Weaned pig nutritional premix for replacing antibiotics to reduce diarrhea of weaned pigs
Technical Field
The invention relates to the technical field of pig feed nutrition, in particular to a weaned pig nutrition premix for replacing antibiotics to reduce diarrhea of weaned pigs.
Background
About 8 hundred million piglets are born every year in China, but only 7 hundred million pork pigs are finally slaughtered, nearly 1 hundred million pork pigs exist, and about 10 percent of piglets die due to diarrhea, so the loss is very large. After the piglets are weaned, the maternal antibodies are not supplied, the active immunity of the piglets is not well established, the piglets are very easily affected by diseases, meanwhile, the piglets grow and develop rapidly, the requirements on nutrition are high, but the digestion and absorption functions of the piglets are weak, the immunity function is low, and the requirements on external environmental conditions such as temperature are high. The piglets are in the period of high disease occurrence in the whole pig raising period and are also in the period of more medicine contact in the health care, prevention and treatment, and the elimination or death of a plurality of piglets is closely related to improper medication. The digestive system of the piglets is not mature, the digestive capacity of the solid feed is limited, and in addition, the domestic hurdle conditions are simple and crude and the influence of peripheral epidemic diseases is caused, and the piglets often have diarrhea and other disease conditions. The use of antibiotics in large dose seriously affects the immune system and growth development of weaned pigs, causes immunosuppression and growth retardation, and also causes the problems of antibiotic abuse and drug resistance, thereby affecting the healthy and continuous development of the whole pig industry.
How to screen out a nutrition technology capable of improving the immunity, the digestibility and the disease resistance of the feed for the piglets by integrating the nutrition technology to replace antibiotics so as to achieve the purposes of preventing diarrhea and promoting the growth of the piglets is a technical problem in the pig industry.
Disclosure of Invention
The invention aims to provide a weaned pig nutritional premix for replacing antibiotics to reduce diarrhea of a weaned pig.
The purpose of the invention is realized by the following technical scheme:
the weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pigs is prepared from the following raw materials in parts by weight: 3-15 parts of compound probiotics, 1-5 parts of cecropin antibacterial peptide, 1-8 parts of plant essential oil, 1-8 parts of complex enzyme preparation, 20-60 parts of compound acidifier, 1-8 parts of organic iron, 1-8 parts of organic copper, 1-8 parts of nano zinc oxide, 1-8 parts of chitosan oligosaccharide, 1-5 parts of vitamin D31, 1-8 parts of vitamin C, 5-30 parts of glutamine, 1-8 parts of antioxidant and 20-150 parts of crushed corn flour.
Preferably: 5-10 parts of compound probiotics, 2-3 parts of cecropin antimicrobial peptide, 2-5 parts of plant essential oil, 3-6 parts of complex enzyme preparation, 30-50 parts of compound acidifier, 2-4 parts of organic iron, 1-4 parts of organic copper, 2-4 parts of nano zinc oxide, 3-6 parts of chitosan oligosaccharide, 3-3 parts of vitamin D31, 3-6 parts of vitamin C, 5-20 parts of glutamine, 2-4 parts of antioxidant and 30-120 parts of crushed corn flour.
The compound enzyme preparation is formed by mixing β -xylanase 0.2-2 parts, β -glucanase 0.2-2 parts, protease 0.2-2 parts, α -amylase 0.2-2 parts and phytase 0.2-2 parts.
The compound acidulant is prepared by mixing 3-15 parts of lactic acid, 3-15 parts of phosphoric acid, 3-15 parts of citric acid, 3-15 parts of malic acid and 3-15 parts of tartaric acid.
The composite probiotics is prepared by mixing 1-5 parts of clostridium butyricum, 1-5 parts of bacillus coagulans and 1-5 parts of bacillus licheniformis.
The antioxidant is ethoxyquinoline;
the organic iron is one or more of porphyrin iron, ferrous fumarate and ferric glycinate;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 0.3-3 parts of origanum oil, 0.3-3 parts of thyme oil and 0.3-3 parts of cinnamon oil.
When in use, 1-5 parts of weaned pig nutritional premix is added into 100 parts of complete feed.
The nutritional premix for the weaned piglets can replace antibiotics to reduce diarrhea of the weaned piglets.
The anti-diarrhea effect of antibiotics is mainly due to the inhibition of negative bacteria. On the basis of researching the traditional pig feed nutrition formula, the invention screens various formulas, screens out the nutritional weaned pig nutritional premix capable of improving the immunity, feed digestibility, disease resistance and the like of piglets by integrating nutrition technologies, replaces antibiotics, and achieves the effect equivalent to or even superior to the antibiotics on the premise of not using the antibiotics: wherein the combination of plant essential oil, cecropin antibacterial peptide and composite probiotics has antibacterial effect; the combination of the nano zinc oxide and the organic copper plays roles in convergence and diarrhea prevention; the combination of the composite probiotics and the glutamine plays a vital role in the healthy development of intestinal tracts and the stable flora; the chitosan oligosaccharide, organic iron, vitamin D3 and vitamin C are used for improving the immunity and the anti-stress capability of piglets; the combination of the complex enzyme preparation, the complex acidifier and the complex probiotics can obviously improve the digestion capability of piglets. According to the invention, through scientific compatibility of the components, the intestinal flora of the piglets can be improved, the immunity, the feed digestibility and the antiviral capacity of the piglets are improved, and the antibiotics are effectively replaced to prevent and treat the diarrhea of the piglets.
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pigs provided by the invention has the following advantages:
1. the nutritional premix for the weaned pigs has a reasonable formula and is suitable for the growth, development and physiological characteristics of the weaned pigs.
2. The weaned piglet nutritional premix is innovative in formula, can remarkably improve intestinal flora of piglets after being applied, improves immunity, feed digestibility and antiviral capacity of the piglets, and effectively replaces antibiotics to prevent and treat diarrhea of the piglets.
3. The weaned pig nutritional premix has low cost and conforms to the actual production of a pig farm.
Detailed Description
The invention is further illustrated by the following examples. It should be understood that the examples of the present invention are for illustrative purposes and not intended to limit the present invention. Simple modifications of the invention in accordance with its spirit fall within the scope of the claimed invention.
Example 1
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pig is prepared from the following raw materials in parts by weight: 3g of compound probiotics, 1g of cecropin antibacterial peptide, 1g of plant essential oil, 1g of compound enzyme preparation, 20g of compound acidifier, 1g of organic iron, 1g of organic copper, 1g of nano zinc oxide, 1g of chitosan oligosaccharide, vitamin D31 g, 1g of vitamin C, 5g of glutamine, 1g of antioxidant and 20g of crushed corn flour.
The compound enzyme preparation is prepared by mixing β -xylanase 0.2g, β -glucanase 0.2g, protease 0.2g, α -amylase 0.2g and phytase 0.2 g.
The compound acidulant is prepared by mixing 3g of lactic acid, 3g of phosphoric acid, 5g of citric acid, 5g of malic acid and 4g of tartaric acid.
The composite probiotics is prepared by mixing 1g of clostridium butyricum, 1g of bacillus coagulans and 1g of bacillus licheniformis.
The antioxidant is ethoxyquinoline;
the organic iron is porphyrin iron and ferrous fumarate;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 0.3g of oregano oil, 0.3g of thyme oil and 0.4g of cinnamon oil.
When in use, 10g of weaned pig nutritional premix is added into 1kg of complete feed.
Example 2
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pig is prepared from the following raw materials in parts by weight: 15g of compound probiotics, 5g of cecropin antimicrobial peptide, 8g of plant essential oil, 8g of compound enzyme preparation, 60g of compound acidifier, 8g of organic iron, 8g of organic copper, 8g of nano zinc oxide, 8g of chitosan oligosaccharide, 35 g of vitamin D, 8g of vitamin C, 30g of glutamine, 8g of antioxidant and 150g of crushed corn flour.
The compound enzyme preparation is prepared by mixing β -xylanase 1g, β -glucanase 2g, protease 2g, α -amylase 1g and phytase 2 g.
The compound acidifier is prepared by mixing 15g of lactic acid, 10g of phosphoric acid, 12g of citric acid, 12g of malic acid and 11g of tartaric acid.
The composite probiotics is prepared by mixing 5g of clostridium butyricum, 5g of bacillus coagulans and 5g of bacillus licheniformis.
The antioxidant is ethoxyquinoline;
the organic iron is a mixture of porphyrin iron, ferrous fumarate and ferric glycinate;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 3g of oregano oil, 3g of thyme oil and 2g of cinnamon oil.
When in use, 50g of weaned pig nutritional premix is added into 1kg of complete feed.
Example 3
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pig is prepared from the following raw materials in parts by weight: 5g of compound probiotics, 2g of cecropin antimicrobial peptide, 2g of plant essential oil, 3g of compound enzyme preparation, 30g of compound acidifier, 2g of organic iron, 1g of organic copper, 2g of nano zinc oxide, 3g of chitosan oligosaccharide, vitamin D31 g, 3g of vitamin C, 5g of glutamine, 2g of antioxidant and 30g of crushed corn flour.
The compound enzyme preparation is prepared by mixing β -xylanase 0.5g, β -glucanase 1g, protease 0.5g, α -amylase 0.5g and phytase 0.5 g.
The compound acidulant is prepared by mixing 5g of lactic acid, 6g of phosphoric acid, 8g of citric acid, 5g of malic acid and 6g of tartaric acid.
The composite probiotics is prepared by mixing 2g of clostridium butyricum, 2g of bacillus coagulans and 1g of bacillus licheniformis. The antioxidant is ethoxyquinoline;
the organic iron is porphyrin iron;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 0.5g of oregano oil, 1g of thyme oil and 0.5g of cinnamon oil.
When in use, 20g of weaned pig nutritional premix is added into 1kg of complete feed.
Example 4
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pig is prepared from the following raw materials in parts by weight: 10g of compound probiotics, 3g of cecropin antibacterial peptide, 5g of plant essential oil, 6g of compound enzyme preparation, 50g of compound acidifier, 4g of organic iron, 4g of organic copper, 4g of nano zinc oxide, 6g of chitosan oligosaccharide, 33 g of vitamin D, 6g of vitamin C, 20g of glutamine, 4g of antioxidant and 120g of crushed corn flour.
The compound enzyme preparation is prepared by mixing β -xylanase 1.5g, β -glucanase 1g, protease 1g, α -amylase 1.5g and phytase 1 g.
The compound acidulant is prepared by mixing 10g of lactic acid, 10g of phosphoric acid, 10g of citric acid, 10g of malic acid and 10g of tartaric acid.
The composite probiotics is prepared by mixing 4g of clostridium butyricum, 4g of bacillus coagulans and 3g of bacillus licheniformis.
The antioxidant is ethoxyquinoline;
the organic iron is the mixture of porphyrin iron and glycine iron;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 2g of oregano oil, 1g of thyme oil and 2g of cinnamon oil.
When in use, 30g of weaned pig nutritional premix is added into 1kg of complete feed.
Example 5
The weaned pig nutritional premix for replacing antibiotics to reduce the diarrhea of the weaned pig is prepared from the following raw materials in parts by weight: 8g of compound probiotics, 4g of cecropin antimicrobial peptide, 3g of plant essential oil, 5g of compound enzyme preparation, 40g of compound acidifier, 3g of organic iron, 2g of organic copper, 3g of nano zinc oxide, 4g of chitosan oligosaccharide, vitamin D32 g, 4g of vitamin C, 10g of glutamine, 3g of antioxidant and 80g of crushed corn flour.
The compound enzyme preparation is prepared by mixing β -xylanase 1g, β -glucanase 1g, protease 1g, α -amylase 1g and phytase 1 g.
The compound acidulant is prepared by mixing 8g of lactic acid, 8g of phosphoric acid, 8g of citric acid, 8g of malic acid and 8g of tartaric acid.
The composite probiotics is prepared by mixing 3g of clostridium butyricum, 3g of bacillus coagulans and 2g of bacillus licheniformis.
The antioxidant is ethoxyquinoline;
the organic iron is glycine iron;
the organic copper is copper methionine.
The plant essential oil is prepared by mixing 1g of oregano oil, 1g of thyme oil and 1g of cinnamon oil.
When in use, 40g of weaned pig nutritional premix is added into 1kg of complete feed.
Experiment on influence of weaned piglet diarrhea
Materials and methods
1.1 test materials
The weaned pig nutritional premix provided by the embodiment 4 of the invention.
1.2 test animals
Weaned piglets are selected from a large pig farm in three areas of Guangxi Nanning, Guangdong Kaiping and Henan Lowe, and are randomly divided into a control group and a test group.
1.3 test methods
The control group was fed with regular daily ration plus antibiotics, the experimental group was fed with regular daily ration plus the nutritional premix for weaned piglets of example 4, and the piglets were fed for 10 days after weaning.
2 results and analysis
2.1 the results of the effect of the invention on diarrhea in weaned piglets are shown in Table 1.
TABLE 1 Effect of the invention on diarrhea in weaned piglets
As can be seen from Table 1, the effect of replacing antibiotics can be completely achieved by adding the nutritional premix for the weaned piglets, the growth performance index of the experimental group piglets exceeds that of the control group piglets, and the diarrhea rate index is also obviously lower than that of the control group piglets. Test results show that the nutritional premix for the weaned pigs provided by the invention can replace antibiotics to reduce the diarrhea rate of the weaned pigs and improve various growth indexes of the weaned pigs.
Although the invention has been described in detail hereinabove by way of general description, specific embodiments and experiments, it will be apparent to those skilled in the art that many modifications and improvements can be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.