CN108185218A - A kind of dedicated feed addictive of grass carp protect liver - Google Patents

A kind of dedicated feed addictive of grass carp protect liver Download PDF

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Publication number
CN108185218A
CN108185218A CN201711372773.2A CN201711372773A CN108185218A CN 108185218 A CN108185218 A CN 108185218A CN 201711372773 A CN201711372773 A CN 201711372773A CN 108185218 A CN108185218 A CN 108185218A
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China
Prior art keywords
liver
grass carp
feed addictive
feed
bile acid
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Pending
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CN201711372773.2A
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Chinese (zh)
Inventor
赵帅兵
吴文俊
张定文
于菲
许彬彬
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Tian Bang Food Ltd By Share Ltd
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Tian Bang Food Ltd By Share Ltd
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Priority to CN201711372773.2A priority Critical patent/CN108185218A/en
Publication of CN108185218A publication Critical patent/CN108185218A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins

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  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)

Abstract

The invention discloses a kind of dedicated feed addictive of grass carp protect liver, the raw material weight component formula of the feed addictive is as follows:Bile acid 20 30, DL carnitines 10 15, vitamin C 20 30, astragalus polyose 20 30, curcumin 20 30;The feed addictive additive amount is small, and adding proportion is 0.1 0.2%, and common prevention dosage is 0.1%;High temperature resistant, after high temperature puffing is pelletized, the active ingredient volume of holding is still more than 95%, it is suitble to grass carp puffing material using effect interworking, it is synergistic, liver fat transhipment and oxidation energy supply are promoted with bile acid and carnitine, the anti-oxidant and immune function of liver is improved with astragalus polyose, curcumin and vitamin C, safeguards liver health;Liver body ratio is can obviously reduce, improves rate of body weight gain, feed coefficient is reduced, greatly improves culture efficiency.

Description

A kind of dedicated feed addictive of grass carp protect liver
Technical field
The present invention relates to feed addictives, and in particular to a kind of dedicated feed addictive of grass carp protect liver.
Background technology
Grass carp category Cypriniformes, Cyprinidae, Leuciscinae, grass carp category, national cultured output is up to 589.88 ten thousand tons within 2016, Rank freshwater fish culturing yield first place.But in recent years, grass carp pathogenesis of fatty liver rate significantly increases, and cultivates grass carp generally existing liver The phenomenon that dirty or interior fat heavy deposition, liver are fish maximum body of gland and most important metabolic organ, there is secretion courage Juice helps digest absorption function, the nutrient of absorption can also be synthesized glycogen, fat and protein or be converted into needed for body into Point, while also it is responsible for the important roles such as removing toxic substances, vitamin storage, immune.Liver fat abnormal deposition can seriously affect liver The normal operation of dirty function leads to the decline of the disorder of fish body metabolism, anti-oxidant anti-stress ability and immunity, easily Secondary communicable disease is broken out, when encountering Changes in weather, high temperature season or water body a problem that falling algae, easily induces big face Product is dead, in addition, liver fat abnormal deposition can also cause the shape of " pregnant ", seriously affects grass carp appearance, reduces economical Value.Its main cause is feed nutrition imbalance, and lipotropic factor is insufficient or long-term excess feeds and leads to grass carp fatty liver Protein, fat or carbohydrate content are excessively high in major reason, such as feed, egg can than or glycolipid than unbalance;In feed Lipotropic factor methionine, choline, carnitine the deficiencies of, help to safeguard the vitamin and trace element of physical health function Deficiency etc..Feed contents are excessively high.The strategy of prevention grass carp fatty liver such as Chinese Patent Application No. 201210161855.3 at present, Entitled a kind of probiotics for preventing grass carp fatty liver and preparation method thereof, with Chinese herbal medicine seaweed, lotus leaf, cassia seed, radish Son is raw material, and with strain fermentation into probiotics, but probiotics easily lose activity after puffing high temperature.China The number of applying for a patent 201010515417.3, a kind of entitled artifical compound feed of anti-grass carp fatty liver, though 1.5 portions of oriental wormwoods can promote Into the secretion of bile, contribute to digesting and assimilating for fat, inhibit hepatitis virus, repair hepar damnification, but live at present to oriental wormwood Property ingredient DNA purity be limited, so use when additive amount it is more.In consideration of it, it is small to be badly in need of a kind of additive amount at present, temperature tolerance It is good, significant effect and the protect liver tailored version additive for being suitble to grass carp puffing material high temperature granulating.
Invention content
The technical problems to be solved by the invention are to provide a kind of dedicated feed addictive of grass carp protect liver, additive tool Have that additive amount is few, temperature tolerance is good, is suitble to grass carp puffing material high temperature granulating, and having significantly reduces Grass Carp Liver body ratio, promotes liver fat Fat metabolism repairs liver inflammatory lesion, reduces the effect of grass carp pathogenesis of fatty liver rate
Technical solution is used by the present invention solves above-mentioned technical problem:A kind of dedicated feed addictive of grass carp protect liver, should The raw material weight component formula of feed addictive is as follows:Bile acid 20-30, DL- carnitine 10-15, vitamin C 20-30, Radix Astragali Polysaccharide 20-30,2 0-30 of curcumin.Bile acid, DL- carnitines, vitamin C are industrial chemicals, astragalus polyose and curcumin difference For the active constituent extracted from natural Chinese medicinal herb Radix Astragali and turmeric.
A kind of dedicated feed addictive of grass carp protect liver, raw materials of feed additives composition by weight formula are as follows:Bile acid 20th, DL- carnitines 10, vitamin C 30, astragalus polyose 20, curcumin 20.
The above-mentioned dedicated feed addictive of grass carp protect liver, the adding proportion in feed of grass carp are 0.1-0.2%, general pre- Anti- dosage is 0.1%.Bile acid can be promoted by 2 aspects of activity of chyle fat and raising lipase in component Fat digestion absorbs, and since cholesterol is the primary raw material of synthetic bile acid, addition bile acid can make internal cholesterol quality point Number is maintained at a metastable level, supplements the deficiency of liver endogenous secretion function, ensure fatty acid transport it is smooth into Row reduces deposition of the fat in liver, meanwhile, bile acid, which has, improves animal immunizing power, reduces in animal Endophytic bacteria The function of toxin absorption amount, Auxiliary Liver removing toxic substances, external source add the deficiency that can supplement endogenous bile acid.Carnitine can be in component Long chain fatty acids are transported as carrier by special transporting mechanism to enter in mitochondrial matrix, and promote Intramitochondrial fat The beta-oxidation effect of fat acid improves body to capacity usage ratio, reduces fat and deposited in liver, improve meat and build, promote life Long, reduction feed coefficient.Astragalus polyose in component is the active skull cap components extracted from Radix Astragali, is had antiviral, anti-swollen Knurl, anti-oxidant, adjusting humoral immunity of organism, the immune cell activated factor and other effects, at present, astragalus polyose is significant immune with it Enhancing and antivirus action, the characteristics such as in addition cheap, abundance, toxicity are low, have no drug resistance are widely used in clinic In medical herding and the cultivation of aquatic livestock, to improve, liver is anti-oxidant and immune function.Curcumin in component belongs to polyphenol Class compound, is mainly derived from the underground rhizome of curcuma plant, and molecular weight is small, it is considered to be most important effective active in turmeric Ingredient.It has both the multinomial biological function such as anti-oxidant, antibacterial, anti-inflammatory, can improve the vigor of liver digestive ferment, reduces liver Dirty middle neutral fats content, reduce liver body than with paddy the third glutamic-oxalacetic transaminease vigor in serum, safeguard liver health.Dimension in component Raw element C condensed phosphates, puffing retention ratio have different physiological roles, including anti-oxidant, anti-up to more than 90% in body Stress, immunological regulation, nutriment synthesis etc. and animal body growth and breeding it is closely bound up.
Compared with prior art the advantage of the invention is that a kind of dedicated feed addictive of grass carp protect liver, feed addition The raw material weight component formula of agent is as follows:Bile acid 20-30, DL- carnitine 10-15, vitamin C 20-30, astragalus polyose 20- 30th, curcumin 20-30;The feed addictive additive amount is small, adding proportion 0.1-0.2%, and common prevention dosage is for 0.1% It can;High temperature resistant, after high temperature puffing is pelletized, the active ingredient volume of holding is suitble to grass carp puffing material using effect still more than 95% Interworking, it is synergistic, liver fat transhipment and oxidation is promoted to energize with bile acid and carnitine, with astragalus polyose, curcumin and dimension Raw element C improves the anti-oxidant and immune function of liver, safeguards liver health;Safety, it is small to grass carp irritation, it has no drug resistance and medicine Object remains, and can be used for a long time;Liver body ratio is can obviously reduce, improves rate of body weight gain, feed coefficient is reduced, greatly improves culture efficiency.
Specific embodiment:
The present invention is described in further detail with reference to embodiments.
Embodiment 1
A kind of dedicated feed addictive of grass carp protect liver, the raw material weight component formula of the feed addictive are as follows:Bile acid 20 Kilogram, 10 kilograms of DL- carnitines, 30 kilograms of vitamin C, 20 kilograms of astragalus polyose, 20 kilograms of curcumin;They are sufficiently mixed Uniformly it is processed into feed addictive.
Embodiment 2
A kind of dedicated feed addictive of grass carp protect liver, the raw material weight component formula of the feed addictive are as follows:Bile acid 25 Kilogram, 12 kilograms of DL- carnitines, 0 kilogram of Catergen, 25 kilograms of astragalus polyose, 23 kilograms of curcumin;They are sufficiently mixed Uniformly it is processed into feed addictive.
Embodiment 3
A kind of dedicated feed addictive of grass carp protect liver, the raw material weight component formula of the feed addictive are as follows:Bile acid 30 Kilogram, 15 kilograms of DL- carnitines, 22 kilograms of vitamin C, 30 kilograms of astragalus polyose, 0 kilogram of bisdemethoxycurcumin;They are sufficiently mixed Uniformly it is processed into feed addictive.
Experimental example
Breed variety:The young grass carps 3000 of 20g or so are randomly divided into five groups:Net cage 1, net cage 2, net cage 3, net cage 4 and net Case 5, each group gross weight is suitable, every group of 5 repetitions, and 600, grass carp is always put in a suitable place to breed per networking case;Cultivating condition:Environmental factor, chemistry because Element and the net cage in the essentially identical same waters of biological factor, feeds utilized to pelletize to be puffing, formula is consistent, protein 28 %, Fat 6%;Aquaculture management:Other conditions are essentially identical, except that net cage 1 is fed daily is added with 0.1% in the feed for being (Weight)The grass carp protect liver tailored version feed addictive of embodiment 1;0.2% is added in the feed that net cage 2 is fed daily(Weight) The grass carp protect liver tailored version feed addictive of embodiment 1;0.1% is added in the feed that net cage 3 is fed daily(Weight)Embodiment 2 grass carp protect liver tailored version feed addictive;0.2% is added in the feed that net cage 4 is fed daily(Weight)The grass of embodiment 3 Fish protect liver tailored version feed addictive;Net cage 5(Control group)Grass carp protect liver tailored version feed is not added in the feed fed daily Additive;Results contrast:Culture experiment continues 2 months, calculates the specific growth rate of grass carp, feed coefficient, coefficient of condition, dirty body ratio And liver situation is observed, experimental result is as shown in table 1:
Table 1:The growth performance of each net cage grass carp and body index
Processing Whole opisthosoma weight Feed coefficient Coefficient of condition Liver body ratio Liver situation
Net cage 1 183.56 1.33 2.20 1.93 Scarlet, a small amount of fat deposition
Net cage 2 197.63 1.30 2.15 1.87 Scarlet, micro fat deposition
Net cage 3 175.82 1.35 2.23 1.97 Scarlet, a small amount of fat deposition
Net cage 4 189.90 1.31 2.17 1.88 Scarlet, micro fat deposition
Net cage 5 150.66 1.38 2.33 2.30 The colour of loess, significant quantities of fat deposition
As it can be seen from table 1 the opisthosoma more whole than net cage 5 of net cage 1,2,3,4 increases more than 16% again, feed coefficient reduces by more than 2%, fertilizer Full scale reduces by more than 4%, and for liver body than declining more than 14%, liver color is normal, illustrates the grass carp protect liver tailored version feed of the present invention Additive, having reduces Grass Carp Liver body ratio, promotes adipose metabolism, reduces the effect of grass carp pathogenesis of fatty liver rate, carries simultaneously Seedling height speed reduces feed coefficient, improves the economic benefit of grass carp cultivation, feed coefficient=total solids food ration/(end Weight-initial weight), coefficient of condition (%)=100 × end weight/body is long3, liver body ratio (%)=100 × liver weight/weight.

Claims (2)

1. a kind of dedicated feed addictive of grass carp protect liver, it is characterised in that the raw material weight component formula of the feed addictive is such as Under:Bile acid 20-30, DL- carnitine 10-15, vitamin C 20-30, astragalus polyose 20-30, curcumin 20-30.
2. a kind of dedicated feed addictive of grass carp protect liver as described in claim 1, it is characterised in that the feed addictive Raw material weight component formula is as follows:Bile acid 20, DL- carnitines 10, vitamin C 30, astragalus polyose 20, curcumin 20.
CN201711372773.2A 2017-12-19 2017-12-19 A kind of dedicated feed addictive of grass carp protect liver Pending CN108185218A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109090376A (en) * 2018-08-24 2018-12-28 天邦食品股份有限公司 A kind of functional feed for imitating wild cultivation suitable for Larimichthys crocea
CN109170365A (en) * 2018-09-14 2019-01-11 广东渔夫宝水产科技有限公司 A kind of functional feedstuff additive and its application method of cultured fishes liver protecting
CN109527273A (en) * 2019-01-15 2019-03-29 无锡华诺威动物保健品有限公司 A kind of feed addictive and preparation method for protecting special aquatic products fish liver health
CN113209062A (en) * 2021-03-24 2021-08-06 山东省淡水渔业研究院(山东省淡水渔业监测中心) Study on carp liver injury protection effect of curcumin through activation of activity of Nrf2

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Publication number Priority date Publication date Assignee Title
CN101991026A (en) * 2010-11-24 2011-03-30 广州海因特生物技术有限公司 Complex immunity reinforcing agent for improving stress resistance of black carp and preparation method thereof
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CN101991026A (en) * 2010-11-24 2011-03-30 广州海因特生物技术有限公司 Complex immunity reinforcing agent for improving stress resistance of black carp and preparation method thereof
CN102283332A (en) * 2011-08-25 2011-12-21 北京大北农科技集团股份有限公司 Feed additive and premix compound for promoting grass carp liver and immunologic function repair
CN104095143A (en) * 2013-04-15 2014-10-15 徐州市国威饲料有限公司 Preparation method of feed capable of reducing death rate of grass carp
CN106360115A (en) * 2016-08-26 2017-02-01 佛山市南海东方澳龙制药有限公司 Feed additive for preventing and treating liver diseases and preparation method of same

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109090376A (en) * 2018-08-24 2018-12-28 天邦食品股份有限公司 A kind of functional feed for imitating wild cultivation suitable for Larimichthys crocea
CN109170365A (en) * 2018-09-14 2019-01-11 广东渔夫宝水产科技有限公司 A kind of functional feedstuff additive and its application method of cultured fishes liver protecting
CN109527273A (en) * 2019-01-15 2019-03-29 无锡华诺威动物保健品有限公司 A kind of feed addictive and preparation method for protecting special aquatic products fish liver health
CN113209062A (en) * 2021-03-24 2021-08-06 山东省淡水渔业研究院(山东省淡水渔业监测中心) Study on carp liver injury protection effect of curcumin through activation of activity of Nrf2

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Application publication date: 20180622

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