BR0007448A - Uso de um inibidor de trombina de baixo peso molecular, solução de diálise, concentrado de diálise, kit de partes para uso em diálise, processo para a preparação de uma solução, ou de um concentrado, e, método de tratamento por diálise de um paciente necessitando de tal tratamento - Google Patents

Uso de um inibidor de trombina de baixo peso molecular, solução de diálise, concentrado de diálise, kit de partes para uso em diálise, processo para a preparação de uma solução, ou de um concentrado, e, método de tratamento por diálise de um paciente necessitando de tal tratamento

Info

Publication number
BR0007448A
BR0007448A BR0007448-9A BR0007448A BR0007448A BR 0007448 A BR0007448 A BR 0007448A BR 0007448 A BR0007448 A BR 0007448A BR 0007448 A BR0007448 A BR 0007448A
Authority
BR
Brazil
Prior art keywords
dialysis
treatment
concentrate
solution
molecular weight
Prior art date
Application number
BR0007448-9A
Other languages
English (en)
Inventor
Gunnar Fager
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0007448A publication Critical patent/BR0007448A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424—Substitution fluid path
    • A61M1/3427—Substitution fluid path back through the membrane, e.g. by inverted trans-membrane pressure [TMP]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

''USO DE UM INIBIDOR DE TROMBINA DE BAIXO PESO MOLECULAR, SOLUçãO DE DIáLISE, CONCENTRADO DE DIáLISE, KIT DE PARTES PARA USO EM DIáLISE, PROCESSO PARA A PREPARAçãO DE UMA SOLUçãO, OU DE UM CONCENTRADO, E, MéTODO DE TRATAMENTO POR DIáLISE D EUM PACIENTE NECESSITANDO DE TAL TRATAMENTO''. é proporcionado o uso de um inibidor de trombina de baixo peso molecular para a preparação de um medicamento para o tratamento por diálise, particularmente hemodiálise, de um paciente necessitando de tal tratamento, no qual o inibidor de trombina é proporcionado na solução de diálise, bem como concentrados e soluções de diálise incluindo inibidores de trombina de baixo peso molecular, tal como melagatran.
BR0007448-9A 1999-01-11 2000-01-11 Uso de um inibidor de trombina de baixo peso molecular, solução de diálise, concentrado de diálise, kit de partes para uso em diálise, processo para a preparação de uma solução, ou de um concentrado, e, método de tratamento por diálise de um paciente necessitando de tal tratamento BR0007448A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900043A SE9900043D0 (sv) 1999-01-11 1999-01-11 New use
PCT/SE2000/000030 WO2000041715A1 (en) 1999-01-11 2000-01-11 New dialysis method

Publications (1)

Publication Number Publication Date
BR0007448A true BR0007448A (pt) 2001-10-16

Family

ID=20414050

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0007448-9A BR0007448A (pt) 1999-01-11 2000-01-11 Uso de um inibidor de trombina de baixo peso molecular, solução de diálise, concentrado de diálise, kit de partes para uso em diálise, processo para a preparação de uma solução, ou de um concentrado, e, método de tratamento por diálise de um paciente necessitando de tal tratamento

Country Status (19)

Country Link
US (4) US20030042202A1 (pt)
EP (1) EP1144000B1 (pt)
JP (1) JP4054533B2 (pt)
KR (1) KR100840452B1 (pt)
CN (1) CN100387296C (pt)
AT (1) ATE316384T1 (pt)
AU (1) AU763185B2 (pt)
BR (1) BR0007448A (pt)
CA (1) CA2356440A1 (pt)
CY (1) CY1107461T1 (pt)
DE (1) DE60025698T2 (pt)
DK (1) DK1144000T3 (pt)
ES (1) ES2255968T3 (pt)
IL (1) IL143824A0 (pt)
NO (1) NO326996B1 (pt)
NZ (1) NZ512712A (pt)
SE (1) SE9900043D0 (pt)
WO (1) WO2000041715A1 (pt)
ZA (1) ZA200105274B (pt)

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Publication number Priority date Publication date Assignee Title
EP1466916B1 (en) 2002-09-09 2007-10-24 Trigen Limited Peptide boronic acids useful in making salts thereof
US7112572B2 (en) 2002-09-09 2006-09-26 Trigen Limited Multivalent metal salts of boronic acids
US7235589B2 (en) * 2004-09-21 2007-06-26 Bio Numerik Pharmaceuticals, Inc. Method of treating patients undergoing kidney dialysis
CN105115949B (zh) * 2005-12-21 2018-06-22 梅索斯卡莱科技公司 分析装置、方法和试剂
CA3122671A1 (en) 2005-12-21 2008-05-15 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
US20070155672A1 (en) * 2006-01-05 2007-07-05 Markus Voges Sterilized peritoneal dialysis solutions containing heparin
ES2647775T3 (es) * 2011-08-02 2017-12-26 Medtronic, Inc. Sistema de hemodiálisis que tiene una trayectoria de flujo con un volumen distensible controlado
US9623164B2 (en) 2013-02-01 2017-04-18 Medtronic, Inc. Systems and methods for multifunctional volumetric fluid control
US10010663B2 (en) 2013-02-01 2018-07-03 Medtronic, Inc. Fluid circuit for delivery of renal replacement therapies
US10850016B2 (en) 2013-02-01 2020-12-01 Medtronic, Inc. Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection
US10874787B2 (en) 2014-12-10 2020-12-29 Medtronic, Inc. Degassing system for dialysis
US9713665B2 (en) 2014-12-10 2017-07-25 Medtronic, Inc. Degassing system for dialysis
US10098993B2 (en) 2014-12-10 2018-10-16 Medtronic, Inc. Sensing and storage system for fluid balance
US11278654B2 (en) 2017-12-07 2022-03-22 Medtronic, Inc. Pneumatic manifold for a dialysis system
US11033667B2 (en) 2018-02-02 2021-06-15 Medtronic, Inc. Sorbent manifold for a dialysis system
US11110215B2 (en) 2018-02-23 2021-09-07 Medtronic, Inc. Degasser and vent manifolds for dialysis

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HU178398B (en) * 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4489535A (en) * 1980-10-02 1984-12-25 Veltman Preston Leonard Materials and method for preparing dialysis solutions containing bicarbonate ions
GR870129B (en) * 1987-01-27 1987-02-04 Giatzidis Ippokratis Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
US5549674A (en) * 1992-03-02 1996-08-27 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
DE4321444A1 (de) * 1993-06-28 1995-01-05 Bernd Prof Dr Clement Pharmazeutische Zubereitung
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
US5707966A (en) * 1994-03-04 1998-01-13 Eli Lilly And Company Antithrombotic agents
DE4443390A1 (de) * 1994-12-06 1996-06-13 Basf Ag Neue dipeptidische p-Amidinobenzylamide mit N-terminalen Sulfonyl- bzw. Aminosulfonylresten
KR19980702112A (ko) * 1995-02-10 1998-07-15 페라 스타르크,요헨 카르크 트롬빈 억제제
US5710130A (en) * 1995-02-27 1998-01-20 Eli Lilly And Company Antithrombotic agents
SE9600216D0 (sv) * 1996-01-18 1996-01-18 Hans Arne Hansson Styrning av läkningsprocesser
CZ291690B6 (cs) * 1996-02-13 2003-05-14 Akzo Nobel N. V. Inhibitory serinové proteázy a farmaceutický prostředek
EP0884325A1 (en) * 1997-04-24 1998-12-16 Akzo Nobel N.V. Thrombin inhibitors containing a peptidyl heterocycle
CA2288224A1 (en) * 1997-04-30 1998-11-05 Mary George Johnson Antithrombotic agents
AU7270798A (en) * 1997-05-01 1998-11-24 Eli Lilly And Company Antithrombotic agents
WO1998050420A1 (en) * 1997-05-02 1998-11-12 Akzo Nobel N.V. Serine protease inhibitors

Also Published As

Publication number Publication date
US20050153904A1 (en) 2005-07-14
EP1144000A1 (en) 2001-10-17
EP1144000B1 (en) 2006-01-25
CN1354673A (zh) 2002-06-19
AU2140900A (en) 2000-08-01
IL143824A0 (en) 2002-04-21
SE9900043D0 (sv) 1999-01-11
US20090192137A1 (en) 2009-07-30
KR100840452B1 (ko) 2008-06-20
US20030042202A1 (en) 2003-03-06
US20080004225A1 (en) 2008-01-03
JP2002534217A (ja) 2002-10-15
AU763185B2 (en) 2003-07-17
JP4054533B2 (ja) 2008-02-27
NZ512712A (en) 2004-09-24
ES2255968T3 (es) 2006-07-16
NO20013301D0 (no) 2001-07-03
NO20013301L (no) 2001-07-03
NO326996B1 (no) 2009-03-30
WO2000041715A1 (en) 2000-07-20
ATE316384T1 (de) 2006-02-15
CA2356440A1 (en) 2000-07-20
CY1107461T1 (el) 2012-12-19
DE60025698T2 (de) 2006-10-19
ZA200105274B (en) 2002-09-26
CN100387296C (zh) 2008-05-14
DE60025698D1 (de) 2006-04-13
KR20010093250A (ko) 2001-10-27
DK1144000T3 (da) 2006-05-08

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Legal Events

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O ART. 8O COMBINADO COM ART. 11 E ART. 10 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.