AU2001273461A1 - Methods for recombinatorial nucleic acid synthesis - Google Patents
Methods for recombinatorial nucleic acid synthesisInfo
- Publication number
- AU2001273461A1 AU2001273461A1 AU2001273461A AU7346101A AU2001273461A1 AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1 AU 2001273461 A AU2001273461 A AU 2001273461A AU 7346101 A AU7346101 A AU 7346101A AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1
- Authority
- AU
- Australia
- Prior art keywords
- recombinatorial
- methods
- nucleic acid
- acid synthesis
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/613,535 | 2000-07-10 | ||
US09/613,535 US6994963B1 (en) | 2000-07-10 | 2000-07-10 | Methods for recombinatorial nucleic acid synthesis |
PCT/US2001/022195 WO2002004630A2 (fr) | 2000-07-10 | 2001-07-10 | Procédés de synthèse recombinatoire d"acides nucléiques |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001273461A1 true AU2001273461A1 (en) | 2002-01-21 |
Family
ID=24457683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001273461A Abandoned AU2001273461A1 (en) | 2000-07-10 | 2001-07-10 | Methods for recombinatorial nucleic acid synthesis |
Country Status (3)
Country | Link |
---|---|
US (1) | US6994963B1 (fr) |
AU (1) | AU2001273461A1 (fr) |
WO (1) | WO2002004630A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7332308B1 (en) * | 1999-05-21 | 2008-02-19 | The Penn State Research Foundation | Incrementally truncated nucleic acids and methods of making same |
US7871799B2 (en) * | 2002-11-22 | 2011-01-18 | Lawrence Livermore National Security, Llc | Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions |
TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
US7501254B2 (en) * | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
DK2121920T3 (da) * | 2007-03-01 | 2011-11-21 | Symphogen As | Fremgangsmåde til kloning af sammenhørende antistoffer |
KR20110058861A (ko) * | 2008-08-29 | 2011-06-01 | 심포젠 에이/에스 | 조류 유래 항체의 클로닝 방법 |
KR102091207B1 (ko) | 2009-02-13 | 2020-03-20 | 엑스-켐, 인크. | Dna―코딩된 라이브러리의 생성 및 스크리닝 방법 |
EA032438B1 (ru) | 2011-09-07 | 2019-05-31 | Икс-Чем, Инк. | Способы мечения днк-кодированных библиотек |
NZ739931A (en) | 2012-07-13 | 2019-08-30 | X Chem Inc | Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases |
EP3673064A4 (fr) * | 2017-08-24 | 2021-05-26 | Takara Bio USA, Inc. | Procédés de production d'acides nucléiques à l'aide d'oligonucléotides modifiés par un stimulus |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59161398A (ja) * | 1983-03-02 | 1984-09-12 | Mitsui Toatsu Chem Inc | デオキシリボ核酸の切断処理方法及び装置 |
EP0590689B2 (fr) | 1985-03-30 | 2006-08-16 | KAUFFMAN, Stuart A. | Procédé d'obtention d'ADN, ARN, peptides, polypeptides ou protéines, par une technique de recombinaison d'ADN |
US4865968A (en) * | 1985-04-01 | 1989-09-12 | The Salk Institute For Biological Studies | DNA sequencing |
US5674679A (en) * | 1991-09-27 | 1997-10-07 | Amersham Life Science, Inc. | DNA cycle sequencing |
GB9208733D0 (en) * | 1992-04-22 | 1992-06-10 | Medical Res Council | Dna sequencing method |
JPH07509365A (ja) * | 1992-07-31 | 1995-10-19 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | ポリヌクレオチド類の3’末端に特定配列を導入する方法 |
US6165793A (en) * | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
CN1123328A (zh) * | 1994-11-17 | 1996-05-29 | 中国科学院上海生物化学研究所 | 高温、高传真脱氧核糖核酸(DNA)聚合酶(HiFi Bst) |
US5830655A (en) * | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
JPH1066576A (ja) | 1996-08-07 | 1998-03-10 | Novo Nordisk As | 突出末端を有する2本鎖dna及びこれを用いたdnaのシャフリング方法 |
GB9701425D0 (en) | 1997-01-24 | 1997-03-12 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
US6159687A (en) | 1997-03-18 | 2000-12-12 | Novo Nordisk A/S | Methods for generating recombined polynucleotides |
WO1998041653A1 (fr) | 1997-03-18 | 1998-09-24 | Novo Nordisk A/S | Methode de constitution in vitro de bibliotheque d'adn |
AU738461B2 (en) | 1997-03-18 | 2001-09-20 | Novozymes A/S | Shuffling of heterologous DNA sequences |
DE69840382D1 (de) | 1997-03-18 | 2009-02-05 | Novozymes As | Methode zur herstellung einer bibliothek mittels dna-shuffling |
US6153410A (en) * | 1997-03-25 | 2000-11-28 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
GB9712512D0 (en) | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
DE19741714C2 (de) | 1997-09-22 | 2002-03-21 | Inst Molekulare Biotechnologie | Verfahren zur Synthese und Amplifikation von Nukleinsäuren |
CA2307324A1 (fr) | 1997-10-17 | 1999-04-29 | The Procter & Gamble Company | Techniques de production d'enzymes amylase |
AR017831A1 (es) | 1997-12-10 | 2001-10-24 | Pioneer Hi Bred Int | Metodo para alterar la composicion de aminoacidos de una proteina nativa de interes, proteina elaborada, y polinucleotido |
DE19812103A1 (de) | 1998-03-19 | 1999-09-23 | Bernauer Annette | Verfahren zur Synthese von Nucleinsäuremolekülen |
FR2782323B1 (fr) * | 1998-08-12 | 2002-01-11 | Proteus | Procede de production in vitro de sequences polynucleotidiques recombinees, banques de sequences et sequences ainsi obtenues |
IL138002A0 (en) | 1999-01-19 | 2001-10-31 | Maxygen Inc | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
US6534292B1 (en) * | 2000-05-08 | 2003-03-18 | Genencor International, Inc. | Methods for forming recombined nucleic acids |
-
2000
- 2000-07-10 US US09/613,535 patent/US6994963B1/en not_active Expired - Lifetime
-
2001
- 2001-07-10 AU AU2001273461A patent/AU2001273461A1/en not_active Abandoned
- 2001-07-10 WO PCT/US2001/022195 patent/WO2002004630A2/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US6994963B1 (en) | 2006-02-07 |
WO2002004630A2 (fr) | 2002-01-17 |
WO2002004630A3 (fr) | 2002-08-29 |
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