CN112220721A - 一种滋养神经末梢的护肤液配方及其应用 - Google Patents
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Abstract
本发明公开了一种滋养神经末梢的护肤液配方及其应用,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽‑1,寡肽‑2,寡肽‑5,精氨酸阿魏酸盐,1‑甲基乙内酰脲‑2‑酰亚胺,山茱萸提取物,防腐物,水。本发明安全性高,采用无添加防腐体系,无香精、色素、防腐剂,对皮肤很温和;使用效果好,有非常明显的美白亮肤效果;有良好的舒缓神经,缓解焦虑,助眠效果,具有滋养神经,舒缓神经的功效;使用体验好,通过对人群试用调查,发现对本品使用评价非常好,消费者体验效果佳。
Description
技术领域
本发明涉及护肤品技术领域,具体是一种滋养神经末梢的护肤液配方及其应用。
背景技术
随着时代的发展与人们生活水平的提高,越来越多爱美人士开始尝试医学美容。医用级护肤品也开始受到越来越多人的追捧。与普通的护肤品相比,医用级护肤品在生产上更为严格。医用级护肤品介于护肤品和药品之间,对于问题皮肤,它可以降低皮肤敏感性,作为药物的辅助治疗手段;对于健康皮肤,它可以减少刺激,维护正常的皮肤屏障和平衡,抵御外界刺激。医用级护肤品不是药品,无论皮肤有无状况,都可以使用。与普通的护肤品相比,医用级护肤品具有以下特点:(1)无菌生产:医用护肤品级采用无菌生产,包括净化生产车间及医用级原材料等等,可以直接使用于皮肤伤口,而普通的生活护肤品在各方面工艺上的要求都没有如此严格;(2)配方精简有效:原料经过严格筛选,产品安全性和有效性都经过实验和临床验证,作用机理更明确。简单概括就是:成分明确、针对性强;(3)更具有专业性;(4)功效明确,针对性强。目前市面上也存在各种功效的的医用冷敷贴,但针对神经滋养,神经营养,协助神经修复的护肤品市场上还不存在。
发明内容
本发明要解决的技术问题就是克服以上的技术缺陷,提供一种能够针对神经滋养、神经营养、协助神经修复的一种滋养神经末梢的护肤液配方及其应用。
为了解决上述问题,本发明的技术方案为:一种滋养神经末梢的护肤液配方及其应用,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽-1,寡肽-2,寡肽-5,精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物,防腐物,水。
作为改进,各原料的重量分数如下:小分子透明质酸钠0.01-0.5%,大分子透明质酸钠0.01-0.5%,超活透明质酸钠0.01-0.2%,丙烯酸共聚物0.01-0.5%,氨基酸保湿剂0.5-5%,海藻糖0.2-5%,丁二醇1-10%,维生素B12 0.0001-0.05%,寡肽-1 0.02-2%,寡肽-2 0.01-2%,寡肽-5 0.01-2%,精氨酸阿魏酸盐0.1-1%,1-甲基乙内酰脲-2-酰亚胺0.05-2%,山茱萸提取物0.2-2%,防腐物0.1-2%,余量为水。
作为改进,各原料的重量分数如下:小分子透明质酸钠0.01%,大分子透明质酸钠0.01%,超活透明质酸钠0.01%,丙烯酸共聚物0.01%,氨基酸保湿剂0.5%,海藻糖0.2%,丁二醇1%,维生素B12 0.0001%,寡肽-1 0.02%,寡肽-2 0.01%,寡肽-5 0.01%,精氨酸阿魏酸盐0.1%,1-甲基乙内酰脲-2-酰亚胺0.05%,山茱萸提取物0.2%,防腐物0.1%,余量为水。
作为改进,各原料的重量分数如下:小分子透明质酸钠0.25%,大分子透明质酸钠0.25%,超活透明质酸钠0.1%,丙烯酸共聚物0.25%,氨基酸保湿剂2.5%,海藻糖2.5%,丁二醇5%,维生素B12 0.025%,寡肽-1 1%,寡肽-2 1%,寡肽-5 1%,精氨酸阿魏酸盐0.5%,1-甲基乙内酰脲-2-酰亚胺1%,山茱萸提取物1%,防腐物1%,余量为水。
作为改进,各原料的重量分数如下:小分子透明质酸钠0.5%,大分子透明质酸钠0.5%,超活透明质酸钠0.2%,丙烯酸共聚物0.5%,氨基酸保湿剂5%,海藻糖5%,丁二醇10%,维生素B12 0.05%,寡肽-1 2%,寡肽-2 2%,寡肽-5 2%,精氨酸阿魏酸盐1%,1-甲基乙内酰脲-2-酰亚胺2%,山茱萸提取物2%,防腐物2%,余量为水。
作为改进,所述小分子透明质酸钠的分子量10-60kDa;所述大分子透明质酸钠的分子量为1000-1500kDa,超活透明质酸钠的分子量为≦5kDa。
作为改进,其制备方法包括以下步骤:
(1)将水、丁二醇、丙烯酸共聚物、大分子透明质酸钠、氨基酸保湿剂、海藻糖加入乳化设备中,搅拌加热至85℃,保温20分钟,杀菌消毒,然后在搅拌状态下开始降温;
(2)降温至45℃,加入小分子透明质酸钠、超活透明质酸钠、维生素B12、细胞能量肽、精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物、寡肽-1、寡肽-2、寡肽-5、防腐物,即得本发明滋养神经末梢的护肤液;
(3)留样以供后续检测与改进。
作为改进,所述防腐物为不列入防腐剂名录内的抗氧化剂和保湿剂。
作为改进,所述护肤液应用于面霜水乳直接涂抹、加入面膜敷用等。
本发明与现有的技术相比的优点在于:本发明安全性高,采用无添加防腐体系,无香精、色素、防腐剂,对皮肤很温和,目前对100位20-40岁的人群进行测试,无一人有过敏反应;使用效果好,通过对部分人群进行手臂测试实验,均有非常明显的美白亮肤效果。通过对部分特殊人群跟踪调查及实验测试,发现有良好的舒缓神经,缓解焦虑,助眠效果,具有滋养神经,舒缓神经的功效;使用体验好,通过对人群试用调查,发现对本品使用评价非常好,消费者体验效果佳。
具体实施方式
以下通过具体实施例进一步描述本发明,但本发明不仅仅限于以下实施例。在本发明的范围内或者在不脱离本发明的内容、精神和范围内,对本发明进行的变更、组合或替换,对于本领域的技术人员来说是显而易见的,且包含在本发明的范围之内。
实施例一
一种滋养神经末梢的护肤液配方及其应用,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽-1,寡肽-2,寡肽-5,精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物,防腐物,水。各原料的重量分数如下:小分子透明质酸钠0.01%,大分子透明质酸钠0.01%,超活透明质酸钠0.01%,丙烯酸共聚物0.01%,氨基酸保湿剂0.5%,海藻糖0.2%,丁二醇1%,维生素B12 0.0001%,寡肽-1 0.02%,寡肽-2 0.01%,寡肽-5 0.01%,精氨酸阿魏酸盐0.1%,1-甲基乙内酰脲-2-酰亚胺0.05%,山茱萸提取物0.2%,防腐物0.1%,余量为水。
按照以下步骤进行制备:(1)将水、丁二醇、丙烯酸共聚物、大分子透明质酸钠、氨基酸保湿剂、海藻糖加入乳化设备中,搅拌加热至85℃,保温20分钟,杀菌消毒,然后在搅拌状态下开始降温;
(2)降温至45℃,加入小分子透明质酸钠、超活透明质酸钠、维生素B12、细胞能量肽、精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物、寡肽-1、寡肽-2、寡肽-5、防腐物,即得本发明滋养神经末梢的护肤液;
(3)留样以供后续检测与改进。
将本护肤液加入面霜,直接涂抹于皮肤,短期内即有非常明显的美白亮肤效果,长期使用,能良好的舒缓神经,缓解焦虑,助眠等。
实施例二
一种滋养神经末梢的护肤液配方及其应用,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽-1,寡肽-2,寡肽-5,精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物,防腐物,水。各原料的重量分数如下:小分子透明质酸钠0.25%,大分子透明质酸钠0.25%,超活透明质酸钠0.1%,丙烯酸共聚物0.25%,氨基酸保湿剂2.5%,海藻糖2.5%,丁二醇5%,维生素B12 0.025%,寡肽-1 1%,寡肽-2 1%,寡肽-5 1%,精氨酸阿魏酸盐0.5%,1-甲基乙内酰脲-2-酰亚胺1%,山茱萸提取物1%,防腐物1%,余量为水。
按照以下步骤进行制备:(1)将水、丁二醇、丙烯酸共聚物、大分子透明质酸钠、氨基酸保湿剂、海藻糖加入乳化设备中,搅拌加热至85℃,保温20分钟,杀菌消毒,然后在搅拌状态下开始降温;
(2)降温至45℃,加入小分子透明质酸钠、超活透明质酸钠、维生素B12、细胞能量肽、精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物、寡肽-1、寡肽-2、寡肽-5、防腐物,即得本发明滋养神经末梢的护肤液;
(3)留样以供后续检测与改进。
将本护肤液做成水乳,短期内即有非常明显的美白亮肤效果,长期使用,能良好的舒缓神经,缓解焦虑,助眠等。
实施例三
一种滋养神经末梢的护肤液配方及其应用,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽-1,寡肽-2,寡肽-5,精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物,防腐物,水。各原料的重量分数如下:小分子透明质酸钠0.5%,大分子透明质酸钠0.5%,超活透明质酸钠0.2%,丙烯酸共聚物0.5%,氨基酸保湿剂5%,海藻糖5%,丁二醇10%,维生素B12 0.05%,寡肽-1 2%,寡肽-2 2%,寡肽-5 2%,精氨酸阿魏酸盐1%,1-甲基乙内酰脲-2-酰亚胺2%,山茱萸提取物2%,防腐物2%,余量为水。
按照以下步骤进行制备:(1)将水、丁二醇、丙烯酸共聚物、大分子透明质酸钠、氨基酸保湿剂、海藻糖加入乳化设备中,搅拌加热至85℃,保温20分钟,杀菌消毒,然后在搅拌状态下开始降温;
(2)降温至45℃,加入小分子透明质酸钠、超活透明质酸钠、维生素B12、细胞能量肽、精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物、寡肽-1、寡肽-2、寡肽-5、防腐物,即得本发明滋养神经末梢的护肤液;
(3)留样以供后续检测与改进。
将本护肤液与蚕丝布封装、灭菌,做成面膜敷用,短期内即有非常明显的美白亮肤效果,长期使用,能良好的舒缓神经,缓解焦虑,助眠等。
以上所述仅为本发明专利的较佳实施例而已,并不用以限制本发明专利,凡在本发明专利的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明专利的保护范围之内。
Claims (9)
1.一种滋养神经末梢的护肤液配方,其特征在于,由以下原料制成:小分子透明质酸钠,大分子透明质酸钠,超活透明质酸钠,丙烯酸共聚物,氨基酸保湿剂,海藻糖,丁二醇,维生素B12,寡肽-1,寡肽-2,寡肽-5,精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物,防腐物,水。
2.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于,各原料的重量分数如下:小分子透明质酸钠0.01-0.5%,大分子透明质酸钠0.01-0.5%,超活透明质酸钠0.01-0.2%,丙烯酸共聚物0.01-0.5%,氨基酸保湿剂0.5-5%,海藻糖0.2-5%,丁二醇1-10%,维生素B12 0.0001-0.05%,寡肽-1 0.02-2%,寡肽-2 0.01-2%,寡肽-5 0.01-2%,精氨酸阿魏酸盐0.1-1%,1-甲基乙内酰脲-2-酰亚胺0.05-2%,山茱萸提取物0.2-2%,防腐物0.1-2%,余量为水。
3.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于,各原料的重量分数如下:小分子透明质酸钠0.01%,大分子透明质酸钠0.01%,超活透明质酸钠0.01%,丙烯酸共聚物0.01%,氨基酸保湿剂0.5%,海藻糖0.2%,丁二醇1%,维生素B120.0001%,寡肽-1 0.02%,寡肽-2 0.01%,寡肽-5 0.01%,精氨酸阿魏酸盐0.1%,1-甲基乙内酰脲-2-酰亚胺0.05%,山茱萸提取物0.2%,防腐物0.1%,余量为水。
4.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于,各原料的重量分数如下:小分子透明质酸钠0.25%,大分子透明质酸钠0.25%,超活透明质酸钠0.1%,丙烯酸共聚物0.25%,氨基酸保湿剂2.5%,海藻糖2.5%,丁二醇5%,维生素B12 0.025%,寡肽-1 1%,寡肽-2 1%,寡肽-5 1%,精氨酸阿魏酸盐0.5%,1-甲基乙内酰脲-2-酰亚胺1%,山茱萸提取物1%,防腐物1%,余量为水。
5.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于,各原料的重量分数如下:小分子透明质酸钠0.5%,大分子透明质酸钠0.5%,超活透明质酸钠0.2%,丙烯酸共聚物0.5%,氨基酸保湿剂5%,海藻糖5%,丁二醇10%,维生素B12 0.05%,寡肽-12%,寡肽-2 2%,寡肽-5 2%,精氨酸阿魏酸盐1%,1-甲基乙内酰脲-2-酰亚胺2%,山茱萸提取物2%,防腐物2%,余量为水。
6.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于:所述小分子透明质酸钠的分子量10-60kDa;所述大分子透明质酸钠的分子量为1000-1500kDa,超活透明质酸钠的分子量为≦5kDa。
7.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于,其制备方法包括以下步骤:
(1)将水、丁二醇、丙烯酸共聚物、大分子透明质酸钠、氨基酸保湿剂、海藻糖加入乳化设备中,搅拌加热至85℃,保温20分钟,杀菌消毒,然后在搅拌状态下开始降温;
(2)降温至45℃,加入小分子透明质酸钠、超活透明质酸钠、维生素B12、细胞能量肽、精氨酸阿魏酸盐,1-甲基乙内酰脲-2-酰亚胺,山茱萸提取物、寡肽-1、寡肽-2、寡肽-5、防腐物,即得本发明滋养神经末梢的护肤液;
(3)留样以供后续检测与改进。
8.根据权利要求1所述的一种滋养神经末梢的护肤液配方,其特征在于:所述防腐物为不列入防腐剂名录内的抗氧化剂和保湿剂。
9.一种滋养神经末梢的护肤液的应用,其特征在于:所述护肤液应用于面霜水乳直接涂抹、加入面膜敷用等。
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