CN107198767A - 一种用于预防三高的红曲苦瓜复合肽片 - Google Patents
一种用于预防三高的红曲苦瓜复合肽片 Download PDFInfo
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- CN107198767A CN107198767A CN201710358964.7A CN201710358964A CN107198767A CN 107198767 A CN107198767 A CN 107198767A CN 201710358964 A CN201710358964 A CN 201710358964A CN 107198767 A CN107198767 A CN 107198767A
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Abstract
本发明提供了一种用于预防三高的红曲苦瓜复合肽片,包括以下组份:小麦低聚肽粉、大豆肽粉、胶原蛋白肽粉、白蛋白肽粉、聚葡萄糖、低聚异麦芽糖、菊粉、红曲、苦瓜提取物、银杏粉、茶多酚。本产品不仅适口性好,而且对三高患者的症状改善有较为显著的效果。
Description
技术领域
本发明属于一种保健医药领域,具体属于一种用于预防三高的红曲苦瓜复合肽片。
背景技术
“三高症”是指高血压、高血糖(糖尿病)和高脂血症。它们是现代社会所派生出来的“富贵病”,可能单独存在,也可能相互关联。如:糖尿病人很容易同时患上高血压或高血脂症,而高血脂又是动脉硬化形成和发展的主要因素,动脉硬化患者血管弹性差加剧血压升高。所以,出现这三种疾患中的任何一种,后期都易形成了“三高症”。
(一)高血压
高血压病是当代最常见的流行病之一,早期高血压病人可表现头痛、头晕、耳鸣、心悸、眼花、注意力不集中、记忆力减退、手脚麻木、疲乏无力、易烦躁等症状,这些症状多为高级神经功能失调所致,其轻重与血压增高程度可不一致。
后期血压常持续在较高水平,并伴有脑、心、肾等器官受损的表现。这些器官受损可以是高血压直接损害造成的,也可以是间接地通过加速动脉粥样硬化性疾病产生而造成的。这些器官受损的早期可无症状,最后导致功能障碍,甚至发生衰竭。
(二)高血糖
最常见的高血糖症是糖尿病。糖尿病是一种慢性、终生性疾病,是一种严重危害人体健康的常见病,由于胰岛素相对或绝对不足,使体内碳水化合物、脂肪、蛋白质等营养素代谢异常。此病可引起多种并发症,严重时可以引起全身性疾病,使人致残、致盲,甚至致死。糖尿病的症状为“三多一少”,即多尿、多饮、多食及体重下降。高血糖病人要注意控制饮食,低糖低盐,加强锻炼,如果过段时间再查血糖还是高,也应考虑用降血糖的药。
(三)高血脂
高血脂是指血中胆固醇或甘油三酯过高或高密度脂蛋白胆固醇过低,现代医学称之为血脂异常。如果血脂过多,容易造成“血稠”,在血管壁上沉积,逐渐形成动脉粥样硬化,逐渐堵塞血管,使血流变慢,严重时血流中断。
这种情况如果发生在心脏,就会引起冠心病;发生在脑部会出现脑中风;如果堵塞眼底血管,将导致视力下降、失明;如果发生在肾脏,就会引起肾动脉硬化,肾功能衰竭;发生在下肢,会出现肢体坏死、溃烂等。此外,高血脂可引发高血压、诱发胆结石、胰腺炎,加重肝炎、老年痴呆等疾病。要降血脂可多食用维生素C片、银杏软胶囊、液体钙之类的物质。
临床对三高的预防,现在一般用西药降压降糖降脂药,这些药物一般副作用大,往往一旦服用便需终生服用,不能达到标本兼治的目的,而且有些药物还有停药反应,所以,如何利用中医基础理论,结合中药材的优势,发明一种疗效显著、副作用小的中药或保健品成为临床亟需解决的问题。
发明内容
技术问题:本发明针对三高人群的症状,提供一种用于预防三高的红曲苦瓜复合肽片。
技术方案:本发明提供一种用于预防三高的红曲苦瓜复合肽片,包括以下原料:小麦低聚肽粉、大豆肽粉、胶原蛋白肽粉、白蛋白肽粉、聚葡萄糖、低聚异麦芽糖、菊粉、红曲、苦瓜提取物、银杏粉、茶多酚。
作为一种优选,各原料重量配比如下:小麦低聚肽粉15-25份、大豆肽粉15-25份、胶原蛋白肽粉2-6份、白蛋白肽粉1-3份、聚葡萄糖5-9份、低聚异麦芽糖8-12份、菊粉2-5份、红曲3-12份、苦瓜提取物3-12份、银杏粉2-6份、茶多酚0.15-1.25份。
作为进一步优选:各原料重量配比如下:小麦低聚肽粉20份、大豆肽粉20份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份。
有益效果:本配方能够有效预防三高,同时减少服用的不适感,作用缓和,无副作用。
小麦低聚肽粉:可调节人的血糖,改善糖尿病症状,能阻碍血管紧张素酶的作用,具有降血压的效果,含高谷酰胺,能够有效调节神经,可作肠功能障碍时的特殊营养物质。
大豆肽粉:营养丰富、人体易吸收,还具有抗高血压、降低胆固醇、抗血栓形成,改善脂质代谢,促进肌红细胞复原,消除疲劳等调节功能。
胶原蛋白肽粉:可加快血管壁新陈代谢,增加血管壁弹性。
白蛋白肽粉:可维持血浆渗透压、增加血容量。
红曲米提取物:降低胆固醇效果好。
苦瓜提取物:号称植物胰岛素,具有良好的降血糖功效,无毒副作用。
具体实施方式
下面通过实验进一步阐述本发明的有益效果,通过实施例进一步阐述本发明。
本实验原料药品来源厂家及型号如下表:
药品名称 | 生产厂家 |
小麦低聚肽粉 | 山东天久生物技术有限公司 |
大豆肽粉 | 诺利如一(安阳)生物科技有限公司 |
胶原蛋白肽粉 | 山东天久生物技术有限公司 |
白蛋白肽粉 | 山东天久生物技术有限公司 |
聚葡萄糖 | 山东百龙创元生物科技有限公司 |
低聚异麦芽糖 | 山东百龙创元生物科技有限公司 |
菊粉 | 陕西森弗天然制品有限公司 |
苦瓜提取物 | 陕西森弗天然制品有限公司 |
银杏粉 | 陕西森弗天然制品有限公司 |
实施例1
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:小麦低聚肽粉15份、大豆肽粉15份、胶原蛋白肽粉2份、白蛋白肽粉1份、聚葡萄糖5份、低聚异麦芽糖8份、菊粉2份、红曲3份、苦瓜提取物3份、银杏粉2份、茶多酚0.15份。
其制备过程,包括以下步骤:
称取小麦低聚肽粉15份、大豆肽粉15份、胶原蛋白肽粉2份、白蛋白肽粉1份、聚葡萄糖5份、低聚异麦芽糖8份、菊粉2份、红曲3份、苦瓜提取物3份、银杏粉2份、茶多酚0.15份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
实施例2
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:小麦低聚肽粉20份、大豆肽粉20份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份。
其制备过程,包括以下步骤:
称取小麦低聚肽粉20份、大豆肽粉20份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
实施例3
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:小麦低聚肽粉25份、大豆肽粉25份、胶原蛋白肽粉6份、白蛋白肽粉3份、聚葡萄糖9份、低聚异麦芽糖12份、菊粉5份、红曲12份、苦瓜提取物12份、银杏粉6份、茶多酚1.25份。
其制备过程,包括以下步骤:
称取小麦低聚肽粉25份、大豆肽粉25份、胶原蛋白肽粉6份、白蛋白肽粉3份、聚葡萄糖9份、低聚异麦芽糖12份、菊粉5份、红曲12份、苦瓜提取物12份、银杏粉6份、茶多酚1.25份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
对比例1
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:小麦低聚肽粉40份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份。
其制备过程,包括以下步骤:
称取小麦低聚肽粉40份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
对比例2
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:大豆肽粉40份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份。
其制备过程,包括以下步骤:
称取大豆肽粉40份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
对比例3
预防三高的红曲苦瓜复合肽片,各原料重量配比如下:小麦低聚肽粉25份、大豆肽粉25份、胶原蛋白肽粉6份、白蛋白肽粉3份、低聚异麦芽糖12份、菊粉5份、红曲12份、苦瓜提取物12份、银杏粉6份、茶多酚1.25份。
其制备过程,包括以下步骤:
称取小麦低聚肽粉25份、大豆肽粉25份、胶原蛋白肽粉6份、白蛋白肽粉3份、低聚异麦芽糖12份、菊粉5份、红曲12份、苦瓜提取物12份、银杏粉6份、茶多酚1.25份,混合得总混合粉;在总混合粉中加入纯净水,得软材;将软材用40目筛制粒,得湿颗粒;将湿颗粒在60℃干燥至水分<5%,40目筛整粒,得干颗粒;将干颗粒压片,得片剂,600mg/片。
药效学实验
本产品可煎服、泡服、散剂、颗粒、片剂等剂型。
药物试验
一般资料:
取来诊高血压、高血糖、高血脂三高病例500例,年龄在25-75之间,平均年龄53.6岁。
诊断标准
高血脂:参照《中药新药临床研究指导原则》和2007年《中国成人血脂异常防治指南》标准进行评定。
高血压:临床诊断均符合世界卫生组织(WTO)规定的标准,即预防前基础血压大于等于160/95mmHg。
高血糖:参照1999年WTOT2DM诊断标准,中医诊断标准参照《中药新药临床研究指导原则(试行)》中消渴的中医辨证标准。
服用方法
服用本发明实施例1至3和对比例1至3的药物,每次10g,一日2次泡服,分两次服用,1个月为一个疗程,2个疗程后复诊,检查预防效果。
疗效结果
由上表可知:本配方的红曲苦瓜复合肽片在预防三高方面效果显著。
Claims (3)
1.一种用于预防三高的红曲苦瓜复合肽片,其特征在于:包括以下组份:小麦低聚肽粉、大豆肽粉、胶原蛋白肽粉、白蛋白肽粉、聚葡萄糖、低聚异麦芽糖、菊粉、红曲、苦瓜提取物、银杏粉、茶多酚。
2.根据权利要求1所述的一种用于预防三高的红曲苦瓜复合肽片,其特征在于:各组份重量份如下:小麦低聚肽粉15-25份、大豆肽粉15-25份、胶原蛋白肽粉2-6份、白蛋白肽粉1-3份、聚葡萄糖5-9份、低聚异麦芽糖8-12份、菊粉2-5份、红曲3-12份、苦瓜提取物3-12份、银杏粉2-6份、茶多酚0.15-1.25份。
3.根据权利要求1或者2所述的一种用于预防三高的红曲苦瓜复合肽片,其特征在于:各组份重量份如下:小麦低聚肽粉20份、大豆肽粉20份、胶原蛋白肽粉4份、白蛋白肽粉2份、聚葡萄糖7.5份、低聚异麦芽糖9.75份、菊粉3.75份、红曲7.5份、苦瓜提取物7.5份、银杏粉4.5份、茶多酚0.75份。
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