CN106110283A - A kind of beauty face-whitening-nourishing compound preparation and preparation method thereof - Google Patents

A kind of beauty face-whitening-nourishing compound preparation and preparation method thereof Download PDF

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CN106110283A
CN106110283A CN201610758160.1A CN201610758160A CN106110283A CN 106110283 A CN106110283 A CN 106110283A CN 201610758160 A CN201610758160 A CN 201610758160A CN 106110283 A CN106110283 A CN 106110283A
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whitening
compound preparation
beauty face
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nourishing
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张志强
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Hangzhou Taihe Health Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/63Arthropods
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    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

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Abstract

The invention discloses a kind of beauty face-whitening-nourishing compound preparation and preparation method thereof, this beauty face-whitening-nourishing compound preparation, is prepared from by following parts by weight meter component: Rhizoma Polygonati Odorati 39 parts, Rhizoma Polygonati 2 12 parts, Fructus Lycii 16 parts, Radix Ginseng 35 parts, the Radix Angelicae Dahuricae 4.5 12.5 parts, 28 parts of Poria, Flos Rosae Rugosae 29 parts, Fructus Jujubae 0.5 4 parts, Rhizoma Zingiberis 0.1 4 parts, 29 parts of Colla Corii Asini, Apis 14 parts.The beauty face-whitening-nourishing compound preparation of the present invention has the effect of beauty face-whitening-nourishing, and safe and reliable, and effect is notable, without any side effects.

Description

A kind of beauty face-whitening-nourishing compound preparation and preparation method thereof
Technical field
The present invention relates to Chinese medicine health-care field, more particularly, it relates to a kind of beauty face-whitening-nourishing compound preparation and preparation side thereof Method.
Background technology
Along with the raising of modern life level, people increasingly focus on external image, with fine image in various work Dynamic self-confident with increase under occasion, simultaneously under fine appearance, more pursue skin health, with healthy skin and fine shape As representing people's pursuit to high-end life.Therefore, whitening class cosmetics are always what people were pursued, and its market share is very Greatly.Whitening class cosmetics are peeled off from the covering whitening of physical property to physical property and chemical, then to disturbing and just blocking melanin Normal metabolism, develops into " cooperative effect " whitening.Whitening product has developed since coming out always, but above-mentioned whitening approach Bring skin damage in various degree to consumer, make skin aging accelerate, even destroy the original defense function of skin, Make skin more sensitive and vulnerable.
Summary of the invention
The technical problem to be solved in the present invention is, for the drawbacks described above of prior art, it is provided that a kind of beauty face-whitening-nourishing is multiple Square preparation and preparation method thereof, this beauty face-whitening-nourishing compound preparation uses natural, the plant extract of nonhazardous effect or Chinese herbal medicine Extract, by rational proportioning, uses strengthening vital QI to eliminate pathogenic factors, keeps fit the Therapeutic Principle that consolidates, by the activity of suppression tyrosine or Block tyrosine and generate melanic oxidative pathway, thus reduce melanic generation, reach the effect of skin whitening.
The technical solution adopted for the present invention to solve the technical problems is: provide a kind of beauty face-whitening-nourishing compound preparation, by such as Lower parts by weight meter component is prepared from:
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, is prepared from by following parts by weight meter component:
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, is prepared from by following parts by weight meter component:
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, described Rhizoma Polygonati Odorati is fragrant solomonseal rhizome polyoses extract, and described Rhizoma Polygonati is Polygonatum polysaccharide extract;Described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini are crushed to micropowder.
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, described fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, the usage ratio of the Radix Angelicae Dahuricae are 1:1.5:1:(1.5-2.5).
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, described fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, usage ratio 1:1.5:1:2.3 of the Radix Angelicae Dahuricae.
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, the fragrant solomonseal rhizome polyoses content of described fragrant solomonseal rhizome polyoses extract is 30%, purchased from Shaanxi Si Nuote Bioisystech Co., Ltd.
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, the polygonatum polysaccharide content of described polygonatum polysaccharide extract is 50%, purchased from Shaanxi Hui Ke plant development corporation, Ltd..
Beauty face-whitening-nourishing compound preparation of the present invention, wherein, described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, red Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini mean diameter all more than 300 mesh.
The present invention also provides for the preparation method of a kind of beauty face-whitening-nourishing compound preparation as above, comprises the steps:
(1) each component is weighed by formula ratio;
(2) by after Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini drying, it is crushed to respectively surpass Fine powder, then mix homogeneously, powder average particle size all, more than 300 mesh, obtains mixed powder;
(3) by fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract stirring container, the mixed of appropriate amount of purified water and Mel is added Close solution, the most at the uniform velocity stir with stirring paddle, become oar material after stirring 40-45min, in slurry, repeatedly add mixed powder on a small quantity Body, continues stirring, until mix homogeneously.
Implement beauty face-whitening-nourishing compound preparation of the present invention and preparation method thereof, have the advantages that
(1) the beauty face-whitening-nourishing compound preparation of the present invention has the effect of beauty face-whitening-nourishing, and safe and reliable, and effect is notable, nothing Any side effect.In the beauty face-whitening-nourishing compound preparation of the present invention, Rhizoma Polygonati Odorati takes effect of its strengthening the body resistance, strengthening by means of tonics, and Rhizoma Polygonati takes Its spleen invigorating, the kidney invigorating, effect of promoting the production of body fluid;Radix Ginseng takes it and grows invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves, and above-mentioned each medicine is made For monarch drug, multiple medicines share, and has strengthening the body resistance, mends effect of each internal organs vital essence deficiency.And Fructus Lycii takes its hard muscles and bones, mends vital essence Effect of various symptoms and signs of deficiency, Fructus Jujubae takes its invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid, and Colla Corii Asini takes effect of its YIN nourishing of enriching blood;Three medicines share, as minister Medicine, has effect of the strengthening the body resistance of further assistant reinforcement monarch drug.And Poria takes effect of its eliminating dampness and diuresis, the Radix Angelicae Dahuricae takes it and dissipates Effect of wind dehumidifying, excessive moisture in removing body;Flos Rosae Rugosae takes effect of dispersing the stagnated live-QI to relieve the stagnation of QI, the catharsis of conditioning liver;Rhizoma Zingiberis takes it The merit that warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation;Multiple medicines share, and has eliminating dampness and diuresis, effect that dispersing the stagnated live-QI to relieve the stagnation of QI, recuperating depleted YANG are promoted blood circulation, as adjuvant drug, Assist conditioning because of the weakened body resistance various symptoms caused.Mel as harmonizing drug, for being in harmonious proportion the property of medicine of each medicine, makes this formula more heat With, effectively;
(2) it should be noted that and the study find that, when fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, the Radix Angelicae Dahuricae Usage ratio be 1:1.5:1:(1.5-2.5), whitening effect is had obvious curative effect, as more preferably scheme, an institute State fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, usage ratio 1:1.5:1:2.3 of the Radix Angelicae Dahuricae, whitening effect is had Significant curative effect.Its lightening mechanism may be by suppressing the activity of tyrosine or block tyrosine to generate melanic oxidation way Footpath, thus reduce melanic generation, reach the effect of skin whitening.It addition, lot of experiments research finds, remove fragrant solomonseal rhizome polyoses Extract, polygonatum polysaccharide extract, its whitening effect also can have a greatly reduced quality, and therefore fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract Thing and Radix Ginseng, the Radix Angelicae Dahuricae with the use of, there is the merit of Synergistic;
(3) fragrant solomonseal rhizome polyoses extract and polygonatum polysaccharide extract replace crude drug powder, it is possible to reduce consumption of taking medicine, with people Ginseng, Radix Angelicae Dahuricae use in conjunction, have the effect of Synergistic, skin whitening had remarkable result.But, the extraction of these medical materials Thing has certain hygroscopicity, and easy moisture absorption is made moist, and causes going bad, and in the formula of the present invention, uses Fructus Lycii, Radix Ginseng, white The micropowder that the root of Dahurian angelica, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis micropowder process adds to mixed extract, it is possible to absorption mixed extract Moisture, make preparation be dried, be unlikely to deteriorate;
(4) it addition, because with the addition of Fructus Lycii superfine powder, Flos Rosae Rugosae superfine powder and Fructus Jujubae superfine powder, the delicate fragrance that both are intrinsic With micro-sweet taste, it is not necessary to the most deliberately add sweeting agent or correctives, save production cost and production process;
(5) Fructus Lycii of the present invention, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini use ultrastructurepower technology Fully absorbing of more favourable Chinese medicine, and then shorten the drug use course for the treatment of and reduce dosage, improve curative effect of medication, reduce The risk that medicine drug residue etc. in food animal brings.
Detailed description of the invention
Below, in conjunction with detailed description of the invention, the present invention is described further:
In the present invention, if not refering in particular to, all of part, percentage ratio are unit of weight, the equipment used and raw material etc. All it is commercially available or commonly used in the art.Method in following embodiment, if no special instructions, is the normal of this area Rule method.
The present invention provides a kind of beauty face-whitening-nourishing compound preparation, following parts by weight meter component be prepared from:
Preferably, this beauty face-whitening-nourishing compound preparation is prepared from by following parts by weight meter component: Rhizoma Polygonati Odorati 3.5-6.5 part, Rhizoma Polygonati 2-8 part, Fructus Lycii 5-6 part, Radix Ginseng 4-5 part, Radix Angelicae Dahuricae 6-12.5 part, Poria 3-5 part, Flos Rosae Rugosae 3-6 part, Fructus Jujubae 1-3 part, Rhizoma Zingiberis 0.5-2 part, Colla Corii Asini 4-5 part, Apis 2-3 part.
As scheme most preferably, this beauty face-whitening-nourishing compound preparation is prepared from by following parts by weight meter component: beautiful 4 parts of bamboo, Rhizoma Polygonati 6 parts, Fructus Lycii 5.2 parts, Radix Ginseng 4 parts, 9.2 parts of Poria, the Radix Angelicae Dahuricae 4.8 parts, Flos Rosae Rugosae 3.8 parts, Fructus Jujubae 2 parts, dry Rhizoma Zingiberis Recens 1.6 parts, 4.5 parts of Colla Corii Asini, Apis 2.5 parts.
Rhizoma Polygonati Odorati: sweet in the mouth, is slightly cold.There is effect of strengthening the body resistance, nourishing YIN to relieve dryness and strengthening by means of tonics.Hinder for lung stomach-Yin, dry Heat cough, dry throat and mouth, interior-heat is quenched one's thirst.Modern pharmacological research shows, immunologic function is also had certain regulation to make by fragrant solomonseal rhizome polyoses With, it may have antioxidation, the effect of defying age.
Rhizoma Polygonati: sweet in the mouth, property are flat, return spleen, lung, kidney channel, has spleen invigorating, the kidney invigorating, lung moistening, the function such as promote the production of body fluid." angle's Ganoderma lucidum seu Japonicum Warp " say its " alleviating distention in middle-JIAO QI invigorating, makes the five internal organs adjust good, muscle sufficiency, the not oldest, and color clear is turned white more black, and dedentition is more raw ", say Bright Rhizoma Polygonati has life lengthening, preserves the effect of intensive culture face.Pharmacological research finds, Rhizoma Polygonati has antioxidation, defying age, blood sugar lowering, fall Blood fat, improve and improve the effect such as memory, antitumor, regulation immunity, antiviral, antiinflammatory.
Fructus Lycii: be the traditional tonic Chinese medicine material of China.Fructus Lycii described in Compendium of Material Medica has hard muscles and bones, mends vital essence Various symptoms and signs of deficiency, improving eyesight calm the nerves, makes us the effect such as long-lived.People have carried out wide research to Lycium barbarum polysaccharides at present, find Chinese holly Qi polysaccharide has enhancing human body immunity power, antitumor, defying age, blood fat reducing, blood sugar lowering, resisting fatigue, hepatoprotective, radioprotective, anti-lacks The effects such as oxygen.
Radix Ginseng: sweet in the mouth, hardship warm in nature, micro-, Radix Ginseng has and multiple disease is had preventive effect, to human body grow invigorating the spleen to benefit the lung, Promoting the production of body fluid to quench thirst, Fructus Alpiniae Oxyphyllae of calming the nerves, tune Rong Yangwei, strongly invigorating primordial QI, multiple arteries and veins take off admittedly, be classified as top grade, be conventional in Shennong's Herbal Strengthening by means of tonics medicine.Radix Ginseng energy enhancing body autoimmune function.Ginsenoside's phagocytosis merit to the endothelial system of intact animal Can there be stimulation and facilitation, autoimmune can be made to strengthen, be also immunomodulator.
The Radix Angelicae Dahuricae: it is warm in nature, gas fragrance, acrid in the mouth, micro-hardship, return stomach, colon, lung meridian, there is the dehumidifying of scattered wind, sensible analgesia, disappear The effects such as swollen evacuation of pus.Clinic is mainly used in treating headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea and skin infection and swells and ache Deng card.The study find that, the Radix Angelicae Dahuricae, Radix Ginseng use in conjunction synergistic function in terms of antioxidation and whitening.
Poria: for conventional damp-clearing drug, property hides: sweet in the mouth, light;Property flat;GUIXIN, lung, spleen, kidney channel;Poria has eliminating dampness by diuresis The effects such as diuretic, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, for oral administration can treat insufficiency of the spleen, dysuria, edema distension, cough with copious phlegm, have loose bowels, Seminal emission, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful, external application recorded by ancient book can also treat black speck on the face.Poria main component has Poria many Sugar, su-fuling etc..Modern pharmacology research Poria have diuresis, immunomodulating, protect the liver, antitumor, antioxidation, antiinflammatory, disease-resistant The multiple pharmacological effect such as poison.
Flos Rosae Rugosae: Flos Rosae Rugosae is long as QI regulating medicine applicating history in motherland's medicine and pharmacology, has resolving depression of regulating the flow of vital energy, Huoxue San " The effect become silted up, distending pain of the breast, stomachache due to hyperactive liver-QI attacking the stomach etc. vexed for the fullness in the chest and hypochondrium caused by depression of liver-QI.Modern pharmacological research shows, Flos Rosae Rugosae The pharmacological action of flower is extensive, especially in cardiovascular disease, treatment and antitumor, antioxidation and function of gallbladder promoting, the solution of immune inflammation The aspects such as poison have effect so that this Chinese medicine is more widely used clinically.
Fructus Jujubae: sweet, warm in nature, energy invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid, it is used for treating " insufficiency of the spleen weak, anorexia and loose stool, deficiency of qi and blood " etc. Disease.Often food Fructus Jujubae can treat physical weakness, neurasthenia, incoordination between the spleen and stomach, dyspepsia, epersalgia cough, anemia are become thin, nourishing the liver Preventing cancer function is especially prominent, has saying of " three Fructus Jujubaes of solar eclipse, at the age of one hundred years old bear one's age well ".It is characterized in that vitamin content is the highest, have " my god So vitamin pill " good reputation, there is nourishing YIN and invigorating YANG, the effect enriched blood.
Rhizoma Zingiberis: acrid in the mouth, property heat;Return spleen, stomach, kidney, the heart, lung meridian;Having warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the merit of warming the lung to resolve fluid-retention Effect, for coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, and cold fluid-retention is breathed with cough.
Colla Corii Asini: be dried skin or Cortex Dictamni through decocting, concentrating the solid gum made for equine species donkey.Sweet in the mouth, property are flat, return lung, Liver, kidney channel.Have YIN nourishing of enriching blood, moisturize, effect of hemostasis, be respectfully called enrich blood " panacea " by ancient Chinese medicine doctor.Cure mainly blood deficiency and yellow complexion, Dizziness cardiopalmus, flesh flaccidity is unable, dysphoria and insomnia, stirring-up of pathogenic wind in the interior resulting from deficiency, xeropulmonary cough, and consumptive disease coughs spitting of blood, haematemesis hematuria, metrorrhagia of having blood in stool, gestation Vaginal bleeding during pregnancy.
Mel: what Mel was well recognized as has the wholefood of various biological activity, is medically being used widely.With And Mel research deepened continuously, find Mel exists substantial amounts of phenolic compound, phenolic material mass-energy remove OH be by Provide the hydrogen on phenolic hydroxyl group in phenolic compound, and make OH reduce.Additionally, aldehydes matter can also be by metal ion Complexation, reduces the speed of Fenton reaction, thus indirectly realizes antioxidation.Can also effectively reduce melanin deposition, make Skin more water moistens, and prevents scaly dry skin, makes skin the most pale soft, additionally it is possible to effectively helps pre-anti-acne, smoothes away wrinkles.
The traditional Chinese medical science is thought, it is diversified for causing the pathogenetic reason of skin, such as six climate exopathogens, seven emotions, diet, work and rest, insect poison And wound etc., the raw dermatosis of Crinis Carbonisatus can be made under certain condition.From Overall View, the cause of disease is caused a disease and is related to two aspects: One be the resistance against diseases of human body own relatively to weaken, so-called " weakened body resistance ";Two is that paathogenic factor is relatively imitative contains, so-called " domination of pathogen ".One For as, the often directly contamination skin such as six climate exopathogens, insect poison and fall ill, seven emotions, diet etc. can cause skin after affecting function indirectly Skin is sick.
In the beauty face-whitening-nourishing compound preparation of the present invention, Rhizoma Polygonati Odorati takes effect of its strengthening the body resistance, strengthening by means of tonics, and Rhizoma Polygonati takes it and is good for Spleen, the kidney invigorating, effect of promoting the production of body fluid;Radix Ginseng takes it and grows invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves, and above-mentioned each medicine is as monarch Medicine, multiple medicines share, and has strengthening the body resistance, mends effect of each internal organs vital essence deficiency.And Fructus Lycii takes its hard muscles and bones, to mend vital essence all not Effect of foot, Fructus Jujubae takes its invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid, and Colla Corii Asini takes effect of its YIN nourishing of enriching blood;Three medicines share, as ministerial drug, There is effect of the strengthening the body resistance of further assistant reinforcement monarch drug.And Poria takes effect of its eliminating dampness and diuresis, the Radix Angelicae Dahuricae takes its scattered wind Effect of dehumidifying, excessive moisture in removing body;Flos Rosae Rugosae takes effect of dispersing the stagnated live-QI to relieve the stagnation of QI, the catharsis of conditioning liver;Rhizoma Zingiberis takes its temperature The merit that middle cold expelling, recuperating depleted YANG are promoted blood circulation;Multiple medicines share, and has eliminating dampness and diuresis, effect that dispersing the stagnated live-QI to relieve the stagnation of QI, recuperating depleted YANG are promoted blood circulation, as adjuvant drug, association Help conditioning because of the weakened body resistance various symptoms caused.Mel as harmonizing drug, for being in harmonious proportion the property of medicine of each medicine, makes this formula more heat With, effectively.
It should be noted that and the study find that, when fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, the use of the Radix Angelicae Dahuricae Amount ratio is 1:1.5:1:(1.5-2.5), whitening effect is had obvious curative effect, as more preferably scheme, a described jade Bamboo polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, usage ratio 1:1.5:1:2.3 of the Radix Angelicae Dahuricae, have significantly whitening effect Curative effect.Its lightening mechanism may be by suppressing the activity of tyrosine or block tyrosine to generate melanic oxidative pathway, from And reduce melanic generation, reach the effect of skin whitening.It addition, lot of experiments research finds, remove fragrant solomonseal rhizome polyoses and extract Thing, polygonatum polysaccharide extract, its whitening effect also can have a greatly reduced quality, therefore fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract with Radix Ginseng, the Radix Angelicae Dahuricae with the use of, there is the merit of Synergistic.
As the preferred version of the present invention, described Rhizoma Polygonati Odorati is fragrant solomonseal rhizome polyoses extract, and described Rhizoma Polygonati is that polygonatum polysaccharide extracts Thing;Described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini are crushed to micropowder.
The fragrant solomonseal rhizome polyoses content of described fragrant solomonseal rhizome polyoses extract is 30%, purchased from the Shaanxi limited public affairs of Si Nuote biotechnology Department.Or use following methods to prepare: Rhizoma Polygonati Odorati is cleaned, chopping, through 65% alcohol reflux defat, it is subsequently adding water extraction, concentrates, Precipitate with ethanol, removing protein, centrifugal, vacuum drying, obtain fragrant solomonseal rhizome polyoses.
The polygonatum polysaccharide content of described polygonatum polysaccharide extract is 50%, purchased from Shaanxi Hui Ke plant development corporation, Ltd.. Or adopt and prepare with the following method: Rhizoma Polygonati is cleaned, chopping, add soak by water three times, filter, merge the filtrate of three times;Filtrate is adopted With NKA-9 macroporous adsorbent resin polygonatum polysaccharide it is purified and get final product;Macroporous adsorbent resin technique is 20g NKA-9 resin wet method Dress post, loading filter liquor concentration about 3.90mg/ml, loading flow velocity 2ml/min, stand eluting after 12h, with the ethanol solution of 30% 120ml is as eluant, elution speed 2ml/min.
Fragrant solomonseal rhizome polyoses extract and polygonatum polysaccharide extract replace crude drug powder, it is possible to reduce consumption of taking medicine, with Radix Ginseng, Radix Angelicae Dahuricae use in conjunction, has the effect of Synergistic, skin whitening is had remarkable result.But, the extract of these medical materials Having certain hygroscopicity, easy moisture absorption is made moist, and causes going bad, and in the formula of the present invention, use Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, The micropowder that Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis micropowder process adds to mixed extract, it is possible to absorption mixed extract Moisture, makes preparation be dried, is unlikely to deteriorate.It addition, because with the addition of Fructus Lycii superfine powder, Flos Rosae Rugosae superfine powder and Fructus Jujubae superfine powder, Both intrinsic delicate fragrance and micro-sweet taste, it is not necessary to the most deliberately add sweeting agent or correctives, save production cost and production process.
As the preferred version of the present invention, described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini Mean diameter all more than 300 mesh.The Fructus Lycii of the present invention, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini make With fully absorbing of the more favourable Chinese medicine of ultrastructurepower technology, and then shorten the drug use course for the treatment of and reduce dosage, improve Curative effect of medication, decreases the risk that medicine drug residue etc. in food animal brings.
The beauty face-whitening-nourishing compound preparation of the present invention can be prepared as any oral preparations by the common process of pharmaceutics.
Embodiment 1A kind of beauty face-whitening-nourishing compound preparation
It is prepared from by the component of following parts by weight:
Fragrant solomonseal rhizome polyoses extract 4 parts, polygonatum polysaccharide extract 6 parts, Fructus Lycii 5.2 parts, Radix Ginseng 4 parts, 9.2 parts of Poria, white The root of Dahurian angelica 4.8 parts, Flos Rosae Rugosae 3.8 parts, Fructus Jujubae 2 parts, Rhizoma Zingiberis 1.6 parts, 4.5 parts of Colla Corii Asini, Apis 2.5 parts.
Preparation method, comprises the steps:
(1) each component is weighed by formula ratio;
(2) by after Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini drying, it is crushed to respectively surpass Fine powder, then mix homogeneously, powder average particle size all, more than 300 mesh, obtains mixed powder;
(3) by fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract stirring container, the mixed of appropriate amount of purified water and Mel is added Close solution, the most at the uniform velocity stir with stirring paddle, become oar material after stirring 40-45min, in slurry, repeatedly add mixed powder on a small quantity Body, continues stirring, until mix homogeneously.
Wherein, the fragrant solomonseal rhizome polyoses content of described fragrant solomonseal rhizome polyoses extract is 30%, has purchased from Shaanxi Si Nuote biotechnology Limit company.The polygonatum polysaccharide content of described polygonatum polysaccharide extract is 50%, purchased from Shaanxi Hui Ke plant development corporation, Ltd..
Embodiment 2-8A kind of beauty face-whitening-nourishing compound preparation
Proportioning according to the form below 1 weighs raw material respectively, is prepared according to the step in embodiment 1, and difference is The proportioning raw materials added is different, prepares product, specifically refers to table 1:
Table 1: embodiment 2-8 proportioning raw materials table
Comparative example 1A kind of beauty face-whitening-nourishing compound preparation
It is prepared from by the component of following parts by weight:
Rhizoma Polygonati Odorati 4 parts, Rhizoma Polygonati 6 parts, Fructus Lycii 5.2 parts, Radix Ginseng 4 parts, 9.2 parts of Poria, the Radix Angelicae Dahuricae 4.8 parts, Flos Rosae Rugosae 3.8 parts, Fructus Jujubae 2 parts, Rhizoma Zingiberis 1.6 parts, 4.5 parts of Colla Corii Asini, Apis 2.5 parts.
Preparation method, comprises the steps:
(1) each component is weighed by formula ratio;
(2) by after Rhizoma Polygonati Odorati, Rhizoma Polygonati, Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini drying, divide Not being crushed to micropowder, then mix homogeneously, powder average particle size all, more than 300 mesh, obtains mixed powder;
(3) by adding appropriate amount of purified water and the mixed solution of Mel, the most at the uniform velocity stir with stirring paddle, stir 40-45min Rear one-tenth oar material, repeatedly adds mixed powder in slurry on a small quantity, continues stirring, until mix homogeneously.
Comparative example 2A kind of beauty face-whitening-nourishing compound preparation
It is prepared from by the component of following parts by weight:
Fructus Lycii 5.2 parts, Radix Ginseng 4 parts, 9.2 parts of Poria, the Radix Angelicae Dahuricae 4.8 parts, Flos Rosae Rugosae 3.8 parts, Fructus Jujubae 2 parts, Rhizoma Zingiberis 1.6 Part, 4.5 parts of Colla Corii Asini, Apis 2.5 parts.
Preparation method, comprises the steps:
(1) each component is weighed by formula ratio;
(2) by after Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini drying, it is crushed to respectively surpass Fine powder, then mix homogeneously, powder average particle size all, more than 300 mesh, obtains mixed powder;
(3) by adding appropriate amount of purified water and the mixed solution of Mel, the most at the uniform velocity stir with stirring paddle, stir 40-45min Rear one-tenth oar material, repeatedly adds mixed powder in slurry on a small quantity, continues stirring, until mix homogeneously.
Below, the beauty face-whitening-nourishing compound preparation that Example 1-8 and comparative example 1-2 prepares, skin-whitening is imitated Fruit detects, and the results are shown in Table 2.
The beauty face-whitening-nourishing compound preparation that embodiment 1-8 and the comparative example 1-2 of preparation prepare is respectively issued to 100 Tester tests use, and tester takes beauty face-whitening-nourishing compound preparation and takes in the same manner, and every day takes, and takes continuously With one month.Often group embodiment has 10 testers to take, and beauty face-whitening-nourishing compound preparation is entered by tester according to the sensation of oneself Row scoring, scoring uses ten point system, and 1 is divided into worst, and 5 points moderate, and 10 are divided into best, and the highest effect of score is the best, using effect Evaluation result such as table 2.
Table 2 embodiment 1-8 and the test result of comparative example 1-2
Whitening degree Mottle desalination degree
Comparative example 1 6.2 6.7
Comparative example 2 4.8 5
Embodiment 1 9.6 8.5
Embodiment 2 6.4 6.1
Embodiment 3 7.2 7.3
Embodiment 4 7.5 7.6
Embodiment 5 7.9 7.0
Embodiment 6 6.6 7.4
Embodiment 7 7.5 6.8
Embodiment 8 7.1 6.2
By data in upper table it can be seen that after tester takes the beauty face-whitening-nourishing compound preparation of embodiment of the present invention 1-8, its Skin-whitening degree and mottle desalination degree all have preferably improvement, are embodied in the glossiness increasing skin, and skin is fine and smooth Mellow and full, and do not have an example tester that the phenomenons such as allergy, skin discomfort occur.Especially, the formula proportion of embodiment 1, its colour of skin Whitening degree and mottle desalination degree best results, average is all more than 8.Visible, its beauty face-whitening-nourishing of the formula of the present invention Effect is mainly by strengthening the body resistance, the evil positive deficiency and excess of conditioning own bodies, and combines modern pharmacological research, each by rational allocation The usage ratio of medicine, especially fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract, Radix Ginseng, the ratio of the Radix Angelicae Dahuricae, make this formula have Excellent beauty face-whitening-nourishing effect.
It should be noted that with the formula variation of embodiment 1, comparative example 1 is that Rhizoma Polygonati Odorati and Rhizoma Polygonati use powder Being used as medicine, rather than extract is used as medicine, the consumption of two Example formulations is identical, but from the point of view of effect, uses powder to be used as medicine, its skin Skin whitening degree and mottle desalination degree effect decrease.
Comparative example 2 is to remove fragrant solomonseal rhizome polyoses extract and polygonatum polysaccharide extract with the formula variation of embodiment 1, Its skin-whitening degree and mottle desalination degree effect are had a greatly reduced quality.
It will be apparent to those skilled in the art that can technical scheme as described above and design, make other various Corresponding change and deformation, and all these change and deformation all should belong to the protection domain of the claims in the present invention Within.

Claims (10)

1. a beauty face-whitening-nourishing compound preparation, it is characterised in that be prepared from by following parts by weight meter component:
Beauty face-whitening-nourishing compound preparation the most according to claim 1, it is characterised in that prepared by following parts by weight meter component Form:
Beauty face-whitening-nourishing compound preparation the most according to claim 1, it is characterised in that prepared by following parts by weight meter component Form:
4. according to the beauty face-whitening-nourishing compound preparation described in any one of claim 1-3, it is characterised in that described Rhizoma Polygonati Odorati is that Rhizoma Polygonati Odorati is many Sugar extract, described Rhizoma Polygonati is polygonatum polysaccharide extract;Described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini is crushed to micropowder.
Beauty face-whitening-nourishing compound preparation the most according to claim 4, it is characterised in that described fragrant solomonseal rhizome polyoses extract, Rhizoma Polygonati Polyoses extract, Radix Ginseng, the usage ratio of the Radix Angelicae Dahuricae are 1:1.5:1:(1.5-2.5).
Beauty face-whitening-nourishing compound preparation the most according to claim 4, it is characterised in that described fragrant solomonseal rhizome polyoses extract, Rhizoma Polygonati Polyoses extract, Radix Ginseng, usage ratio 1:1.5:1:2.3 of the Radix Angelicae Dahuricae.
Beauty face-whitening-nourishing compound preparation the most according to claim 4, it is characterised in that the Rhizoma Polygonati Odorati of described fragrant solomonseal rhizome polyoses extract Polyoses content is 30%, purchased from Shaanxi Si Nuote Bioisystech Co., Ltd.
Beauty face-whitening-nourishing compound preparation the most according to claim 4, it is characterised in that the Rhizoma Polygonati of described polygonatum polysaccharide extract Polyoses content is 50%, purchased from Shaanxi Hui Ke plant development corporation, Ltd..
Beauty face-whitening-nourishing compound preparation the most according to claim 4, it is characterised in that described Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Fu Siberian cocklebur, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini mean diameter all more than 300 mesh.
10. the preparation method of a beauty face-whitening-nourishing compound preparation as claimed in claim 4, it is characterised in that include walking as follows Rapid:
(1) each component is weighed by formula ratio;
(2) by after Fructus Lycii, Radix Ginseng, the Radix Angelicae Dahuricae, Poria, Flos Rosae Rugosae, Fructus Jujubae, Rhizoma Zingiberis, Colla Corii Asini drying, it is crushed to ultra-fine respectively Powder, then mix homogeneously, powder average particle size all, more than 300 mesh, obtains mixed powder;
(3) by fragrant solomonseal rhizome polyoses extract, polygonatum polysaccharide extract stirring container, the mixing adding appropriate amount of purified water and Mel is molten Liquid, the most at the uniform velocity stirs with stirring paddle, becomes oar material, repeatedly add mixed powder on a small quantity, continue in slurry after stirring 40-45min Continuous stirring, until mix homogeneously.
CN201610758160.1A 2016-08-29 2016-08-29 A kind of beauty face-whitening-nourishing compound preparation and preparation method thereof Withdrawn CN106110283A (en)

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Application publication date: 20161116