ATE308982T1 - Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen - Google Patents
Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionenInfo
- Publication number
- ATE308982T1 ATE308982T1 AT01911580T AT01911580T ATE308982T1 AT E308982 T1 ATE308982 T1 AT E308982T1 AT 01911580 T AT01911580 T AT 01911580T AT 01911580 T AT01911580 T AT 01911580T AT E308982 T1 ATE308982 T1 AT E308982T1
- Authority
- AT
- Austria
- Prior art keywords
- aromatic
- treatment
- infections
- diseases
- prophylaxis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17979500P | 2000-02-02 | 2000-02-02 | |
EP00102050 | 2000-02-02 | ||
PCT/EP2001/001126 WO2001056553A2 (en) | 2000-02-02 | 2001-02-02 | Pharmaceutically active aromatic guanylhydrazones |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE308982T1 true ATE308982T1 (de) | 2005-11-15 |
Family
ID=26070491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01911580T ATE308982T1 (de) | 2000-02-02 | 2001-02-02 | Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen |
Country Status (7)
Country | Link |
---|---|
US (2) | US20030203969A1 (de) |
EP (1) | EP1255541B1 (de) |
AT (1) | ATE308982T1 (de) |
AU (1) | AU2001240578A1 (de) |
DE (1) | DE60114772T2 (de) |
ES (1) | ES2250363T3 (de) |
WO (1) | WO2001056553A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002000613A2 (en) * | 2000-06-27 | 2002-01-03 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
WO2003006426A1 (en) * | 2001-07-13 | 2003-01-23 | Axxima Pharmaceuticals Ag | Aromatic guanylhydrazones as effective compounds against neurodiseases |
WO2003024407A2 (en) * | 2001-09-21 | 2003-03-27 | Message Pharmaceuticals, Inc. | Inhibitors of rnase p proteins as antibacterial compounds |
PL370480A1 (en) * | 2001-11-07 | 2005-05-30 | F.Hoffmann-La Roche Ag | Aminopyrimidines and pyridines |
EP1389480A1 (de) * | 2002-08-14 | 2004-02-18 | Mondobiotech Interferon SA | Therapeutische Anwendung von Guanylhydrazone zur Hemmung von CD83 abhängige Verfahren und Reifung der dendritischen Zellen |
EP1413300A1 (de) * | 2002-10-26 | 2004-04-28 | Mondobiotech SA | Pyrimidinium-Guanidiniminoethylphenyl-Guanidinoalkyl-Amine und Guanidiniminoethylphenyl-Guanidinoalkylamine als pharmazeutische Wirkstoffe |
US20040224916A1 (en) | 2003-01-14 | 2004-11-11 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
WO2005051318A2 (en) * | 2003-11-24 | 2005-06-09 | Viropharma Incorporated | Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
CN102936212A (zh) * | 2004-08-17 | 2013-02-20 | 辉凌公司 | 脒腙化合物、组合物、制备方法及使用方法 |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
TWI375560B (en) * | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
DE102006028371A1 (de) * | 2006-06-19 | 2007-12-20 | Rheinische Friedrich-Wilhelms Universität | Mittel gegen Malaria |
EP2131858A4 (de) * | 2007-03-20 | 2011-11-23 | Cadila Pharmaceuticals Ltd | P38-hemmer |
EP2155675B1 (de) | 2007-06-12 | 2014-02-19 | Provid Pharmaceuticals, Inc. | Kinaseinhibitoren, deren zusammensetzungen und verfahren ihrer anwendung |
RU2477271C2 (ru) * | 2011-01-12 | 2013-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) | Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения |
WO2013100208A1 (ja) | 2011-12-28 | 2013-07-04 | 京都府公立大学法人 | 角膜内皮細胞の培養正常化 |
US10813920B2 (en) | 2013-11-14 | 2020-10-27 | The Doshisha | Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage |
CN110331110B (zh) * | 2019-07-26 | 2021-07-13 | 中南民族大学 | 一种利用废糖蜜和细菌高效还原水中六价铬并回收铬的方法 |
WO2023230431A1 (en) * | 2022-05-23 | 2023-11-30 | Glaxo Wellcome Uk Limited | Inhibitors of deoxyhypusine synthase for the treatment and prevention of respiratory virus infections |
CN116102468B (zh) * | 2023-02-22 | 2024-07-09 | 中国科学技术大学 | 靶向人脂质运载蛋白2的先导化合物或其药学上可接受的盐及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US573684A (en) * | 1896-12-22 | Alexander hill motes | ||
US6008255A (en) * | 1994-01-21 | 1999-12-28 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
US5599984A (en) * | 1994-01-21 | 1997-02-04 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
CA2271693C (en) * | 1996-11-15 | 2009-01-20 | The Picower Institute For Medical Research | Guanylhydrazones useful for treating diseases associated with t cell activation |
-
2001
- 2001-02-02 AU AU2001240578A patent/AU2001240578A1/en not_active Abandoned
- 2001-02-02 DE DE60114772T patent/DE60114772T2/de not_active Expired - Fee Related
- 2001-02-02 ES ES01911580T patent/ES2250363T3/es not_active Expired - Lifetime
- 2001-02-02 EP EP01911580A patent/EP1255541B1/de not_active Expired - Lifetime
- 2001-02-02 WO PCT/EP2001/001126 patent/WO2001056553A2/en active IP Right Grant
- 2001-02-02 AT AT01911580T patent/ATE308982T1/de not_active IP Right Cessation
- 2001-02-02 US US10/182,752 patent/US20030203969A1/en not_active Abandoned
-
2005
- 2005-02-07 US US11/052,325 patent/US20050171176A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2001240578A1 (en) | 2001-08-14 |
US20050171176A1 (en) | 2005-08-04 |
DE60114772T2 (de) | 2006-07-20 |
EP1255541B1 (de) | 2005-11-09 |
US20030203969A1 (en) | 2003-10-30 |
ES2250363T3 (es) | 2006-04-16 |
WO2001056553A3 (en) | 2002-03-28 |
EP1255541A2 (de) | 2002-11-13 |
WO2001056553A2 (en) | 2001-08-09 |
DE60114772D1 (de) | 2005-12-15 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 1255541 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |