BRPI0300660B8 - method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c - Google Patents

method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c

Info

Publication number
BRPI0300660B8
BRPI0300660B8 BRPI0300660A BR0300660A BRPI0300660B8 BR PI0300660 B8 BRPI0300660 B8 BR PI0300660B8 BR PI0300660 A BRPI0300660 A BR PI0300660A BR 0300660 A BR0300660 A BR 0300660A BR PI0300660 B8 BRPI0300660 B8 BR PI0300660B8
Authority
BR
Brazil
Prior art keywords
cytochrome
mitochondrial release
release
mitochondrial
kit
Prior art date
Application number
BRPI0300660A
Other languages
Portuguese (pt)
Other versions
BR0300660A (en
BRPI0300660B1 (en
Inventor
E Vercesi Aníbal
Barbosa Ladeira Campos Claudia
Rottenberg Hagai
G Cosso Ricardo
F Castilho Roger
Original Assignee
Fapesp Fund De Amparo A Pesquisa Do Estado De Sao Paulo
Univ Estadual Campinas Unicamp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fapesp Fund De Amparo A Pesquisa Do Estado De Sao Paulo, Univ Estadual Campinas Unicamp filed Critical Fapesp Fund De Amparo A Pesquisa Do Estado De Sao Paulo
Priority to BRPI0300660A priority Critical patent/BRPI0300660B8/en
Publication of BR0300660A publication Critical patent/BR0300660A/en
Priority to PCT/BR2004/000022 priority patent/WO2004077007A2/en
Publication of BRPI0300660B1 publication Critical patent/BRPI0300660B1/en
Publication of BRPI0300660B8 publication Critical patent/BRPI0300660B8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/80—Cytochromes

Abstract

"método para quantificar liberação mitocondrial de citocromo c, composição para detectar liberação mitocondrial de citocromo c, kit para detectar liberação mitocondrial de citocromo c, uso de composição para liberação mitocondrial de citocromo c". é descrito método para quantificar a liberação mitocondrial de citocromo c durante a morte celular comportando permeabilização seletiva da membrana plasmática e imunodetecção de citocromo c. a invenção reporta-se, ainda, à composição para detectar liberação mitocondrial de citocromo c, kit para detectar liberação mitocondrial de citocromo c, bem como uso de composição para liberação mitocondrial de citocromo c."method to quantify mitochondrial release of cytochrome c, composition to detect mitochondrial release of cytochrome c, kit to detect mitochondrial release of cytochrome c, use of composition for mitochondrial release of cytochrome c". A method to quantify mitochondrial cytochrome c release during cell death is described, including selective permeabilization of the plasma membrane and immunodetection of cytochrome c. the invention also relates to the composition for detecting mitochondrial release of cytochrome c, kit to detect mitochondrial release of cytochrome c, as well as the use of composition for mitochondrial release of cytochrome c.

BRPI0300660A 2003-02-28 2003-02-28 method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c BRPI0300660B8 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0300660A BRPI0300660B8 (en) 2003-02-28 2003-02-28 method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c
PCT/BR2004/000022 WO2004077007A2 (en) 2003-02-28 2004-02-26 Detection, quantification and composition for cytochrome c released from mitochondria

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0300660A BRPI0300660B8 (en) 2003-02-28 2003-02-28 method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c

Publications (3)

Publication Number Publication Date
BR0300660A BR0300660A (en) 2003-10-14
BRPI0300660B1 BRPI0300660B1 (en) 2017-02-21
BRPI0300660B8 true BRPI0300660B8 (en) 2021-07-27

Family

ID=28679778

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0300660A BRPI0300660B8 (en) 2003-02-28 2003-02-28 method to quantify mitochondrial release of cytochrome c and kit to detect mitochondrial release of cytochrome c

Country Status (2)

Country Link
BR (1) BRPI0300660B8 (en)
WO (1) WO2004077007A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102334260B1 (en) 2013-03-14 2021-12-02 스미토모 다이니폰 파마 온콜로지, 인크. Jak2 and alk2 inhibitors and methods for their use
US11040038B2 (en) 2018-07-26 2021-06-22 Sumitomo Dainippon Pharma Oncology, Inc. Methods for treating diseases associated with abnormal ACVR1 expression and ACVR1 inhibitors for use in the same

Also Published As

Publication number Publication date
BR0300660A (en) 2003-10-14
BRPI0300660B1 (en) 2017-02-21
WO2004077007A2 (en) 2004-09-10
WO2004077007A3 (en) 2004-10-14

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25K Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: republication
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