CN1053364A - Preparation method of xanthium sibiricum volatile oil preparation - Google Patents
Preparation method of xanthium sibiricum volatile oil preparation Download PDFInfo
- Publication number
- CN1053364A CN1053364A CN 91101133 CN91101133A CN1053364A CN 1053364 A CN1053364 A CN 1053364A CN 91101133 CN91101133 CN 91101133 CN 91101133 A CN91101133 A CN 91101133A CN 1053364 A CN1053364 A CN 1053364A
- Authority
- CN
- China
- Prior art keywords
- volatile oil
- preparation
- herba xanthii
- xanthium sibiricum
- sodium chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000341 volatile oil Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 241001251949 Xanthium sibiricum Species 0.000 title claims abstract description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 14
- 239000011780 sodium chloride Substances 0.000 claims abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 4
- 238000000605 extraction Methods 0.000 claims abstract description 4
- 244000025254 Cannabis sativa Species 0.000 claims description 9
- 230000000172 allergic effect Effects 0.000 claims description 7
- 208000010668 atopic eczema Diseases 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 238000002347 injection Methods 0.000 claims description 4
- 206010039083 rhinitis Diseases 0.000 claims description 4
- 239000011550 stock solution Substances 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 3
- 239000002674 ointment Substances 0.000 claims description 3
- 239000003380 propellant Substances 0.000 claims description 3
- 238000007689 inspection Methods 0.000 claims description 2
- 239000003883 ointment base Substances 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 2
- 229920000053 polysorbate 80 Polymers 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 6
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 2
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 description 3
- 230000007815 allergy Effects 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a method for extracting volatile oil from xanthium sibiricum and preparing a preparation for clinical application. The extraction method of the xanthium sibiricum volatile oil is to cut the fresh xanthium sibiricum, add sodium chloride, extract the volatile oil by a volatile oil extraction device, and add auxiliary materials according to the clinical medication requirement and the characteristics of different formulations to prepare various pharmaceutical preparations for treating allergic reactions.
Description
The invention relates to a kind of method of extracting volatile oil and make preparation from Chinese herbal medicine, more particularly extract volatile oil from Herba Xanthii grass, and be made into the method for preparation, international Patent classificating number is A61K35/00.
In the prior art, be used for the treatment of allergic injection, medicament and topical drug are a lot, but generally they are made by Western medicine.The most conventional, the allergic medicament of treatment commonly used is Piao Ermin, although it is that effectively the course of treatment is oversize.Chinese medicine preparation is used to control allergicly also to be had, but different with the present invention.Up to now, the applicant does not see and publishes on the domestic and international various publication or report with Herba Xanthii grass and control allergic article, message.
One of purpose of the present invention is to make full use of the Herba Xanthii grass that Chinese the earth all has everywhere, through extracting volatile oil, treats allergy with this oil.
Two of purpose of the present invention is to make injection with Herba Xanthii volatile oil.
Three of purpose of the present invention is to make the aerosol that the treatment rhinitis is used with Herba Xanthii volatile oil.
Four of purpose of the present invention is to make externally-applied ointment with Herba Xanthii volatile oil.
Other purpose of the present invention and task will further be set forth by following description.
It is long at first fresh Herba Xanthii grass to be cut into 0.5-1cm, grow slightly or lack slightly and also can, then with Herba Xanthii grass, sodium chloride is put in the boiler, add entry, extract volatile oil with volatile oil extractor, the ratio of batching is a Herba Xanthii grass: sodium chloride: water=1: 0.01: 5 can certainly be 1: 0.001-0.1: in the 1-10 scope.At this device therefor all is known, and this professional field the technical staff know.Extraction process also is known.
Then with Herba Xanthii volatile oil: water=1: the 500-5000 ratio is made into stock solution, and after filtration, embedding adds propellant and makes the rhinitis aerosol.Use active carbon or microporous filter membrane (0.2um) to filter at this, make propellant with fluorine Lyons 12,14 grades.
With Herba Xanthii volatile oil: sodium chloride: tween 80: the ratio of water=1: 3-10: 1: 500-5000 is mixed with stock solution, after filtration, and embedding, autoclaving, lamp inspection, lettering, packing, make the allergic injection of treatment, in this used step method, equipment is used always.
Herba Xanthii volatile oil is added in the ointment base, and ratio can be arbitrarily, and through even matter, the allergic externally-applied ointment of treatment is made in embedding.Can be paraffin in this substrate, vaseline etc., even matter is used homogenizer or mill.
Volatile oil preparation manufactured goods of the present invention can be treated allergy well, especially treat rhinitis.Can reach more than 90% for treatment allergy effective percentage according to statistics, and the rate height that takes effect, in short-term can be effectively, the patient who is adapted to vast cities and towns uses, and has opened up a new field for the use of China's Chinese herbal medicine, has filled up international and domestic blank.
Claims (4)
1, the preparation method of xanthium sibiricum volatile oil pharmaceutical, it is characterized in that Herba Xanthii volatile oil: water=1: the 500-5000 ratio is made into stock solution, and after filtration, embedding adds propellant, makes the rhinitis aerosol.
2, the preparation method of xanthium sibiricum volatile oil pharmaceutical, it is characterized in that Herba Xanthii volatile oil: sodium chloride: tween 80: the ratio of water=1: 3-10: 1: 500-5000 is mixed with stock solution, after filtration, embedding, autoclaving, lamp inspection, lettering, packing is made the allergic injection of treatment.
3, the preparation method of xanthium sibiricum volatile oil pharmaceutical is characterized in that Herba Xanthii volatile oil is added ointment base, and through even matter, the allergic externally-applied ointment of treatment is made in embedding.
4,, it is characterized in that wherein the extraction of Herba Xanthii volatile oil prepares as follows as the preparation method of the described xanthium sibiricum volatile oil pharmaceutical of claim 1-3:
A, it is long that fresh Herba Xanthii grass is cut into 0.5-1cm;
B puts Herba Xanthii grass, sodium chloride in the boiler, adds entry, extracts volatile oil with volatile oil extractor, and the ratio of batching is a Herba Xanthii grass: sodium chloride: water=1: 0.01: 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91101133 CN1053364A (en) | 1991-03-02 | 1991-03-02 | Preparation method of xanthium sibiricum volatile oil preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91101133 CN1053364A (en) | 1991-03-02 | 1991-03-02 | Preparation method of xanthium sibiricum volatile oil preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1053364A true CN1053364A (en) | 1991-07-31 |
Family
ID=4904970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 91101133 Pending CN1053364A (en) | 1991-03-02 | 1991-03-02 | Preparation method of xanthium sibiricum volatile oil preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1053364A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093397C (en) * | 1999-11-22 | 2002-10-30 | 陈曙 | Traditional Chinese medicinal beautifying cosmetics |
| WO2003013567A1 (en) * | 2001-08-09 | 2003-02-20 | Chinese Herbal Usa, Inc. | Compositions for the treatment of acquired immunodeficiency disease |
| CN102138950A (en) * | 2011-01-27 | 2011-08-03 | 徐州市第一人民医院 | Quality control method for Siberian cocklebur grass |
-
1991
- 1991-03-02 CN CN 91101133 patent/CN1053364A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093397C (en) * | 1999-11-22 | 2002-10-30 | 陈曙 | Traditional Chinese medicinal beautifying cosmetics |
| WO2003013567A1 (en) * | 2001-08-09 | 2003-02-20 | Chinese Herbal Usa, Inc. | Compositions for the treatment of acquired immunodeficiency disease |
| CN102138950A (en) * | 2011-01-27 | 2011-08-03 | 徐州市第一人民医院 | Quality control method for Siberian cocklebur grass |
| CN102138950B (en) * | 2011-01-27 | 2012-07-04 | 徐州市第一人民医院 | Quality control method for Siberian cocklebur grass |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination |