CA1081230A - Preparation d'amides d'acides (2-pyrimidinyl-thio) alcanoiques - Google Patents

Preparation d'amides d'acides (2-pyrimidinyl-thio) alcanoiques

Info

Publication number
CA1081230A
CA1081230A CA273,420A CA273420A CA1081230A CA 1081230 A CA1081230 A CA 1081230A CA 273420 A CA273420 A CA 273420A CA 1081230 A CA1081230 A CA 1081230A
Authority
CA
Canada
Prior art keywords
pyrimidinyl
xylidino
thio
formula
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA273,420A
Other languages
English (en)
Inventor
Carlo Scolastico
Giovanni Tronooni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lpb Istituto Farmaceutico SpA
Original Assignee
Lpb Istituto Farmaceutico SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lpb Istituto Farmaceutico SpA filed Critical Lpb Istituto Farmaceutico SpA
Application granted granted Critical
Publication of CA1081230A publication Critical patent/CA1081230A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
CA273,420A 1976-03-17 1977-03-08 Preparation d'amides d'acides (2-pyrimidinyl-thio) alcanoiques Expired CA1081230A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21317/76A IT1063074B (it) 1976-03-17 1976-03-17 Ammidi di acidi(z-pirimidiniltio)al canoici quali agent antilipemici

Publications (1)

Publication Number Publication Date
CA1081230A true CA1081230A (fr) 1980-07-08

Family

ID=11180012

Family Applications (1)

Application Number Title Priority Date Filing Date
CA273,420A Expired CA1081230A (fr) 1976-03-17 1977-03-08 Preparation d'amides d'acides (2-pyrimidinyl-thio) alcanoiques

Country Status (14)

Country Link
JP (1) JPS52113983A (fr)
BE (1) BE852401A (fr)
CA (1) CA1081230A (fr)
CH (1) CH631169A5 (fr)
DE (1) DE2711149C3 (fr)
DK (1) DK143558C (fr)
ES (1) ES456902A1 (fr)
FR (1) FR2344545A1 (fr)
GB (1) GB1532195A (fr)
IT (1) IT1063074B (fr)
MX (1) MX4818E (fr)
NL (1) NL166933C (fr)
PH (1) PH14865A (fr)
SE (1) SE434743B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5810525Y2 (ja) * 1978-08-04 1983-02-25 三菱電機株式会社 小型電気掃除機
IT1211096B (it) * 1981-08-20 1989-09-29 Lpb Ist Farm Pirimidine e s.triazinici adattivita' ipolipidemizzante.
JPS59199673A (ja) * 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
FR2636064B1 (fr) * 1988-09-08 1990-12-07 Fabre Sa Pierre Thioformamidines, leur preparation et leur application en tant que medicaments
JP2005501817A (ja) * 2001-06-12 2005-01-20 アクティブ パス ファーマシューティカルズ， インコーポレイテッド β−アミロイド産生を調節する化合物、組成物および方法

Also Published As

Publication number Publication date
PH14865A (en) 1982-01-08
SE7702922L (sv) 1977-09-18
NL7702821A (nl) 1977-09-20
FR2344545A1 (fr) 1977-10-14
JPS52113983A (en) 1977-09-24
JPS554746B2 (fr) 1980-01-31
DE2711149A1 (de) 1977-09-29
NL166933B (nl) 1981-05-15
IT1063074B (it) 1985-02-11
GB1532195A (en) 1978-11-15
DK114377A (da) 1977-09-18
ES456902A1 (es) 1978-01-16
SE434743B (sv) 1984-08-13
DE2711149C3 (de) 1980-12-11
NL166933C (nl) 1981-10-15
DK143558B (da) 1981-09-07
CH631169A5 (en) 1982-07-30
FR2344545B1 (fr) 1980-03-21
BE852401A (fr) 1977-07-01
MX4818E (es) 1982-10-20
DE2711149B2 (fr) 1980-04-24
DK143558C (da) 1982-03-22

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Legal Events

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