CN103461675A - Livestock and poultry intestinal tract regulator and preparation method thereof - Google Patents

Livestock and poultry intestinal tract regulator and preparation method thereof Download PDF

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Publication number
CN103461675A
CN103461675A CN2013104341335A CN201310434133A CN103461675A CN 103461675 A CN103461675 A CN 103461675A CN 2013104341335 A CN2013104341335 A CN 2013104341335A CN 201310434133 A CN201310434133 A CN 201310434133A CN 103461675 A CN103461675 A CN 103461675A
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parts
livestock
poultry
intestinal tract
enteric modulators
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CN103461675B (en
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杨振豪
李灵娟
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Henan Soar Veterinary Pharmaceutical Co Ltd
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Henan Soar Veterinary Pharmaceutical Co Ltd
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Abstract

The invention discloses a livestock and poultry intestinal tract regulator which comprises the following components in parts by weight: 30-60 parts of acidifying agent, 10-50 parts of prebiotics, 20-50 parts of intestinal tract endotoxin antagonist and 5-40 parts of auxiliary ingredients. The livestock and poultry intestinal tract regulator scientifically combines a plurality of functional additives, takes various etiological factors of clinical intestinal tract diseases into consideration, is wide in application range and obvious in effect, has no residues and no hidden food safety hazard compared with antibiotics, and is applicable to the function regulation of intestinal tracts of livestock and poultry; the intestinal tract functions of animals in large-scale cultivation process can be improved, and the animal feeding efficiency can be further increased. The intestinal tract regulator can be applicable to drinking water, does not add antibiotics, has no food sanitation and safety risks, and is stable in character and high in safety.

Description

Enteric modulators and preparation method thereof for a kind of livestock and poultry
Technical field
The invention belongs to the animal health-care product technical field, be specifically related to enteric modulators and preparation method thereof for a kind of livestock and poultry.
Background technology
In the feeding process of poultry and livestock, often occur because of ight soil anomalies such as having loose bowels of extremely causing of function of intestinal canal, punishments in advance, this can cause the price of deed lowly, the bad results such as production performance reduction.Veterinary clinic is often used antibiotic formulations to solve Similar Problems, but is using antibiotic in some bad consequences of the simultaneous of dealing with problems, such as the residual problem of imbalance, medicine of antibiotic toxic and side effect, microbial population of animal intestinal tract and environmental pollution etc.
Along with the attention of society to the food sanitation safe problem, antibiotic application will be subject to more restriction, therefore be badly in need of a kind of animal health-care product that can effectively solve the animal and bird intestines problem of green.
Summary of the invention
The object of the present invention is to provide livestock and poultry enteric modulators a kind of green, that can effectively solve the animal and bird intestines problem, the preparation method of this enteric modulators is provided simultaneously.
For achieving the above object, the present invention adopts following technical scheme:
A kind of livestock and poultry enteric modulators, is characterized in that, by the one-tenth of following weight portion, is grouped into: acidulant 30-60 part, prebiotics 10-50 part, intestinal endotoxin antagonist 20-50 part, auxiliary material 5-40 part.
Preferably, described enteric modulators is grouped into by the one-tenth of following weight portion: acidulant 30-50 part, prebiotics 15-40 part, intestinal endotoxin antagonist 20-40 part, auxiliary material 5-40 part.
Above-mentioned livestock and poultry are with in enteric modulators, and described acidulant is one or more in fumaric acid, citric acid, sodium butyrate; Described prebiotics is one or more in xylo-oligosaccharide, manna oligosacchride, FOS; Described intestinal endotoxin antagonist is one or more in taurine, sodium taurocholate, pectin; Described auxiliary material is one or more in DEXTROSE ANHYDROUS, water soluble starch.
The preparation method of enteric modulators for above-mentioned livestock and poultry comprises the following steps: by acidulant, prebiotics, intestinal endotoxin antagonist in proportion umber be pulverized and mixed evenly, more proportionally add auxiliary materials and mixing to get final product.
Livestock and poultry of the present invention are mainly used by drinking-water or spice mixed feeding with enteric modulators.
Livestock and poultry of the present invention with the combination of enteric modulators science several functional additives, considered the multi-pathogenesis of clinical intestines problem, applied widely, successful, compare the enteric modulators noresidue with antibiotic, without food security hidden danger, contribute to improve the function of intestinal canal of animal in the large-scale farming process, and then improve the efficiency of letting animals feed.Enteric modulators of the present invention can not add antibiotic for drinking-water applicable (distinguishing common feed addictive), there is no the food sanitation safe risk, and stable in properties, safe.Preparation method of the present invention is simple, use conventional equipment, with low cost, be convenient to promote.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, but protection scope of the present invention is not limited in this.
embodiment 1
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: (wherein fumaric acid is 20 parts for 35 parts of acidulants; 15 parts of sodium butyrates), 20 parts of prebioticses (xylo-oligosaccharide), intestinal endotoxin antagonist 35 parts (wherein sodium taurocholate is 15 parts, 20 parts of taurines), auxiliary material (DEXTROSE ANHYDROUS) are 10 parts.
The preparation method of enteric modulators for livestock and poultry: by acidulant, prebiotics, intestinal endotoxin antagonist in proportion umber pulverized 40 mesh sieves, then mix, more proportionally add auxiliary materials and mixing to get final product.
embodiment 2
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: 20 parts of 30 parts of acidulants (citric acid), 25 parts of prebioticses (xylo-oligosaccharide), intestinal endotoxin antagonist 35 parts (wherein pectin is 15 parts, 20 parts of taurines), auxiliary materials (DEXTROSE ANHYDROUS).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 3
The livestock and poultry enteric modulators, be grouped into by the one-tenth of following weight portion: 50 parts of acidulants (fumaric acid), 30 parts of prebioticses (xylo-oligosaccharide), 25 parts of intestinal endotoxin antagonists (sodium taurocholate), 5 parts of auxiliary materials (water soluble starch).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 4
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: 8 parts of 47 parts of acidulants (sodium butyrate), 25 parts of prebioticses (manna oligosacchride), intestinal endotoxin antagonist 20 parts (wherein sodium taurocholate is 10 parts, 10 parts of taurines), auxiliary materials (water soluble starch).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 5
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: (wherein fumaric acid is 10 parts for 35 parts of acidulants; 25 parts of sodium butyrates), (wherein FOS is 15 parts for 35 parts of prebioticses; 20 parts of manna oligosacchrides), intestinal endotoxin antagonist 20 parts (wherein sodium taurocholate is 10 parts, 10 parts of taurines), auxiliary material (water soluble starch) are 10 parts.
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 6
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: (wherein fumaric acid is 10 parts for 60 parts of acidulants; 25 parts of sodium butyrates; 25 parts of citric acids), (wherein FOS is 10 parts for 50 parts of prebioticses; 20 parts of manna oligosacchrides, 20 parts of xylo-oligosaccharides), (wherein sodium taurocholate is 10 parts, 10 parts of taurines for 40 parts of intestinal endotoxin antagonists; 20 parts of pectin), 40 parts of auxiliary materials (wherein water soluble starch is 25 parts, 15 parts of DEXTROSE ANHYDROUSs).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 7
The livestock and poultry enteric modulators; one-tenth by following weight portion is grouped into: (wherein sodium butyrate is 25 parts for 50 parts of acidulants; 25 parts of citric acids), (wherein FOS is 10 parts for 40 parts of prebioticses; 30 parts of xylo-oligosaccharides), (wherein sodium taurocholate is 20 parts for 50 parts of intestinal endotoxin antagonists; 10 parts of taurines; 20 parts of pectin), 30 parts of auxiliary materials (wherein water soluble starch is 25 parts, 5 parts of DEXTROSE ANHYDROUSs).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
embodiment 8
The livestock and poultry enteric modulators, one-tenth by following weight portion is grouped into: (wherein sodium butyrate is 25 parts for 40 parts of acidulants, 15 parts of fumaric acids), 15 parts of prebioticses (FOS), 20 parts of intestinal endotoxin antagonists (pectin), 25 parts of auxiliary materials (wherein water soluble starch is 10 parts, 15 parts of DEXTROSE ANHYDROUSs).
Livestock and poultry use the preparation method of enteric modulators with embodiment 1.
Stability checking: embodiment 1,2,4,6 is prepared to the gained enteric modulators and package with commercially available commonly used packing the (aluminium foil bag), be placed in the stability test case, make regular check on stability, after 3 months, do not find stability problem.
Water-soluble checking: get respectively embodiment 1,2,5,8 and prepare gained enteric modulators 1.0 grams and be dissolved in 50ml water, according to water-soluble detection method operation, the result proof is water-soluble good.
Utilize embodiment 3 to prepare the gained enteric modulators broiler chicken son is tested, observe the impact of its Escherichia coli on meat chick cecal content, Bifidobacterium and Bacillus acidi lactici.Test method is as follows:
Adopt the single-factor RANDOMIZED BLOCK DESIGN, select 60 healthy 817 meat chicks of 1 age in days, be divided at random 2 groups, establish 3 repetitions for every group, each repeats 10 chickens (male and female half and half), and experimental period is 1-6 week, and control group is all fed to basal diet, drinks clean drinking water.In experimental group drinking water on daytime every day, add embodiment 3 to prepare the gained enteric modulators, drink 8 hours by 0.05% mass concentration, other times are freely drunk clear water.Carry out 42 days experimental periods according to the feeding and management of conventional meat chick.Enteron aisle microstructure to broiler chicken when 3 week age is observed, during 3 week age enteric modulators on the impact of enteron aisle microstructure in Table 1.
Impact (the unit: μ m) of table 1 enteric modulators on the enteron aisle microstructure
Figure 272991DEST_PATH_IMAGE001
Annotate: the different significant differences that mean of shoulder mark
Result shows that enteric modulators can increase muscle chicken height of naps, reduces the crypts degree of depth, so enteric modulators can play the effect that promotes digestion, obvious to the health-care effect of Intestine of Broiler health .

Claims (4)

1. a livestock and poultry enteric modulators, is characterized in that, by the one-tenth of following weight portion, is grouped into: acidulant 30-60 part, prebiotics 10-50 part, intestinal endotoxin antagonist 20-50 part, auxiliary material 5-40 part.
2. livestock and poultry enteric modulators as claimed in claim 1, is characterized in that, by the one-tenth of following weight portion, is grouped into: acidulant 30-50 part, prebiotics 15-40 part, intestinal endotoxin antagonist 20-40 part, auxiliary material 5-40 part.
3. livestock and poultry enteric modulators as claimed in claim 1 or 2, is characterized in that, described acidulant is one or more in fumaric acid, citric acid, sodium butyrate; Described prebiotics is one or more in xylo-oligosaccharide, manna oligosacchride, FOS; Described intestinal endotoxin antagonist is one or more in taurine, sodium taurocholate, pectin; Described auxiliary material is one or more in DEXTROSE ANHYDROUS, water soluble starch.
4. the preparation method of enteric modulators for the arbitrary described livestock and poultry of claim 1-3, it is characterized in that, comprise the following steps: by acidulant, prebiotics, intestinal endotoxin antagonist in proportion umber be pulverized and mixed evenly, more proportionally add auxiliary materials and mixing to get final product.
CN201310434133.5A 2013-09-23 2013-09-23 Livestock and poultry intestinal tract regulator and preparation method thereof Expired - Fee Related CN103461675B (en)

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CN104770596A (en) * 2015-04-07 2015-07-15 中国水产科学研究院珠江水产研究所 Aquatic animal intestinal regulator and application thereof
CN105815545A (en) * 2015-01-06 2016-08-03 中粮集团有限公司 Organic acids composition and application and preparation
CN107397066A (en) * 2016-05-18 2017-11-28 中创云牧科技咨询(北京)股份有限公司 One kind acidifying milk and preparation method thereof and application method
CN107397055A (en) * 2016-05-18 2017-11-28 中创云牧科技咨询(北京)股份有限公司 One kind acidifying milk and preparation method thereof and application method
CN107996857A (en) * 2017-12-14 2018-05-08 南昌傲农生物科技有限公司 A kind of liquid amino acid vitamine supplement for reducing weaning stress of piglet and preparation method and application
CN108185148A (en) * 2018-03-23 2018-06-22 四川省畜牧科学研究院 A kind of easy processing compound premix for improving wean rabbit diarrhea
CN108208350A (en) * 2017-12-28 2018-06-29 广州和仕康生物技术有限公司 A kind of benefit iron hematopoiesis composition and preparation method thereof
CN111346221A (en) * 2019-12-23 2020-06-30 中国农业科学院北京畜牧兽医研究所 Health product for young poultry to open mouth and preparation method thereof
CN113397037A (en) * 2021-05-27 2021-09-17 福州一诺维生物科技有限公司 Intestinal flora regulator for livestock and poultry breeding and preparation method thereof
CN115702664A (en) * 2021-08-04 2023-02-17 安琪酵母股份有限公司 Livestock and poultry drinking water agent rich in yeast active components and application thereof

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Publication number Priority date Publication date Assignee Title
CN104366028A (en) * 2014-10-27 2015-02-25 天津农学院 Additive for improving foster nursing performance of cubs of fur animals and preparation method of additive
CN105815545A (en) * 2015-01-06 2016-08-03 中粮集团有限公司 Organic acids composition and application and preparation
CN104770596A (en) * 2015-04-07 2015-07-15 中国水产科学研究院珠江水产研究所 Aquatic animal intestinal regulator and application thereof
CN107397066A (en) * 2016-05-18 2017-11-28 中创云牧科技咨询(北京)股份有限公司 One kind acidifying milk and preparation method thereof and application method
CN107397055A (en) * 2016-05-18 2017-11-28 中创云牧科技咨询(北京)股份有限公司 One kind acidifying milk and preparation method thereof and application method
CN107996857A (en) * 2017-12-14 2018-05-08 南昌傲农生物科技有限公司 A kind of liquid amino acid vitamine supplement for reducing weaning stress of piglet and preparation method and application
CN108208350A (en) * 2017-12-28 2018-06-29 广州和仕康生物技术有限公司 A kind of benefit iron hematopoiesis composition and preparation method thereof
CN108185148A (en) * 2018-03-23 2018-06-22 四川省畜牧科学研究院 A kind of easy processing compound premix for improving wean rabbit diarrhea
CN111346221A (en) * 2019-12-23 2020-06-30 中国农业科学院北京畜牧兽医研究所 Health product for young poultry to open mouth and preparation method thereof
CN113397037A (en) * 2021-05-27 2021-09-17 福州一诺维生物科技有限公司 Intestinal flora regulator for livestock and poultry breeding and preparation method thereof
CN115702664A (en) * 2021-08-04 2023-02-17 安琪酵母股份有限公司 Livestock and poultry drinking water agent rich in yeast active components and application thereof

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