AP2024A - Microbicidal pyrimidine or triazine for preventingsexual HIV transmission - Google Patents
Microbicidal pyrimidine or triazine for preventingsexual HIV transmissionInfo
- Publication number
- AP2024A AP2024A AP2004003182A AP2004003182A AP2024A AP 2024 A AP2024 A AP 2024A AP 2004003182 A AP2004003182 A AP 2004003182A AP 2004003182 A AP2004003182 A AP 2004003182A AP 2024 A AP2024 A AP 2024A
- Authority
- AP
- ARIPO
- Prior art keywords
- preventingsexual
- triazine
- hiv transmission
- microbicidal
- pyrimidine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02076897 | 2002-05-13 | ||
PCT/EP2003/050158 WO2003094920A1 (en) | 2002-05-13 | 2003-05-13 | Microbicidal pyrimidine or triazine for preventing sexual hiv transmission |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2004003182A0 AP2004003182A0 (en) | 2004-12-31 |
AP2024A true AP2024A (en) | 2009-08-11 |
Family
ID=29414777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2004003182A AP2024A (en) | 2002-05-13 | 2003-05-13 | Microbicidal pyrimidine or triazine for preventingsexual HIV transmission |
Country Status (27)
Country | Link |
---|---|
US (4) | US7935710B2 (zh) |
EP (1) | EP1505980B1 (zh) |
JP (2) | JP4530848B2 (zh) |
KR (1) | KR101095358B1 (zh) |
CN (2) | CN1668305B (zh) |
AP (1) | AP2024A (zh) |
AR (1) | AR039540A1 (zh) |
AT (1) | ATE376420T1 (zh) |
AU (1) | AU2003240844B2 (zh) |
BR (2) | BRPI0310021B8 (zh) |
CA (1) | CA2486078C (zh) |
CY (1) | CY1110249T1 (zh) |
DE (1) | DE60317060T2 (zh) |
DK (1) | DK1505980T3 (zh) |
EA (1) | EA011298B1 (zh) |
ES (1) | ES2294291T3 (zh) |
HK (1) | HK1173141A1 (zh) |
HR (1) | HRP20041177B1 (zh) |
IL (1) | IL165174A (zh) |
MX (1) | MXPA04011392A (zh) |
NO (2) | NO331030B1 (zh) |
NZ (1) | NZ536976A (zh) |
PL (1) | PL215128B1 (zh) |
PT (1) | PT1505980E (zh) |
SI (1) | SI1505980T1 (zh) |
WO (1) | WO2003094920A1 (zh) |
ZA (1) | ZA200409984B (zh) |
Families Citing this family (50)
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TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
AR039540A1 (es) * | 2002-05-13 | 2005-02-23 | Tibotec Pharm Ltd | Compuestos microbicidas con contenido de pirimidina o triazina |
BR0313059B8 (pt) | 2002-07-29 | 2021-07-27 | Rigel Pharmaceuticals | composto, e, composição farmacêutica |
CN102151270A (zh) | 2003-02-07 | 2011-08-17 | 詹森药业有限公司 | 预防hiv感染的嘧啶衍生物 |
CL2004000303A1 (es) * | 2003-02-20 | 2005-04-08 | Tibotec Pharm Ltd | Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih. |
RS53109B (en) | 2003-07-30 | 2014-06-30 | Rigel Pharmaceuticals Inc. | 2,4 PIRIMIDINDIAMINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES |
ITMI20031640A1 (it) | 2003-08-08 | 2005-02-09 | Mipharm S P A | Base per gel bioadesivi. |
UA93354C2 (ru) | 2004-07-09 | 2011-02-10 | Гилиад Сайенсиз, Инк. | Местный противовирусный препарат |
ATE540035T1 (de) | 2004-11-24 | 2012-01-15 | Rigel Pharmaceuticals Inc | Spiro-2,4-pyrimidindiamin-verbindungen und ihre verwendungen |
BRPI0606318B8 (pt) | 2005-01-19 | 2021-05-25 | Rigel Pharmaceuticals Inc | composto, composição, e, uso de um composto |
BRPI0607811B8 (pt) * | 2005-02-18 | 2021-05-25 | Janssen R & D Ireland | derivados de óxido de pirimidina de 2-(4-cianofenilamino) inibidores de hiv, composição farmacêutica compreendendo os mesmos, processo para preparar a referida composição e uso |
US20070203161A1 (en) | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
WO2006133426A2 (en) | 2005-06-08 | 2006-12-14 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
WO2007071199A1 (fr) * | 2005-12-22 | 2007-06-28 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Composes de 2,4-disubstituee amido-6-substituee-[1,3,5]triazine ou de 1,3-pyrimidine, leurs procedes d'elaboration, et preparations pharmaceutiques les contenant et leurs utilisations |
ES2622493T3 (es) | 2006-02-24 | 2017-07-06 | Rigel Pharmaceuticals, Inc. | Composiciones y métodos para la inhibición de la ruta de JAK |
RU2008152195A (ru) | 2006-06-15 | 2010-07-20 | БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) | 2-анилино-4-(гетероциклил)аминопиримидины, как ингибиторы протеинкиназы с-альфа |
AU2007257701A1 (en) | 2006-06-15 | 2007-12-21 | Boehringer Ingelheim International Gmbh | 2-anilino-4-aminoalkyleneaminopyrimidines |
BRPI0722383A2 (pt) | 2006-12-08 | 2012-06-05 | Irm Llc | compostos inibidores de proteìna quinase, composições contendo os mesmos bem como seus usos |
ES2550152T3 (es) * | 2006-12-13 | 2015-11-04 | F. Hoffmann-La Roche Ag | Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa |
US9006243B2 (en) * | 2006-12-29 | 2015-04-14 | Janssen R&D Ireland | HIV inhibiting 6-substituted pyrimidines |
ES2618057T3 (es) * | 2006-12-29 | 2017-06-20 | Janssen Sciences Ireland Uc | Pirimidinas 5,6-sustituidas inhibidoras del VIH |
CA2702674C (en) | 2007-10-19 | 2016-05-03 | Avila Therapeutics, Inc. | Heteroaryl compounds and uses thereof |
US7989465B2 (en) | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
WO2009143389A1 (en) | 2008-05-21 | 2009-11-26 | Ariad Pharmaceuticals, Inc. | Phosphorous derivatives as kinase inhibitors |
US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
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US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
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US10426761B2 (en) | 2011-04-19 | 2019-10-01 | Arms Pharmaceutical, Llc | Method for treatment of disease caused or aggravated by microorganisms or relieving symptoms thereof |
US20130039959A1 (en) * | 2011-04-19 | 2013-02-14 | Brian Vincent Sokol | Method of inhibiting hiv and barrier-forming composition therefor |
CN103619341A (zh) | 2011-04-19 | 2014-03-05 | Arms制药有限公司 | 抑制有害微生物的方法及其阻隔形成组合物 |
MX360404B (es) | 2011-05-04 | 2018-10-31 | Ariad Pharma Inc | Compuestos para inhibir la proliferacion celular en canceres transmitidos por egfr. |
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GB201204756D0 (en) | 2012-03-19 | 2012-05-02 | Lewi Paulus J | Triazines with suitable spacers for treatment and/or prevention of HIV infections |
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CN102675212B (zh) * | 2012-05-09 | 2014-11-05 | 昆明理工大学 | N-取代苯基-2-((1h-苯并咪唑-2-基)巯基)乙酰胺类衍生物及其用途 |
CA2891412A1 (en) | 2012-11-20 | 2014-05-30 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase |
US9611283B1 (en) | 2013-04-10 | 2017-04-04 | Ariad Pharmaceuticals, Inc. | Methods for inhibiting cell proliferation in ALK-driven cancers |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
JP6466107B2 (ja) * | 2014-09-04 | 2019-02-06 | 東ソー・ファインケム株式会社 | 4−フェニルチオ−5−(トリフルオロメチル)ピリミジン誘導体及びその製造方法 |
CN105085410B (zh) * | 2015-08-21 | 2017-10-10 | 武汉工程大学 | 一种二芳基嘧啶类hiv‑1抑制剂及其制备方法 |
WO2017077520A1 (en) | 2015-11-06 | 2017-05-11 | Ineb - Instituto Nacional De Engenharia Biomédica | A composition for use in a method for prevention or treatment of human immunodeficiency virus infections |
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CN106866628A (zh) * | 2017-02-27 | 2017-06-20 | 武汉工程大学 | 一种芳基杂芳基嘧啶类hiv‑1逆转录酶抑制剂及其制备方法 |
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CN109053613A (zh) * | 2018-07-04 | 2018-12-21 | 复旦大学 | 含有联苯结构的二芳基三嗪类化合物及其制备方法和用途 |
MX2021003723A (es) * | 2018-12-04 | 2021-05-13 | Virox Tech Inc | Composiciones antimicrobianas que contienen n-alquil gamma butirolactama de c3-c5 y usos de las mismas. |
US20220033851A1 (en) * | 2020-08-03 | 2022-02-03 | Roger B. Swartz | mRNA, episomal and genomic integrated lentiviral and gammaretroviral vector expression of dimeric immunoglobulin A and polymeric immunoglobulin A to Enable Mucosal and Hematological Based Immunity/Protection via Gene Therapy for Allergens, viruses, HIV, bacteria, pneumonia, infections, pathology associated proteins, systemic pathologies, cancer, toxins and unnatural viruses. CAR engineered and non-CAR engineered immune cell expression of dimeric immunoglobulin A and polymeric immunoglobulin A. |
AU2022323509A1 (en) | 2021-08-03 | 2024-02-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hiv-1 vaccination and samt-247 microbicide to prevent hiv-1 infection |
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WO1999050256A1 (en) * | 1998-03-27 | 1999-10-07 | Janssen Pharmaceutica N.V. | Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections |
WO2000027828A2 (en) * | 1998-11-10 | 2000-05-18 | Janssen Pharmaceutica N.V. | 2,4-disubstituted triazine derivatives with anti hiv activity |
WO2000027825A1 (en) * | 1998-11-10 | 2000-05-18 | Janssen Pharmaceutica N.V. | Hiv replication inhibiting pyrimidines |
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- 2003-05-13 JP JP2004503005A patent/JP4530848B2/ja not_active Expired - Lifetime
- 2003-05-13 BR BRPI0310021A patent/BRPI0310021B8/pt not_active IP Right Cessation
- 2003-05-13 DE DE60317060T patent/DE60317060T2/de not_active Expired - Lifetime
- 2003-05-13 BR BR122014006936A patent/BR122014006936B8/pt active IP Right Grant
- 2003-05-13 PT PT03730208T patent/PT1505980E/pt unknown
- 2003-05-13 NZ NZ536976A patent/NZ536976A/en not_active IP Right Cessation
- 2003-05-13 WO PCT/EP2003/050158 patent/WO2003094920A1/en active IP Right Grant
- 2003-05-13 CN CN038163594A patent/CN1668305B/zh not_active Expired - Lifetime
- 2003-05-13 MX MXPA04011392A patent/MXPA04011392A/es active IP Right Grant
- 2003-05-13 US US10/514,361 patent/US7935710B2/en active Active
- 2003-05-13 ES ES03730208T patent/ES2294291T3/es not_active Expired - Lifetime
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- 2003-05-13 PL PL373840A patent/PL215128B1/pl unknown
- 2003-05-13 DK DK03730208T patent/DK1505980T3/da active
- 2003-05-13 CA CA2486078A patent/CA2486078C/en not_active Expired - Lifetime
- 2003-05-13 AT AT03730208T patent/ATE376420T1/de active
- 2003-05-13 SI SI200331043T patent/SI1505980T1/sl unknown
- 2003-05-13 AP AP2004003182A patent/AP2024A/xx active
- 2003-05-13 EA EA200401494A patent/EA011298B1/ru unknown
- 2003-05-13 AU AU2003240844A patent/AU2003240844B2/en not_active Expired
- 2003-05-13 KR KR1020047018312A patent/KR101095358B1/ko active IP Right Grant
- 2003-05-13 CN CN201110374093.0A patent/CN102558070B/zh not_active Expired - Lifetime
-
2004
- 2004-11-11 IL IL165174A patent/IL165174A/en active IP Right Grant
- 2004-12-01 NO NO20045267A patent/NO331030B1/no not_active IP Right Cessation
- 2004-12-09 ZA ZA200409984A patent/ZA200409984B/xx unknown
- 2004-12-10 HR HRP20041177AA patent/HRP20041177B1/hr not_active IP Right Cessation
-
2008
- 2008-01-22 CY CY20081100084T patent/CY1110249T1/el unknown
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2010
- 2010-05-07 JP JP2010107209A patent/JP5256244B2/ja not_active Expired - Lifetime
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2011
- 2011-02-22 NO NO20110298A patent/NO334067B1/no not_active IP Right Cessation
- 2011-03-08 US US13/043,174 patent/US20110165093A1/en not_active Abandoned
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2013
- 2013-01-07 HK HK13100210.9A patent/HK1173141A1/zh not_active IP Right Cessation
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2016
- 2016-12-23 US US15/389,662 patent/US20170100399A1/en not_active Abandoned
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2020
- 2020-07-16 US US16/930,581 patent/US20200345733A1/en not_active Abandoned
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WO1999050250A1 (en) * | 1998-03-27 | 1999-10-07 | Janssen Pharmaceutica N.V. | Hiv inhibiting pyrimidine derivatives |
WO1999050256A1 (en) * | 1998-03-27 | 1999-10-07 | Janssen Pharmaceutica N.V. | Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections |
WO2000027828A2 (en) * | 1998-11-10 | 2000-05-18 | Janssen Pharmaceutica N.V. | 2,4-disubstituted triazine derivatives with anti hiv activity |
WO2000027825A1 (en) * | 1998-11-10 | 2000-05-18 | Janssen Pharmaceutica N.V. | Hiv replication inhibiting pyrimidines |
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