AR110068A2 - 2-amino-7,8-dihidro-6h-pirido[4,3-d]pirimidina-5-onas - Google Patents
2-amino-7,8-dihidro-6h-pirido[4,3-d]pirimidina-5-onasInfo
- Publication number
- AR110068A2 AR110068A2 ARP170103158A ARP170103158A AR110068A2 AR 110068 A2 AR110068 A2 AR 110068A2 AR P170103158 A ARP170103158 A AR P170103158A AR P170103158 A ARP170103158 A AR P170103158A AR 110068 A2 AR110068 A2 AR 110068A2
- Authority
- AR
- Argentina
- Prior art keywords
- substituted
- unsubstituted
- amino
- phenyl
- group
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Reivindicación 1: Un compuesto con la fórmula [1], o un esteroisómero, tautómero, sal farmacéuticamente aceptable, o promedicamento del mismo, en donde: Rᵃ se selecciona de un grupo compuesto de (1) hidrógeno, (2) halógeno, (3) hidroxilo, (4) C₁₋₆ alcoxi, (5) tiol, (6) C₁₋₆ alquiltiol, (7) C₁₋₆ alquilo sustituido o no sustituido, (8) amino o amino sustituido, (9) arilo sustituido o no sustituido, (10) heteroarilo sustituido o no sustituido, y (11) heterociclilo sustituido o no sustituido; R se selecciona de un grupo compuesto de: (1) hidrógeno, (2) C₁₋₆ alquilo sustituido o no sustituido, (3) C₂₋₆ alquenilo sustituido o no sustituido, (4) C₂₋₆ alquinilo sustituido o no sustituido, (5) C₂₋₆ cicloalquilo sustituido o no sustituido, (6) C₅₋₇ cicloalquenilo sustituido o no sustituido, (7) arilo sustituido o no sustituido, (8) heteroarilo sustituido o no sustituido, y (9) heterociclilo sustituido o no sustituido; Rᵇ se selecciona de un grupo compuesto de (1) cicloalquilo C₃₋₇ sustituido o no sustituido, (2) cicloalquenilo C₅₋₇ sustituido o no sustituido, (3) arilo sustituido o no sustituido, (4) heteroarilo sustituido o no sustituido, y (5) heterociclilo sustituido o no sustituido; y con la condición de que cuando Rᵃ es amino, entonces Rᵇ no es fenilo, 4-alquilo-fenilo, 4-alcoxi-fenilo, o 4-halo-fenilo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72279605P | 2005-09-30 | 2005-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR110068A2 true AR110068A2 (es) | 2019-02-20 |
Family
ID=40059303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP170103158A AR110068A2 (es) | 2005-09-30 | 2017-11-13 | 2-amino-7,8-dihidro-6h-pirido[4,3-d]pirimidina-5-onas |
Country Status (6)
Country | Link |
---|---|
CN (1) | CN101287734B (es) |
AR (1) | AR110068A2 (es) |
SI (1) | SI1928875T1 (es) |
SV (1) | SV2008002856A (es) |
UA (1) | UA93522C2 (es) |
ZA (1) | ZA200803658B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010034670A2 (en) * | 2008-09-26 | 2010-04-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Host cell kinases as targets for antiviral therapies against hcv infection |
KR20170113683A (ko) * | 2008-11-28 | 2017-10-12 | 노파르티스 아게 | 피리도〔4,3-d〕피리미딘 유래의 hsp90-억제제 및 her2 억제제를 포함하는 제약 조합물 |
RU2519673C2 (ru) * | 2008-11-28 | 2014-06-20 | Новартис Аг | Комбинации ингибитора hsp90 |
EP3292120B1 (en) * | 2015-05-04 | 2019-06-19 | H. Hoffnabb-La Roche Ag | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections |
CN113056475A (zh) * | 2018-11-30 | 2021-06-29 | 中外制药株式会社 | 用于肽化合物或酰胺化合物的脱保护方法和在固相反应中的树脂脱除方法以及用于生产肽化合物的方法 |
CN109846886A (zh) * | 2019-03-26 | 2019-06-07 | 中国医学科学院基础医学研究所 | Nvp-hsp990在制备治疗癫痫的药物中的用途 |
CN114681463B (zh) * | 2022-04-29 | 2024-03-15 | 暨南大学 | Hsp990在制备预防和/或治疗腺病毒感染的药物中的应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6165873A (ja) * | 1984-09-07 | 1986-04-04 | Mitsui Petrochem Ind Ltd | 2−ピペラジノピリミジン誘導体 |
US4734418A (en) * | 1984-12-14 | 1988-03-29 | Mitsui Petrochemical Industries, Ltd. | Quinazoline compounds and antihypertensives |
IL85347A0 (en) * | 1987-02-11 | 1988-07-31 | May & Baker Ltd | Cyclic diones |
-
2006
- 2006-09-28 CN CN2006800365004A patent/CN101287734B/zh not_active Expired - Fee Related
- 2006-09-28 SI SI200631090T patent/SI1928875T1/sl unknown
- 2006-09-28 UA UAA200805390A patent/UA93522C2/ru unknown
-
2008
- 2008-03-28 SV SV2008002856A patent/SV2008002856A/es active IP Right Grant
- 2008-04-25 ZA ZA200803658A patent/ZA200803658B/xx unknown
-
2017
- 2017-11-13 AR ARP170103158A patent/AR110068A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
UA93522C2 (en) | 2011-02-25 |
SI1928875T1 (sl) | 2011-10-28 |
SV2008002856A (es) | 2008-06-30 |
ZA200803658B (en) | 2009-09-30 |
CN101287734A (zh) | 2008-10-15 |
CN101287734B (zh) | 2011-07-20 |
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