CN106538904A - A kind of relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating and preparation processing method - Google Patents

A kind of relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating and preparation processing method Download PDF

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Publication number
CN106538904A
CN106538904A CN201610234353.7A CN201610234353A CN106538904A CN 106538904 A CN106538904 A CN 106538904A CN 201610234353 A CN201610234353 A CN 201610234353A CN 106538904 A CN106538904 A CN 106538904A
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parts
herba dendrobii
vitis viniferae
fresh
water
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温从字
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Zhejiang Yu Chen Pharmaceutical Co Ltd
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Zhejiang Yu Chen Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Non-Alcoholic Beverages (AREA)

Abstract

The beverage the invention discloses a kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved, is made up of the raw material of following weight portion:New fresh Herba Dendrobii 10-20 parts, Fructus Vitis viniferae 10-20 parts, Radix Ginseng Rubra's 5-15 parts, Radix Salviae Miltiorrhizae 5-15 parts, Lignum Dalbergiae Odoriferae 5-15 parts, Lignum Aquilariae Resinatum 5-15 parts, Typhonium flagelliforme (Lodd.) Blume 5-10 parts, Sanguis Draxoniss 5-15 parts, Rhizoma Pinelliae 5-12 parts, Radix Angelicae Dahuricae 5-15 parts, Radix Angelicae Sinensis 5-16 parts, Pericarpium Trichosanthiss 5-10 parts, Os Draconis 5-15 parts, Massa Medicata Fermentata 5-15 parts, Mel, appropriate amount of water.It is an advantage of the invention that:Inventive formulation with promoting blood circulation, blood stasis dispelling, qi-regulating, the function such as feel relieved, carrying is drunk conveniently, improves body immunity, defying age, eliminating toxin and beautifying the skin, cures the disease while strengthen the beverage of body immunity, and long shelf-life is up to 1-2.

Description

A kind of relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating and preparation processing method
Technical field
The beverage the present invention relates to a kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved, in particular, is to be related to a kind of blood circulation promoting and blood stasis dispelling qi-regulating Relieved drink formula and preparation method thereof technical field.
Background technology
Beverage traditional at present, only focuses on mouthfeel, is of low nutritive value, not with promoting blood circulation, blood stasis dispelling, qi-regulating, relieved, raising people Body immunity, defying age, eliminating toxin and beautifying the skin, nourishes taste, three high drop, the function of preventing and treating the aspect such as diabetes and anti-cancer, anticancer, nothing Method releases the sufferings of customer, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight poor taste, it is impossible to long-term to preserve.Existing market On not yet occur a kind of in good taste, improving itself increases the wriggling of the intestines and stomach, cures the disease while strengthening the beverage of body immunity.
The content of the invention
Deficiency of the present invention for existing product, and provide a kind of fresh juice beverage to adjust the effect of human physiological functions, The beverage have be easily absorbed by the human body, medicinal function significantly, delicious flavour, good mouthfeel, improve itself and increase the wriggling of the intestines and stomach, Cure the disease while a kind of relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating of the advantages of strengthening body immunity.
A kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved beverage, is made up of the raw material of following weight portion:New fresh Herba Dendrobii 10-20 parts, Fructus Vitis viniferae 10-20 parts, Radix Ginseng Rubra's 5-15 parts, Radix Salviae Miltiorrhizae 5-15 parts, Lignum Dalbergiae Odoriferae 5-15 parts, Lignum Aquilariae Resinatum 5-15 parts, Typhonium flagelliforme (Lodd.) Blume 5-10 parts, Sanguis Draxoniss 5-15 Part, Rhizoma Pinelliae 5-12 parts, Radix Angelicae Dahuricae 5-15 parts, Radix Angelicae Sinensis 5-16 parts, Pericarpium Trichosanthiss 5-10 parts, Os Draconis 5-15 parts, Massa Medicata Fermentata 5-15 parts, honeybee Honey, appropriate amount of water;
A kind of preparation processing method of the relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating, comprises the following steps;
A, Herba Dendrobii fresh bar is put in service sink, removes surface clay stain, the fresh bar of screening high-quality Herba Dendrobii dries standby;
B, the Herba Dendrobii for cleaning up fresh bar is put into microwave oven, keeping temperature 50-60 DEG C carries out heating 10 minutes, then takes Go out to be put in rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of fresh bar weight 0.1-0.5 times of Herba Dendrobii for the first time 52-60 DEG C of Chinese liquor, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, the fresh bar of Herba Dendrobii is added The distilled water of weight 2-3 times, second juice extractor time 10-15min, juice extractor rotating speed are 80~100r/s, stand 10min; After carry out third time and squeeze the juice, add the distilled water of fresh bar weight 3-5 times of Herba Dendrobii, time 20-30min, juice extractor rotating speed for 100~ 150r/s, Herba Dendrobii fresh bar juice is separated with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii up to more than 95%, cell damage Rate obtains new fresh Herba Dendrobii juice and the fresh bar fiber of Herba Dendrobii up to more than 80%;The warm water cleaning that new fresh grape is put into 50-60 DEG C again is dry After net, grape pulp, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
The fresh bar juice of C, Herba Dendrobii is put into and is put in pressure pan with grape pulp, keeps pressure 0.5MP, temperature to keep 100-150 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, detached Herba Dendrobii fresh bar fiber and Pericarpium Vitis viniferae are put in unglazed hermetically sealed can, are added in hermetically sealed can fresh equivalent to Herba Dendrobii The distilled water of the Mel and 5-10 times of weight of bar fiber and Pericarpium Vitis viniferae gross weight 20-30%, stirring are smashed to 100 mesh, in 30-35 Sealing preserve 24h at a temperature of DEG C, sterilizing filter, are put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution Pericarpium Vitis viniferae and the fresh bar fiber of Herba Dendrobii add mass volume ratio for the cellulase of 0.5-0.7%, addition 1:The water of 10 mass ratio, Kept for 35 DEG C, water soluble dietary fiber can be further extracted after 24h enzymolysis, water soluble dietary fiber is added into Matrix Solution Obtain Matrix Solution II;
E, take Radix Ginseng Rubra, Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae, Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxoniss, the Rhizoma Pinelliae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Pericarpium Trichosanthiss, Os Draconis, Massa Medicata Fermentata After mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, be put in reach in freezer, 10-20 minutes freezed at -10~-20 DEG C, formed Freezing medicine block is added water to cook extraction 3 times by freezing medicine block, adds 1-2 times to measure water for the first time, and temperature is kept for 100-120 DEG C, endured Boil 10-20 minutes;4-6 times is added for second to measure water, temperature is kept for 80-100 DEG C, carries out infusion 10 minutes;Third time adds 6-10 times Amount water, temperature are kept for 120-150 DEG C, carry out infusion 30 minutes, are filtered, are concentrated into the 1/2 of original volume, obtain Matrix Solution III It is standby;
F, Matrix Solution I is taken through 110-130 DEG C of instantaneous high-temperature, 1-2 minutes, be put in material-compound tank;Take Matrix Solution II Jing mesh Number is to be put in material-compound tank after the fine filter of 100 mesh is filtered;Take Matrix Solution III again to be put into Jing after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae Jing vacuum outgass, then using CO2 supercritical fluid extractions, the condition of CO2 supercritical fluid extractions is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae in material-compound tank, load in vial through bottle capper sealing, Packaged vial is put into 100~120 DEG C of temperature, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
Further:Step B) in, after new fresh grape is cleaned up, be put in reach in freezer, 5-10 is freezed at -10~-20 DEG C Minute, make Fructus Vitis viniferae freeze, after taking out naturally to thaw, then carry out grape pulp and Pericarpium Vitis viniferae detached job.
Further:Step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae Weight proportion be 10:0.2~0.8:5~10:0.5.
Radix Ginseng Rubra, QI invigorating, YIN nourishing, beneficial blood, promote the production of body fluid, heart tonifying, stomach invigorating, it is calm the effects such as.
Radix Salviae Miltiorrhizae, with blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle the effect of.
Lignum Dalbergiae Odoriferae, promoting flow of QI and blood, pain relieving, hemostasis.Can be used for epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, outer Hinder bleeding.
Lignum Aquilariae Resinatum, acrid in the mouth, hardship are warm in nature;Returns spleen, stomach, kidney channel;Gas perfume row dissipates, and drops and can rise;With circulation of qi promoting warming middle-JIAO to send down the adverse QI, warm up Effect of kidney helping inspiration to relieve asthma.
Typhonium flagelliforme (Lodd.) Blume, enriches blood, invigorates blood circulation, for physical weakness, inappetence, neurasthenia, fatigue.
Sanguis Draxoniss, analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, expelling pus and promoting granulation.
The Rhizoma Pinelliae, enters lung, spleen, three Jing of stomach, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
The Radix Angelicae Dahuricae, expelling pathogenic wind from the body surface, dispersing cold for relieving pain, the sensible, detumescence and apocenosis of dehumidifying.
Radix Angelicae Sinensis, sweet, pungent, warm, Return liver, the heart, spleen channel, enrich blood;Promoting blood circulation;Menstruction regulating and pain relieving;Moisturize laxation.
Pericarpium Trichosanthiss, Qinghua heat-phlegm, promoting the circulation of QI the chest stuffiness relieving, for phlegm-heat cough, hypochondriac pain uncomfortable in chest.
Os Draconis, tranquilizing mind, arresting collape syndrome by astringents, the work(of astringent or styptic treatment for spontaneous sweating lower vital essence.
Massa Medicata Fermentata, invigorating the spleen and regulating the stomach help digestion in tune, for weakness of the spleen and stomach, retention of food and drink.
By more than have multiple health care natural traditional medicinal and edible Chinese medicine share, with promoting blood circulation, blood stasis dispelling, qi-regulating, Feel relieved, improve body immunity the effect of, with the stagnation of QI uncomfortable in chest, blood stasis, dim body of the tongue purple, blood supply insufficiency, weak, loss of appetite it Work(.The proportioning of each component is screened by many experiments, it is scientific and reasonable;And whole preparation technology is rationally and extract drugs rate efficiency Height, can retain the effective ingredient in raw material well, not bring any impurity into, have no toxic side effect.
The invention has the beneficial effects as follows:
1st, formula of the invention, has promoting the production of body fluid to quench thirst, and gastric acid secretion is helped digest, and health body-building declines with calm nerves It is weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., support to improving body immunity, defying age, toxin expelling Face, nourishes taste, three high drop, to prevent and treat the aspect such as diabetes and anti-cancer, anticancer all powerful, adjusts human physiological functions.
2nd, the present invention is rich in anthocyanidin, can protect human body from the damage of free radical, can strengthen blood vessel elasticity, relax Blood vessel, increases systemic blood circulation, with certain blood pressure reduction effect;Immune system ability can be strengthened, with strong anti-oxidation, resisted The functions such as mutation, mitigation hepatosiss, protection cardiovascular;
3rd, add Radix Ginseng Rubra, Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae, Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxoniss, the Rhizoma Pinelliae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Pericarpium Trichosanthiss, Os Draconis, six refreshing The Chinese herbal medicine such as song have the function such as promoting blood circulation, blood stasis dispelling, qi-regulating, relieved.
4th, the products taste that production technology and preparation method of the invention draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has Very high health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and Carrying is drunk conveniently, and improving itself increases the wriggling of the intestines and stomach, cures the disease while strengthening the beverage of body immunity, long shelf-life reaches 1- 2 years.
Specific embodiment
The present invention is further described with reference to specific embodiment, so that those skilled in the art knows more about The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved beverage, is made up of the raw material of following weight portion:It is new 15 parts of fresh Herba Dendrobii, 15 parts of Fructus Vitis viniferae, red 10 parts of Radix Ginseng, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of Lignum Dalbergiae Odoriferae, 10 parts of Lignum Aquilariae Resinatum, 10 parts of Typhonium flagelliforme (Lodd.) Blume, 10 parts of Sanguis Draxoniss, 10 parts of the Rhizoma Pinelliae, 10 parts of the Radix Angelicae Dahuricae, 10 parts of Radix Angelicae Sinensis, 10 parts of Pericarpium Trichosanthiss, 10 parts of Os Draconis, 10 parts of Massa Medicata Fermentata, Mel, appropriate amount of water;
A kind of preparation processing method of the relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating, the preparation method are comprised the following steps;
A, Herba Dendrobii fresh bar is put in service sink, removes surface clay stain, the fresh bar of screening high-quality Herba Dendrobii dries standby;
The Herba Dendrobii for cleaning up fresh bar is put into microwave oven by B, and keeping temperature 50-60 DEG C carries out heating 10 minutes, further takes out It is put in rotating centrifugal juice extractor, carries out three times and squeeze the juice, adds the alcohol content 52 of fresh bar weight 0.1-0.5 times of Herba Dendrobii for the first time DEG C Chinese liquor, time 15min, the rotating speed of juice extractor are 30r/s;After standing 10 minutes, the steaming of 2.5 times of the fresh bar weight of Herba Dendrobii is added Distilled water, second juice extractor time 15min, juice extractor rotating speed are 80r/s, stand 10min;After carry out third time squeeze the juice, add The distilled water of fresh bar weight 3-5 times of Herba Dendrobii, time 30min, juice extractor rotating speed are 150r/s, by Herba Dendrobii fresh bar juice and fiber mistake Filter is separated, and makes the fiber separation rate of the fresh bar of Herba Dendrobii up to more than 95%, broken cell rate up to more than 80%, obtain new fresh Herba Dendrobii juice and The fresh bar fiber of Herba Dendrobii;After again clean up the warm water that new fresh grape is put into 55 DEG C, grape pulp, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated It is stand-by;After new fresh grape is cleaned up, it is put in reach in freezer, freezes 10 minutes at -10 ~ -20 DEG C, make Fructus Vitis viniferae freeze, takes out certainly After so thawing, then carry out grape pulp, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The fresh bar juice of C, Herba Dendrobii is put into and is put in pressure pan with grape pulp, keeps pressure 0.5MP, temperature to keep 120 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, detached Herba Dendrobii fresh bar fiber and Pericarpium Vitis viniferae are put in unglazed hermetically sealed can, are added in hermetically sealed can fresh equivalent to Herba Dendrobii The distilled water of the Mel and 6 times of weight of bar fiber and Pericarpium Vitis viniferae gross weight 20-30%, stirring are smashed to 100 mesh, warm at 30-35 DEG C Lower sealing preserve 24h of degree, sterilizing filter, are put into unglazed hermetically sealed can, obtain Matrix Solution standby;Extract the Fructus Vitis viniferae after Matrix Solution Skin and the fresh bar fiber of Herba Dendrobii add mass volume ratio for the cellulase of 0.5-0.7%, addition 1:The water of 10 mass ratio, keeps , water soluble dietary fiber can be further extracted after 24h enzymolysis, water soluble dietary fiber addition Matrix Solution is obtained by 35 DEG C Matrix Solution II;;In Pericarpium Vitis viniferae be rich in anthocyanidin, human body can be protected from the damage of free radical, can strengthen blood vessel elasticity, Lax blood vessel, increases systemic blood circulation, with certain blood pressure reduction effect;Immune system ability can be strengthened, with strong antioxygen The functions such as change, mutation, mitigation hepatosiss, protection cardiovascular, Pericarpium Vitis viniferae and the fresh bar fiber of Herba Dendrobii are stirred together and smash Jing Hydromel lifts anthocyanidin, and the quality of anthocyanidin can be protected while can farthest extracting anthocyanidin.By water solublity meals Food fiber adds Matrix Solution to obtain Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged In vitro;Adsorb various metabolic wastes, be allowed to normally excrete, improve the comprehensive utilization value of Herba Dendrobii.
E, take Radix Ginseng Rubra, Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae, Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxoniss, the Rhizoma Pinelliae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Pericarpium Trichosanthiss, Os Draconis, six After Massa Medicata Fermentata mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, it is put in reach in freezer, freezes 20 minutes at -10~-20 DEG C, shape Into freezing medicine block, freezing medicine block is added water to cook into extraction 3 times, add 1-2 times to measure water for the first time, temperature is kept for 100-120 DEG C, carried out Infusion 10-20 minutes;Second plus 6 times of amount water, temperature are kept for 80-100 DEG C, carry out infusion 10 minutes;Third time adds 6-10 times Amount water, temperature are kept for 120-150 DEG C, carry out infusion 30 minutes, are filtered, are concentrated into the 1/2 of original volume, obtain Matrix Solution III It is standby;Chinese medicine it is foamed it is good after after freezing, cell wall crystallization rupture forms freezing medicine block, then Jing high temperature infusions makes Chinese medicine Composition farthest extract.
F, Matrix Solution I is taken through 120 DEG C of instantaneous high-temperature, 1-2 minutes, be put in material-compound tank;Take Matrix Solution II Jing mesh Number is to be put in material-compound tank after the fine filter of 100 mesh is filtered;Take Matrix Solution III again to be put into Jing after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae Jing vacuum outgass, then using CO2 supercritical fluid extractions, the condition of CO2 supercritical fluid extractions is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;Supercritical extraction can be It is close under 37 DEG C of room temperature and CO2 gas blankets and is extracted, effectively prevent the oxidation and loss of heat-sensitive substance.Therefore, The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the material being easily pyrolyzed remote low Extract under its boiling temperature;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae in material-compound tank, and the material-compound tank endobasal-body solution I, matrix are molten Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., load vial through bottle capper sealing In, packaged vial is put into 100~120 DEG C of temperature, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, dress Case, carrying are drunk conveniently, and long shelf-life reaches 1-2.
Embodiment 2
A kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved beverage, is made up of the raw material of following weight portion:It is made up of the raw material of following weight portion:By The raw material of following weight portion is made:New 10 parts of fresh Herba Dendrobii, 10 parts of Fructus Vitis viniferae, 5 parts of Radix Ginseng Rubra, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of Lignum Dalbergiae Odoriferae, 5 parts of Lignum Aquilariae Resinatum, 5 parts of Typhonium flagelliforme (Lodd.) Blume, 5 parts of Sanguis Draxoniss, 5 parts of the Rhizoma Pinelliae, 5 parts of the Radix Angelicae Dahuricae, 5 parts of Radix Angelicae Sinensis, 5 parts of Pericarpium Trichosanthiss, 5 parts of Os Draconis, 5 parts of Massa Medicata Fermentata, Mel, Appropriate amount of water;Processing method is with embodiment 1.
Embodiment 3
A kind of blood circulation promoting and blood stasis dispelling qi-regulating is felt relieved beverage, is made up of the raw material of following weight portion:It is made up of the raw material of following weight portion:Newly 20 parts of fresh Herba Dendrobii, 20 parts of Fructus Vitis viniferae, 15 parts of Radix Ginseng Rubra, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of Lignum Dalbergiae Odoriferae, 15 parts of Lignum Aquilariae Resinatum, 10 parts of Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxoniss 15 Part, 12 parts of the Rhizoma Pinelliae, 15 parts of the Radix Angelicae Dahuricae, 16 parts of Radix Angelicae Sinensis, 10 parts of Pericarpium Trichosanthiss, 15 parts of Os Draconis, 15 parts of Massa Medicata Fermentata, Mel, appropriate amount of water;Processing Method is with embodiment 1.
Three parts of clinical experiment point:
(One)Animal acute toxicity and chronic toxicity experiment:
1st, animal acute toxicity test
Medicine:The embodiment of the present invention 1, embodiment 2 and 3 medicated tea of embodiment add medicated tea paste mixing made by rice flour.
Experimental animal:Regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of medicated tea each 50g, rice flour is added.Experiment mice is randomly divided into into three groups of male and female half and half, respectively three kinds of medicated tea of feeding Paste mixing, volume 1ml/10g body weight, close observation 8 hours are simultaneously noted down, and continue observation 7 days;In 7 days, mice without death, OK For active, food ration is as usual, hair color light without loose dirt, without addicted to saliva, eye, mouth, nose, ear and crissum secretions without exception of fainting from fear, Without the rotten toe that docks.From three groups 5 are selected to put to death respectively, finding of naked eye:The important organs such as the heart, liver, lung, gastric and thymus, not See abnormal change, show two kinds of nutritive powders without acute toxicity.
2nd, long-term toxicity test for animals
Medicine:The embodiment of the present invention 1, embodiment 2 and 3 gained medicated tea of embodiment add medicated tea paste mixing made by rice flour.
Animal:Regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration of three kinds of medicated tea paste mixings:Be divided into high, medium and low three dosage groups, respectively edible for patients amount 200,100, 50g;Experimental mouse is randomly divided into into three groups, the medicated tea paste mixing that continuous feeding is modulated respectively, continuous feeding 40 days observe animal General toxic reaction and the order of severity, place after death check each position by rule of operation, and carry out hematology, ALT, BUN and the heart, The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach;
Through long-term feeding, there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no It is abnormal.Peripheral hemogram and Serum ALT, BUN are compared with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach Deng not significant change, it is understood that Jing proved by pathology, three kinds of medicated tea paste mixings are to animal without chronic toxicity performance.
By two above toxicity test, it was demonstrated that the present invention by embodiment 1, embodiment 2 and embodiment 3 make medicated tea be Safety, have no toxic side effect, can be used to clinical trial be carried out to clinical patients.
3rd, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. drink crowd:General population
2. Ganderwa:30 days
3. drink number:50 people
4. drinking method:3 times for each person every day, each 300mL
5. index:Easily tired, the uncomfortable in chest stagnation of QI, blood stasis, dim body of the tongue purple, blood supply insufficiency, weak, appetite are substantially felt after drinking Go down, dyspepsia, anorexia, middle gas are not saved etc., and symptom disappears, and mouthfeel is clear sour-sweet for effective;Feel after drinking easily tired Labor, the stagnation of QI uncomfortable in chest, blood stasis, dim body of the tongue purple, blood supply insufficiency, weak, loss of appetite;Dyspepsia, anorexia, middle gas do not save disease Shape is alleviated, and mouthfeel is clear sour-sweet, is designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2)Survey result
Survey result is shown in Table 1.By table 1 test result indicate that, embodiment 1,2,3 have 98% respondent feel the present invention carried For beverage mouthfeel it is sour-sweet clearly, and above-mentioned clinical symptom disappearance or be eased, only 2% respondent drink after without substantially Increase comfort.
1 each embodiment of table drinks effect research table
Group/effect Obvious effective rate(Number) Effective percentage(Number) Inefficiency(Number)
Embodiment 1 44%(22) 54%(27) 2%(1)
Embodiment 2 42%(21) 56%(28) 2%(1)
Embodiment 3 42%(21) 56%(28) 2%(1)
Embodiment contrast groups A
Comparative example 4,5,6 be added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae into Point, according to the original raw material in the Chinese medicine part of embodiment 1,2,3 above, preparation for processing is traditional side of boiling Method;The investigation method of using method and using effect is with above.
2 embodiment contrast groups A of table drink effect research
Group/effect Obvious effective rate(Number) Effective percentage(Number) Inefficiency(Number)
Comparative example 4 36%(18) 40%(20) 24%(12)
Comparative example 5 40%(20) 40%(20) 20%(10)
Comparative example 6 46%(23) 34%(17) 20%(10)
Embodiment contrast groups B
Comparative example 7,8,9 be added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae into Point, according to the original raw material in the Chinese medicine part of embodiment 1,2,3 above, preparation for processing is using in embodiment 1 The preparation processing method of step E;The investigation method of using method and using effect is with above.
3 embodiment contrast groups B of table drink effect research
Group/effect Obvious effective rate(Number) Effective percentage(Number) Inefficiency(Number)
Comparative example 7 32%(16) 56%(28) 12%(6)
Comparative example 8 28%(14) 52%(31) 10%(5)
Comparative example 9 36%(18) 52%(26) 12%(6)
Conclusion:
Can be seen that by table 2 and the contrast of table 1:
10 times or so for embodiment 1,2,3 of the inefficient number of embodiment contrast groups A;This shows Chinese crude drug formula of the present invention The pharmacological action of mutual collaboration is generated and the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae between, aqueous soluble dietary is fine Dimension increases effect of the wriggling of the intestines and stomach and promotes absorption of the human body to ingredient, it is ensured that metabolic waste is normally excreted, in addition The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, with strong anti-oxidation, mutation, mitigate hepatosiss, protection cardiovascular etc. Function, strengthens immune system ability;Associate with Chinese medicine and assimilation effect is improved while improving the mouthfeel of Chinese medicine, through the essence of the present invention The heart is configured and the at utmost extraction of ingredient, and Chinese crude drug formula of the present invention and preparation method occur in that beat all technology Effect.
Table 2 and the contrast of table 3 can be seen that:
The inefficient number of embodiment contrast groups A is 2 times or so of embodiment contrast groups B, embodiment contrast groups B and traditional Embodiment contrast groups A of boiling method have compared significant raising in therapeutic effect, and this shows Chinese crude drug of the present invention through step Than traditional boiling method, the extraction degree of active ingredient has huge raising to the preparation processing method of rapid E.
In sum, the relieved beverage of a kind of blood circulation promoting and blood stasis dispelling qi-regulating that the present invention is provided has sour-sweet mouthfeel, while and having Have treatment easily tired, the uncomfortable in chest stagnation of QI, blood stasis, dim body of the tongue purple, blood supply insufficiency, weak, loss of appetite, dyspepsia, do not think drink Food, the work(that do not save of middle gas, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishes taste, three high drop, prevent and treat diabetes and anti- The aspects such as cancer, anticancer are all powerful.And all raw materials are all from medicine-food two-purpose natural plants, have no toxic side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (6)

1. a kind of blood circulation promoting and blood stasis dispelling qi-regulating feel relieved beverage, it is characterised in that be made up of the raw material of following weight portion:New fresh Herba Dendrobii 10- 20 parts, Fructus Vitis viniferae 10-20 parts, Radix Ginseng Rubra's 5-15 parts, Radix Salviae Miltiorrhizae 5-15 parts, Lignum Dalbergiae Odoriferae 5-15 parts, Lignum Aquilariae Resinatum 5-15 parts, Typhonium flagelliforme (Lodd.) Blume 5-10 parts, Sanguis Draxoniss 5-15 parts, Rhizoma Pinelliae 5-12 parts, Radix Angelicae Dahuricae 5-15 parts, Radix Angelicae Sinensis 5-16 parts, Pericarpium Trichosanthiss 5-10 parts, Os Draconis 5-15 parts, Massa Medicata Fermentata 5-15 parts, Mel, appropriate amount of water;
A kind of preparation processing method of the relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating, comprises the following steps;
A, Herba Dendrobii fresh bar is put in service sink, removes surface clay stain, the fresh bar of screening high-quality Herba Dendrobii dries standby;
B, the Herba Dendrobii for cleaning up fresh bar is put into microwave oven, keeping temperature 50-60 DEG C carries out heating 10 minutes, then takes Go out to be put in rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of fresh bar weight 0.1-0.5 times of Herba Dendrobii for the first time 52-60 DEG C of Chinese liquor, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, the fresh bar of Herba Dendrobii is added The distilled water of weight 2-3 times, second juice extractor time 10-15min, juice extractor rotating speed are 80~100r/s, stand 10min; After carry out third time and squeeze the juice, add the distilled water of fresh bar weight 3-5 times of Herba Dendrobii, time 20-30min, juice extractor rotating speed for 100~ 150r/s, Herba Dendrobii fresh bar juice is separated with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii up to more than 95%, cell damage Rate obtains new fresh Herba Dendrobii juice and the fresh bar fiber of Herba Dendrobii up to more than 80%;The warm water cleaning that new fresh grape is put into 50-60 DEG C again is dry After net, grape pulp, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
The fresh bar juice of C, Herba Dendrobii is put into and is put in pressure pan with grape pulp, keeps pressure 0.5MP, temperature to keep 100-150 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, detached Herba Dendrobii fresh bar fiber and Pericarpium Vitis viniferae are put in unglazed hermetically sealed can, are added in hermetically sealed can fresh equivalent to Herba Dendrobii The distilled water of the Mel and 5-10 times of weight of bar fiber and Pericarpium Vitis viniferae gross weight 20-30%, stirring are smashed to 100 mesh, in 30-35 Sealing preserve 24h at a temperature of DEG C, sterilizing filter, are put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution Pericarpium Vitis viniferae and the fresh bar fiber of Herba Dendrobii add mass volume ratio for the cellulase of 0.5-0.7%, addition 1:The water of 10 mass ratio, Kept for 35 DEG C, water soluble dietary fiber can be further extracted after 24h enzymolysis, water soluble dietary fiber is added into Matrix Solution Obtain Matrix Solution II;
E, take Radix Ginseng Rubra, Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae, Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxoniss, the Rhizoma Pinelliae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Pericarpium Trichosanthiss, Os Draconis, six refreshing It is bent;After mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, be put in reach in freezer, 10-20 minutes are freezed at -10~-20 DEG C, Freezing medicine block is added water to cook extraction 3 times by formation freezing medicine block, adds 1-2 times to measure water for the first time, and temperature is kept for 100-120 DEG C, entered Row infusion 10-20 minutes;4-6 times is added for second to measure water, temperature is kept for 80-100 DEG C, carries out infusion 10 minutes;Third time plus 6- 10 times of amount water, temperature are kept for 120-150 DEG C, carry out infusion 30 minutes, filtered, be concentrated into the 1/2 of original volume, obtain Matrix Solution III is standby;
F, Matrix Solution I is taken through 110-130 DEG C of instantaneous high-temperature, 1-2 minutes, be put in material-compound tank;Take Matrix Solution II Jing mesh Number is to be put in material-compound tank after the fine filter of 100 mesh is filtered;Take Matrix Solution III again to be put into Jing after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae Jing vacuum outgass, then using CO2 supercritical fluid extractions, the condition of CO2 supercritical fluid extractions is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae in material-compound tank, load in vial through bottle capper sealing, Packaged vial is put into 100~120 DEG C of temperature, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
2. a kind of blood circulation promoting and blood stasis dispelling qi-regulating according to claim 1 feel relieved beverage, it is characterised in that step B) in, fresh Portugal After grape clean up, be put in reach in freezer, 5-10 minutes are freezed at -10~-20 DEG C, make Fructus Vitis viniferae freeze, after taking out naturally to thaw, Grape pulp, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job are carried out again.
3. a kind of blood circulation promoting and blood stasis dispelling qi-regulating according to claim 1 feel relieved beverage, it is characterised in that step H) described in dispensing Tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.2~0.8:5~10: 0.5。
4. a kind of blood circulation promoting and blood stasis dispelling qi-regulating according to claim 1 feel relieved beverage, it is characterised in that by the original of following weight portion Material is made:New 15 parts of fresh Herba Dendrobii, 15 parts of Fructus Vitis viniferae, 10 parts of Radix Ginseng Rubra, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of Lignum Dalbergiae Odoriferae, 10 parts of Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume 10 Part, 10 parts of Sanguis Draxoniss, 10 parts of the Rhizoma Pinelliae, 10 parts of the Radix Angelicae Dahuricae, 10 parts of Radix Angelicae Sinensis, 10 parts of Pericarpium Trichosanthiss, 10 parts of Os Draconis, 10 parts of Massa Medicata Fermentata, Mel, Appropriate amount of water.
5. a kind of blood circulation promoting and blood stasis dispelling qi-regulating according to claim 1 feel relieved beverage, it is characterised in that by the original of following weight portion Material is made:New 10 parts of fresh Herba Dendrobii, 10 parts of Fructus Vitis viniferae, 5 parts of Radix Ginseng Rubra, 5 parts of Radix Salviae Miltiorrhizae, 5 parts of Lignum Dalbergiae Odoriferae, 5 parts of Lignum Aquilariae Resinatum, 5 parts of Typhonium flagelliforme (Lodd.) Blume, Sanguis Draxonis Spend 5 parts, 5 parts of the Rhizoma Pinelliae, 5 parts of the Radix Angelicae Dahuricae, 5 parts of Radix Angelicae Sinensis, 5 parts of Pericarpium Trichosanthiss, 5 parts of Os Draconis, 5 parts of Massa Medicata Fermentata, Mel, appropriate amount of water.
6. a kind of blood circulation promoting and blood stasis dispelling qi-regulating according to claim 1 feel relieved beverage, it is characterised in that by the original of following weight portion Material is made:New 20 parts of fresh Herba Dendrobii, 20 parts of Fructus Vitis viniferae, 15 parts of Radix Ginseng Rubra, 15 parts of Radix Salviae Miltiorrhizae, 15 parts of Lignum Dalbergiae Odoriferae, 15 parts of Lignum Aquilariae Resinatum, Typhonium flagelliforme (Lodd.) Blume 10 Part, 15 parts of Sanguis Draxoniss, 12 parts of the Rhizoma Pinelliae, 15 parts of the Radix Angelicae Dahuricae, 16 parts of Radix Angelicae Sinensis, 10 parts of Pericarpium Trichosanthiss, 15 parts of Os Draconis, 15 parts of Massa Medicata Fermentata, Mel, Appropriate amount of water.
CN201610234353.7A 2016-04-17 2016-04-17 A kind of relieved beverage of blood circulation promoting and blood stasis dispelling qi-regulating and preparation processing method Pending CN106538904A (en)

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