CN104922278B - It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method - Google Patents
It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method Download PDFInfo
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- CN104922278B CN104922278B CN201510387084.3A CN201510387084A CN104922278B CN 104922278 B CN104922278 B CN 104922278B CN 201510387084 A CN201510387084 A CN 201510387084A CN 104922278 B CN104922278 B CN 104922278B
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Abstract
The present invention relates to it is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method.Raw material is desmodium 100g, oriental wormwood 100g, Radix Isatidis 100g, Fructus Aurantii（Fry）67g, radix bupleuri（System）67g, radix scutellariae 100g, cape jasmine 67g, fruit of Chinese magnoliavine 134g；The taste of the above eight, add the water of 5 times of amounts, soak 30~60 minutes, circumfluence distillation 2 hours, 8 hours are stood, filtration, filtrate decompression is condensed into paste, adds ethanol to make to contain determining alcohol up to 50%, 12 hours are stood, filtration, ethanol is recovered under reduced pressure to without alcohol taste, obtains relative density as 1.29~1.32（22oC is surveyed）Thick paste, add dextrin 214g and honey element 9.6g, mix, particle is made, dry, 320g is made, produces.Medicine high income made of the present invention, improves work efficiency, improves yield, the effect of improving product.Using sugar-free auxiliary material, make the patient of diabetes, hyperglycaemia can also take.
Description
Technical field
The present invention relates to a kind of Chinese medicinal preparation method, it is specifically a kind of for liver and gall with the medicine controlled, liver-yang hyperactivity, fire are strongly fragrant
And preparation method.Trade name：With liver choleretic granules（Drug standards numbering WS3-B-1358-93-1）.
Background technology
In prior art, and liver choleretic granules（Drug standards numbering WS3-B-1358-93-1）To treat heat-clearing
Dampness removing, liver-smoothing, qi-regulating.For acute icteric hepatitis, chronic hepatitis of active stage, acute and chronic cholecystitis.Its prescription is：Desmodium
100g, oriental wormwood 100g, Radix Isatidis 100g, Fructus Aurantii（Fry）67g, radix bupleuri（System）67g, radix scutellariae 100g, cape jasmine 67g, fruit of Chinese magnoliavine 134g.
Preparation method is：The taste of the above eight, add water to cook secondary, each each 1 hour, collecting decoction, standing 8 hours, filtration, filtrate decompression
Paste is condensed into, adds ethanol to make to stand 12 hours up to 50% containing determining alcohol, filtration, ethanol is recovered under reduced pressure to without alcohol taste, obtains relatively
Density is 1.29-1.32（22 DEG C of surveys）Thick paste, add dextrin 214g and honey element 9.6g, mix, particle is made, dry, system
Into 320g, produce.The dried cream yield that the technique obtains is 10.8%.The preparation method shortcoming is that the production time is long, and work efficiency is low,
The dried cream yield that it is obtained is low.
The content of the invention
The purpose of the present invention be for above-mentioned deficiency and provide a kind of technological effect preferably it is a kind of be used for liver and gall with control, liver
The strongly fragrant medicine of positive rising, fire and preparation method.
The present invention technical solution be：It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method
Comprise the following steps：
（1）Raw material is desmodium 100g, oriental wormwood 100g, Radix Isatidis 100g, Fructus Aurantii（Fry）67g, radix bupleuri（System）67g, radix scutellariae
100g, cape jasmine 67g, fruit of Chinese magnoliavine 134g.
（2）The taste of the above eight, add the water of 5 times of amounts, soak 30~60 minutes, circumfluence distillation 2 hours, stand 8 hours, filter
Cross.
（3）Filtrate decompression is condensed into paste, adds ethanol to make to stand 12 hours up to 50% containing determining alcohol.
（4）Filtration, ethanol is recovered under reduced pressure to without alcohol taste, obtains relative density as 1.29-1.32（22 DEG C of surveys）Thick paste.
（5）Dextrin 214g and honey element 9.6g is added, mixes, particle is made, dries, 320g is made, produces.
Advantages of the present invention：1st, medicine yield made of the present invention improves work efficiency, improves dry cream than traditional handicraft high income
Yield, active ingredient is not decomposed in preparation process, is had a clear superiority than former method, the effect of improving product.2nd, by
In the auxiliary material using sugar-free, make the patient of diabetes, hyperglycaemia can also take, expand using crowd.3rd, through result of the test
Select optimum experimental condition for：Solvent dosage is 5 times of medicinal material, 2 hours extraction times.The dry cream obtained under this process conditions
Yield is 13.1%.
Embodiments of the present invention are described in further detail below in conjunction with embodiment.
Embodiment
Embodiment 1
It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method comprise the following steps：Raw material is money
Careless 100g, oriental wormwood 100g, Radix Isatidis 100g, Fructus Aurantii（Fry）67g, radix bupleuri（System）67g, radix scutellariae 100g, cape jasmine 67g, the fruit of Chinese magnoliavine
134g；The taste of the above eight, add the water of 5 times of amounts, soak 30~60 minutes, circumfluence distillation 2 hours, stand 8 hours, filtration, filtrate
Paste is concentrated under reduced pressure into, adds ethanol to make to stand 12 hours up to 50% containing determining alcohol, filtration, ethanol is recovered under reduced pressure to without alcohol taste, obtains
Relative density is 1.29~1.32（22oC is surveyed）Thick paste, add dextrin 214g and honey element 9.6g, mix, particle is made, do
It is dry, 320g is made, produces.
Experimental example 1
Technological parameter selects
Process choice Orthogonal experiment results are：
Factor level table
Orthogonal test conceptual design and result
By result of the test select optimum experimental condition for：Solvent dosage is 5 times of medicinal material, 2 hours extraction times.In this work
The dried cream yield obtained under the conditions of skill is 13.1%.
Dried cream yield that two kinds of techniques obtain difference 2.9%, illustrate among the preparation process of new method effective ingredient not by
Decompose, its medicament effective component is at utmost retained.
The effect of effect is evident from product is substantially increased after process innovation optimization as can be seen here.
Claims (1)
1. it is a kind of for liver and gall with control, liver-yang hyperactivity, the preparation method of the strongly fragrant medicine of fire, it is characterised in that step is as follows：
（1）Desmodium 100g, oriental wormwood 100g, Radix Isatidis 100g, stir-fry Fructus Aurantii 67g, radix bupleuri 67g processed, radix scutellariae 100g, cape jasmine 67g, five
Taste 134g；
（2）The taste of the above eight, add the water of 5 times of amounts, soak 30~60 minutes, circumfluence distillation 2 hours, stand 8 hours, filtration；
（3）Filtrate decompression is condensed into paste, adds ethanol to make to stand 12 hours up to 50% containing determining alcohol；
（4）Filtration, ethanol is recovered under reduced pressure to without alcohol taste, the thick paste that relative density is 1.29~1.32 is obtained in 22oC；
（5）Dextrin 214g and honey element 9.6g is added, mixes, particle is made, dries, 320g is made, produces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510387084.3A CN104922278B (en) | 2015-07-06 | 2015-07-06 | It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510387084.3A CN104922278B (en) | 2015-07-06 | 2015-07-06 | It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104922278A CN104922278A (en) | 2015-09-23 |
| CN104922278B true CN104922278B (en) | 2017-12-29 |
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| CN201510387084.3A Active CN104922278B (en) | 2015-07-06 | 2015-07-06 | It is a kind of for liver and gall with control, liver-yang hyperactivity, the strongly fragrant medicine of fire and preparation method |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106491805A (en) * | 2016-10-27 | 2017-03-15 | 吴安相 | A kind of Chinese medicine formula for treating acute icterohepatitises |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368208A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano medicine 'Ganfu' and its preparing process |
| CN103055288A (en) * | 2012-12-29 | 2013-04-24 | 段绪川 | Chinese herbal medicine for treating acute cholangitis |
| CN103212048A (en) * | 2013-04-12 | 2013-07-24 | 刘长江 | Traditional Chinese medicine for treating hepatobiliary diseases |
-
2015
- 2015-07-06 CN CN201510387084.3A patent/CN104922278B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368208A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano medicine 'Ganfu' and its preparing process |
| CN103055288A (en) * | 2012-12-29 | 2013-04-24 | 段绪川 | Chinese herbal medicine for treating acute cholangitis |
| CN103212048A (en) * | 2013-04-12 | 2013-07-24 | 刘长江 | Traditional Chinese medicine for treating hepatobiliary diseases |
Non-Patent Citations (1)
| Title |
|---|
| 和肝利胆颗粒提取工艺研究;胡北等;《中国药师》;20141231;第17卷(第4期);565-567 * |
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| CN104922278A (en) | 2015-09-23 |
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Inventor after: Du Mingzhu Inventor after: Wei Jianhua Inventor after: Wang Donghai Inventor before: Du Mingzhu |
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