AU2001273461A1 - Methods for recombinatorial nucleic acid synthesis - Google Patents

Methods for recombinatorial nucleic acid synthesis

Info

Publication number
AU2001273461A1
AU2001273461A1 AU2001273461A AU7346101A AU2001273461A1 AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1 AU 2001273461 A AU2001273461 A AU 2001273461A AU 7346101 A AU7346101 A AU 7346101A AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1
Authority
AU
Australia
Prior art keywords
recombinatorial
methods
nucleic acid
acid synthesis
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273461A
Other languages
English (en)
Inventor
Andrew D. Ellington
George L. Murphy
Robert A Setterquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ambion Inc
Original Assignee
Ambion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambion Inc filed Critical Ambion Inc
Publication of AU2001273461A1 publication Critical patent/AU2001273461A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001273461A 2000-07-10 2001-07-10 Methods for recombinatorial nucleic acid synthesis Abandoned AU2001273461A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/613,535 2000-07-10
US09/613,535 US6994963B1 (en) 2000-07-10 2000-07-10 Methods for recombinatorial nucleic acid synthesis
PCT/US2001/022195 WO2002004630A2 (fr) 2000-07-10 2001-07-10 Procédés de synthèse recombinatoire d"acides nucléiques

Publications (1)

Publication Number Publication Date
AU2001273461A1 true AU2001273461A1 (en) 2002-01-21

Family

ID=24457683

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273461A Abandoned AU2001273461A1 (en) 2000-07-10 2001-07-10 Methods for recombinatorial nucleic acid synthesis

Country Status (3)

Country Link
US (1) US6994963B1 (fr)
AU (1) AU2001273461A1 (fr)
WO (1) WO2002004630A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7332308B1 (en) * 1999-05-21 2008-02-19 The Penn State Research Foundation Incrementally truncated nucleic acids and methods of making same
US7871799B2 (en) * 2002-11-22 2011-01-18 Lawrence Livermore National Security, Llc Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions
TWI333977B (en) * 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
US7501254B2 (en) * 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
DK2121920T3 (da) * 2007-03-01 2011-11-21 Symphogen As Fremgangsmåde til kloning af sammenhørende antistoffer
KR20110058861A (ko) * 2008-08-29 2011-06-01 심포젠 에이/에스 조류 유래 항체의 클로닝 방법
KR102091207B1 (ko) 2009-02-13 2020-03-20 엑스-켐, 인크. Ｄｎａ―코딩된 라이브러리의 생성 및 스크리닝 방법
EA032438B1 (ru) 2011-09-07 2019-05-31 Икс-Чем, Инк. Способы мечения днк-кодированных библиотек
NZ739931A (en) 2012-07-13 2019-08-30 X Chem Inc Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
EP3673064A4 (fr) * 2017-08-24 2021-05-26 Takara Bio USA, Inc. Procédés de production d'acides nucléiques à l'aide d'oligonucléotides modifiés par un stimulus

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59161398A (ja) * 1983-03-02 1984-09-12 Mitsui Toatsu Chem Inc デオキシリボ核酸の切断処理方法及び装置
EP0590689B2 (fr) 1985-03-30 2006-08-16 KAUFFMAN, Stuart A. Procédé d'obtention d'ADN, ARN, peptides, polypeptides ou protéines, par une technique de recombinaison d'ADN
US4865968A (en) * 1985-04-01 1989-09-12 The Salk Institute For Biological Studies DNA sequencing
US5674679A (en) * 1991-09-27 1997-10-07 Amersham Life Science, Inc. DNA cycle sequencing
GB9208733D0 (en) * 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
JPH07509365A (ja) * 1992-07-31 1995-10-19 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング ポリヌクレオチド類の３’末端に特定配列を導入する方法
US6165793A (en) * 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
CN1123328A (zh) * 1994-11-17 1996-05-29 中国科学院上海生物化学研究所 高温、高传真脱氧核糖核酸(DNA)聚合酶(HiFi Bst)
US5830655A (en) * 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
JPH1066576A (ja) 1996-08-07 1998-03-10 Novo Nordisk As 突出末端を有する２本鎖ｄｎａ及びこれを用いたｄｎａのシャフリング方法
GB9701425D0 (en) 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
US6159687A (en) 1997-03-18 2000-12-12 Novo Nordisk A/S Methods for generating recombined polynucleotides
WO1998041653A1 (fr) 1997-03-18 1998-09-24 Novo Nordisk A/S Methode de constitution in vitro de bibliotheque d'adn
AU738461B2 (en) 1997-03-18 2001-09-20 Novozymes A/S Shuffling of heterologous DNA sequences
DE69840382D1 (de) 1997-03-18 2009-02-05 Novozymes As Methode zur herstellung einer bibliothek mittels dna-shuffling
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
GB9712512D0 (en) 1997-06-16 1997-08-20 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
DE19741714C2 (de) 1997-09-22 2002-03-21 Inst Molekulare Biotechnologie Verfahren zur Synthese und Amplifikation von Nukleinsäuren
CA2307324A1 (fr) 1997-10-17 1999-04-29 The Procter & Gamble Company Techniques de production d'enzymes amylase
AR017831A1 (es) 1997-12-10 2001-10-24 Pioneer Hi Bred Int Metodo para alterar la composicion de aminoacidos de una proteina nativa de interes, proteina elaborada, y polinucleotido
DE19812103A1 (de) 1998-03-19 1999-09-23 Bernauer Annette Verfahren zur Synthese von Nucleinsäuremolekülen
FR2782323B1 (fr) * 1998-08-12 2002-01-11 Proteus Procede de production in vitro de sequences polynucleotidiques recombinees, banques de sequences et sequences ainsi obtenues
IL138002A0 (en) 1999-01-19 2001-10-31 Maxygen Inc Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6534292B1 (en) * 2000-05-08 2003-03-18 Genencor International, Inc. Methods for forming recombined nucleic acids

Also Published As

Publication number Publication date
US6994963B1 (en) 2006-02-07
WO2002004630A2 (fr) 2002-01-17
WO2002004630A3 (fr) 2002-08-29

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