CN107460083A - It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof - Google Patents

It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof Download PDF

Info

Publication number
CN107460083A
CN107460083A CN201710909655.4A CN201710909655A CN107460083A CN 107460083 A CN107460083 A CN 107460083A CN 201710909655 A CN201710909655 A CN 201710909655A CN 107460083 A CN107460083 A CN 107460083A
Authority
CN
China
Prior art keywords
parts
reducing blood
blood lipid
aid
care wine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710909655.4A
Other languages
Chinese (zh)
Inventor
史月龙
曾宋君
吴英亮
刘文斌
吴坤林
汤静
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Xiancaotang Biological Technology Co Ltd
Original Assignee
Nanjing Xiancaotang Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Xiancaotang Biological Technology Co Ltd filed Critical Nanjing Xiancaotang Biological Technology Co Ltd
Priority to CN201710909655.4A priority Critical patent/CN107460083A/en
Publication of CN107460083A publication Critical patent/CN107460083A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/02Preparation of other alcoholic beverages by fermentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/22Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof, by weight, 32~65 parts of Scorpio extract, 22~45 parts of Radix Angelicae Sinensis, 20~40 parts of leech, 15~35 parts of spina date seed, 12~30 parts of matrimony vine, 8~19 parts of corydalis tuber, 9~21 parts of Chinese yam, 8~22 parts of the bark of eucommia, 7~19 parts of mountain jujube, 6~20 parts of ginkgo leaf, 5~18 parts of grape pip, 23~48 parts of wheat, 20~55 parts of glutinous rice, 40~80 parts of mineral water.It is produced by the present invention be used to aiding in reducing blood lipid scorpion health-care wine have the function that wind-expelling pain-stopping, it is clearing heat and detoxicating, remove obstruction in channels to relieve pain, blood-activating and qi-promoting dissipates the stasis of blood, promotes the production of body fluid and middle emergency, wind-damp dispelling numbness pain.

Description

It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
Technical field
The present invention relates to a kind of health food, more particularly to a kind of scorpion health-care wine and its preparation for being used to aid in reducing blood lipid Method, belong to food processing technology field.
Background technology
Due to the raising of quality of life, hyperglycaemia, high fat of blood, hypertension, which are increasingly becoming, threatens the three of human health to kill greatly Hand, and the trend of rejuvenation is presented, have a strong impact on the quality of life of people.And most of hyperlipemic patients have simultaneously Hypertension symptom, easily cause the generation of apoplexy, angiocardiopathy, if can not prevent and treat early, consequence is very serious.
Hyperlipemia can be divided into primary and the class of Secondary cases two.Primary is relevant with congenital and heredity, is due to single base Because of defect or polygenes defect, acceptor, enzyme or the apolipoprotein caused by abnormal for participation lipoprotein is transported and is metabolized, or due to ring Border factor (diet, nutrition, medicine) and caused by unknown mechanism.Secondary cases is occurred in metabolic disorder disease (glycosuria Disease, hypertension, myxedema, hypothyroidism, obesity, liver and kidney disease, adrenal cortex function are hyperfunction), or and its His factor for example the age, sex, season, drink, smoking, diet, physical exertion, stress, emotional activity etc. it is relevant.
Clinically the medicine of conventional reducing blood lipid has Statins, is inhibitor of cholesterol biosynthetic enzyme, for clinic at present Most widely used a kind of lipid-regulation medicine, it is the key agents of current treatment hypercholesterolemia, it is anti-that such medicine has stomach and intestine It, should have a headache, musclar toxicity be likely to occur when being shared with other fat-reducing medicaments;Fibrates, be mainly used in hypertriglyceridemia or Mixed type high fat of blood mass formed by blood stasis based on triglycerides rise, the common adverse reaction of the medicine is gastrointestinal reaction, nausea, diarrhoea, tight Severe one can cause hepatic lesion.Therefore, it was noticed that although these medicines have the effect of certain, but side effect is larger, for body For the weaker crowd of voxel matter, be not suitable for using.Compared with Western medicine preparation, Chinese medicine preparation has the spy of Mutiple Targets, manifold effect Point, but Chinese medicine in the market is treated some and cured the symptoms, not the disease, and some use expensive composition, many product drops DeGrain is pressed, effect is unstable after decompression, it is easy to which bounce-back rises.
The content of the invention
The purpose of the present invention is:The defects of in order to overcome prior art, reducing blood lipid can be aided in by obtaining one kind, be given full play to The drug effect of Chinese medicine, or the effect stability of other blood lipid-lowering medicines, it is used to aid in reducing blood lipid complete the invention provides one kind Scorpion health liquor and preparation method thereof.
In order to achieve the above objects and other related objects, technical scheme provided by the invention is:One kind is used to aid in drop blood The scorpion health-care wine of fat, the component for being used to aid in the composition of raw materials of the scorpion health-care wine of reducing blood lipid to include following parts by weight:
Preferably technical scheme is:It is described to be used to aid in the composition of raw materials of the scorpion health-care wine of reducing blood lipid to include following weight The component of part:
In order to achieve the above objects and other related objects, technical scheme provided by the invention is:One kind is used to aid in drop blood The preparation method of the scorpion health-care wine of fat, it is described to be used to aid in the composition of raw materials of the scorpion health-care wine of reducing blood lipid to include following weight The component of part:
Preparation method includes preparation technology, the preparation technology of Scorpio extract and the zymotechnique of fermentation raw material;The hair The preparation technology of ferment raw material comprises the following steps:
The first step:Wheat, glutinous rice are soaked in water, water temperature is controlled at 30~40 DEG C, is soaked 8~15 hours;
Second step:By the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, Du Secondary, mountain jujube, ginkgo leaf, grape pip crush, and tile after mixing, are steamed 30~60 minutes under the conditions of 105~120 DEG C;
3rd step:The product obtained with the hot-water soak second step that temperature is 65~85 DEG C, soaks 30~55 minutes, gauze Filtering, the trapped substance on gauze is collected, is dried under the conditions of being placed in 58~70 DEG C, obtain fermentation raw material;
The preparation technology of the Scorpio extract includes:Under the conditions of 4~8 DEG C, scorpio is subjected to fiber crops with ethanol or ether Liquor-saturated processing, then freezed 1~5 hour under the conditions of -16~-30 DEG C;The volume integral of 1~3.5 times of quality is added after grinding Number is 75~90% ethanol, is ground into slurries, and 3000~5000r/min centrifuges 5~10min, takes supernatant;To the supernatant Ethanol is added in liquid, 12000~14000r/min centrifuges 15~25min after shaking up, and collects precipitation and obtains Scorpio extract;
The zymotechnique comprises the following steps:
The first step:The fermentation raw material and Scorpio extract mixing are added in one pottery Zhen, by temperature in the pottery Zhen Degree is adjusted to 25~30 DEG C, accesses bacillus coagulans and monascus, and the access amount of bacillus coagulans and monascus is 20~ 24mL/kg, fermented 10~22 days under the conditions of 25~30 DEG C, obtain zymotic fluid;
Second step:The zymotic fluid is imported in ground pot, steam is opened and is distilled, connect wine final concentration of 55%~70% (V/V) scorpion health-care wine for aiding in reducing blood lipid, that is, is obtained.
Preferably technical scheme is:It is described to be used to aid in the composition of raw materials of the scorpion health-care wine of reducing blood lipid to include following weight The component of part:
Preferably technical scheme is:Preparation method includes preparation technology, the preparation technology of Scorpio extract of fermentation raw material And zymotechnique;The preparation technology of the fermentation raw material comprises the following steps:
The first step:Wheat, glutinous rice are soaked in water, water temperature is controlled at 36 DEG C, is soaked 12 hours;
Second step:By the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, Du Secondary, mountain jujube, ginkgo leaf, grape pip crush, and tile after mixing, are steamed 50 minutes under the conditions of 112 DEG C;
3rd step:The product obtained with the hot-water soak second step that temperature is 80 DEG C, soaks 50 minutes, filtered through gauze, receives Collect the trapped substance on gauze, dried under the conditions of being placed in 65 DEG C, obtain fermentation raw material;
The preparation technology of the Scorpio extract includes:Under the conditions of 6 DEG C, scorpio is carried out at anesthesia with ethanol or ether Reason, is then freezed 4 hours under the conditions of -20 DEG C;The volume fraction that 2.5 times of quality are added after grinding is 85% ethanol, Slurries are ground into, 4000r/min centrifugation 8min, take supernatant;Ethanol is added into the supernatant, shakes up rear 13000r/min 20min is centrifuged, precipitation is collected and obtains Scorpio extract;
The zymotechnique comprises the following steps:
The first step:The fermentation raw material and Scorpio extract mixing are added in one pottery Zhen, by temperature in the pottery Zhen Degree is adjusted to 28 DEG C, accesses bacillus coagulans and monascus, and the access amount of bacillus coagulans and monascus is 22mL/kg, Fermented 18 days under the conditions of 28 DEG C, obtain zymotic fluid;
Second step:The zymotic fluid is imported in ground pot, steam is opened and is distilled, connect wine final concentration of 65% (V/V), Obtain the scorpion health-care wine for aiding in reducing blood lipid.
Because above-mentioned technical proposal is used, the present invention this have the advantage that compared with prior art:
1st, it is produced by the present invention be used for aid in reducing blood lipid scorpion health-care wine have wind-expelling pain-stopping, it is clearing heat and detoxicating, remove obstruction in channels to relieve pain, Blood-activating and qi-promoting dissipates the stasis of blood, promotes the production of body fluid and middle emergency, the effect of wind-damp dispelling numbness pain.
2nd, it is produced by the present invention to be used to aid in the drug effect that reducing blood lipid scorpion health-care wine gives full play to Chinese medicine, or other drops The effect stability of hypolipidemic medicine.
Embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this implementation Content disclosed by example understands other advantages and effect of the present invention easily.
Embodiment 1:It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
A kind of scorpion health-care wine for being used to aid in reducing blood lipid, it is by weight, described to be used to aid in the scorpio of reducing blood lipid to protect The composition of raw materials of strong wine includes:32 parts of Scorpio extract, 22 parts of Radix Angelicae Sinensis, 20 parts of leech, 15 parts of spina date seed, 12 parts of matrimony vine, prolong recklessly 8 parts of rope, 9 parts of Chinese yam, 8 parts of the bark of eucommia, 7 parts of mountain jujube, 6 parts of ginkgo leaf, 5 parts of grape pip, 23 parts of wheat, 20 parts of glutinous rice, mineral water 40 Part.
Preparation method comprises the following steps:
(1) wheat, glutinous rice are soaked in mineral water, water temperature is controlled at 30 DEG C, is soaked 8 hours.
(2) by the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, the bark of eucommia, mountain Jujube, ginkgo leaf, grape pip crush, and then mix, tile, are steamed 30 minutes under the conditions of 105 DEG C.
(3) with the product for the hot-water soak step (2) that temperature is 65 DEG C, soak 30 minutes, filtered through gauze removes soaked, receipts Collect the trapped substance on gauze, dried under the conditions of being placed in 58 DEG C, obtain fermentation raw material.
(4) by scorpio under the conditions of 4 DEG C, anaesthetic treatment is carried out with ethanol, is then freezed 1 hour under the conditions of -16 DEG C;Grind The ethanol that the broken rear volume fraction for adding 1 times of quality that is milled is 75%, is ground into slurries, 3000r/min centrifugation 5min, takes supernatant Liquid;The volume fraction that 1 times of quality is added into supernatant is 75% ethanol, shakes up rear 12000r/min centrifugations 15min, collects Precipitation, the precipitation is Scorpio extract.Anaesthetic treatment refers to scorpio adult being immersed in ethanol or ether, or to scorpio Adult carries out ethanol or ether spray.
(5) precipitation that the fermentation raw material and step (4) obtained step (3) is collected mixes, and adds Tao Zhenzhong, will make pottery in discriminating Temperature is adjusted to 25 DEG C, accesses bacillus coagulans and monascus, the access amount of each strain is 20mL/kg, under the conditions of 25 DEG C Fermentation 10 days.
(6) zymotic fluid for obtaining step (5) is imported in ground pot, is opened steam, distillation, is met the final concentration of 55% (V/ of wine V), that is, the scorpion health-care wine for aiding in reducing blood lipid is obtained.
Embodiment 2:It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
A kind of scorpion health-care wine for being used to aid in reducing blood lipid, it is by weight, described to be used to aid in the scorpio of reducing blood lipid to protect The composition of raw materials of strong wine includes:55 parts of Scorpio extract, 40 parts of Radix Angelicae Sinensis, 32 parts of leech, 30 parts of spina date seed, 26 parts of matrimony vine, prolong recklessly 14 parts of rope, 18 parts of Chinese yam, 17 parts of the bark of eucommia, 14 parts of mountain jujube, 15 parts of ginkgo leaf, 13 parts of grape pip, 43 parts of wheat, 48 parts of glutinous rice, ore deposit 70 parts of spring.
Preparation method comprises the following steps:
1) wheat, glutinous rice are soaked in mineral water, water temperature is controlled at 36 DEG C, is soaked 12 hours.
(2) by the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, the bark of eucommia, mountain Jujube, ginkgo leaf, grape pip crush, and then mix, tile, are steamed 50 minutes under the conditions of 112 DEG C.
(3) with the product for the hot-water soak step (2) that temperature is 80 DEG C, soak 50 minutes, filtered through gauze removes soaked, receipts Collect the trapped substance on gauze, dried under the conditions of being placed in 65 DEG C, obtain fermentation raw material.
(4) by scorpio under the conditions of 6 DEG C, anaesthetic treatment is carried out with ether, is then freezed 4 hours under the conditions of -20 DEG C;Grind The ethanol that the broken rear volume fraction for adding 2.5 times of quality that is milled is 85%, is ground into slurries, 4000r/min centrifugation 8min, takes Clear liquid;The volume fraction that 0.5 times of quality is added into supernatant is 85% ethanol, shakes up rear 13000r/min centrifugations 20min, Precipitation is collected, the precipitation is Scorpio extract.Anaesthetic treatment refers to scorpio adult being immersed in ethanol or ether, or right Scorpio adult carries out ethanol or ether spray.
(5) precipitation that the fermentation raw material and step (4) obtained step (3) is collected mixes, and adds Tao Zhenzhong, will make pottery in discriminating Temperature is adjusted to 28 DEG C, accesses bacillus coagulans and monascus, the access amount of each strain is 22mL/kg, under the conditions of 28 DEG C Fermentation 18 days.
(6) zymotic fluid for obtaining step (5) is imported in ground pot, is opened steam, distillation, is met the final concentration of 65% (V/ of wine V), that is, the scorpion health-care wine for aiding in reducing blood lipid is obtained.
Embodiment 3:It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
A kind of scorpion health-care wine for being used to aid in reducing blood lipid, it is by weight, described to be used to aid in the scorpio of reducing blood lipid to protect The composition of raw materials of strong wine includes:65 parts of Scorpio extract, 45 parts of Radix Angelicae Sinensis, 40 parts of leech, 35 parts of spina date seed, 30 parts of matrimony vine, prolong recklessly 19 parts of rope, 21 parts of Chinese yam, 22 parts of the bark of eucommia, 19 parts of mountain jujube, 20 parts of ginkgo leaf, 18 parts of grape pip, 48 parts of wheat, 55 parts of glutinous rice, ore deposit 80 parts of spring.
Preparation method comprises the following steps:
(1) wheat, glutinous rice are soaked in mineral water, water temperature is controlled at 40 DEG C, is soaked 15 hours.
(2) by the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, the bark of eucommia, mountain Jujube, ginkgo leaf, grape pip crush, and then mix, tile, are steamed 60 minutes under the conditions of 120 DEG C.
(3) with the product for the hot-water soak step (2) that temperature is 85 DEG C, soak 55 minutes, filtered through gauze removes soaked, receipts Collect the trapped substance on gauze, dried under the conditions of being placed in 70 DEG C, obtain fermentation raw material.
(4) by scorpio under the conditions of 8 DEG C, anaesthetic treatment is carried out with ethanol, is then freezed 5 hours under the conditions of -30 DEG C;Grind The ethanol that the broken rear volume fraction for adding 3.5 times of quality that is milled is 90%, is ground into slurries, 5000r/min centrifugation 10min, takes Supernatant;The volume fraction that 0.2 times of quality is added into supernatant is 90% ethanol, shakes up rear 14000r/min centrifugations 25min, precipitation is collected, the precipitation is Scorpio extract.Anaesthetic treatment refers to scorpio adult being immersed in ethanol or ether, Or ethanol or ether spray are carried out to scorpio adult.
(5) precipitation that the fermentation raw material and step (4) obtained step (3) is collected mixes, and adds Tao Zhenzhong, will make pottery in discriminating Temperature is adjusted to 30 DEG C, accesses bacillus coagulans and monascus, the access amount of each strain is 24mL/kg, under the conditions of 30 DEG C Fermentation 22 days.
(6) zymotic fluid for obtaining step (5) is imported in ground pot, is opened steam, distillation, is met the final concentration of 70% (V/ of wine V), that is, the scorpion health-care wine for aiding in reducing blood lipid is obtained.
What the embodiment of the present invention 1~3 was prepared is used to aid in the progress performance test of reducing blood lipid scorpion health-care wine, as a result It is as shown in the table:
Embodiment 1 Embodiment 2 Embodiment 3
Vinegar drone 39.8 51.2 47.8
Ethyl palmitate 28.9 21.3 24.8
Ethyl oleate 9.3 6.2 7.8
Ethyl linoleate 15.8 10.9 11.9
Embodiment 4:It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
A kind of preparation method for being used to aid in the scorpion health-care wine of reducing blood lipid, the scorpion health-care for being used to aid in reducing blood lipid The composition of raw materials of wine includes the component of following parts by weight:
Preparation method includes preparation technology, the preparation technology of Scorpio extract and the zymotechnique of fermentation raw material;The hair The preparation technology of ferment raw material comprises the following steps:
The first step:Wheat, glutinous rice are soaked in water, water temperature is controlled at 40 DEG C, is soaked 8 hours;
Second step:By the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, Du Secondary, mountain jujube, ginkgo leaf, grape pip crush, and tile after mixing, are steamed 45 minutes under the conditions of 115 DEG C;
3rd step:The product obtained with the hot-water soak second step that temperature is 75 DEG C, soaks 50 minutes, filtered through gauze, receives Collect the trapped substance on gauze, dried under the conditions of being placed in 60 DEG C, obtain fermentation raw material;
The preparation technology of the Scorpio extract includes:Under the conditions of 7 DEG C, scorpio is carried out at anesthesia with ethanol or ether Reason, is then freezed 3.5 hours under the conditions of -19 DEG C;The volume fraction that 2.5 times of quality are added after grinding is 80% second Alcohol, slurries are ground into, 4500r/min centrifugation 10min, take supernatant;Ethanol is added into the supernatant, after shaking up 12000r/min centrifuges 25min, collects precipitation and obtains Scorpio extract;
The zymotechnique comprises the following steps:
The first step:The fermentation raw material and Scorpio extract mixing are added in one pottery Zhen, by temperature in the pottery Zhen Degree is adjusted to 28 DEG C, accesses bacillus coagulans and monascus, and the access amount of bacillus coagulans and monascus is 20mL/kg, Fermented 19 days under the conditions of 26 DEG C, obtain zymotic fluid;
Second step:The zymotic fluid is imported in ground pot, steam is opened and is distilled, connect wine final concentration of 58% (V/V) (volume/volume), that is, obtain the scorpion health-care wine for aiding in reducing blood lipid.
As described above is only to explain the preferred embodiments of the invention, is not intended to tool to do any shape to the present invention Limitation in formula, therefore all have any modification or change for making the relevant present invention under identical spirit, it should all wrap Include the invention is intended to the category protected.

Claims (5)

  1. A kind of 1. scorpion health-care wine for being used to aid in reducing blood lipid, it is characterised in that:The scorpion health-care for being used to aid in reducing blood lipid The composition of raw materials of wine includes the component of following parts by weight:
    32~65 parts of Scorpio extract;
    22~45 parts of Radix Angelicae Sinensis;
    20~40 parts of leech;
    15~35 parts of spina date seed;
    12~30 parts of matrimony vine;
    8~19 parts of corydalis tuber;
    9~21 parts of Chinese yam;
    8~22 parts of the bark of eucommia;
    7~19 parts of mountain jujube;
    6~20 parts of ginkgo leaf;
    5~18 parts of grape pip;
    23~48 parts of wheat;
    20~55 parts of glutinous rice;
    40~80 parts of water.
  2. 2. the scorpion health-care wine according to claim 1 for being used to aid in reducing blood lipid, it is characterised in that:It is described to be used to aid in drop The composition of raw materials of the scorpion health-care wine of blood fat includes the component of following parts by weight:
    55 parts of Scorpio extract;
    40 parts of Radix Angelicae Sinensis;
    32 parts of leech;
    30 parts of spina date seed;
    26 parts of matrimony vine;
    14 parts of corydalis tuber;
    18 parts of Chinese yam;
    17 parts of the bark of eucommia;
    14 parts of mountain jujube;
    15 parts of ginkgo leaf;
    13 parts of grape pip;
    43 parts of wheat;
    48 parts of glutinous rice;
    70 parts of water.
  3. A kind of 3. preparation method for being used to aid in the scorpion health-care wine of reducing blood lipid, it is characterised in that:It is described to be used to aid in reducing blood lipid The composition of raw materials of scorpion health-care wine include the components of following parts by weight:
    32~65 parts of Scorpio extract;
    22~45 parts of Radix Angelicae Sinensis;
    20~40 parts of leech;
    15~35 parts of spina date seed;
    12~30 parts of matrimony vine;
    8~19 parts of corydalis tuber;
    9~21 parts of Chinese yam;
    8~22 parts of the bark of eucommia;
    7~19 parts of mountain jujube;
    6~20 parts of ginkgo leaf;
    5~18 parts of grape pip;
    23~48 parts of wheat;
    20~55 parts of glutinous rice:
    40~80 parts of water;
    Preparation method includes preparation technology, the preparation technology of Scorpio extract and the zymotechnique of fermentation raw material;The proferment The preparation technology of material comprises the following steps:
    The first step:Wheat, glutinous rice are soaked in water, water temperature is controlled at 30~40 DEG C, is soaked 8~15 hours;
    Second step:By the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, the bark of eucommia, mountain Jujube, ginkgo leaf, grape pip crush, and tile after mixing, are steamed 30~60 minutes under the conditions of 105~120 DEG C;
    3rd step:The product obtained with the hot-water soak second step that temperature is 65~85 DEG C, soaks 30~55 minutes, gauze mistake Filter, the trapped substance on gauze is collected, is dried under the conditions of being placed in 58~70 DEG C, obtain fermentation raw material;
    The preparation technology of the Scorpio extract includes:Under the conditions of 4~8 DEG C, scorpio is carried out at anesthesia with ethanol or ether Reason, is then freezed 1~5 hour under the conditions of -16~-30 DEG C;The volume fraction of 1~3.5 times of quality of addition is after grinding 75~90% ethanol, is ground into slurries, and 3000~5000r/min centrifuges 5~10min, takes supernatant;Into the supernatant Ethanol is added, 12000~14000r/min centrifuges 15~25min after shaking up, and collects precipitation and obtains Scorpio extract;
    The zymotechnique comprises the following steps:
    The first step:The fermentation raw material and Scorpio extract mixing are added in one pottery Zhen, temperature in the pottery Zhen is adjusted To 25~30 DEG C, bacillus coagulans and monascus are accessed, the access amount of bacillus coagulans and monascus is 20~24mL/ Kg, fermented 10~22 days under the conditions of 25~30 DEG C, obtain zymotic fluid;
    Second step:The zymotic fluid is imported in ground pot, steam is opened and is distilled, connect wine final concentration of 55%~70%(V/V), Obtain the scorpion health-care wine for aiding in reducing blood lipid.
  4. 4. the preparation method according to claim 3 for being used to aid in the scorpion health-care wine of reducing blood lipid, it is characterised in that:It is described The composition of raw materials of scorpion health-care wine for aiding in reducing blood lipid includes the component of following parts by weight:
    55 parts of Scorpio extract;
    40 parts of Radix Angelicae Sinensis;
    32 parts of leech;
    30 parts of spina date seed;
    26 parts of matrimony vine;
    14 parts of corydalis tuber;
    18 parts of Chinese yam;
    17 parts of the bark of eucommia;
    14 parts of mountain jujube;
    15 parts of ginkgo leaf;
    13 parts of grape pip;
    43 parts of wheat;
    48 parts of glutinous rice;
    70 parts of water.
  5. 5. the preparation method according to claim 3 for being used to aid in the scorpion health-care wine of reducing blood lipid, it is characterised in that:Prepare Method includes preparation technology, the preparation technology of Scorpio extract and the zymotechnique of fermentation raw material;The preparation of the fermentation raw material Technique comprises the following steps:
    The first step:Wheat, glutinous rice are soaked in water, water temperature is controlled at 36 DEG C, is soaked 12 hours;
    Second step:By the wheat and glutinous rice after immersion, and Radix Angelicae Sinensis, leech, spina date seed, matrimony vine, corydalis tuber, Chinese yam, the bark of eucommia, mountain Jujube, ginkgo leaf, grape pip crush, and tile after mixing, are steamed 50 minutes under the conditions of 112 DEG C;
    3rd step:The product obtained with the hot-water soak second step that temperature is 80 DEG C, soaks 50 minutes, filtered through gauze, collects yarn Trapped substance on cloth, dried under the conditions of being placed in 65 DEG C, obtain fermentation raw material;
    The preparation technology of the Scorpio extract includes:Under the conditions of 6 DEG C, scorpio is subjected to anaesthetic treatment with ethanol or ether, Then freezed 4 hours under the conditions of -20 DEG C;The volume fraction that 2.5 times of quality are added after grinding is 85% ethanol, is ground Into slurries, 4000r/min centrifugation 8min, supernatant is taken;Ethanol is added into the supernatant, shakes up rear 13000r/min centrifugations 20min, collect precipitation and obtain Scorpio extract;
    The zymotechnique comprises the following steps:
    The first step:The fermentation raw material and Scorpio extract mixing are added in one pottery Zhen, temperature in the pottery Zhen is adjusted To 28 DEG C, bacillus coagulans and monascus are accessed, the access amount of bacillus coagulans and monascus is 22mL/kg, 28 Fermented 18 days under the conditions of DEG C, obtain zymotic fluid;
    Second step:The zymotic fluid is imported in ground pot, steam is opened and is distilled, connect wine final concentration of 65%(V/V), that is, obtain The scorpion health-care wine for aiding in reducing blood lipid must be used for.
CN201710909655.4A 2017-09-29 2017-09-29 It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof Pending CN107460083A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710909655.4A CN107460083A (en) 2017-09-29 2017-09-29 It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710909655.4A CN107460083A (en) 2017-09-29 2017-09-29 It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107460083A true CN107460083A (en) 2017-12-12

Family

ID=60553831

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710909655.4A Pending CN107460083A (en) 2017-09-29 2017-09-29 It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107460083A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107629910A (en) * 2017-10-09 2018-01-26 南京图艾生物医药科技有限公司 One kind is used to aid in reducing blood lipid scorpion health-care wine and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1159929A (en) * 1996-03-18 1997-09-24 江西赣东钳蝎研究所 Process for producing health Buthus martensi liquor
CN106399002A (en) * 2016-12-18 2017-02-15 周世容 Baijiu brewing technology
CN106539893A (en) * 2016-09-21 2017-03-29 深圳市得道中医馆管理有限责任公司 A kind of application of Chinese medicine composition and preparation method thereof and treatment cerebrovascular sclerosiss
CN106754130A (en) * 2016-12-24 2017-05-31 李珊珊 Health liquor and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1159929A (en) * 1996-03-18 1997-09-24 江西赣东钳蝎研究所 Process for producing health Buthus martensi liquor
CN106539893A (en) * 2016-09-21 2017-03-29 深圳市得道中医馆管理有限责任公司 A kind of application of Chinese medicine composition and preparation method thereof and treatment cerebrovascular sclerosiss
CN106399002A (en) * 2016-12-18 2017-02-15 周世容 Baijiu brewing technology
CN106754130A (en) * 2016-12-24 2017-05-31 李珊珊 Health liquor and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
谭银合等: ""全蝎蝎毒蛋白的提取工艺研究"", 《湖南中医药导报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107629910A (en) * 2017-10-09 2018-01-26 南京图艾生物医药科技有限公司 One kind is used to aid in reducing blood lipid scorpion health-care wine and preparation method thereof

Similar Documents

Publication Publication Date Title
GB2589967A (en) Chinese yellow rice wine containing ingredients of mulberry leaves (morus alba L.) and silkworm pupae (bombyx mori) and production method thereof
CN107460083A (en) It is a kind of to be used to aid in scorpion health-care wine of reducing blood lipid and preparation method thereof
Peng et al. Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet
CN106867824A (en) Male silkworm essence wine and preparation method thereof
CN102205013A (en) Method for processing giant typhonium rhizome
CN104840871B (en) A kind of Chinese medicine for treating alcoholic liver damage
CN115300585B (en) Weilong bone-strengthening wine for treating rheumatic bone diseases and preparation method thereof
CN116375902A (en) Grape residue polysaccharide for improving immune function and preparation method and application thereof
CN107629910A (en) One kind is used to aid in reducing blood lipid scorpion health-care wine and preparation method thereof
CN109294797A (en) A kind of bitter buckwheat wine and preparation method thereof
CN105079532A (en) Healthcare green tea capable of reducing blood fat and loosing weight and preparation method of healthcare green tea
Vamsikrishna et al. Antidiabetic efficacy of ethanolic extract of Phragmites vallatoria on STZ induced diabetic rats
CN104906190A (en) Antler powder wine and preparation method thereof
CN110664876B (en) Extraction method of polyphenol component in Chinese date fruit drop
CN103919842B (en) Processing process of falcate dolichos root leaf medicinal material
CN102205014A (en) Method for processing rhizoma arisaematis
CN103205342B (en) Rice wine with geckos and Taibai-tea and preparation method thereof
CN105925446A (en) Twelve stamen melastoma herb root and korshinsk peashrub root liquor and making method thereof
CN107412393B (en) Preparation method and application of clausena lansium leaf polyphenol extract
CN110893203A (en) Double-order nux vomica processed product extract and preparation method thereof
US20180078595A1 (en) Inhibition of formation of amyloid b-protein fibrils using cactus mucilage extracts
CN113713016B (en) Application of seville orange flower in preparation of medicine for improving fatty liver
CN115054623B (en) Process for producing fermented soya beans
CN108606973A (en) The weight-reducing purposes of beans taro leaf polyose
CN110327392B (en) Quince-basil total flavone composition and application thereof in atherosclerosis

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20171212

RJ01 Rejection of invention patent application after publication