CN113616565A - 芍药根提取物、含其皮肤外用剂及其制备方法和应用 - Google Patents
芍药根提取物、含其皮肤外用剂及其制备方法和应用 Download PDFInfo
- Publication number
- CN113616565A CN113616565A CN202110867560.7A CN202110867560A CN113616565A CN 113616565 A CN113616565 A CN 113616565A CN 202110867560 A CN202110867560 A CN 202110867560A CN 113616565 A CN113616565 A CN 113616565A
- Authority
- CN
- China
- Prior art keywords
- skin
- active ingredient
- skin external
- root extract
- sodium hyaluronate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 54
- 229940084032 paeonia lactiflora root extract Drugs 0.000 title claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 60
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 42
- 241000736199 Paeonia Species 0.000 claims abstract description 38
- 238000000034 method Methods 0.000 claims abstract description 34
- 230000000694 effects Effects 0.000 claims abstract description 31
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 28
- 230000003020 moisturizing effect Effects 0.000 claims abstract description 16
- 230000008591 skin barrier function Effects 0.000 claims abstract description 13
- 239000007788 liquid Substances 0.000 claims abstract description 11
- 230000008569 process Effects 0.000 claims abstract description 9
- 206010061218 Inflammation Diseases 0.000 claims abstract description 6
- 239000002904 solvent Substances 0.000 claims abstract description 4
- 239000004480 active ingredient Substances 0.000 claims description 37
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 36
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 36
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 36
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 29
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 22
- 239000003795 chemical substances by application Substances 0.000 claims description 19
- 230000001877 deodorizing effect Effects 0.000 claims description 13
- 239000011259 mixed solution Substances 0.000 claims description 13
- 238000005119 centrifugation Methods 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- 235000011187 glycerol Nutrition 0.000 claims description 11
- 238000001179 sorption measurement Methods 0.000 claims description 10
- 239000002562 thickening agent Substances 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- 239000003963 antioxidant agent Substances 0.000 claims description 6
- 230000003078 antioxidant effect Effects 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 5
- 238000000967 suction filtration Methods 0.000 claims description 5
- 206010015150 Erythema Diseases 0.000 claims description 4
- 238000004042 decolorization Methods 0.000 claims description 4
- 238000004332 deodorization Methods 0.000 claims description 4
- 230000001603 reducing effect Effects 0.000 claims description 4
- 230000008439 repair process Effects 0.000 claims description 4
- 238000005374 membrane filtration Methods 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 3
- 239000001054 red pigment Substances 0.000 claims description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 2
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 claims description 2
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 2
- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 230000004054 inflammatory process Effects 0.000 claims description 2
- 239000000230 xanthan gum Substances 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- 229940082509 xanthan gum Drugs 0.000 claims description 2
- 235000010493 xanthan gum Nutrition 0.000 claims description 2
- 239000002781 deodorant agent Substances 0.000 claims 5
- 230000007760 free radical scavenging Effects 0.000 claims 3
- 210000003205 muscle Anatomy 0.000 abstract description 8
- 239000003960 organic solvent Substances 0.000 abstract description 7
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 3
- 230000000638 stimulation Effects 0.000 abstract description 3
- 230000000052 comparative effect Effects 0.000 description 19
- 238000012360 testing method Methods 0.000 description 18
- 239000000047 product Substances 0.000 description 17
- 230000037307 sensitive skin Effects 0.000 description 15
- 239000000463 material Substances 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 11
- 230000002757 inflammatory effect Effects 0.000 description 8
- 239000002994 raw material Substances 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 239000006228 supernatant Substances 0.000 description 7
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 244000236658 Paeonia lactiflora Species 0.000 description 6
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 6
- 241001106477 Paeoniaceae Species 0.000 description 6
- 230000036571 hydration Effects 0.000 description 6
- 238000006703 hydration reaction Methods 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 239000013641 positive control Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 102000004889 Interleukin-6 Human genes 0.000 description 4
- 108090001005 Interleukin-6 Proteins 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 4
- 229960003957 dexamethasone Drugs 0.000 description 4
- 239000003085 diluting agent Substances 0.000 description 4
- 239000006185 dispersion Substances 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 description 3
- 102000000589 Interleukin-1 Human genes 0.000 description 3
- 108010002352 Interleukin-1 Proteins 0.000 description 3
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 3
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 239000013592 cell lysate Substances 0.000 description 2
- 239000006285 cell suspension Substances 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005265 energy consumption Methods 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 229960003444 immunosuppressant agent Drugs 0.000 description 2
- 239000003018 immunosuppressive agent Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 230000037067 skin hydration Effects 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- MIDXCONKKJTLDX-UHFFFAOYSA-N 3,5-dimethylcyclopentane-1,2-dione Chemical compound CC1CC(C)C(=O)C1=O MIDXCONKKJTLDX-UHFFFAOYSA-N 0.000 description 1
- GOZMBJCYMQQACI-UHFFFAOYSA-N 6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one;dihydrochloride Chemical compound Cl.Cl.C=1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC(C1=CC=CC=C11)=CN1C1=CC=CC(C(F)(F)F)=C1 GOZMBJCYMQQACI-UHFFFAOYSA-N 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 206010004950 Birth mark Diseases 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 238000008157 ELISA kit Methods 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- 208000002260 Keloid Diseases 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- 244000245214 Mentha canadensis Species 0.000 description 1
- 235000016278 Mentha canadensis Nutrition 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 208000009077 Pigmented Nevus Diseases 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 235000013736 caramel Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 108010036027 erythrogenin Proteins 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000007813 immunodeficiency Effects 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 210000001117 keloid Anatomy 0.000 description 1
- 208000002741 leukoplakia Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 238000003828 vacuum filtration Methods 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical & Material Sciences (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
原料 | 重量份数(份) |
实施例1制得的芍药根提取物 | 97.8 |
高分子透明质酸钠,>180W | 0.1 |
透明质酸钠,100-180W | 0.05 |
低分子透明质酸钠,20-40W | 0.05 |
甘油 | 2 |
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110867560.7A CN113616565A (zh) | 2021-07-30 | 2021-07-30 | 芍药根提取物、含其皮肤外用剂及其制备方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110867560.7A CN113616565A (zh) | 2021-07-30 | 2021-07-30 | 芍药根提取物、含其皮肤外用剂及其制备方法和应用 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113616565A true CN113616565A (zh) | 2021-11-09 |
Family
ID=78381588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110867560.7A Pending CN113616565A (zh) | 2021-07-30 | 2021-07-30 | 芍药根提取物、含其皮肤外用剂及其制备方法和应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113616565A (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112516025A (zh) * | 2020-12-14 | 2021-03-19 | 深圳市悦青春健康科技有限公司 | 一种具有透皮吸收功效的植物提取组合物乳霜及其制备方法 |
CN114010563A (zh) * | 2021-11-30 | 2022-02-08 | 上海宜侬生物科技有限公司 | 一个具有焕亮抗老作用的成分及应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004339142A (ja) * | 2003-05-15 | 2004-12-02 | Kanebo Ltd | 皮膚化粧料 |
KR20080080792A (ko) * | 2007-03-02 | 2008-09-05 | 류효창 | 생약추출물을 이용한 발모기능성 비누 및 그 제조방법 |
CN101759737A (zh) * | 2009-10-22 | 2010-06-30 | 南京泽朗医药科技有限公司 | 一种芍药苷的制备方法 |
CN106667854A (zh) * | 2017-03-02 | 2017-05-17 | 刘金凤 | 一种能够加快破损皮肤再生的保湿美白面膜 |
CN108078829A (zh) * | 2018-01-12 | 2018-05-29 | 广州赛莱拉干细胞科技股份有限公司 | 绵毛多管藻提取物的护肤液 |
CN108451806A (zh) * | 2018-03-12 | 2018-08-28 | 广州市泛海精细化工有限公司 | 一种天然抗敏保湿组合物及其制备方法和应用 |
-
2021
- 2021-07-30 CN CN202110867560.7A patent/CN113616565A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004339142A (ja) * | 2003-05-15 | 2004-12-02 | Kanebo Ltd | 皮膚化粧料 |
KR20080080792A (ko) * | 2007-03-02 | 2008-09-05 | 류효창 | 생약추출물을 이용한 발모기능성 비누 및 그 제조방법 |
CN101759737A (zh) * | 2009-10-22 | 2010-06-30 | 南京泽朗医药科技有限公司 | 一种芍药苷的制备方法 |
CN106667854A (zh) * | 2017-03-02 | 2017-05-17 | 刘金凤 | 一种能够加快破损皮肤再生的保湿美白面膜 |
CN108078829A (zh) * | 2018-01-12 | 2018-05-29 | 广州赛莱拉干细胞科技股份有限公司 | 绵毛多管藻提取物的护肤液 |
CN108451806A (zh) * | 2018-03-12 | 2018-08-28 | 广州市泛海精细化工有限公司 | 一种天然抗敏保湿组合物及其制备方法和应用 |
Non-Patent Citations (1)
Title |
---|
李兴广, 人民军医出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112516025A (zh) * | 2020-12-14 | 2021-03-19 | 深圳市悦青春健康科技有限公司 | 一种具有透皮吸收功效的植物提取组合物乳霜及其制备方法 |
CN114010563A (zh) * | 2021-11-30 | 2022-02-08 | 上海宜侬生物科技有限公司 | 一个具有焕亮抗老作用的成分及应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN113616565A (zh) | 芍药根提取物、含其皮肤外用剂及其制备方法和应用 | |
CN107616956A (zh) | 一种芦荟护肤组合物及其制备方法 | |
CN105326730B (zh) | 一种含中草药提取物的祛痘组合物及其制备方法 | |
CN106265164B (zh) | 具有生发、头皮修护、保湿功效的组合物及其制备方法 | |
CN106389219A (zh) | 一种具有美白祛斑作用的外用中药组合物及护肤制剂 | |
CN104622740B (zh) | 娑罗子提取物在制备药物化妆品中的用途 | |
CN113398053A (zh) | 一种具有舒敏保湿功效的润肤组合物的制备方法与应用 | |
KR102330465B1 (ko) | 소나무 수피 추출물을 포함하는 부종완화, 셀룰라이트 감소, 체지방 분해 및 혈액순환 촉진 효능을 갖는 피부용 화장료 조성물 및 이를 이용한 피부용 크림 | |
CN107320565A (zh) | 一种具有抗敏感功效的中药组合物及其制备方法和应用 | |
CN108309873B (zh) | 赋活均衡调理精华液 | |
CN107260612B (zh) | 祛除黄褐斑组合物、应用、复合制剂及制备方法 | |
CN111643430A (zh) | 一种协同激光治疗黑眼圈的眼部精华及其制备方法 | |
CN106389305A (zh) | 凝肌乳 | |
CN111202821B (zh) | 具有舒敏抗炎功效的中药提取物及其制备方法与应用 | |
CN110772554B (zh) | 一种用于治疗黄褐斑的透明质酸钠凝胶及其制备方法 | |
CN110507712B (zh) | 一种外用治疗关节炎的白头翁提取物及其制备方法 | |
CN110897971B (zh) | 一种含卷柏素的护发清洁组合物及其制备方法 | |
CN113456555A (zh) | 牡丹花提取物、含其皮肤外用剂及其制备方法和应用 | |
CN115025027A (zh) | 一种生物因子睫毛滋养液 | |
CN113440457A (zh) | 一种白及组方及其制备方法 | |
CN113278462B (zh) | 一种芝麻香油的提取方法及在皮肤修复领域的应用 | |
CN110407952B (zh) | 一种精制植物多糖、制备方法及用于制备化妆品的用途 | |
CN110452313B (zh) | 一种精制植物多糖、制备方法及在制备化妆品方面的应用 | |
CN115120659B (zh) | 一种用于中医按摩疗法的涂擦护理软膏配方及制作方法 | |
CN109999121A (zh) | 治疗弱视外用中药膏及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20211217 Address after: 201100 No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant after: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant after: Beiqingjiahua (Huangshan) Technology Co.,Ltd. Applicant after: BEIJING TECHNOLOGY AND BUSINESS University Address before: 201100 No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant before: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant before: Beiqingjiahua (Huangshan) Technology Co.,Ltd. |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20220307 Address after: 201100 No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant after: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant after: Beiqingjiahua (Huangshan) Technology Co.,Ltd. Applicant after: BEIJING TECHNOLOGY AND BUSINESS University Applicant after: YUNNAN BAIYAO GROUP HEALTH PRODUCTS Co.,Ltd. Address before: 201100 No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant before: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant before: Beiqingjiahua (Huangshan) Technology Co.,Ltd. Applicant before: BEIJING TECHNOLOGY AND BUSINESS University |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20230619 Address after: No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant after: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant after: BEIJING TECHNOLOGY AND BUSINESS University Applicant after: YUNNAN BAIYAO GROUP HEALTH PRODUCTS Co.,Ltd. Address before: 201100 No. 9, Lane 863, Jinhui Road, Minhang District, Shanghai Applicant before: Yunnan Baiyao Group Shanghai Technology Co.,Ltd. Applicant before: Beiqingjiahua (Huangshan) Technology Co.,Ltd. Applicant before: BEIJING TECHNOLOGY AND BUSINESS University Applicant before: YUNNAN BAIYAO GROUP HEALTH PRODUCTS Co.,Ltd. |
|
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211109 |