging and preparation method thereof |
CN112402567A (en) * | 2020-11-26 | 2021-02-26 | 四川烨哼健康药房有限公司 | Medicinal health wine with qi and blood tonifying, beauty maintaining and young keeping functions and preparation method thereof |
-
2022
- 2022-05-20 CN CN202210550220.6A patent/CN114748613A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102309659A (en) * | 2011-05-19 | 2012-01-11 | 大连九羊食品有限公司 | Traditional Chinese medicine (TCM) capsule containing sheep placenta and processing method thereof |
CN102641397A (en) * | 2012-03-30 | 2012-08-22 | 常熟市海虞茶叶有限公司 | Sheep placenta-containing composite capsule and preparation method thereof |
CN105056191A (en) * | 2015-08-25 | 2015-11-18 | 黄名珠 | Traditional Chinese medicine for treating pompholyx |
CN107432341A (en) * | 2017-07-29 | 2017-12-05 | 宇琪 | The preparation method of the compound jasmine tea of the root of gansui |
CN109793881A (en) * | 2019-03-20 | 2019-05-24 | 杭州彼心生物科技有限公司 | A kind of toxin-expelling and face nourishing Chinese herbs paste and preparation method thereof and application method |
CN111249393A (en) * | 2020-03-23 | 2020-06-09 | 中科花鹿农业发展有限公司 | Deer placenta nutrient soft capsule for enriching blood and resisting aging and preparation method thereof |
CN112402567A (en) * | 2020-11-26 | 2021-02-26 | 四川烨哼健康药房有限公司 | Medicinal health wine with qi and blood tonifying, beauty maintaining and young keeping functions and preparation method thereof |
Non-Patent Citations (4)
Title |
---|
吕丹等: "不同阶段美容保健食品功能声称演变与问题分析", 《中华中医药杂志》 * |
李志忠等: "羊胎盘肽研究与利用进展", 《食品工业科技》 * |
薛磊主编: "老祖宗留下的抗衰老排毒养颜经", 天津科学技术出版社 * |
陈明岭等: "《皮肤病常用中药药理及临床》", 31 October 2017 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101648002A (en) | Medicinal composition for treating skin injury and ulcer and application thereof | |
CN103463297B (en) | A kind of Chinese medicine composition for the treatment of eczema scrotum and its production and use | |
CN102512615B (en) | Traditional Chinese medicinal composition used for cancer recovery stage | |
CN110193064A (en) | A kind of Chinese medicine fecula application and preparation method thereof for pain caused by cancer | |
CN114748613A (en) | Composition for expelling toxin, beautifying and eliminating dampness, preparation method and capsule | |
CN105125792A (en) | Traditional Chinese medicinal decoction for treating female mastitis and preparation method of decoction | |
CN101647985B (en) | Medicament composition for treating psoriasis | |
CN102028831B (en) | Traditional Chinese medicine composition for treating tumors or cancers and preparation method thereof | |
CN113456778A (en) | Composition for improving energy and preparation method thereof | |
CN102626471B (en) | Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration | |
CN111084878A (en) | Biological medicine and medical total nutrient food for lung and respiratory system diseases and preparation method thereof | |
CN103285174A (en) | Nursing ointment for repairing scars | |
CN108185055A (en) | A kind of health preserving tea and preparation method thereof | |
CN100423764C (en) | Tumor-treating oral Chinese medicine composition | |
CN106728565A (en) | A kind of scorpio medicine vinegar liquid and preparation method thereof | |
CN1686476A (en) | Chinese medicinal preparation for treating cancer and tumor and preparation method thereof | |
CN107007739B (en) | Composition for improving or treating radiation oropharyngeal mucositis and preparation method and application thereof | |
CN103637349B (en) | Functional beverage capable of removing dampness and tonifying deficiency and preparation method thereof | |
CN104940710A (en) | Traditional Chinese medicine Kangning composition comprising soncretio silicea bambusae for treating epilepsy, and preparation method thereof | |
CN106074904B (en) | A kind of pharmaceutical composition for the treatment of of acute radiation oral mucositis and preparation method thereof | |
CN110742973A (en) | Dampness eliminating tea and preparation method thereof | |
CN115154562A (en) | A topical composition for treating cancer, and its preparation method | |
CN104352891A (en) | Traditional Chinese medicine preparation for treating angina | |
CN111789903A (en) | Pharmaceutical composition for treating urethral cancer and preparation method thereof | |
CN114732882A (en) | Traditional Chinese medicine composition and preparation method and application thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220715 |