CN102771683B - Bacillus-subtilis-contained artificial milk extract premix for pigs and application of premix - Google Patents
Bacillus-subtilis-contained artificial milk extract premix for pigs and application of premix Download PDFInfo
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- CN102771683B CN102771683B CN2012103131142A CN201210313114A CN102771683B CN 102771683 B CN102771683 B CN 102771683B CN 2012103131142 A CN2012103131142 A CN 2012103131142A CN 201210313114 A CN201210313114 A CN 201210313114A CN 102771683 B CN102771683 B CN 102771683B
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Abstract
The invention provides a bacillus-subtilis-contained artificial milk extract premix for pigs and application of the premix. According to the prescription, the premix comprises the following components in percentage by weight; 30%-60% of carrier, 1%-4% of bacillus subtilis, 1%-4% of lactobacillus acidophilus, 3%-10% of coated zinc oxide, 1%-2% of chitosan oligosaccharide, 1%-2% of mannan oligosaccharide, 1%-3% of compound enzyme preparation, 10%-30% of lysine, 10%-40% of methionine, and 1%-5% of sweetener. The bacillus-subtilis-contained artificial milk extract premix can be used for improving the immunity of piglets, enhancing the feed digestibility, emarkably decreasing the diarrhea rate of weaned piglets, and improving the physical conditions of the piglets, thus greatly improving the production performance of the weaned piglets.
Description
Technical field
The present invention relates to field of fodder, be specifically related to a kind of artificial milk extract premix and application for pig containing bacillus subtilis.
Background technology
In recent years, China's grice diarrhoea is very general, and grice diarrhoea has become the restriction piglet growth, causes the key factor of piglet high mortality.The piglet that 30kg is following, the average of the whole year incidence of disease is 46.5%, the death rate reaches 15%.The grice diarrhoea high mortality mainly occurs in the newborn piglet of 1～3 age in days, the sucking pig of 7～20 ages in days and the piglet of the rear 10～15d of wean.Grice diarrhoea causes price of deed rate low, and piglet survival ratio descends, and piglet growth is slow, grows and stagnates even death, to pig industry, brings huge economic loss.Therefore, effectively prevent and treat the loss that grice diarrhoea can significantly reduce pig industry, pig industry is had to important economic worth.
Summary of the invention
The objective of the invention is for the problems referred to above, provide a kind of and can prevent grice diarrhoea, the artificial milk extract premix that promotes pigling immunity, improves feed digestibility, improves Production Performance of Weaning Pigs.
For achieving the above object, technical scheme provided by the invention is, a kind of artificial milk extract premix pig for containing bacillus subtilis, and calculation by weight percentage, the formula of described premix is as follows:
Preferably, the formula of described premix is as follows:
Preferably, described carrier is one or both and the two or more combination in lactose, soluble starch, corn protein powder, rice protein.
Preferably, described bacillus subtilis is ACCC10619.
Preferably, described lactobacillus acidophilus is ACCC10637.
Preferably, described complex enzyme formulation comprises one or both and the two or more combinations in beta-xylanase, 1,4 beta-glucanase, protease, a-amylase.
Preferably, in described complex enzyme formulation, beta-xylanase is not less than 8000U/g; Described 1,4 beta-glucanase is not less than 300U/g; Described protease is not less than 1000U/g; Described a-amylase is not less than 2000U/g.
The present invention also provides the application of a kind of pig containing bacillus subtilis with artificial milk extract premix, add the described artificial milk extract premix for pig containing bacillus subtilis in the basal diet of weanling pig, making the described pig containing bacillus subtilis is 1.5%～2.5% with the addition of artificial milk extract premix in basal diet.
Preferably, the application of artificial milk extract premix for the described pig containing bacillus subtilis, add the described artificial milk extract premix for pig containing bacillus subtilis in the basal diet of weanling pig, making the described pig containing bacillus subtilis is 2% with the addition of artificial milk extract premix in basal diet.
The present invention prevents grice diarrhoea from the following aspects:
(1) add bacillus subtilis (Bacillus subtilis), lactobacillus acidophilus (Lactobacillus acidophilus), chitosan oligosaccharide and manna oligosacchride in the present invention, they are with different formula combination, both improved the health status of animal, can replace antibiotic again, guaranteed the security of feed, and to useful endogenous and all nutritious effects of exogenous probio, by changing or rebuilding the enteric microorganism flora and then improve the piglet general level of the health.
(2) the present invention adds coated zinc oxide.High zinc gets the nod to the effect of grice diarrhoea, yet adds high zinc in feed, and the side effects such as its antagonism and high pollution highlight day by day.The present invention has replaced common zinc oxide with coated zinc oxide; protection because of its coating material; can reduce its dissociating in stomach and small intestine; guarantee that major part can arrive hindgut performance effect with the zinc oxide molecular state; thereby minimizing using dosage; not only the pig production performance can be improved, the heavy metal pollution of feed can be controlled again.
(3) added complex enzyme formulation in the present invention.Because domestic main feed still be take common Corn-soybean-fish meal-whey powder type sucking pig material as main, especially take vegetable raw material as main, and contain SNSP (NSP) the class ANFs such as a large amount of xylans, beta glucan, mannosan in vegetable raw material, these SNSPs not only can not be digested by sucking pig, absorb, affect on the contrary digestion, the utilization of the nutrients such as starch, protein by forming the approach such as plant cell wall, increase chyme viscosity, in the stress of baby pigs caused ablaction process, high antigen is larger on the diarrhoea impact of piglet.Therefore the present invention has added the zytase that can digest SNSP, 1,4 beta-glucanase, amylase etc., can effectively alleviate piglet to these ANFs stress.
Therefore, the present invention can promote pigling immunity, raising feed digestibility, significantly reduces the diarrhea rate of weanling pig, improve the physical condition of piglet, thereby significantly improves the production performance of weanling pig.
The specific embodiment
Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiment only are not used in and limit the scope of the invention for the present invention is described.Should be understood that in addition, after having read content of the present invention, those skilled in the art can make various changes or modifications the present invention, these equivalent form of values fall within the application's limited range equally.
Embodiment 1,
At first take following raw material: corn protein powder: 42kg; Bacillus subtilis 2.5kg; Lactobacillus acidophilus: 2kg; Coated zinc oxide: 10kg; Chitosan oligosaccharide: 1kg; Manna oligosacchride: 2kg; Complex enzyme formulation: 3kg; Lysine: 10kg; Methionine: 25kg; Sweetener: 2.5kg.
Above-mentioned raw materials is mixed, can obtain the present invention.
During use, 2.5% the addition by the present invention according to weight, add in the basal diet of piglet, mixes, and routine is fed and got final product.
Embodiment 2,
At first take following raw material: soybean protein: 35kg; Bacillus subtilis 1kg; Lactobacillus acidophilus: 4kg; Coated zinc oxide: 6kg; Chitosan oligosaccharide: 2kg; Manna oligosacchride: 2kg; Complex enzyme formulation: 1.5kg; Lysine: 15kg; Methionine: 32kg; Sweetener: 1.5kg.
Above-mentioned raw materials is mixed, can obtain the present invention.
During use, 2% the addition by the present invention according to weight, add in the basal diet of piglet, mixes, and routine is fed and got final product.
Embodiment 3,
At first accurately take following raw material: rice protein: 50kg; Bacillus subtilis: 2.5kg; Lactobacillus acidophilus: 1kg; Coated zinc oxide: 5kg; Chitosan oligosaccharide: 2kg; Manna oligosacchride: 1kg; Complex enzyme formulation: 2.5kg; Lysine: 10kg; Methionine: 25kg; Sweetener: 1kg.
Above-mentioned raw materials is mixed, can obtain the present invention.
During use, 1.5% the addition by the present invention according to weight, add in the basal diet of piglet, mixes, and routine is fed and got final product.
Embodiment 4,
At first accurately take following raw material: soluble starch: 60kg; Bacillus subtilis 2kg; Lactobacillus acidophilus: 2kg; Coated zinc oxide: 8kg; Chitosan oligosaccharide: 1kg; Manna oligosacchride: 1kg; Complex enzyme formulation: 1.5kg; Lysine: 12kg; Methionine: 10kg; Sweetener: 2.5kg.
Above-mentioned raw materials is mixed, can obtain the present invention.
During use, 2.5% the addition by the present invention according to weight, add in the basal diet of piglet, mixes, and routine is fed and got final product.
Embodiment 5,
At first accurately take following raw material: rice protein: 50kg; Bacillus subtilis 2.5kg; Lactobacillus acidophilus: 1kg; Coated zinc oxide: 5kg; Chitosan oligosaccharide: 2kg; Manna oligosacchride: 1kg; Complex enzyme formulation: 2.5kg; Lysine: 10kg; Methionine: 25kg; Sweetener: 1kg.
Above-mentioned raw materials is mixed, can obtain the present invention.
During use, 2% the addition by the present invention according to weight, add in the basal diet of piglet, mixes, and routine is fed and got final product.
Embodiment 6,
The impact of test the present invention on Production Performance of Weaning Pigs
6.1 experimental design
6.1.1 experimental animal and material
Select 15,25 age in days left and right, consistent, the individual wean uniformly of kind pig 11 ，Mei hurdle, hurdle, be divided at random 4 groups, each test group column home term harmonization, duration of test is avoided vaccinating as far as possible.
6.1.2 method for breeding
Test 7.5 days by a definite date, duration of test is respectively organized the equal free choice feeding of pig, automatic water-drinking, and test pig immunity, sterilization etc. are undertaken by the pig farm routine.
Method for breeding is as follows:
Embodiment 6.1: add the present invention 1.5% in the Corn-soybean daily ration.
Embodiment 6.2: add the present invention 2% in the Corn-soybean daily ration.
Embodiment 6.3: add the present invention 2.5% in the Corn-soybean daily ration.
Control group: establish blank Corn-soybean daily ration group.
6.1.3 testing index
Initial weight, end weight, daily ingestion amount, feedstuff-meat ratio.
6.2 test results and analysis
Table 1: the impact of different embodiment on daily gain in pigs
No matter as can be seen from Table 1, added 3 groups of embodiment of the present invention and do not compared with adding control group of the present invention, be daily ingestion amount or adding weight, and advantage is largely arranged; In the situation that initial weight is more or less the same, the end of 3 groups of embodiment is heavy also much bigger than control group; Finally calculate the feedstuff-meat ratio of gained, 3 groups of embodiment are significantly less than control group.
Embodiment 6.1 daily ingestion amounts are than the high 50g of control group (17.9%); Daily gain is than the high 93g of control group (45.6%), and feedstuff-meat ratio is low by 0.27 simultaneously, and approximately 19.6%.
Embodiment 6.2 shows advantage than control group especially at daily ingestion amount, daily gain and feedstuff-meat ratio three aspects:, than the daily ingestion amount of control group and daily gain difference high 71g (25.4%), 114g (55.9%), feedstuff-meat ratio is lower by 0.28 (20.3%) than control group simultaneously.
Embodiment 6.3 daily ingestion amounts are than the high 65g of control group (23.2%); Daily gain is than the high 103g of control group (50.5%), and feedstuff-meat ratio is low by 0.26 simultaneously, and approximately 18.8%.
6.3 conclusion
No matter it is all relative poor not add control group daily ingestion amount of the present invention, daily gain and feedstuff-meat ratio, and added 3 groups of embodiment of the present invention aspect daily ingestion amount, daily gain and feedstuff-meat ratio all tool have great advantage, absolutely proved the effect of the present invention aspect raising pigling immunity, raising digestibility, and due to the enhancing of pigling immunity, the diarrhea rate of piglet also obviously descends, the physical condition of piglet improves greatly, from and significantly improved the production performance of piglet.
And, in 3 groups of embodiment, the production performance effect that embodiment 6.2 feeds after weanling pig is best, be secondly embodiment 6.3 and 6.1, illustrate that adding 2% weight the present invention is optimum addition.
The present invention is any combination in following scope:
A kind of artificial milk extract premix for pig containing bacillus subtilis, calculate by weight percentage, and the formula of described premix is as follows:
The present invention can promote pigling immunity, raising feed digestibility, significantly reduces the diarrhea rate of weanling pig, improve the physical condition of piglet, thereby significantly improves the production performance of weanling pig.
Be more than the description to the embodiment of the present invention, by the above-mentioned explanation to the disclosed embodiments, make professional and technical personnel in the field can realize or use the present invention.Multiple modification to these embodiment will be apparent for those skilled in the art, and General Principle as defined herein can be in the situation that do not break away from the spirit or scope of the present invention, realization in other embodiments.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (7)
1. the artificial milk extract premix for pig containing bacillus subtilis, is characterized in that, calculates by weight percentage, and the formula of described premix is as follows:
2. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 1, is characterized in that, calculates by weight percentage, and the formula of described premix is as follows:
3. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 1 or 2, is characterized in that, one or more the combination that described carrier is lactose, soluble starch, corn protein powder, rice protein, soybean protein.
4. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 1 or 2, is characterized in that, described bacillus subtilis is ACCC10619.
5. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 1 or 2, is characterized in that, described lactobacillus acidophilus is ACCC10637.
6. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 1 or 2, is characterized in that, described complex enzyme formulation comprises one or more the combination in beta-xylanase, 1,4 beta-glucanase, protease, a-amylase.
7. the artificial milk extract premix for pig containing bacillus subtilis as claimed in claim 6, is characterized in that, in described complex enzyme formulation, beta-xylanase is not less than 8000U/g; Described 1,4 beta-glucanase is not less than 300U/g; Described protease is not less than 1000U/g; Described a-amylase is not less than 2000U/g.
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103404706A (en) * | 2013-08-09 | 2013-11-27 | 江苏天石生物科技有限公司 | Probiotics and prebiotics mixed feed additive |
| CN104366073A (en) * | 2014-11-03 | 2015-02-25 | 河南联合英伟饲料有限公司 | 4% functional non-antibiotic piglet premix |
| CN104543389A (en) * | 2014-12-25 | 2015-04-29 | 青岛颂田生物技术有限公司 | Efficient green chitosan oligosaccharide compound agricultural additive |
| CN105076724A (en) * | 2015-08-28 | 2015-11-25 | 成都力源天海生物工程有限公司 | Biological fodder without antibiotic for livestock and poultry, preparing method thereof and feces safety disposal method |
| CN106071233A (en) * | 2016-06-21 | 2016-11-09 | 湖北省农业科学院畜牧兽医研究所 | A kind of feed additive and method being applicable to produce drug residue free high quality pork |
| CN106135696B (en) * | 2016-07-02 | 2019-11-05 | 浙江大学 | Application of the CS-ZnO as intestine of young pigs mucosal immunity reinforcing agent |
| CN111513204B (en) * | 2016-11-10 | 2023-07-18 | 南京工业大学 | Application of feed additive in promoting intestinal development of weaned piglets |
| CN113632887A (en) * | 2021-06-07 | 2021-11-12 | 西南大学 | Preparation method and application of pig feeding accelerant |
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Address after: 215000 Jiangsu city of Suzhou province Taicang city Shaxi town Xingang Yuewang Road No. 239 Patentee after: ANYOU BIOTECHNOLOGY GROUP CO., LTD. Address before: 215000 Jiangsu city of Suzhou province Taicang city Shaxi town Xingang Yuewang Road No. 239 Patentee before: Anyou Biological Technology Group Co., Ltd. |