CN101610771A - 肝癌治疗剂 - Google Patents

肝癌治疗剂 Download PDF

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Publication number
CN101610771A
CN101610771A CNA200880005174XA CN200880005174A CN101610771A CN 101610771 A CN101610771 A CN 101610771A CN A200880005174X A CNA200880005174X A CN A200880005174XA CN 200880005174 A CN200880005174 A CN 200880005174A CN 101610771 A CN101610771 A CN 101610771A
Authority
CN
China
Prior art keywords
cancer
rifampicin
derivatives
liver
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA200880005174XA
Other languages
English (en)
Chinese (zh)
Inventor
七里真义
河野裕
原刚
牧野弘
平井美和
增田尊信
杉本正信
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Medical and Dental University NUC
Genecare Research Institute Co Ltd
Original Assignee
Tokyo Medical and Dental University NUC
Genecare Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Medical and Dental University NUC, Genecare Research Institute Co Ltd filed Critical Tokyo Medical and Dental University NUC
Publication of CN101610771A publication Critical patent/CN101610771A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNA200880005174XA 2007-02-15 2008-02-14 肝癌治疗剂 Pending CN101610771A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007034960A JP2010111582A (ja) 2007-02-15 2007-02-15 リファンピシンを成分とする肝臓癌治療剤
JP034960/2007 2007-02-15

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012102751684A Division CN102793702A (zh) 2007-02-15 2008-02-14 肝癌治疗剂

Publications (1)

Publication Number Publication Date
CN101610771A true CN101610771A (zh) 2009-12-23

Family

ID=39690110

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2012102751684A Pending CN102793702A (zh) 2007-02-15 2008-02-14 肝癌治疗剂
CNA200880005174XA Pending CN101610771A (zh) 2007-02-15 2008-02-14 肝癌治疗剂

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2012102751684A Pending CN102793702A (zh) 2007-02-15 2008-02-14 肝癌治疗剂

Country Status (3)

Country Link
JP (1) JP2010111582A (ja)
CN (2) CN102793702A (ja)
WO (1) WO2008099883A1 (ja)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4393098B2 (ja) * 2002-06-21 2010-01-06 独立行政法人科学技術振興機構 アンサマイシン系抗生物質の新規用途及び新規血管新生抑制物質のスクリーニング方法

Also Published As

Publication number Publication date
JP2010111582A (ja) 2010-05-20
WO2008099883A1 (ja) 2008-08-21
CN102793702A (zh) 2012-11-28

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